-
2
-
-
0032692344
-
Antinociceptive and anti-inflammatory effects of Tanacetum parthenium L. extract in mice and rats
-
Jain N.K., Kulkarni S.K. Antinociceptive and anti-inflammatory effects of Tanacetum parthenium L. extract in mice and rats. J. Ethnopharmacol. 68:1999;251-259.
-
(1999)
J. Ethnopharmacol.
, vol.68
, pp. 251-259
-
-
Jain, N.K.1
Kulkarni, S.K.2
-
3
-
-
0343765810
-
Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF-kappaB
-
Bork P.M., Schmitz M.L., Kuhnt M., Escher C., Heinrich M. Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF-kappaB. FEBS Lett. 402:1997;85-90.
-
(1997)
FEBS Lett.
, vol.402
, pp. 85-90
-
-
Bork, P.M.1
Schmitz, M.L.2
Kuhnt, M.3
Escher, C.4
Heinrich, M.5
-
4
-
-
0030823162
-
Helenalin, an anti-inflammatory sesquiterpene lactone from Arnica, selectively inhibits transcription factor NF-κB
-
Lyβ G., Schmidt T.J., Merfort I., Pahl H.L. Helenalin, an anti-inflammatory sesquiterpene lactone from Arnica, selectively inhibits transcription factor NF-κB. Biol. Chem. 378:1997;951-961.
-
(1997)
Biol. Chem.
, vol.378
, pp. 951-961
-
-
Lyß, G.1
Schmidt, T.J.2
Merfort, I.3
Pahl, H.L.4
-
5
-
-
0038809627
-
Inhibition of transcription factor NF-κB by sesquiterpene lactones: A proposed molecular mechanism of action
-
Rüngeler P., Castro V., Mora G., Gören N., Vischnewski W., Pahl H.L., Merfort I., Schmidt T.J. Inhibition of transcription factor NF-κB by sesquiterpene lactones: a proposed molecular mechanism of action. Bioorg. Med. Chem. 7:1999;2343-2352.
-
(1999)
Bioorg. Med. Chem.
, vol.7
, pp. 2343-2352
-
-
Rüngeler, P.1
Castro, V.2
Mora, G.3
Gören, N.4
Vischnewski, W.5
Pahl, H.L.6
Merfort, I.7
Schmidt, T.J.8
-
6
-
-
0033610023
-
Sesquiterpene lactones inhibit inducible nitric oxide synthase gene expression in cultured rat aortic smooth muscle cells
-
Wong H.R., Menendez I.Y. Sesquiterpene lactones inhibit inducible nitric oxide synthase gene expression in cultured rat aortic smooth muscle cells. Biochem. Biophys. Res. Cummun. 262:1999;375-380.
-
(1999)
Biochem. Biophys. Res. Cummun.
, vol.262
, pp. 375-380
-
-
Wong, H.R.1
Menendez, I.Y.2
-
8
-
-
0035955729
-
Cysteine 38 in p65/NF-κB plays a crucial role in DNA binding inhibition by sesquiterpene lactones
-
García-Piñeres A.J., Castro V., Mora G., Schmidt T.J., Strunck E., Pahl H.L., Merfort I. Cysteine 38 in p65/NF-κB plays a crucial role in DNA binding inhibition by sesquiterpene lactones. J. Biol. Chem. 276:2001;39713-39720.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39713-39720
-
-
García-Piñeres, A.J.1
Castro, V.2
Mora, G.3
Schmidt, T.J.4
Strunck, E.5
Pahl, H.L.6
Merfort, I.7
-
9
-
-
0035324446
-
Role of transcription factor NFAT in the immune response
-
Kuklina E.M., Shirshev S.V. Role of transcription factor NFAT in the immune response. Biochemistry (Mosc.). 66:2001;467-475.
-
(2001)
Biochemistry (Mosc.)
