Synergy of silent and hot spot mutations in importin β reveals a dynamic mechanism for recognition of a nuclear localization signal

Journal of Biological Chemistry

Volumn 278, Issue 18, 2003, Pages 16216-16221

  Koerner, Carolin ^a   Guan, Tinglu ^c   Gerace, Larry ^b   Cingolani, Gino ^c  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CHEMICAL BONDS; CONFORMATIONS; MOLECULAR STRUCTURE; MUTAGENESIS;

TRYPTOPHANS;

PROTEINS;

ALANINE; KARYOPHERIN BETA; TRYPTOPHAN;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; GENE MUTATION; MOLECULAR RECOGNITION; MUTAGENESIS; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STABILITY; SIGNAL DETECTION; ACTIVE TRANSPORT; ANIMAL; CELL LINE; CHEMISTRY; METABOLISM; PROTEIN SECONDARY STRUCTURE; RAT; SITE DIRECTED MUTAGENESIS;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; BETA KARYOPHERINS; BINDING SITES; CELL LINE; MUTAGENESIS, SITE-DIRECTED; NUCLEAR LOCALIZATION SIGNALS; PROTEIN STRUCTURE, SECONDARY; RATS; TRYPTOPHAN;

EID: 0037844882     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M301137200     Document Type: Article

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