메뉴 건너뛰기




Volumn 59, Issue 1, 2003, Pages 161-170

P2Y receptors in brain astroglial cells: Identification of a gliotic P2Y receptor coupled to activation of a calcium-independent Ras/ERK1/2 pathway

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; CALCIUM; CYCLOOXYGENASE 2; ESTERASE INHIBITOR; GUANINE NUCLEOTIDE BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE METHYL ESTER; NOOTROPIC AGENT; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE PHOSPHODIESTERASE; PURINE P2Y RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; RAF PROTEIN; RAS PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRICYCLO[4.3.0.1]DECAN 9 YL XANTHOGENATE;

EID: 0037636457     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.10217     Document Type: Conference Paper
Times cited : (9)

References (45)
  • 1
    • 0028329654 scopus 로고
    • Modulation of astroglial cell proliferation by analogues of adenosine and ATP in primary cultures of rat striatum
    • Abbracchio MP, Saffrey MJ, Hopker V, Burnstock G. 1994. Modulation of astroglial cell proliferation by analogues of adenosine and ATP in primary cultures of rat striatum. Neuroscience 59:67-76.
    • (1994) Neuroscience , vol.59 , pp. 67-76
    • Abbracchio, M.P.1    Saffrey, M.J.2    Hopker, V.3    Burnstock, G.4
  • 2
    • 0029589668 scopus 로고
    • Effects of ATP analogues and basic fibroblast growth factor on astroglial cell differentiation in primary cultures of rat striatum
    • Abbracchio MP, Ceruti S, Langfelder R, Cattabeni F, Saffrey MJ, Burnstock G. 1995. Effects of ATP analogues and basic fibroblast growth factor on astroglial cell differentiation in primary cultures of rat striatum. Int J Dev Neurosci 13:685-693.
    • (1995) Int J Dev Neurosci , vol.13 , pp. 685-693
    • Abbracchio, M.P.1    Ceruti, S.2    Langfelder, R.3    Cattabeni, F.4    Saffrey, M.J.5    Burnstock, G.6
  • 5
    • 0031951999 scopus 로고    scopus 로고
    • Stimulation of phospholipase D via alpha1-adrenergic receptors in Madin-Darby canine kidney cells is independent of PKCalpha and -epsilon activation
    • Balboa MA, Insel PA. 1998. Stimulation of phospholipase D via alpha1-adrenergic receptors in Madin-Darby canine kidney cells is independent of PKCalpha and -epsilon activation. Mol Pharmacol 53:221-227.
    • (1998) Mol Pharmacol , vol.53 , pp. 221-227
    • Balboa, M.A.1    Insel, P.A.2
  • 8
    • 0034944344 scopus 로고    scopus 로고
    • Modulation of cyclooxygenase-2 and brain reactive astrogliosis by purinergic P2 receptors
    • Brambilla R, Abbracchio MP. 2001. Modulation of cyclooxygenase-2 and brain reactive astrogliosis by purinergic P2 receptors. Ann NY Acad Sci 939:54-62.
    • (2001) Ann NY Acad Sci , vol.939 , pp. 54-62
    • Brambilla, R.1    Abbracchio, M.P.2
  • 11
    • 18744383029 scopus 로고    scopus 로고
    • Induction of COX-2 and of reactive gliosis by P2Y receptors in rat cortical astrocytes is dependent on ERK1/2 but independent of calcium signaling
    • Brambilla R, Neary JT, Cattabeni F, Cottini L, D'Ippolito G, Schiller PC, Abbraccbio MP. 2002. Induction of COX-2 and of reactive gliosis by P2Y receptors in rat cortical astrocytes is dependent on ERK1/2 but independent of calcium signaling. J Neurochem 83:1285-1296.
    • (2002) J Neurochem , vol.83 , pp. 1285-1296
    • Brambilla, R.1    Neary, J.T.2    Cattabeni, F.3    Cottini, L.4    D'Ippolito, G.5    Schiller, P.C.6    Abbraccbio, M.P.7
  • 12
    • 0026659959 scopus 로고
    • Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein
    • Cox AD, Hisaka MM, Buss JE, Der CJ. 1992. Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein. Mol Cell Biol 12:2606-2615.
    • (1992) Mol Cell Biol , vol.12 , pp. 2606-2615
    • Cox, A.D.1    Hisaka, M.M.2    Buss, J.E.3    Der, C.J.4
  • 13
    • 0028922688 scopus 로고
    • Spatial memory deficits, increased phosphorylation of the transcription factor CREB, and induction of the AP-1 complex following experimental brain injury
    • Dash PK, Moore AN, Dixon CE. 1995. Spatial memory deficits, increased phosphorylation of the transcription factor CREB, and induction of the AP-1 complex following experimental brain injury. J Neurosci 15:2030-2039.
    • (1995) J Neurosci , vol.15 , pp. 2030-2039
    • Dash, P.K.1    Moore, A.N.2    Dixon, C.E.3
  • 14
    • 0030872062 scopus 로고    scopus 로고
    • Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase
    • Della Rocca GJ, van Biesen T, Daaka Y, Luttrell DK, Luttrell LM, Lefkowitz RJ. 1997. Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase. J Biol Chem 272:19125-19132.
    • (1997) J Biol Chem , vol.272 , pp. 19125-19132
    • Della Rocca, G.J.1    Van Biesen, T.2    Daaka, Y.3    Luttrell, D.K.4    Luttrell, L.M.5    Lefkowitz, R.J.6
  • 15
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam JD, Lebovitz RM, Roeder RG. 1993. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acid Res 11:1475-1489.
    • (1993) Nucleic Acid Res , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 16
    • 0002970907 scopus 로고    scopus 로고
    • Up-regulation of COX-2 and prostaglandin EP3 receptor mRNA expression in spinal cord in a clinical model of chronic inflammation
    • Dolan S, O'Shaughnessy PJ, Nolan AM. 1998. Up-regulation of COX-2 and prostaglandin EP3 receptor mRNA expression in spinal cord in a clinical model of chronic inflammation. Eur J Neurosci 10 (suppl 10):77.
    • (1998) Eur J Neurosci , vol.10 , Issue.SUPPL. 10 , pp. 77
    • Dolan, S.1    O'Shaughnessy, P.J.2    Nolan, A.M.3
  • 17
    • 0029670941 scopus 로고    scopus 로고
    • (2+)-dependent routes to Ras: Mechanisms for neuronal survival, differentiation, and plasticity?
    • (2+)-dependent routes to Ras: mechanisms for neuronal survival, differentiation, and plasticity? Neuron 16:233-236.
    • (1996) Neuron , vol.16 , pp. 233-236
    • Finkbeiner, S.1    Greenberg, M.E.2
  • 18
    • 0031600501 scopus 로고    scopus 로고
    • Growth factors and mitogen-activated protein kinases
    • Force T, Bonventre JV. 1998. Growth factors and mitogen-activated protein kinases. Hypertension 31:152-161.
    • (1998) Hypertension , vol.31 , pp. 152-161
    • Force, T.1    Bonventre, J.V.2
  • 19
    • 0035197226 scopus 로고    scopus 로고
    • P2 receptor-types involved in astrogliosis in vivo
    • Franke H, Krugel U, Illes P. 2001 P2 receptor-types involved in astrogliosis in vivo. Br J Pharmacol 134:1180-1189.
    • (2001) