Magnetic resonance imaging techniques for monitoring changes in tumor oxygenation and blood flow

Seminars in Radiation Oncology

Volumn 8, Issue 3, 1998, Pages 197-207

  Robinson, S P ^a   Howe, F A ^a   Rodrigues, L M ^a   Stubbs, M ^a   Griffiths, J R ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOGEN; DEOXYHEMOGLOBIN; FLUOROURACIL; IFOSFAMIDE; OXYGEN;

CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CAPILLARY DENSITY; DRUG EFFICACY; DRUG UPTAKE; FIBROSARCOMA; HUMAN; HYPERCAPNIA; HYPEROXIA; HYPOXIA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGEN TENSION; PRIORITY JOURNAL; PROLACTINOMA; REVIEW; TISSUE OXYGENATION; TUMOR BLOOD FLOW; VASODILATATION;

EID: 0031926559     PISSN: 10534296     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1053-4296(98)80045-3     Document Type: Article

References (63)

1. Gray LH Conger AD Ebert M The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy Br J Radiol 26 1953 638 648
2. Teicher BA Lazo JS Sartorelli AC Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells Cancer Res 41 1981 73 81
3. Jain RK Determinants of tumor blood flow: A review Cancer Res 48 1988 2641 2658
4. Rojas A Carl U Reghebi K Effect of normobaric oxygen on tumor radiosensitivity: Fractionated studies Int J Radiat Oncol Biol Phys 18 1990 547 553
5. Chaplin DJ Horsman MR Aoki DS Nicotinamide, Fluosol DA and carbogen: A strategy to reoxygenate acutely and chronically hypoxic cells in vivo Br J Cancer 63 1991 109 113
6. Kjellen E Joiner MC Collier JM A therapeutic benefit from combining normobaric carbogen or oxygen with nicotinamide in fractionated X-ray treatments Radiother Oncol 22 1991 81 91
7. (suppl) Rojas A Radiosensitisation with normobaric oxygen and carbogen Radiother Oncol 20 1991 65 70
8. Grau C Horsman MR Overgaard J Improving the radiation response in a C3H mouse mammary carcinoma by normobaric oxygen or carbogen breathing Int J Radiat Oncol Biol Phys 22 1992 415 419
9. Chaplin DJ Horsman MR Siemann DW Further evaluation of nicotinamide and carbogen as a strategy to reoxygenate hypoxic cells in vivo: Importance of nicotinamide dose and pre-irradiation breathing time Br J Cancer 68 1993 269 273
10. Stratford IJ Adams GE Bremner JCM Manipulation and exploitation of the tumor environment for therapeutic benefit Int J Radiat Biol 65 1994 85 94
11. (suppl) McCoy CL McIntyre DJO Robinson SP Magnetic resonance spectroscopy and imaging methods for measuring tumor and tissue oxygenation Br J Cancer 74 1996 S226 S231
12. 2 histography Int J Radiat Oncol Biol Phys 19 1990 953 961
13. Ogawa S Lee T-M Nayak AS Oxygenation-sensitive contrast in magnetic resonance image of rodent brain at high magnetic fields Magn Reson Med 14 1990 68 78
14. Kwong KK Belliveau JW Chesler DA Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation Proc Natl Acad Sci USA 89 1992 5675 5679
15. Turner R Jezzard P Wen H Functional mapping of the human visual cortex at 4 and 1.5 Tesla using deoxygenation contrast EPI Magn Reson Med 29 1993 277 279
16. Duyn JH Moonen CTW van Yperen GE Inflow versus deoxyhaemoglobin effects in “BOLD” functional MRI using gradient echoes at 1.5T NMR in Biomed 7 1994 83 88
17. * and resonance frequency weighted magnetic resonance images of rodent tumors NMR Biomed 7 1994 3 11
18. *-weighted images during hyperoxia differentiate tumors from normal tissue Magn Reson Med 33 1995 318 325
19. Robinson SP Howe FA Griffiths JR Noninvasive monitoring of carbogen-induced changes in tumor blood flow and oxygenation by functional magnetic resonance imaging Int J Radiat Oncol Biol Phys 33 1995 855 859