, vol.66
, pp. 467-475
-
-
Kuklina, E.M.1
Shirshev, S.V.2
-
10
-
-
0031757934
-
Nuclear factor kappa B: Important transcription factor and therapeutic target
-
Lee J.-I., Burckart G.J. Nuclear factor kappa B: important transcription factor and therapeutic target. J. Clin. Pharmacol. 38:1998;981-993.
-
(1998)
J. Clin. Pharmacol.
, vol.38
, pp. 981-993
-
-
Lee, J.-I.1
Burckart, G.J.2
-
11
-
-
0030942048
-
Lymphocyte activation in health and disease
-
Berridge M.J. Lymphocyte activation in health and disease. Crit. Rev. Immunol. 17:1997;155-178.
-
(1997)
Crit. Rev. Immunol.
, vol.17
, pp. 155-178
-
-
Berridge, M.J.1
-
13
-
-
0035400612
-
Involvement of nuclear factor-kappa B (NF-κB) activation in mitogen-induced lymphocyte proliferation: Inhibitory effects of lymphoproliferation by salicylates acting as NF-κB inhibitors
-
Cavallini L., Francesconi M.A., Zoccarato F., Alexandre A. Involvement of nuclear factor-kappa B (NF-κB) activation in mitogen-induced lymphocyte proliferation: inhibitory effects of lymphoproliferation by salicylates acting as NF-κB inhibitors. Biochem. Pharmacol. 62:2001;141-147.
-
(2001)
Biochem. Pharmacol.
, vol.62
, pp. 141-147
-
-
Cavallini, L.1
Francesconi, M.A.2
Zoccarato, F.3
Alexandre, A.4
-
14
-
-
0036273516
-
Studies on the anti-inflammatory activity of phytopharmaceuticals prepared from Arnica flowers
-
Klaas C.A., Wagner G., Laufer S., Sosa S., Della Loggia R., Bomme U., Pahl H.L., Merfort I. Studies on the anti-inflammatory activity of phytopharmaceuticals prepared from Arnica flowers. Planta Med. 68:2002;385-391.
-
(2002)
Planta Med.
, vol.68
, pp. 385-391
-
-
Klaas, C.A.1
Wagner, G.2
Laufer, S.3
Sosa, S.4
Della Loggia, R.5
Bomme, U.6
Pahl, H.L.7
Merfort, I.8
-
15
-
-
0035885243
-
Inhibition of inflammatory cytokine production and lymphocyte proliferation by structurally different sesquiterpene lactones correlates with their effect on activation of NF-κB
-
Koch E., Klaas C.A., Rüngeler P., Castro V., Mora G., Vischnewski W., Merfort I. Inhibition of inflammatory cytokine production and lymphocyte proliferation by structurally different sesquiterpene lactones correlates with their effect on activation of NF-κB. Biochem. Pharmacol. 62:2001;795-801.
-
(2001)
Biochem. Pharmacol.
, vol.62
, pp. 795-801
-
-
Koch, E.1
Klaas, C.A.2
Rüngeler, P.3
Castro, V.4
Mora, G.5
Vischnewski, W.6
Merfort, I.7
-
16
-
-
0033949765
-
Sesquiterpene lactones are potent inhibitors of interleukin 8 gene expression in cultured human respiratory epithelium
-
Mazor R.L., Menendez I.Y., Ryan M.A., Fiedler M.A., Wong H.R. Sesquiterpene lactones are potent inhibitors of interleukin 8 gene expression in cultured human respiratory epithelium. Cytokine. 12:2000;239-245.
