Aryl-substituted and benzo-annulated cycloSal-derivatives of 2′,3′-dideoxy-2′,3′-didehydrothymidine monophosphate - Correlation of structure, hydrolysis properties and anti-HIV activity

Antiviral Chemistry and Chemotherapy

Volumn 13, Issue 2, 2002, Pages 129-141

  Ducho, Christian ^a   Balzarini, Jan ^b   Naesens, Lieve ^b   De Clercq, Erik ^b   Meier, Chris ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

31P NMR; CycloSal nucleotides; d4T; HIV; Pronucleotides; TK bypass

Indexed keywords

ANTIRETROVIRUS AGENT; BENZYL DERIVATIVE; ESTER DERIVATIVE; NAPHTHOL DERIVATIVE; SALIGENIN; STAVUDINE; STAVUDINE PHOSPHATE DERIVATIVE; THYMIDINE KINASE; THYMINE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROLYSIS; IN VITRO STUDY; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL;

EID: 0037832471     PISSN: 09563202     EISSN: None     Source Type: Journal    
DOI: 10.1177/095632020201300206     Document Type: Article

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