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Volumn 31, Issue 12, 2003, Pages 3050-3056

Single-chain Tet transregulators

Author keywords

[No Author keywords available]

Indexed keywords

DIMER; MONOMER; REGULATOR PROTEIN; REPRESSOR PROTEIN; HYBRID PROTEIN; TETRACYCLINE RESISTANCE ENCODING TRANSPOSON REPRESSOR PROTEIN; TETRACYCLINE RESISTANCE-ENCODING TRANSPOSON REPRESSOR PROTEIN; TRANSACTIVATOR PROTEIN;

EID: 0037901855     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkg421     Document Type: Article
Times cited : (41)

References (38)
  • 1
    • 0032485879 scopus 로고    scopus 로고
    • Single-chain lambda Cro repressors confirm high intrinsic dimer-DNA affinity
    • Jana,R., Hazbun,T.R., Fields,J.D. and Mossing,M.C. (1998) Single-chain lambda Cro repressors confirm high intrinsic dimer-DNA affinity. Biochemistry, 37, 6446-6455.
    • (1998) Biochemistry , vol.37 , pp. 6446-6455
    • Jana, R.1    Hazbun, T.R.2    Fields, J.D.3    Mossing, M.C.4
  • 2
    • 0031582086 scopus 로고    scopus 로고
    • Single-chain repressors containing engineered DNA-binding domains of the phage 434 repressor recognize symmetric or asymmetric DNA operators
    • Simoncsits,A., Chen,J., Percipalle,P., Wang,S., Toro,I. and Pongor,S. (1997) Single-chain repressors containing engineered DNA-binding domains of the phage 434 repressor recognize symmetric or asymmetric DNA operators. J. Mol. Biol., 267, 118-131.
    • (1997) J. Mol. Biol. , vol.267 , pp. 118-131
    • Simoncsits, A.1    Chen, J.2    Percipalle, P.3    Wang, S.4    Toro, I.5    Pongor, S.6
  • 3
    • 0029671279 scopus 로고    scopus 로고
    • Covalent attachment of Arc repressor subunits by a peptide linker enhances affinity for operator DNA
    • Robinson,C.R. and Sauer,R.T. (1996) Covalent attachment of Arc repressor subunits by a peptide linker enhances affinity for operator DNA. Biochemistry, 35, 109-116.
    • (1996) Biochemistry , vol.35 , pp. 109-116
    • Robinson, C.R.1    Sauer, R.T.2
  • 4
    • 0032520645 scopus 로고    scopus 로고
    • Single chain dimers of MASH-1 bind DNA with enhanced affinity
    • Sieber,M. and Allemann,R.K. (1998) Single chain dimers of MASH-1 bind DNA with enhanced affinity. Nucleic Acids Res., 26, 1408-1413.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 1408-1413
    • Sieber, M.1    Allemann, R.K.2
  • 7
    • 0034087676 scopus 로고    scopus 로고
    • Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system
    • Orth,P., Schnappinger,D., Hillen,W., Saenger,W. and Hinrichs,W. (2000) Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system. Nature Struct. Biol., 7, 215-219.
    • (2000) Nature Struct. Biol. , vol.7 , pp. 215-219
    • Orth, P.1    Schnappinger, D.2    Hillen, W.3    Saenger, W.4    Hinrichs, W.5
  • 8
    • 0034043511 scopus 로고    scopus 로고
    • Observing conformational and activity changes of Tet repressor in vivo
    • Tiebel,B., Garke,K. and Hillen,W. (2000) Observing conformational and activity changes of Tet repressor in vivo. Nature Struct. Biol., 7, 479-481.
    • (2000) Nature Struct. Biol. , vol.7 , pp. 479-481
    • Tiebel, B.1    Garke, K.2    Hillen, W.3
  • 9
    • 0012519031 scopus 로고    scopus 로고
    • Tetracyclines in the control of gene expression in eukaryotes
    • Nelson,M., Hillen,W. and Greenwald,R.A. (eds), Birkhäuser Verlag, Berlin
    • Bujard,H. and Gossen,M. (2001) Tetracyclines in the control of gene expression in eukaryotes. In Nelson,M., Hillen,W. and Greenwald,R.A. (eds), Tetracyclines in Biology, Chemistry and Medicine. Birkhäuser Verlag, Berlin, pp. 139-157.
