Bone mineral density and bone metabolism of prepubertal children with asthma after long-term treatment with inhaled corticosteroids

Pediatric Pulmonology

Volumn 24, Issue 6, 1997, Pages 379-384

  Boot, Annemieke M ^a,b   De Jongste, Johan C ^a   Verberne, Anja A P H ^a,b   Pols, Huibert A P ^a,b   De Muinck Keizer Schrama, Sabine M P F ^a,b  

^a SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Asthma; Bone mineral density; Children; Growth; Inhaled corticosteroids

Indexed keywords

CORTICOSTEROID;

ABSORPTIOMETRY; ARTICLE; ASTHMA; BONE AGE; BONE DENSITY; BONE METABOLISM; BONE MINERAL; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GROWTH RETARDATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PREPUBERTY; PRIORITY JOURNAL; STEROID THERAPY;

ADMINISTRATION, INHALATION; ASTHMA; BODY COMPOSITION; BONE AND BONES; BONE DENSITY; CHILD; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; DENSITOMETRY, X-RAY; FEMALE; GLUCOCORTICOIDS; GROWTH; HUMANS; MALE;

EID: 0031458104     PISSN: 87556863     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-0496(199712)24:6<379::AID-PPUL1>3.0.CO;2-C     Document Type: Article

References (37)

