Clinical aspects of glucocorticoid sensitivity

Steroids

Volumn 61, Issue 4, 1996, Pages 157-160

  Lamberts, S W J ^a,b   Huizenga, A T M ^a   De Lange, P ^a   De Jong, F H ^a   Koper, J W ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

asthma; cytokine; glucocorticoid receptor; glucocorticoids; immune function; side effect

Indexed keywords

CYCLOSPORIN; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; METHOTREXATE;

ASTHMA; CONFERENCE PAPER; HORMONAL THERAPY; HORMONE RESISTANCE; HORMONE SENSITIVITY; HUMAN; IMMUNE RESPONSE; IMMUNOMODULATION; RECEPTOR GENE; RHEUMATOID ARTHRITIS;

EID: 0029862986     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0039-128X(96)00005-0     Document Type: Conference Paper

References (37)

1. Boumpas DT, Chrousos GP, Wilder RL, Cupps TR, Balow JE (1993). Glucocorticoid therapy for immune-mediated diseases: basic and clinical correlates. Ann Int Med 119:1198-1208.
2. Hench PS, Kendall EC, Slocumb CH, Policy HF (1950). Effects of cortisone acetate and pituitary ACTH on rheumatoid arthritis, rheumatic fever and certain other conditions. Arch Intern Med 48:545-566.
3. Bollet AJ, Black R, Bunim JJ (1955). Major undesirable sideeffects resulting from prednisolone and prednisone. JAMA 158:459-463.
4. Saag KG, Oehnke R, Caldwell JR, Brasington R, Burmeister LF, Zimmerman B, Kohler JA, Furst DE (1994). Low dose long-term corticosteroid therapy in rheumatoid arthritis: an analysis of serious adverse events. Am J Med 96:115-123.
5. Axelrod L (1976) Glucocorticoid therapy. Medicine (Baltimore) 55: 39-65.
6. Schwartz HJ, Lowell FC, Melby JC (1968). Steroid resistance in bronchial asthma. Ann Intern Med 69:493-499.
7. Carmichael J, Paterson IC, Diaz P, Crompton GK, Kay AB, Grant IWB (1981). Corticosteroid resistance in chronic asthma. Br Med J 282:1419-1422.
8. Corkill MM, Kirkham B, Chikanza IC, Gibson T, Panayi GS (1990). Intramuscular methylprednisolone induction of chrysotherapy: a 24 week randomised double blind placebo controlled trial. Br J Rheumatol 29:274-279.
9. Kirkham B, Corkill MM, Davison SC, Panayi GS (1991). Response to glucocorticoid treatment in rheumatoid arthritis: in vitro cell mediated immune assay predicts in vivo response. J Rheumatol 18:30-33.
10. Walker KB, Potter JM, House AK (1985). Variable inhibition of mitogen-induced blastogenesis in human lymphocytes by prednisolone in vitro. Transplant Proc 17:1676-1678.
11. Langhoff E, Laderfoged J, Jacobsen BK (1986). Recipient lymphocyte sensitivity to methyl prednisolone affects cadaver kidney graft survival. Lancet 2:1296-1297.
12. Vingerhoeds A, Thijssen J, Schwarz F (1976). Spontaneous hypercortisolism without Cushing's syndrome. J Clin Endocrinol Metab 43:1128-1133.
13. Lamberts SWJ, Poldermans D, Zweens M, de Jong FH (1986) Familial cortisol resistance: differential diagnostic and therapeutic aspects. J Clin Endocrinol Metab 63:1328-1333.
14. Malchoff C, Favier E, Malchoff D (1990). Primary cortisol resistance presenting as isosexual precocity. J Clin Endocrinol Metab 70:503-507.
15. Brönnegard M, Werner S, Gustaffson JA (1986). Primary cortisol resistance associated with a thermolabile glucocorticoid receptor in a patient with fatigue as the only symptom. J Clin Invest 78:1270-1278.
16. Lamberts SWJ, Koper JW, Biemond P, den Holder FH, de Jong FH (1992). Cortisol receptor resistance: the variability of its clinical presentation and response to treatment. J Clin Endocrinol Metab 74:313-321.
17. Werner S, Thoren M, Gustafsson JA, Brönnegard M (1992). Glucocorticoid receptor abnormalities in fibroblasts from patients with idiopathic resistance to dexamethasone diagnosed when evaluated for adrenocortical disorders. J Clin Endocrinol Metab 75:1005-1009.
18. Hurley D, Accili D, Stratakis C (1991). Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance. J Clin Invest 87:680-686.
19. Malchoff DM, Brufsky A, Reardon G (1993). A point mutation of the human glucocorticoid receptor in primary cortisol resistance. J Clin Invest 91:1918-1925.
