Stress-induced gene expression in Candida albicans: Absence of a general stress response

Molecular Biology of the Cell

Volumn 14, Issue 4, 2003, Pages 1460-1467

  Enjalbert, Brice ^a   Nantel, André ^a   Whiteway, Malcolm ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; GLYCOGEN; TREHALOSE;

ARTICLE; CANDIDA ALBICANS; CELL PROTECTION; GENE EXPRESSION; GENE INDUCTION; GENETIC TRANSCRIPTION; HEAT SHOCK; NONHUMAN; OSMOTIC STRESS; OXIDATIVE STRESS; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; STRESS;

CANDIDA ALBICANS; CARBOHYDRATE METABOLISM; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENES, FUNGAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSMOTIC PRESSURE; OXIDATIVE STRESS; SACCHAROMYCES CEREVISIAE; SPECIES SPECIFICITY; TEMPERATURE;

CANDIDA; CANDIDA ALBICANS; EUKARYOTA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0037847543     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E02-08-0546     Document Type: Article

References (39)

1. Alarco, A.M., and Raymond, M. (1999). The bZip transcription factor Cap1p is involved in multidrug resistance and oxidative stress response in Candida albicans. J. Bacteriol. 181, 700-708.
2. Albertyn, J., Hohmann, S., Thevelein, J.M., and Prior, B.A. (1994). GPD1, which encodes glycerol-3-phosphate dehydrogenase, is essential for growth under osmotic stress in Saccharomyces cerevisiae, and its expression is regulated by the high-osmolarity glycerol response pathway. Mol. Cell. Biol. 14, 4135-4144.
3. Ansell, R., Granath, K., Hohmann, S., Thevelein, J.M., and Adler, L. (1997). The two isoenzymes for yeast NAD+-dependent glycerol 3-phosphate dehydrogenase encoded by GPD1 and GPD2 have distinct roles in osmoadaptation and redox regulation. EMBO J. 16, 2179-2187.
4. Arguelles, J.C. (1997). Thermotolerance and trehalose accumulation induced by heat shock in yeast cells of Candida albicans. FEMS Microbiol. Lett. 146, 65-71.
5. Boy-Marcotte, E., Lagniel, G., Perrot, M., Bussereau, F., Boudsocq, A., Jacquet, M., and Labarre, J. (1999). The heat shock response in yeast: differential regulations and contributions of the Msn2p/Msn4p and Hsf1p regulons. Mol. Microbiol. 33, 274-283.
6. Causton, H.C. et al. (2001). Remodeling of yeast genome expression in response to environmental changes. Mol. Biol. Cell 12, 323-337.
7. Estruch, F. (2000). Stress-controlled transcription factors, stress-induced genes and stress tolerance in budding yeast. FEMS Microbiol. Rev. 24, 469-486.
8. Garciadeblas, B., Rubio, F., Quintero, F.J., Banuelos, M.A., Haro, R., and Rodriguez-Navarro, A. (1993). Differential expression of two genes encoding isoforms of the ATPase involved in sodium efflux in Saccharomyces cerevisiae. Mol. Gen. Genet. 236, 363-368.
9. Gasch, A.P., Spellman, P.T., Kao, C.M., Carmel-Harel, O., Eisen, M.B., Storz, G., Botstein, D., and Brown, P.O. (2000). Genomic expression programs in the response of yeast cells to environmental changes. Mol. Biol. Cell 11, 4241-4257.
10. Gillum, A.M., Tsay, E.Y., and Kirsch, D.R. (1984). Isolation of the Candida albicans gene for orotidine-5′-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations. Mol. Gen. Genet. 198, 179-182.
11. Hohmann, S. (2002). Osmotic stress signaling and osmoadaptation in yeasts. Microbiol. Mol. Biol. Rev. 66, 300-372.
12. Jamieson, D.J., Stephen, D.W., and Terriere, E.C. (1996). Analysis of the adaptive oxidative stress response of Candida albicans. FEMS Microbiol. Lett. 138, 83-88.
13. Kadosh, D., and Johnson, A.D. (2001). Rfg1, a protein related to the Saccharomyces cerevisiae hypoxic regulator Rox1, controls filamentous growth and virulence in Candida albicans. Mol. Cell. Biol. 21, 2496-2505.
14. Lee, J., Godon, C., Lagniel, G., Spector, D., Garin, J., Labarre, J., and Toledano, M.B. (1999). Yap1 and Skn7 control two specialized oxidative stress response regulons in yeast. J. Biol. Chem. 274, 16040-16046.
15. Lewis, J.G., Learmonth, R.P., and Watson, K. (1995). Induction of heat, freezing and salt tolerance by heat and salt shock in Saccharomyces cerevisiae. Microbiology 141, 687-694.
16. Marchler, G., Schuller, C., Adam, G., and Ruis, H. (1993). A Saccharomyces cerevisiae UAS element controlled by protein kinase A activates transcription in response to a variety of stress conditions. EMBO J. 12, 1997-2003.
17. Martinez-Pastor, M.T., Marchler, G., Schuller, C., Marchler-Bauer, A., Ruis, H., and Estruch, F. (1996). The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE). EMBO J. 15, 2227-2235.
18. Murphy, J.W. (1991). Mechanisms of natural resistance to human pathogenic fungi. Annu. Rev. Microbiol. 45, 509-538.
