Synthesis and in vitro and in vivo characteristics of an iodinated analogue of the β-adrenoceptor antagonist carazolol

Journal of Medicinal Chemistry

Volumn 39, Issue 17, 1996, Pages 3256-3262

  Dubois, Eric A ^a   Van Den Bos, Jan C ^b   Doornbos, Tamme ^b   Van Doremalen, Peter A P M ^b   Somsen, G Aernout ^a   Vekemans, Jozef A J M ^b   Janssen, Anton G M ^b   Batink, Harry D ^a   Boer, Gerard J ^a   Pfaffendorf, Martin ^a   Van Royen, Eric A ^a   Van Zwieten, Pieter A ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY) 2 BENZIMIDAZOLONE; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CARAZOLOL; CARAZOLOL DERIVATIVE; CYANOIODOPINDOLOL; IODINE 123; PROPRANOLOL; RADIOLIGAND; UNCLASSIFIED DRUG;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; DRUG DISTRIBUTION; DRUG RECEPTOR BINDING; DRUG SPECIFICITY; FRONTAL CORTEX; HEART ATRIUM MUSCLE; HEART VENTRICLE WALL; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; MALE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RABBIT; RADIOISOTOPE DISTRIBUTION; RECEPTOR AFFINITY; RECEPTOR DENSITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TISSUE DISTRIBUTION;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; BRAIN; CARBAZOLES; CELL MEMBRANE; HEART VENTRICLES; INDICATORS AND REAGENTS; IODINE RADIOISOTOPES; LUNG; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MYOCARDIUM; PROPANOLAMINES; RABBITS; RADIOLIGAND ASSAY; RECEPTORS, ADRENERGIC, BETA; TISSUE DISTRIBUTION;

EID: 10144254436     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960122v     Document Type: Article

References (28)

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