Correlation of tumor oxygen dynamics with radiation response of the dunning prostate R3327-HI tumor

Radiation Research

Volumn 159, Issue 5, 2003, Pages 621-631

  Zhao, Dawen ^a   Constantinescu, Anca ^a   Chang, Cheng Hui ^a   Hahn, Eric W ^a   Mason, Ralph P ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEXAFLUOROBENZENE; HOE 33342; OXYGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER RADIOTHERAPY; CELL DIFFERENTIATION; CONTROLLED STUDY; CORRELATION ANALYSIS; ECHO PLANAR IMAGING RELAXOMETRY; EVALUATION; HISTOPATHOLOGY; HYPOTHESIS; HYPOXIA; IMMUNOHISTOCHEMISTRY; IONIZING RADIATION; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXYGEN TENSION; OXYGEN TISSUE LEVEL; PHOTON; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROSTATE TUMOR; RADIATION DOSE; RADIATION RESPONSE; RAT; STATISTICAL SIGNIFICANCE; TISSUE PERFUSION; TUMOR VOLUME;

ANIMALS; MALE; OXIMETRY; OXYGEN; PROSTATIC NEOPLASMS; RADIATION TOLERANCE; RATS;

EID: 0037964264     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/0033-7587(2003)159[0621:COTODW]2.0.CO;2     Document Type: Article

References (55)