-
(2000)
Cytokine
, vol.12
, pp. 239-245
-
-
Mazor, R.L.1
Menendez, I.Y.2
Ryan, M.A.3
Fiedler, M.A.4
Wong, H.R.5
-
17
-
-
0035920223
-
Targeting of p300 to the interleukin-2 promoter via CREB-Rel cross-talk during mitogen and oncogene molecular signaling in activated T-Cells
-
Butscher W.G., Haggerty C.M., Chaudhry S., Gardner K. Targeting of p300 to the interleukin-2 promoter via CREB-Rel cross-talk during mitogen and oncogene molecular signaling in activated T-Cells. J. Biol. Chem. 276:2001;27647-27656.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27647-27656
-
-
Butscher, W.G.1
Haggerty, C.M.2
Chaudhry, S.3
Gardner, K.4
-
18
-
-
0035861992
-
Kinetic and mechanistic analysis of the RNA polymerase II transcription reaction at the human interleukin-2 promoter
-
Ferguson H.A., Kugel J.F., Goodrich J.A. Kinetic and mechanistic analysis of the RNA polymerase II transcription reaction at the human interleukin-2 promoter. J. Mol. Biol. 314:2001;993-1006.
-
(2001)
J. Mol. Biol.
, vol.314
, pp. 993-1006
-
-
Ferguson, H.A.1
Kugel, J.F.2
Goodrich, J.A.3
-
19
-
-
0029928417
-
The expanding universe of T cell subsets: Th1, Th2 and more
-
Mosmann T.R., Sad S. The expanding universe of T cell subsets: Th1, Th2 and more. Immunol. Today. 3:1996;138-146.
-
(1996)
Immunol. Today
, vol.3
, pp. 138-146
-
-
Mosmann, T.R.1
Sad, S.2
-
21
-
-
0031857341
-
T cells and T-cell cytokine transcripts in the synovial membrane in patients with osteoarthritis
-
Sakkas L.I., Scanzello C., Johanson N., Burkholder J., Mitra A., Salgame P., Katsetos C.D., Plastsoucas C.D. T cells and T-cell cytokine transcripts in the synovial membrane in patients with osteoarthritis. Clin. Diagn. Lab. Immunol. 5:1998;430-437.
-
(1998)
Clin. Diagn. Lab. Immunol.
, vol.5
, pp. 430-437
-
-
Sakkas, L.I.1
Scanzello, C.2
Johanson, N.3
Burkholder, J.4
Mitra, A.5
Salgame, P.6
Katsetos, C.D.7
Plastsoucas, C.D.8
-
23
-
-
0029166374
-
Transcriptional regulation of the gene encoding the human C-type lectin leukocyte receptor AIM/CD69 and functional characterization of its tumor necrosis factor-α-responsive elements
-
López-Cabrera M., Muñoz E., Valle Blázquez M., Ursa M.A., Santis A.G., Sánchez-Madrid F. Transcriptional regulation of the gene encoding the human C-type lectin leukocyte receptor AIM/CD69 and functional characterization of its tumor necrosis factor-α-responsive elements. J. Biol. Chem. 270:1995;21545-21551.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21545-21551
-
-
López-Cabrera, M.1
Muñoz, E.2
Valle Blázquez, M.3
Ursa, M.A.4
Santis, A.G.5
Sánchez-Madrid, F.6
-
24
-
-
0030904120
-
Helenanolide-type sesquiterpene lactones. III. Rates and stereochemistry in the reaction of helenalin and related helenanolides with sulfhydryl containing biomolecules
-
Schmidt T.J. Helenanolide-type sesquiterpene lactones. III. Rates and stereochemistry in the reaction of helenalin and related helenanolides with sulfhydryl containing biomolecules. Bioorg. Med. Chem. 5:1997;645-653.
-
(1997)
Bioorg. Med. Chem.
, vol.5
, pp. 645-653
-
-
Schmidt, T.J.1
-
25
-
-
0032575870
-
Antimycobacterial evaluation of germacranolides
-
Fischer N.H., Lu T., Cantrell C.L., Castaneda-Acosta J., Quijano L., Franzblau S.G. Antimycobacterial evaluation of germacranolides. Phytochemistry. 49:1998;559-564.
-
(1998)
Phytochemistry
, vol.49
, pp. 559-564
-
-
Fischer, N.H.1
Lu, T.2
Cantrell, C.L.3
Castaneda-Acosta, J.4
Quijano, L.5
Franzblau, S.G.6
-
26
-
-
0343819990
-
Study of sesquiterpene lactones From Milleria quinqueflora on their anti-inflammatory activity using the transcription factor NF-kappa B as molecular target
-
Castro V., Rüngeler P., Murillo R., Hernandez E., Mora G., Pahl H.L., Merfort I. Study of sesquiterpene lactones From Milleria quinqueflora on their anti-inflammatory activity using the transcription factor NF-kappa B as molecular target. Phytochemistry. 53:2000;257-263.
-
(2000)
Phytochemistry
, vol.53
, pp. 257-263
-
-
Castro, V.1
Rüngeler, P.2
Murillo, R.3
Hernandez, E.4
Mora, G.5
Pahl, H.L.6
Merfort, I.7
-
27
-
-
0032946787
-
15-Hydroxyeremantholide and derivatives from Eremanthus arboreus
-
Vischnewski W., Skrochy C.A., Nasi A.M., Lopes C., Herz W. 15-Hydroxyeremantholide and derivatives from Eremanthus arboreus. Phytochemistry. 50:1999;317-320.
-
(1999)
Phytochemistry
, vol.50
, pp. 317-320
-
-
Vischnewski, W.1
Skrochy, C.A.2
Nasi, A.M.3
Lopes, C.4
Herz, W.5
-
28
-
-
0021361499
-
Helenalin-und 11α13-dihydrohelenalinester aus Blüten von Arnica montana
-
Willuhn G., Röttger P.M., Wendisch D. Helenalin-und 11α13-dihydrohelenalinester aus Blüten von Arnica montana. Planta Med. 50:1984;35-37.
-
(1984)
Planta Med.
, vol.50
, pp. 35-37
-
-
Willuhn, G.1
Röttger, P.M.2
Wendisch, D.3
-
29
-
-
0026556554
-
Death cell discrimination with 7-amino-actinomycin D in combination with dual color immunofluorescence in single laser cytometry
-
Schmid I., Krall W.J., Uittenbogaard C.H. Death cell discrimination with 7-amino-actinomycin D in combination with dual color immunofluorescence in single laser cytometry. Cytometry. 13:1992;204-208.
-
(1992)
Cytometry
, vol.13
, pp. 204-208
-
-
Schmid, I.1
Krall, W.J.2
Uittenbogaard, C.H.3
-
30
-
-
0029043888
-
A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V
-
Vermes I., Haanen C., Steffens-Nakken H., Reutelingsperger C. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J. Immunol. Methods. 184:1995;39-51.
-
(1995)
J. Immunol. Methods
, vol.184
, pp. 39-51
-
-
Vermes, I.1
Haanen, C.2
Steffens-Nakken, H.3
Reutelingsperger, C.4
-
31
-
-
0033118516
-
Kinetics of intracytoplasmic Th1 and Th2 cytokine production assessed by flow cytometry following in vitro activation of peripheral blood mononuclear cells
-
Rostaing L., Tkaczuk J., Durand M., Peres C., Durand D., de Preval C., Ohayon E., Abbal M. Kinetics of intracytoplasmic Th1 and Th2 cytokine production assessed by flow cytometry following in vitro activation of peripheral blood mononuclear cells. Cytometry. 35:1999;318-328.