20. Robinson SP Rodrigues LM Ojugo ASE The response to carbogen breathing in experimental tumor models monitored by gradient-recalled magnetic resonance imaging Br J Cancer 75 1997 1000 1006
21. * during carbogen breathing quantified with ME-FLASH Proceedings of the 5th Annual Meeting of the International Society for Magnetic Resonance in Medicine Vancouver 1997 1091
22. Peller L Weissfloch MK Stehling R Oxygen induced MR-signal changes in murine tumors Proceedings of the 5th Annual Meeting of the International Society for Magnetic Resonance in Medicine Vancouver 1997 1565
23. Lemieux SK Dorie MJ Glover GH Tumor response to changes of breathing gas mapped by the functional magnetic resonance imaging technique Proceedings of the 3rd Annual Meeting of the Society of Magnetic Rosonance Nice 1995 898
24. Ogawa S Menon RS Tank DW Functional brain mapping by blood oxygenation level-dependent contrast magnetic resonance imaging: A comparison of signal characteristics with a biophysical model Biophys J 64 1993 803 812
25. Kennan RP Scanley BE Gore JC Physiologic basis for BOLD MR signal changes due to hypoxia/hyperoxia: Separation of blood volume and magnetic susceptibility effects Magn Reson Med 37 1997 953 956
26. 31P MRS NMR Biomed 9 1996 208 216
27. Howe FA Robinson SP Griffiths JR Discrimination of blood flow and oxygenation changes in rat tumors in response to carbogen breathing Proceedings of the 3rd Annual Meeting of the Society of Magnetic Resonance Nice 1995 64
28. Tadamura E Hatabu H Li W Effect of oxygen inhalation on relaxation times in various tissues J Magn Reson Imag 7 1997 220 225
29. Robinson SP Kuchel MG Griffiths JR Deuterium MRI/MRS evidence for carbogen-induced increases in tumour blood flow Proceedings of the 4th Annual Meeting of the International Society for Magnetic Resonance in Medicine New York 1996 1103
30. Oikawa H Al-Hallaq HA Lewis MZ Spectroscopic imaging of the water resonance with short repetition time to study tumor response to hyperoxia Magn Reson Med 38 1997 27 32
31. Gray LH Steadman JM Determination of the oxyhaemoglobin dissociation curves for mouse and rat blood J Physiol 175 1964 161 171
32. Hall FG Minimal utilizable oxygen and the oxygen dissociation curve of blood of rodents J Appl Physiol 21 1966 375 378
33. Brizel DM Lin S Johnson JL The mechanisms by which hyperbaric oxygen and carbogen improve tumor oxygenation Br J Cancer 72 1995 1120 1124
34. (suppl) Dewhirst MW Ong ET Rosner GL Arteriolar oxygenation in tumor and subcutaneous arterioles: Effects of inspired air oxygen content Br J Cancer 74 1996 S241 S246
35. 2 histography Br J Cancer 66 1992 919 924
36. 2 and radiosensitivity of tumors by Fluosol-DA (20%) and carbogen Cancer Res 47 1987 442 446
37. Nordsmark M Grau C Horsman MR Relationship between tumour oxygenation, bioenergetic status and radiobiological hypoxia in an experimental model Acta Oncol 34 1995 329 334
38. 2, microcirculatory function and radiosensitivity Int J Radiat Oncol Biol Phys 40 1998 943 951
39. Al-Hallaq HA River JN Lewis MZ Correlation of MR and oxygen microelectrode measurements of the effects of hyperoxia on tumor oxygenation Proceedings of the 5th Annual Meeting of the International Society for Magnetic Resonance in Medicine Vancouver 1997 493
40. Young WK Vojnovic B Wardman P Measurement of oxygen tension in tumors by time-resolved fluorescence Br J Cancer 74 1996 S256 S259
41. Robinson SP Howe FA Griffiths JR Tumor response to hypercapnia and hyperoxia monitored by gradient-recalled echo magnetic resonance imaging Proccedings of the 4th Annual Meeting of the International Society for Magnetic Resonance in Medicine New York 1996 1104