1. M. Höckel, K. Schlenger, B. Aral, M. Mitze, U. Schäffer and P. Vaupel, Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res. 56, 4509-4515 (1996).
2. A. W. Fyles, M. Milosevic, R. Wong, M.-C. Kavanagh, M. Pintile, A. Sun, W. Chapman, W. Levin, L. Manchul and R. P. Hill, Oxygenation predicts radiation response and survival in patients with cervix cancer. Radiother. Oncol. 48, 149-156 (1998).
3. J. Overgaard and M. R. Horsman, Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers. Semin. Radiat. Oncol. 6, 10-21 (1996).
4. J. M. Brown, The hypoxic cell: A target for selective cancer therapy. Cancer Res. 59, 5863-5870 (1999).
5. M. Höckel and P. Vaupel, Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects. J. Natl. Cancer Inst. 93, 266-276 (2001).
6. P. Vaupel, D. K. Kelleher and O. Thews, Modulation of tumor oxygenation. Int. J. Radiat. Oncol. Biol. Phys. 42, 843-848 (1998).
7. A. Rojas, V. K. Hirst, A. S. Calvert and H. J. Johns, Carbogen and nicotinamide as radiosensitizers in a murine mammary carcinoma using conventional and accelerated radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 3, 357-365 (1996).
8. J. H. A. M. Kaanders, L. A. M. Pop, H. A. M. Marres, I. Bruaset, F. J. A. van den Hoogen, M. A. W. Merkx and A. J. van der Kogel, ARCON: Experience in 215 patients with advanced head-and neck cancer. Int. J. Radiat. Oncol. Biol. Phys. 52, 769-778 (2002).
9. P. Rubin, J. Hanley, H. M. Keys, V. Marcial and L. Brady, Carbogen breathing during radiation therapy: The Radiation Therapy Oncology Group study. Int. J. Radiat. Oncol. Biol. Phys. 5, 1963-1970 (1979).
10. D. M. Brizel, G. S. Sibly, L. R. Prosnitz, R. L. Scher and M. W. Dewhirst, Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck. Int. J. Radiat. Oncol. Biol. Phys. 38, 285-289 (1997).
11. M. Nordsmark, M. Overgaard and J. Overgaard, Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of head and neck. Radiother. Oncol. 41, 31-39 (1996).
12. 2 histography in patients with advanced head and neck cancer. Radiother. Oncol. 57, 31-37 (2000).
13. 2 and radiosensitivity of tumors by Fluosol and carbogen. Cancer Res. 47, 442-446 (1987).
14. J. Bussink, J. H. A. M. Kaanders, A. M. Strik and A. J. van der Kogel, Effects of nicotinamide and carbogen on oxygenation in human tumor xenografts measured with luminescence based fiberoptic probes. Radiother. Oncol. 57, 21-30 (2000).
15. 2 measurements by electron paramagnetic resonance oximetry. Radiat. Res. 150, 549-556 (1998).
16. S. P. Robinson, F. A. Howe, L. M. Rodrigues, M. Stubbs and J. R. Griffiths, Magnetic resonance imaging techniques for monitoring changes in tumor oxygenation and blood flow. Semin. Radiat. Oncol. 8, 198-207 (1998).
17. R. P. Mason, A. Constantinescu, S. Hunjan, D. Le, E. W. Hahn, P. P. Antich, C. Blum and P. Peschke, Regional tumor oxygenation and measurement of dynamic changes. Radiat. Res. 152, 239-249 (1999).
18. S. Hunjan, D. Zhao, A. Constantinescu, E. W. Hahn, P. P. Antich and R. P. Mason, Tumor oximetry: Demonstration of an enhanced dynamic mapping procedure using fluorine-19 echo planar magnetic resonance imaging in the Dunning prostate R3327-AT1 rat tumor. Int. J. Radiat. Oncol. Biol. Phys. 49, 1097-1108 (2001).
19. D. Zhao, A. Constantinescu, E. W. Hahn and R. P. Mason, Tumor oxygen dynamics with respect to growth and respiratory challenge: Investigation of the Dunning prostate R3327-HI tumor. Radiat. Res. 156, 510-520 (2001).
20. D. Zhao, A. Constantinescu, E. W. Hahn and R. P. Mason, Differential oxygen dynamics in two diverse Dunning prostate R3327 rat tumor sublines (MAT-Lu and HI) with respect to growth and respiratory challenge. Int. J. Radiat. Oncol. Biol. Phys. 53, 744-756 (2002).
21. J. Isaacs, W. Isaacs, W. Feitz and J. Scheres, Establishment and characterization of 7 Dunning prostate cancer cell lines and their use in developing methods for predicting metastatic ability of prostate cancer. Prostate 9, 261-281 (1986).
22. P. Peschke, E. W. Hahn, F. Wenz, F. Lohr, F. Braunschweig, G. Wolber, I. Zuna and M. Wannenmacher, Differential sensitivity of three sublines of the rat Dunning prostate tumor system R3327 to radiation and/or local tumor hyperthermia. Radiat. Res. 150, 423-430 (1998).
23. E. W. Hahn, P. Peschke, R. P. Mason, E. E. Babcock and P. P. Antich, Isolated tumor growth in a surgically formed skin pedicle in the rat: A new tumor model for NMR studies. Magn. Reson. Imaging 11, 1007-1017 (1993).
24. N. Weidner, J. Folkman, F. Pozza, P. Bevilacqua, E. N. Allred and D. H. Moore, Tumor angiogenesis: A new significant and independent prognostic indicator in early-stage breast carcinoma. J. Natl. Cancer Inst. 84, 1875-1887 (1992).
25. L. H. Gray, A. Conger, M. Ebert, S. Hornsey and O. Scott, The concentration of oxygen dissolved in tissues at time of irradiation as a factor in radiotherapy. Br. J. Radiol. 26, 638-648 (1953).
26. G. Stuben, M. Stuschke, K. Knuhmann, M. R. Horsman and H. Sack, The effect of combined nicotinamide and carbogen treatments in human tumor xenografts: Oxygenation and tumor control studies. Radiother. Oncol. 48, 143-148 (1998).
