Immunological characterization of A2B adenosine receptors in human mast cells

Drug Development Research

Volumn 58, Issue 4, 2003, Pages 461-471

  Feoktistov, Igor ^a,b   Goldstein, Anna ^a   Sheller, James R ^a   Schwartz, Lawrence B ^c   Biaggioni, Italo ^a,b  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Asthma; Bronchoalveolar lavage; Receptors, purinergic P1

Indexed keywords

ADENOSINE A2B RECEPTOR; ANTIBODY; HEMAGGLUTININ; HYBRID PROTEIN; MONOCLONAL ANTIBODY; TRYPTASE; TRYPTASE MONOCLONAL ANTIBODY; TUNICAMYCIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBODY SPECIFICITY; ASTHMA; CARBOXY TERMINAL SEQUENCE; CELL ACTIVATION; CELL LINE; CONFERENCE PAPER; CONTROLLED STUDY; DEGLYCOSYLATION; GLYCOSYLATION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; IMMUNOREACTIVITY; LUNG LAVAGE; MAST CELL; MOLECULAR WEIGHT; NONHUMAN; WESTERN BLOTTING;

EID: 0038050308     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.10180     Document Type: Conference Paper

References (40)

1. Altschul SF, Gish W, Miller W, Myers W, Lipman DJ. 1990. Basic local alignment search tool. J Mol Biol 215:403-410.
2. 2B receptor. Mol Pharmacol 52:846-860.
3. Backstrom JR, Westphal RS, Canton H, Sanders-Bush E. 1995. Identification of rat serotonin 5-HT2C receptors as glycoproteins containing N-linked oligosaccharides. Brain Res 33:311-318.
4. Biaggioni I, Paul S, Puckett A, Arzubiaga C. 1991. Caffeine and theophylline as adenosine receptor antagonists in humans. J Pharmacol Exp Ther 258:588-593.
5. Church MK, Holgate ST. 1986. Adenosine and asthma. Trends Pharmacol Sci 7:49-50.
6. Church MK, Hughes PJ, Vardey CJ. 1986. Studies on the receptor mediating cyclic AMP-independent enhancement by adenosine of IgE-dependent mediator release from rat mast cells. Br J Pharmacol 87:233-242.
7. 2B receptor. Nature 407:747-750.
8. Cushley MJ, Tattersfield AE, Holgate ST. 1984. Adenosine-induced bronchoconstriction in asthma. Am Rev Respir Dis 129:380-384.
9. Dixon KD, Gubitz AK, Sirinathsinghji DJS, Richardson PJ, Freeman TC. 1996. Tissue distribution of adenosine receptor mRNAs in the rat. Br J Pharmacol 118:1461-1468.
10. 2B receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma. J Clin Invest 96:1979-1986.
11. 2B receptors. Pharmacol Rev 49:381-402.
12. 2B receptors - a novel therapeutic target in asthma? Trends Pharmacol Sci 19:148-153.
13. (2B) receptor antagonist 3-isobutyl-8-pyrrolidinoxanthine (IPDX). Biochem Pharmacol 62:1163-1173.
14. 2B-selective adenosine receptor antagonists. J Med Chem 45:1500-1510.
15. Hebert TE, Bouvier M. 1998. Structural and functional aspects of G protein-coupled receptor oligomerization. Biochem Cell Biol 76:1-11.
16. TC types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and anti-chymase antibodies. J Histochem Cytochem 37:1509-1515.
17. Janin J. 1979. Surface and inside volumes in globular proteins. Nature 277:491-492.
18. (2B) adenosine receptors. J Med Chem 43:1165-1172.
19. Klotz KN, Hessling J, Hegler J, Owman C, Kull B, Fredholm BB, Lohse MJ. 1998. Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells. Naunyn-Schmiedebergs Arch Pharmacol 357:1-9.
20. q in human embryonic kidney 293 cells and HMC-1 mast cells. Mol Pharmacol 56:705-713.
21. Mahoney WC, Duksin D. 1979. Biological activities of the two major components of tunicamycin. J Biol Chem 254:6572-6576.
22. Maley F, Trimble RB, Tarentino AL, Plummer TH Jr. 1989. Characterization of glycoproteins and their associated oligosaccharides through the use of endoglycosidases. Anal Biochem 180:195-204.
23. Marquardt DL, Parker CW, Sullivan TJ. 1978. Potentiation of mast cell mediator release by adenosine. J Immunol 120:871-878.
24. Marquardt DL, Walker LL, Heinemann S. 1994. Cloning of two adenosine receptor subtypes from mouse bone marrow-derived mast cells. J Immunol 152:4508-4515.
25. 2B adenosine receptor trafficking. Biochemistry 39:12828-12836.
26. Nesbitt SA, Horton MA. 1992. A nonradioactive biochemical characterization of membrane proteins using enhanced chemiluminescence. Anal Biochem 206:267-272.
27. Parker JM, Guo D, Hodges RS. 1986. New hydrophilicity scale derived from high-performance liquid chromatography peptide retention data: correlation of predicted surface residues with antigenicity and X-ray-derived accessible sites. Biochemistry 25:5425-5432.
28. Peachell PT, Lichtenstein LM, Schleimer RP. 1991. Differential regulation of human basophil and lung mast cell function by adenosine. J Pharmacol Exp Ther 256:717-726.
29. Phillips GD, Scott VL, Richards R, Holgate ST. 1989. Effect of nedocromil sodium and sodium cromoglycate against bronchoconstriction induced by inhaled adenosine 5′-monophosphate. Eur Respir J 2:210-217.
30. 2B receptor from human brain. Biochem Biophys Res Commun 187:86-93.
31. Polosa R, Ng WH, Crimi N, Vanceri C, Holgate ST, Church MK, Mistretta A. 1995. Release of mast cell-derived mediators after endobronchial adenosine challenge in asthma. Am J Resp Crit Care Med 151:624-629.
32. 2B receptor. Mol Pharmacol 47:1126-1132.
33. Rafferty P, Beasley CR, Holgate ST 1987. The contribution of histamine to immediate bronchoconstriction provoked by inhaled allergen and adenosine-5′monophosphate in atopic asthma. Am Rev Respir Dis 136:369-373.
34. Rall TW. 1982. Evolution of the mechanisms of action of methylxanthines: from calcium mobilizers to antagonists of adenosine receptors. Pharmacologist 24:277-287.
35. 3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells. J Biol Chem 268:16887-16890.
36. Schwartz LB. 1994. Tryptase: a clinical indicator of mast cell-dependent events. Allergy Proc 15:119-123.
37. 2 adenosine receptor subtype. Mol Endocrinol 6:384-393.
38. 2 adenosine receptors. Eur J Pharmacol 117:25-33.
39. Welling GW, Weijer WJ, van der Zee R, Welling-Wester S. 1985. Prediction of sequential antigenic regions in proteins. FEBS Lett 188:215-218.
40. 3 adenosine receptor. Proc Natl Acad Sci 89:7432-7436.