Design of new β1-selective adrenoceptor ligands as potential radioligands for in vivo imaging

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 16, 2003, Pages 3513-3527

  Kopka, Klaus ^a   Wagner, Stefan ^a   Riemann, Burkhard ^a   Law, Marilyn P ^a   Puke, Carsten ^a   Luthra, Sajinder K ^b   Pike, Victor W ^c   Wichter, Thomas ^a   Schmitz, Wilhelm ^a   Schober, Otmar ^a   Schäfers, Michael ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2 CYANOPHENOXY) 3 [2 (3 PHENYLUREIDO)ETHYLAMINO] 2 PROPANOL; ADRENERGIC RECEPTOR BLOCKING AGENT; RADIOLIGAND; BETA 1 ADRENERGIC RECEPTOR; CYANOIODOPINDOLOL; LIGAND; PROPANOLAMINE DERIVATIVE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG DESIGN; DRUG SYNTHESIS; HEART; IMAGING; ISOTOPE LABELING; MOUSE; NONHUMAN; PHOTON EMISSION TOMOGRAPHY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; ANIMAL; CHEMICAL STRUCTURE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DRUG ANTAGONISM; ENZYME SPECIFICITY; HEART MUSCLE; HEART VENTRICLE; HUMAN; IC 50; METABOLISM; METHODOLOGY; RADIOASSAY; TIME;

ANIMALS; HEART VENTRICLES; HUMANS; INHIBITORY CONCENTRATION 50; IODOCYANOPINDOLOL; LIGANDS; MICE; MOLECULAR STRUCTURE; MYOCARDIUM; PROPANOLAMINES; RADIOLIGAND ASSAY; RECEPTORS, ADRENERGIC, BETA-1; SUBSTRATE SPECIFICITY; TIME FACTORS; TOMOGRAPHY, EMISSION-COMPUTED; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 0037811441     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(03)00297-9     Document Type: Article

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