    • (2001) Tetracyclines in Biology, Chemistry and Medicine , pp. 139-157
    • Bujard, H.1    Gossen, M.2
  • 10
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • Gossen,M. and Bujard,H. (1992) Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl Acad. Sci. USA, 89, 5547-5551.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 12
    • 0034608802 scopus 로고    scopus 로고
    • Exploring the sequence space for tetracycline-dependent transcriptional activators: Novel mutations yield expanded range and sensitivity
    • Urlinger,S., Baron,U., Thellmann,M., Hasan,M.T., Bujard,H. and Hillen,W. (2000) Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity. Proc. Natl Acad. Sci. USA, 97, 7963-7968.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 7963-7968
    • Urlinger, S.1    Baron, U.2    Thellmann, M.3    Hasan, M.T.4    Bujard, H.5    Hillen, W.6
  • 13
    • 0030797223 scopus 로고    scopus 로고
    • Tetracycline-controlled transcription in eukaryotes: Novel transactivators with graded transactivation potential
    • Baron,U., Gossen,M. and Bujard,H. (1997) Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential. Nucleic Acids Res., 25, 2723-2729.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2723-2729
    • Baron, U.1    Gossen, M.2    Bujard, H.3
  • 14
    • 0034682039 scopus 로고    scopus 로고
    • The p65 domain from NF-κB is an efficient human activator in the tetracycline-regulatable gene expression system
    • Urlinger,S., Helbl,V., Guthmann,J., Pook,E., Grimm,S. and Hillen,W. (2000) The p65 domain from NF-κB is an efficient human activator in the tetracycline-regulatable gene expression system. Gene, 247, 103-110.
    • (2000) Gene , vol.247 , pp. 103-110
    • Urlinger, S.1    Helbl, V.2    Guthmann, J.3    Pook, E.4    Grimm, S.5    Hillen, W.6
  • 15
    • 0035866302 scopus 로고    scopus 로고
    • A novel tetracycline-dependent transactivator with E2F4 transcriptional activation domain
    • Akagi,K., Kanai,M., Saya,H., Kozu,T. and Berns,A. (2001) A novel tetracycline-dependent transactivator with E2F4 transcriptional activation domain. Nucleic Acids Res., 29, e23.
    • (2001) Nucleic Acids Res. , vol.29
    • Akagi, K.1    Kanai, M.2    Saya, H.3    Kozu, T.4    Berns, A.5
  • 16
    • 0028897720 scopus 로고
    • Tetracycline-reversible silencing of eukaryotic promoters
    • Deuschle,U., Meyer,W.K. and Thiesen,H.J. (1995) Tetracycline-reversible silencing of eukaryotic promoters. Mol. Cell. Biol., 15, 1907-1914.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1907-1914
    • Deuschle, U.1    Meyer, W.K.2    Thiesen, H.J.3
  • 17
    • 0031740332 scopus 로고    scopus 로고
    • Tetracycline-regulatable factors with distinct dimerization domains allow reversible growth inhibition by p16
    • Rossi,F.M., Guicherit,O.M., Spicher,A., Kringstein,A.M., Fatyol,K., Blakely,B.T. and Blau,H.M. (1998) Tetracycline-regulatable factors with distinct dimerization domains allow reversible growth inhibition by p16. Nature Genet., 20, 389-393.
    • (1998) Nature Genet. , vol.20 , pp. 389-393
    • Rossi, F.M.1    Guicherit, O.M.2    Spicher, A.3    Kringstein, A.M.4    Fatyol, K.5    Blakely, B.T.6    Blau, H.M.7
  • 18
    • 0033555764 scopus 로고    scopus 로고
    • Tetracycline-inducible expression systems with reduced basal activity in mammalian cells
    • Forster,K., Helbl,V., Lederer,T., Urlinger,S., Wittenburg,N. and Hillen,W. (1999) Tetracycline-inducible expression systems with reduced basal activity in mammalian cells. Nucleic Acids Res., 27, 708-710.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 708-710