1. Toogood JH, Jennings B, Hodsman AB, Baskerville J, Fraher LJ. Effects of dose and dosing schedule of inhaled budesonide on bone turnover. J Allergy Clin Immunol. 1991; 88:572-580.
2. Jennings BH, Andersson KE, Johansson SA. Assessment of systemic effects of inhaled glucocorticosteroids: Comparison of the effects of inhaled budesonide and oral prednisolone on adrenal function and markers of bone turnover. Eur J Clin Pharm. 1991; 40:77-82.
3. Teelucksingh S, Padfield PL, Tibi L, Gough KJ, Holt PR. Inhaled corticosteroids, bone formation and osteocalcin. Lancet. 1991; 338:60-61.
4. Pouw EM, Prummel MF, Oosting H, Roos CM, Endert E. Beclomethasone inhalation decreases serum osteocalcin concentrations. Br Med J. 1991; 302:627-628.
5. Packe GE, Douglas JG, Mc Donald AF, Robins SP, Reid DM. Bone density in asthmatic patients taking high dose inhaled beclomethasone dipropionate and intermittent systemic corticosteroids. Thorax. 1992; 47:414-417.
6. Ip M, Lam K, Tam L, Kung A, Ng M. Decreased bone mineral density in premenopausal asthma patients receiving long-term inhaled steroids. Chest. 1994; 105:1722-1727.
7. Hopp RJ, Degan JA, Phelan J, Lappe J, Gallagher GC. Crosssectional study of bone density in asthmatic children. Pediatr Pulmonol. 1995; 20:189-192.
8. König P, Hillmun L, Cervantes C, Levine C, Maloney C, Douglas B, Johnson L, Allen S. Bone metabolism in children with asthma treated with inhaled beclomethasone dipropionate. J Pediatr. 1993; 122:219-226.
9. Baraldi E, Bollini MC, de Marchi A, Zacchello F. Effect of beclomethasone dipropionate on bone mineral content assessed by x-ray densitometry in asthmatic children: A longitudinal evaluation. Eur Respir J. 1994; 7:710-714.
10. Martinati LC, Bertoldo F, Gasperi E, Micelli S, Boner AL. Effect on cortical and trabecular bone mass of different anti-inflammatory treatments in preadolescent children with chronicasthma. Am J Respir Crit Care Med. 1996; 153:232-236.
11. Kinberg KA, Hopp RJ, Biven RE, Gallager JC. Bone mineral density in normal and asthmatic children. J Allergy Clin Immunol. 1994; 94:490-497.
12. Wolthers OD, Pederson S. Growth of asthmatic children during treatment with budesonide: A double blind trial. Br Med J. 1991; 303:163-165.
13. Volovitz B, Amir J, Malik H, Kauschansky A, Varsano I. Growth and pituitary-adrenal function in children with severe asthma treated with inhaled budesonide. N Engl J Med. 1993; 329:1703-1708.
14. Thomas BC, Stanhope R, Grant DB. Impaired growth in children with asthma during treatment with conventional doses of inhaled corticosteroids. Acta Paediatr. 1994; 83:196-199.
15. Boot AM, de Ridder MAJ, Pols HAP, Krenning EP, de Muinck Keizer-Schrama SMPF. Bone mineral density in children and adolescents; relation to puberty, calcium intake and physical activity. J Clin Endocrinol Metab. 1997; 82:57-62.
16. Roede MJ, Van Wieringen JC. Growth diagrams 1980, the Netherlands: Third nation wide survey. T Soc Gezondheidszorg. 1985; 63(S):1-34.
17. Weststrate JA, Deurenberg P, Tinteren H van. Body fat distribution and adiposity indices in Dutch children 0-18 year age. Int J Obes. 1989; 13:465-477.
18. Angus RM, Sambrook PN, Pocock NA, Eisman JA. A simple method for assessing calcium intake in Caucasian women. J Am Diet Assoc. 1989; 89:209-214.
19. Boot AM, Bouquet J, de Ridder MAJ, Krenning EP, de Muinck Keizer-Schrama SMPF. Determinants of body composition, measured by dual energy x-ray absorptiometry, in Dutch children and adolescents. Am J Clin Nutr. 1997;66:232-238.
20. Tanner JM, Whitehouse RH, Cameron N, Marshall WA, Healy MJR, Goldstein H. Assessment of skeletal maturity and prediction of adult height (TW2 method), 2nd edition. London: Academic Press, 1983.
21. Hokken-Koelega ACS, Hackeng WHL, Stijnen T, Wit JM, de Muinck Keizer-Schrama SMPF, Drop SLS. Twenty-four hour plasma growth hormone profiles, urinary GH excretion and plasma insulin-like growth factor-I and -II levels in prepubertal children with chronic renal insufficiency and severe growth retardation. J Clin Endocrinol Metab. 1990; 71:688-695.
22. Martin TJ, Ng KW, Nicholson GC. Cell biology of bone. Baillières Clin Endocrinol Metab. 1988; 2:1-29.
23. Lukert BP, Raisz LG. Glucocorticoid-induced osteoporosis: Pathogenesis and management. Ann Intern Med. 1990; 112:352-364.
24. Adinoft AD, Hollister JR. Steroid induced fractures and hone loss in patients with asthma. N Engl Med. 1983; 309:265-268.
25. Soliman AT, Hassan AEHI, Aref MK, Hintz RL, Rosenfeld RG, Rogol AD. Serum insulin-like growth factors in children with protein-energy malnutrition before and after nutritional rehabilitation. Pediatr Res. 1986; 20:1122-1130.
26. Crowley S, Hindmarsh PC, Matthews DR, Brook GD. Growth and the growth hormone axis in prepubertal children with asthma. J Pediatr. 1995; 126:297-303.
27. Hauspie R, Crowley S, Alexander F. Maturational delay and temporal growth retardation in asthmatic boys. J Allergy Clin Immunol. 1977; 59:200-206.
28. Martin AJ, Landau LI, Phelan PD. The effect on growth of childhood asthma. Acta Paediatr Scand. 1981; 70:683-688.
29. Finkelstein JS, Neer RM, Biller BMK, Crawford JD, Klibanski A. Osteopenia in men with a history of delayed puberty. N Engl J Med. 1992; 326:600-604.
30. Ott SM. Attainment of peak bone mass. (Editorial). J Clin Endocrinol Metab. 1990; 71:1082A-C.
31. Hansen MA, Overgaard K, Riis BJ, Christiansen C. Role of peak bone mass and bone loss in postmenopausal osteoporosis: 12 year study. Br Med J. 1991; 303:961-964.
32. Hanania NA, Chapman KR, Sturtridge WC, Szalai JP, Kesten S. Dose-related decrease in bone density among asthmatic patients treated with inhaled corticosteroids. J Allergy Clin Immunol. 1995; 96:571-579.
33. Boulet LP, Giguere MC, Milot J, Brown J. Effects of long-term use of high-dose inhaled steroids on bone density and calcium metabolism. J Allergy Clin Immunol. 1994; 94:796-803.
34. Birkebaek NH, Esberg G, Andersen K, Wolthers O, Hassager C. Bone and collagen turnover during treatment with inhaled dry powder budesonide and beclomethasone dipropionate. Arch Dis Child. 1995; 73:524-527.
35. Epstein S. Serum and urinary markers of bone remodelling: Assessment of bone turnover. J Clin Endocrinol Metab. 1988; 9:437-445.
36. Parfitt AM, Simon LS, Villanueva AR, Krane SM. Procollagen type 1 carboxy-terminal extension peptide in serum as a marker of collagen biosynthesis in bone: Correlation with iliac bone formation rates and comparison with total alkaline phosphatase. J Bone Miner Res. 1987; 2:427-436.
37. Kerstjens HAM, Postma DS, van Doormaal JJ, van Zanten AK, Brand PLP, Dekhuijzen PNR, Koeter GH. Effects of short term and long term treatment with inhaled corticosteroids on bone metabolism in patients with airway obstruction. Thorax. 1994; 49: 652-656.