27. P. Okunieff, M. Höckel, E. P. Dunphy and P. W. Vaupel, Oxygen tension distributions are sufficient to explain the local response of human breast tumors treated with radiation alone. Int. J. Radiat. Oncol. Biol. Phys. 26, 631-636 (1993).
28. B. Movsas, J. Chapman, E. Horwitz, W. Pinover, R. Greenberg, A. Hanlon, R. Iyer and G. Hanks, Hypoxic regions exist in human prostate carcinoma. Urology 53, 11-18 (1999).
29. 2 distribution and bioreductive enzymes in human malignant brain tumors. Int. J. Radiat. Oncol. Biol. Phys. 29, 427-431 (1994).
30. C. Aquino-Parsons, A. Green and A. I. Minchinton, Oxygen tension in primary gynaecological tumours: The influence of carbon dioxide concentration. Radiother. Oncol. 57, 45-51 (2000).
31. 2 in tumors in response to carbogen breathing. Int. J. Radiat. Oncol. Biol. Phys. 42, 855-859 (1998).
32. B. J. P. van der Sanden, A. Heerschap, L. Hoofd, A. W. Simonetti, K. Nicolay, A. van der Toorn, W. N. M. Colier and A. J. van der Kogel, Effect of carbogen breathing on the physiological profile of human glioma xenografts. Magn. Reson. Med. 42, 490-499 (1999).
33. H. D. Suit, N. Marshall and D. Woerner, Oxygen, oxygen plus carbon dioxide, and radiation therapy of a mouse mammary carcinoma. Cancer 30, 1154-1158 (1972).
34. O. Thews, D. K. Kelleher and P. Vaupel, Dynamics of tumor oxygenation and red blood cell flux in response to inspiratory hyperoxia combined with different levels of inspiratory hypercapnia. Radiother. Oncol. 62, 77-85 (2002).
35. 2 histography. Br. J. Cancer 66, 919-924 (1992).
36. C. Thorndyke, B. Meeker, G. Thomas, W. Laky, M. McPhee and J. Chapman, The radiation sensitivities of R3327-H and -AT1 rat prostate adenocarcinomas. J. Urol. 134, 191-198 (1985).
37. J. Bussink, J. H. A. M. Kaanders, A. M. Strik, B. Vojnovic and A. J. van der Kogel, Optical sensor-based oxygen tension measurements correspond with hypoxia marker binding in three human tumor xenograft lines. Radiat. Res. 154, 547-555 (2000).
38. B. Gallez, B. F. Jordan, C. Baudelet and P. D. Mission, Pharmacological modification of the partial pressure of oxygen in the murine tumors: Evaluation using in vivo EPR oximetry. Magn. Reson. Med. 42, 627-630 (1999).
39. 2 measured by EPR oximetry in human tumor xenografts. Radiat. Res. 155, 466-473 (2001).
40. 19F PBSR EPI of hexafluorobenzene. Magn. Reson. Imaging 15, 971-981 (1997).
41. 19F NMR indicator of tumor oxygenation. NMR Biomed. 9, 125-134 (1996).
42. 19F NMR spectroscopy of hexafluorobenzene. Int. J. Radiat. Oncol. Biol. Phys. 40, 161-171 (1998).
43. D. Zhao, A. Constantinescu, L. Jiang, E. W. Hahn and R. P. Mason, Prognostic radiology: Quantitative assessment of tumor oxygen dynamics by MRI. Am. J. Clin. Oncol. 24, 462-466 (2001).
44. R. P. Mason, S. Ran and P. E. Thorpe, Quantitative assessment of tumor oxygen dynamics: Molecular imaging for prognostic radiology. J. Cell. Biochem. 87, 45-53 (2002).
45. R. P. Mason, S. Hunjan, D. Le, C. Constantinescu, B. R. Barker, P. S. Wong, P. Peschke, E. W. Hahn and P. P. Antich, Regional tumor oxygen tension: Fluorine echo planar imaging of hexafluorobenzene reveals heterogeneity of dynamics. Int. J. Radiat. Oncol. Biol. Phys. 42, 747-750 (1998).
46. R. P. Mason, P. P. Antich, E. E. Babcock, A. Constantinescu, P. Peschke and E. W. Hahn, Noninvasive determination of tumor oxygen tension and local variation with growth. Int. J. Radiat. Oncol. Biol. Phys. 29, 95-103 (1994).
47. 19F MRI of perfluorocarbons. Curr. Sci. 76, 753-762 (1999).
48. 19F echo planar NMR imaging of sequestered perfluorocarbon. J. Magn. Reson. Imaging 4, 595-602 (1994).
49. H. Liu, Y. Song, K. L. Worden, X. Jiang, A. Constantinescu and R. P. Mason, Noninvasive investigation of blood oxygenation dynamics of tumors by near-infrared spectroscopy. Appl. Optic 39, 5231-5243 (2000).
50. D. W. Siemann, I. M. Johansen and M. R. Horsman, Radiobiological hypoxia in the KHT sarcoma: Predictions using the Eppendorf histograph. Int. J. Radiat. Oncol. Biol. Phys. 40, 1171-1176 (1998).
51. A. Fyles, M. Milosevic, M. Hedley, M. Pintile, W. Levin, L. Manchul and R. P. Hill, Tumor hypoxia has independent predictor impact only on patients with node-negative cervix cancer. J. Clin. Oncol. 20, 680-687 (2002).
52. S. Walenta, M. Wetterling, M. Leherke, G. Schwichert, K. Sundfør, E. K. Rofstad and W. Mueller-Klieser, High lactate levels predicts likelihood of metastasis, tumor regrowth, and patient survival in human cervix cancers. Cancer Res. 60, 916-927 (2000).
53. M. Höckel, K. Schlenger, S. Höckel and P. Vaupel, Hypoxic cervical cancers with low apoptotic index are highly aggressive. Cancer Res. 59, 4525-4528 (1999).
54. H. Zhong, F. Agani, A. A. Baccala, E. Laughner, N. Rioseco-Camacho, W. B. Isaacs, J. W. Simons and G. L. Semenza, Increased expression of hypoxia inducible factor-1 alpha in rat and human prostate cancer. Cancer Res. 58, 5280-5284 (1998).
55. J. A. Loncaster, A. L. Harris, S. E. Davidson, J. P. Logue, R. D. Hunter, C. C. Wycoff, J. Pastorek, R. J. Ratcliffe, I. J. Stratford and C. M. L. West, Carbonic anhydrase (CA IX) expression, a potential new intrinsic marker of hypoxia: Correlation with tumor oxygen measurement and prognosis in locally advanced carcinoma of the cervix. Cancer Res. 61, 6394-6399 (2001).