    • Forster, K.1    Helbl, V.2    Lederer, T.3    Urlinger, S.4    Wittenburg, N.5    Hillen, W.6
  • 19
    • 0032600013 scopus 로고    scopus 로고
    • A tetracycline controlled activation/repression system with increased potential for gene transfer into mammalian cells
    • Freundlieb,S., Schirra-Muller,C. and Bujard,H. (1999) A tetracycline controlled activation/repression system with increased potential for gene transfer into mammalian cells. J. Gene Med., 1, 4-12.
    • (1999) J. Gene Med. , vol.1 , pp. 4-12
    • Freundlieb, S.1    Schirra-Muller, C.2    Bujard, H.3
  • 20
    • 0033514374 scopus 로고    scopus 로고
    • Generation of conditional mutants in higher eukaryotes by switching between the expression of two genes
    • Baron,U., Schnappinger,D., Helbl,V., Gossen,M., Hillen,W. and Bujard,H. (1999) Generation of conditional mutants in higher eukaryotes by switching between the expression of two genes. Proc. Natl Acad. Sci. USA, 96, 1013-1018.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 1013-1018
    • Baron, U.1    Schnappinger, D.2    Helbl, V.3    Gossen, M.4    Hillen, W.5    Bujard, H.6
  • 21
    • 0028030082 scopus 로고
    • Mechanisms underlying expression of Tn10 encoded tetracycline resistance
    • Hillen,W. and Berens,C. (1994) Mechanisms underlying expression of Tn10 encoded tetracycline resistance. Annu. Rev. Microbiol., 48, 345-369.
    • (1994) Annu. Rev. Microbiol. , vol.48 , pp. 345-369
    • Hillen, W.1    Berens, C.2
  • 22
    • 0031003035 scopus 로고    scopus 로고
    • The role of the variable region in Tet repressor for inducibility by tetracycline
    • Berens,C., Schnappinger,D. and Hillen,W. (1997) The role of the variable region in Tet repressor for inducibility by tetracycline. J. Biol. Chem., 272, 6936-6942.
    • (1997) J. Biol. Chem. , vol.272 , pp. 6936-6942
    • Berens, C.1    Schnappinger, D.2    Hillen, W.3
  • 23
    • 0025995751 scopus 로고
    • Selection for Tn10 tet repressor binding to ter operator in Escherichia coli: Isolation of temperature-sensitive mutants and combinatorial mutagenesis in the DNA binding motif
    • Wissmann,A., Wray,L.V.,Jr, Somaggio,U., Baumeister,R., Geissendörfer,M. and Hillen,W. (1991) Selection for Tn10 tet repressor binding to ter operator in Escherichia coli: isolation of temperature-sensitive mutants and combinatorial mutagenesis in the DNA binding motif. Genetics, 128, 225-232.
    • (1991) Genetics , vol.128 , pp. 225-232
    • Wissmann, A.1    Wray Jr., L.V.2    Somaggio, U.3    Baumeister, R.4    Geissendörfer, M.5    Hillen, W.6
  • 24
    • 0003785155 scopus 로고
    • Cold Spring Harbour Laboratory Press, Cold Spring Harbour, NY
    • Miller,J.H. (1972) Experiments in Molecular Genetics. Cold Spring Harbour Laboratory Press, Cold Spring Harbour, NY.
    • (1972) Experiments in Molecular Genetics
    • Miller, J.H.1
  • 27
    • 0026556568 scopus 로고
    • The role of the N terminus in Tet repressor for ter operator binding determined by a mutational analysis
    • Berens,C., Altschmied,L. and Hillen,W. (1992) The role of the N terminus in Tet repressor for ter operator binding determined by a mutational analysis. J. Biol. Chem., 267, 1945-1952.
    • (1992) J. Biol. Chem. , vol.267 , pp. 1945-1952
    • Berens, C.1    Altschmied, L.2    Hillen, W.3
  • 28
    • 0028907431 scopus 로고
    • Consecutive low-usage leucine codons block translation only when near the 5′ end of a message in Escherichia coli