42. Bhujwalla ZM Shungu DC Glickson JD Susceptibility maps of tumors and their relationship to histopathological characteristics and flow Proceedings of the 12th Annual Meeting of the Society of Magnetic Resonance in Medicine New York 1993 142
43. Vexler VS de Crespigny AJS Wendland MF MR imaging of blood oxygenation-dependent changes in focal renal ischemia and transplanted liver tumor in rat J Magn Reson Imaging 3 1993 483 490
44. * response after carbogen breathing Proceedings of the 5th Annual Meeting of the International Society for Magnetic Resonance in Medicine Vancouver 1997 2082
45. Karczmar GS Kuperman VY Lewis MZ Inhalation of 100% oxygen may decrease oxygenation in some tumor regions; magnetic resonance evidence for an intratumoral steal effect Proceedings of the 3rd Annual Meeting of the Society of Magnetic Resonance Nice 1995 1678
46. Song CW Levitt SH Quantitative study of vascularity in Walker carcinoma 256 Cancer Res 31 1971 587 589
47. Braunschweiger PG Schiffer LM Effect of dexamethasone on vascular function in RIF-1 tumors Cancer Res 46 1986 3299 3303
48. Griffiths JR Taylor NJ Howe FA The response of human tumors to carbogen breathing, monitored by gradient-recalled echo magnetic resonance imaging Int J Radiat Oncol Biol Phys 39 1997 697 701
49. 31P nuclear magnetic resonance spectroscopy Cancer Res 50 1990 7252 7256
50. 2 and radiation response in an experimental tumor model Br J Cancer 76 1997 1432 1439
51. Stubbs M Robinson SP Rodrigues LM Carbogen breathing causes an increased pH gradient across the cell membrane in rat hepatomas Proceedings of the 4th Annual Meeting of the International Society for Magnetic Resonance in Medicine New York 1996 1115
52. 2) breathing Proceedings of the 5th Annual Meeting of the International Society for Magnetic Resonance in Medicine Vancouver 1997 1093
53. Okunieff P McFarland E Rummeny E Effects of oxygen on the metabolism of murine tumors using in vivo phosphorus-31 NMR Am J Clin Oncol 10 1987 475 482
54. Terpstra M High WB Luo Y Relationships among lactate concentration, blood flow and histopathologic profiles in rat C6 glioma NMR Biomed 9 1996 185 194
55. 31P MRS in rat tumors: Increased uptake and cytotoxicity induced by carbogen breathing in GH3 prolactinomas Br J Cancer 75 1997 62 68
56. 31P NMR study in GH3 prolactinomas Proceedings of the 5th Annual Meeting of the International Society for Magnetic Resonance in Medicine Vancouver 1997 1094
57. McSheehy PMJ Robinson SP Ojugo ASE Carbogen breathing increases 5FU uptake and cytotoxicity in hypoxic RIF-1 tumours: A magnetic resonance study in vivo Cancer Res 58 1998 1185 1194
58. Carr P Graves JE Poston I Carbon dioxide induced vasorelaxation in rat mesenteric small arteries precontracted with noradrenaline is endothelium dependent and mediated by nitric oxide Pflugers Arch 423 1993 343 345
59. 31P MRS Proceedings of the 5th Annual Meeting of the International Society for Magnetic Resonance in Medicine Vancouver 1997 1092
60. Wood PJ Stratford IJ Adams GE Modification of energy metabolism and radiation response of a murine tumor by changes in nitric oxide availability Biochem Biophys Res Commun 192 1993 505 510
61. Andrade SP Hart IR Piper PJ Inhibitors of nitric oxide synthase selectively reduce flow in tumor-associated neovasculature Br J Pharmacol 107 1992 1092 1095
62. Meyer RE Shan S DeAngelo J Nitric oxide synthase inhibition irreversibly decreases perfusion in the R3230Ac rat mammary adenocarcinoma Br J Cancer 71 1995 1169 1174
63. Tozer GM Prise VE Chaplin DJ Inhibition of nitric oxide synthase induces a selective reduction in tumor blood flow that is reversible with L-arginine Cancer Res 57 1997 948 955