19. Nantel, A. et al. (2002). Transcription profiling of C. albicans cells undergoing the yeast-to-hyphal transition. Mol. Biol. Cell. 10, 3452-3465.
20. Norbeck, J., Pahlman, A.K., Akhtar, N., Blomberg, A., and Adler, L. (1996). Purification and characterization of two isoenzymes of DL-glycerol-3-phosphatase from Saccharomyces cerevisiae. Identification of the corresponding GPP1 and GPP2 genes and evidence for osmotic regulation of Gpp2p expression by the osmosensing mitogen-activated protein kinase signal transduction pathway. J. Biol. Chem. 271, 13875-13881.
21. Parrou, J.L., Enjalbert, B., and Francois, J. (1999). STRE- and cAMP-independent transcriptional induction of Saccharomyces cerevisiae GSY2 encoding glycogen synthase during diauxic growth on glucose. Yeast 15, 1471-1484.
22. Parrou, J.L., and Francois, J. (1997). A simplified procedure for a rapid and reliable assay of both glycogen and trehalose in whole yeast cells. Anal. Biochem. 248, 186-188.
23. Parrou, J.L., Teste, M.A., and Francois, J. (1997). Effects of various types of stress on the metabolism of reserve carbohydrates in Saccharomyces cerevisiae: genetic evidence for a stress-induced recycling of glycogen and trehalose. Microbiology 143, 1891-1900.
24. Pesole, G., Lotti, M., Alberghina, L., and Saccone, C. (1995). Evolutionary origin of nonuniversal CUGSer codon in some Candida species as inferred from a molecular phylogeny. Genetics 141, 903-907.
25. Proft, M., and Serrano, R. (1999). Repressors and upstream repressing sequences of the stress-regulated ENA1 gene in Saccharomyces cerevisiae: bZIP protein Sko1p confers HOG-dependent osmotic regulation. Mol. Cell. Biol. 19, 537-546.
26. Rep, M., Reiser, V., Gartner, U., Thevelein, J.M., Hohmann, S., Ammerer, G., and Ruis, H. (1999). Osmotic stress-induced gene expression in Saccharomyces cerevisiae requires Msn1p and the novel nuclear factor Hot1p. Mol. Cell. Biol. 19, 5474-5485.
27. Ruis, H., and Schuller, C. (1995). Stress signaling in yeast. Bioessays 17, 959-965.
28. Santos, M.A., Cheesman, C., Costa, V., Moradas-Ferreira, P., and Tuite, M.F. (1999). Selective advantages created by codon ambiguity allowed for the evolution of an alternative genetic code in Candida spp. Mol. Microbiol. 31, 937-947.
29. Santos, M.A., Ueda, T., Watanabe, K., and Tuite, M.F. (1997). The non-standard genetic code of Candida spp.: an evolving genetic code or a novel mechanism for adaptation? Mol. Microbiol. 26, 423-431.
30. Schmitt, A.P., and McEntee, K. (1996). Msn2p, a zinc finger DNA-binding protein, is the transcriptional activator of the multistress response in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 93, 5777-5782.
31. Schuller, C., Brewster, J.L., Alexander, M.R., Gustin, M.C., and Ruis, H. (1994). The HOG pathway controls osmotic regulation of transcription via the stress response element (STRE) of the Saccharomyces cerevisiae CTT1 gene. EMBO J. 13, 4382-4389.
32. Seymour, I.J., and Piper, P.W. (1999). Stress induction of HSP30, the plasma membrane heat shock protein gene of Saccharomyces cerevisiae, appears not to use known stress-regulated transcription factors. Microbiology 145, 231-239.
33. Shi, Y., Mosser, D.D., and Morimoto, R.I. (1998). Molecular chaperones as HSF1-specific transcriptional repressors. Genes Dev. 12, 654-666.
34. Tusher, V.G., Tibshirani, R., and Chu, G. (2001). Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl. Acad. Sci. USA 98, 5116-5121.
35. Van Dijck, P., De Rop, L., Szlufcik, K., Van Ael, E., and Thevelein, J.M. (2002). Disruption of the Candida albicans TPS2 gene encoding trehalose-6-phosphate phosphatase decreases infectivity without affecting hypha formation. Infect. Immun. 70, 1772-1782.
36. Varela, J.C., Praekelt, U.M., Meacock, P.A., Planta, R.J., and Mager, W.H. (1995). The Saccharomyces cerevisiae HSP12 gene is activated by the high-osmolarity glycerol pathway and negatively regulated by protein kinase A. Mol. Biol. Cell 15, 6232-6245.
37. Wieser, R., Adam, G., Wagner, A., Schuller, C., Marchler, G., Ruis, H., Krawiec, Z., and Bilinski, T. (1991). Heat shock factor-independent heat control of transcription of the CTT1 gene encoding the cytosolic catalase T of Saccharomyces cerevisiae. J. Biol. Chem. 266, 12406-12411.
38. Zahringer, H., Thevelein, J.M., and Nwaka, S. (2000). Induction of neutral trehalase Nth1 by heat and osmotic stress is controlled by STRE elements and Msn2/Msn4 transcription factors: variations of PKA effect during stress and growth. Mol. Microbiol. 35, 397-406.
39. Zara, S., Antonio Farris, G., Budroni, M., and Bakalinsky, A.T. (2002). HSP12 is essential for biofilm formation by a Sardinian wine strain of S. cerevisiae. Yeast 19, 269-276.