20. Karl M, Lamberts SWJ, Detera-Wadleigh SD (1993). Familial glucocorticoid resistance caused by a splice site deletion in the glucocorticoid receptor gene. J Clin Endocrinol Metab 76:683-689.
21. Karl M, Arai K, Stratakis ACA, Accili D, Leung DYM, Szefler SJ, Lamberts SWJ, Chrousos GP (1995). Molecular studies of the glucocorticoid receptor in patients with generalized glucocorticoid resistance and steroid resistant asthma (abstr.). 77th Annual Meeting of the Endocrine Society, Washington DC, The Endocrine Society, Bethesda, MD.
22. Nawata H, Sekiya K, Higuchi K, Kato K, Ibayashi H (1987). Decreased deoxyribonucleic acid binding of glucocorticoid-receptor complex in cultured skin fibroblasts from a patient with the glucocorticoid resistance syndrome. J Clin Endocrinol Metab 65:219-226.
23. Lippman ME, Halterman RH, Leventhal BG, Perry S, Thompson EB (1973). Glucocorticoid-binding proteins in human acute lymphoblastic leukemic blast cells. J Clin Invest 52:1715-1726.
24. Moalli P, Rosen S (1994). Glucocorticoid receptors and resistance to glucocorticoids in hematologic malignancies. Leukemia Lymphoma 15:363-374.
25. Strasser-Wozak E, Hattmann-Storfer R, Hala M, Hartman B, Fiegl M, Geley S (1995). Splice site mutations in the glucocorticoid receptor gene cause resistance to glucocorticoid-induced apoptosis in a human acute leukemic cell line. Cancer Res 55:348-353.
26. Kato GJ, Quddus FF, Shuster JJ, Boyett J, Pullen JD, Borowitz MJ, Whitehead VM, Crist WM, Leventhal BG (1993). High glucocorticoid receptor content of leukemic blasts is a favorable prognostic factor in childhood acute lymphoblastic leukemia. Blood 82:2304-2309.
27. Ray DW, Littlewood AC, Clark AJL, Davis JRE, White A (1994). Human small cell lung cancer cell lines expressing the propiomelanocortin gene have aberrant glucocorticoid receptor function. J Clin Invest 93:1625-1630.
28. Karl M, Van Wichert G, Kempter E (1994). Nelson's syndrome associated with a defect in the glucocorticoid receptor gene (abstr.). 76th Annual Meeting of the Endocrine Society, Anaheim, CA, The Endocrine Society, Bethesda, MD.
29. Chikanza IC, Panayi GS (1993). The effects of hydrocortisone on in vitro lymphocyte proliferation and interleukin-2 and -4 production in corticosteroid sensitive and resistant subjects. Eur J Clin Invest 23:845-850.
30. Sher ER, Leung DYM, Surs W, Kam JC, Zieg G, Kamada AK, Szefler SJ (1994). Steroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapy. J Clin Invest 93:33-39.
31. Norbiato G, Bevilacqua M, Vago T (1992). Cortisol resistance in acquired immunodeficiency syndrome. J Clin Endocrinol Metab 74:608-613.
32. Almawi WY, Lipman ML, Stevens AC, Zanker B, Hadro ET, Strom TB (1991). Abrogation of glucocorticoid mediated inhibition of T cell proliferation by the synergistic action of IL-1, IL-6 and IFN-gamma. J Immunol 146:3523-3537.
33. Gillis S, Crabtree GR, Smith KA (1979). Glucocorticoid-induced inhibition of T cell growth factor production. I. The effect on mitogen-induced lymphocyte proliferation. J Immunol 123:1624-1631.
34. Boumpas DT, Anastassiou ED, Older SA, Tsokos GC, Nelson DL, Balow JE (1991). Dexamethasone inhibits human interleukin 2 but not interleukin 2 receptor gene expression in vitro at the level of nuclear transcription. J Clin Invest 87:1739-1747.
35. Molijn GJ, Spek JJ, van Uffelen JCJ, de Jong FH, Brinkmann AO, Bruining HA, Lamberts SWJ (1995). Differential adaptation of glucocorticoid sensitivity of peripheral blood mononuclear leucocytes in patients with sepsis or septic shock. J Clin Endocrinol Metab 80:1799-1803.
36. Corrigan CJ, Brown JPH, Barnes NC, Szefler SJ, Tsai JJ, Frew AJ, Kay AB (1991). Glucocorticoid resistance in chronic asthma: glucocorticoid pharmacokinetics, glucocorticoid receptor characteristics and inhibition of peripheral blood T-cell proliferation by glucocorticoid in vitro. Am Rev Respir Dis 144:1016-1025.
37. Corrigan CJ, Brown JPH, Barnes NC, Tsai JJ, Frew AJ, Kay AB (1991). Glucocorticoid resistance in chronic asthma: peripheral blood T lymphocyte activation and comparison of the T lymphocyte inhibitory effects of glucocorticoids and cyclosporin A. Am Rev Respir Dis 144:1026-1032.