-
(1999)
Cytometry
, vol.35
, pp. 318-328
-
-
Rostaing, L.1
Tkaczuk, J.2
Durand, M.3
Peres, C.4
Durand, D.5
De Preval, C.6
Ohayon, E.7
Abbal, M.8
-
33
-
-
0001112989
-
The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-κB by directly targeting p65
-
Lyβ G., Knorre A., Schmidt T.J., Pahl H.L., Merfort I. The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-κB by directly targeting p65. J. Biol. Chem. 273:1998;33508-33516.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33508-33516
-
-
Lyß, G.1
Knorre, A.2
Schmidt, T.J.3
Pahl, H.L.4
Merfort, I.5
-
35
-
-
0036909586
-
The anti-inflammatory sesquiterpene lactone parthenolide suppresses IL-4 gene expression in peripheral blood T
-
Li-Weber M., Giaisi M., Treiber M.K., Krammer P.H. The anti-inflammatory sesquiterpene lactone parthenolide suppresses IL-4 gene expression in peripheral blood T. Eur. J. Immunol. 32:2002;3587-3597.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 3587-3597
-
-
Li-Weber, M.1
Giaisi, M.2
Treiber, M.K.3
Krammer, P.H.4
-
36
-
-
0032696632
-
Toxic activities of sesquiterpene lactones: Structural and biochemical aspects
-
Schmidt T.J. Toxic activities of sesquiterpene lactones: structural and biochemical aspects. Curr. Org. Chem. 3:1999;577-608.
-
(1999)
Curr. Org. Chem.
, vol.3
, pp. 577-608
-
-
Schmidt, T.J.1
-
37
-
-
0026007123
-
CD69 in resting and activated T lymphocytes. Its association with a GTP binding protein and biochemical requirements for its expression
-
Risso A., Smilovich D., Capra M.C., Baldissarro I., Yan G., Bargellesi A., Cosulich M.E. CD69 in resting and activated T lymphocytes. Its association with a GTP binding protein and biochemical requirements for its expression. J. Immunol. 146:1991;4105-4114.
-
(1991)
J. Immunol.
, vol.146
, pp. 4105-4114
-
-
Risso, A.1
Smilovich, D.2
Capra, M.C.3
Baldissarro, I.4
Yan, G.5
Bargellesi, A.6
Cosulich, M.E.7
-
38
-
-
0033120071
-
Similarities and differences between human and murine TNF promoters in their response to lipopolysaccharide
-
Kuprash D.V., Udalova I.A., Turetskaya R.L., Kwiatkowski D., Rice N.R., Nedospasov S.A. Similarities and differences between human and murine TNF promoters in their response to lipopolysaccharide. J. Immunol. 162:1999;4045-4052.
-
(1999)
J. Immunol.
, vol.162
, pp. 4045-4052
-
-
Kuprash, D.V.1
Udalova, I.A.2
Turetskaya, R.L.3
Kwiatkowski, D.4
Rice, N.R.5
Nedospasov, S.A.6
-
39
-
-
0035940963
-
Interaction of AP-1 with a cluster of NF-κB binding elements in the human TNF promoter region
-
Udalova I.A., Kwiatkowski D. Interaction of AP-1 with a cluster of NF-κB binding elements in the human TNF promoter region. Biochem. Biophys. Res. Cummun. 289:2001;25-33.
-
(2001)
Biochem. Biophys. Res. Cummun.
, vol.289
, pp. 25-33
-
-
Udalova, I.A.1
Kwiatkowski, D.2
-
41
-
-
0034902498
-
The influence of glutathione and cysteine levels on the cytotoxicity of helenanolide type sesquiterpene lactones against KB cells
-
Heilmann J., Wasescha M.R., Schmidt T.J. The influence of glutathione and cysteine levels on the cytotoxicity of helenanolide type sesquiterpene lactones against KB cells. Bioorg. Med. Chem. 9:2001;2189-2194.
-
(2001)
Bioorg. Med. Chem.
, vol.9
, pp. 2189-2194
-
-
Heilmann, J.1
Wasescha, M.R.2
Schmidt, T.J.3
-
42
-
-
0030730195
-
Feverfew (Tanacetum parthenium) as a prophylactic treatment for migraine: A double-blind placebo-controlled study
-
Palevitch D., Earon G., Carasso R. Feverfew (Tanacetum parthenium) as a prophylactic treatment for migraine: a double-blind placebo-controlled study. Phytother. Res. 11:1997;508-511.
-
(1997)
Phytother. Res.
, vol.11
, pp. 508-511
-
-
Palevitch, D.1
Earon, G.2
Carasso, R.3
|