    • Goldman,E., Rosenberg,A.H., Zubay,G. and Studier,F.W. (1995) Consecutive low-usage leucine codons block translation only when near the 5′ end of a message in Escherichia coli. J. Mol. Biol., 245, 467-473.
    • (1995) J. Mol. Biol. , vol.245 , pp. 467-473
    • Goldman, E.1    Rosenberg, A.H.2    Zubay, G.3    Studier, F.W.4
  • 29
    • 0036216211 scopus 로고    scopus 로고
    • Tetracycline-dependent gene regulation: Combinations of transregulators yield a variety of expression windows
    • Knott,A., Garke,K., Urlinger,S., Guthmann,J., Müller,Y., Thellmann,M. and Hillen,W. (2002) Tetracycline-dependent gene regulation: combinations of transregulators yield a variety of expression windows. Biotechniques, 32, 796-807.
    • (2002) Biotechniques , vol.32 , pp. 796-807
    • Knott, A.1    Garke, K.2    Urlinger, S.3    Guthmann, J.4    Müller, Y.5    Thellmann, M.6    Hillen, W.7
  • 30
    • 0032568591 scopus 로고    scopus 로고
    • Optimizing the stability of single-chain proteins by linker length and composition mutagenesis
    • Robinson,C.R. and Sauer,R.T. (1998) Optimizing the stability of single-chain proteins by linker length and composition mutagenesis. Proc. Natl Acad. Sci. USA, 95, 5929-5934.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5929-5934
    • Robinson, C.R.1    Sauer, R.T.2
  • 33
    • 0035824107 scopus 로고    scopus 로고
    • Characteristics of adenovirus-mediated tetracycline-controllable expression system
    • 1568
    • Mizuguchi,H, and Hayakawa,T. (2001) Characteristics of adenovirus-mediated tetracycline-controllable expression system. Biochim. Biophys Acta, 1568, 21-29.
    • (2001) Biochim. Biophys. Acta , pp. 21-29
    • Mizuguchi, H.1    Hayakawa, T.2
  • 34
    • 0345301511 scopus 로고    scopus 로고
    • Use of the tetracycline controlled transcriptional silencer (tTS) to eliminate transgene leak in inducible overexpression transgenic mice
    • Zhu,Z., Ma,B., Homer,R.J., Zheng,T. and Elias,J.A. (2001) Use of the tetracycline controlled transcriptional silencer (tTS) to eliminate transgene leak in inducible overexpression transgenic mice. J. Biol. Chem., 30, 30.
    • (2001) J. Biol. Chem. , vol.30 , pp. 30
    • Zhu, Z.1    Ma, B.2    Homer, R.J.3    Zheng, T.4    Elias, J.A.5
  • 36
    • 0023805741 scopus 로고
    • Negative effect of the transcriptional activator GAL4
    • Gill,G. and Ptashne,M. (1988) Negative effect of the transcriptional activator GAL4. Nature, 334, 721-724.
    • (1988) Nature , vol.334 , pp. 721-724
    • Gill, G.1    Ptashne, M.2
  • 37
    • 0027472731 scopus 로고
    • Estradiol-inducible squelching and cell growth arrest by a chimeric VP16-estrogen receptor expressed in Saccharomyces cerevisiae: Suppression by an allele of PDR1
    • Gilbert,D.M., Heery,D.M., Losson,R., Chambon,P. and Lemoine,Y. (1993) Estradiol-inducible squelching and cell growth arrest by a chimeric VP16-estrogen receptor expressed in Saccharomyces cerevisiae: suppression by an allele of PDR1. Mol. Cell. Biol., 13, 462-472.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 462-472
    • Gilbert, D.M.1    Heery, D.M.2    Losson, R.3    Chambon, P.4    Lemoine, Y.5
  • 38
    • 0033992228 scopus 로고    scopus 로고
    • Herpes simplex virus transcriptional activator VP16 is detrimental to preimplantation development in mice
    • Yueh,Y.G., Yaworsky,P.J. and Kappen,C. (2000) Herpes simplex virus transcriptional activator VP16 is detrimental to preimplantation development in mice. Mol. Reprod. Dev., 55, 37-46.
    • (2000) Mol. Reprod. Dev. , vol.55 , pp. 37-46
    • Yueh, Y.G.1    Yaworsky, P.J.2    Kappen, C.3


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