"Vinylogs" and "acetylenylogs" of β-adrenergic agents

Archiv der Pharmazie

Volumn 329, Issue 3, 1996, Pages 125-132

  Nudelman, Abraham ^a   Binnes, Yitschak ^a   Shmueli Broide, Naomi ^a   Odessa, Yael ^a   Hieble, J Paul ^b   Sulpizio, Anthony C ^b  

^a BAR ILAN UNIVERSITY   (Israel)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Adrenergic antagonists; Vinylogs; adrenergic agents; 1 adrenoceptors

Indexed keywords

BETA ADRENERGIC RECEPTOR; ETHANOLAMINE DERIVATIVE; PHENOXYPROPANOLAMINE DERIVATIVE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; HEART ATRIUM; HEART RATE; MALE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT; SMOOTH MUSCLE CONTRACTION;

ACETYLENE; ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; ATRIAL FUNCTION; MALE; MYOCARDIAL CONTRACTION; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP; VINYL COMPOUNDS;

EID: 0029870350     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/ardp.19963290304     Document Type: Article

References (28)

1. a) J.P. Hieble, Prog. Basic Clin. Pharmacol. 1991, 7, 105-177.
2. b) R.H. Uloth, J.R Kirk, W.A Gould, A.A. Larsen, J. Med. Chem. 1966, 9. 88-97.
3. c) C. Kaiser, T. Jen, E. Garvey, W. D. Bowen. J. Med. Chem. 1977, 20, 687-692.
4. Philips', N.V. Gloeiampenfabrieken, Neth. App., Jan 12, 1966, 6,407,943 Chem. Abstr. 1966, 64, 19488d.
5. a) T. Nishimura Bull. Chem. Soc. Jpn. 1952, 25, 54-56.
6. b) S. Israelashvili, Y. Gottlieb, M. Imber, A. Habas, J. Org. Chem. 1951, 16, 1519-1528.
7. c) G. Cignarella, E. Occelli, E. Testa, J. Med. Chem. 1965, 8, 326-331.
8. d) M.D. Taylor. R.J. Himmelsbach, B.E. Kornberg. J. Quin III, E. Lunney, A. Michel, J. Org. Chem. 1989, 54, 5585-5590.
9. e) B.R. Baker, M.H. Doll, J. Med. Chem. 1971,14, 793-799.
10. A. Merz, G. Markl, Angew. Chem. Int. Ed. Eng., 1973, 12, 845-846.
11. R. Paugam-Dreves, M. Baboulène, G Sturtz, Eur. J. Med. Chem. 1977, 12, 333-340.
12. N.M. Yoon, H.C. Brown, J. Am. Chem. Soc. 1968, 90, 2927-2938.
13. L.M. Braun, R.A. Braun, H.R. Crissman, O. Myles. R.M. Adams, J. Org. Chem. 1971, 36, 2388-2390.
14. A. Pelter, S. Singaram, H. Brown, Tetrahedron Lett. 1983, 24, 1433-1436.
15. R F. Meyer, C.D. Stratton, S.G. Hastings, R.M Corey, J. Med. Chem. 1973, 16, 1113-1116.
16. E Adlerova, V. Trcka, V. Smejkal, M Protiva, Coll. Czech Chem. Commun. 1969, 34, 479-484.
17. G Cignarella, E. Occelli, E. Testa, J. Med. Chem. 1965, 8, 326-331.
18. B.R. Baker, M.H. Doll, J. Med. Chem. 1971, 14, 793-799.
19. M.D Taylor, R.J. Himmelsbach, B.E. Kornberg, J. Quin, E. Lunney, A. Michel, J. Org. Chem. 1989, 54, 5585-5590
20. J.V Braun, J. Nelles, Chem. Ber. 1933, 66B, 1464-1470.
21. M. Tanaka, Tetrahedron Lett. 1980, 21, 2959-2962.
22. V.M. Micovic, M.L.J. Mihailovic, J. Org. Chem. 1953, 18, 1190-1200.
23. D.A. Ben Ephraim, Tetrahedron 1973, 29, 4111-4125.
24. J. Barluenga, F. Foubelo, F. Fananas, M. Yus, J. Chem. Soc. Perkin Trans, 1 1989, 553-557.
25. J. Bergmann, K. Takacs, Arch. Pharm. 1990, 323, 387-391.
26. D. Lehmann, R. Eckardt, G. Faust, W. Fiedler, Pharmazie 1980, 35, 278-284
27. W. Kunz, H. Jacobi, K. Koch. 1967 Ger. 1.236,523 Chem. Abstr. 1967, 67, 64046k.
28. H. Bercher, D. Ehlers, A. Gnsk, Pharmazie 1976, 31, 351-354.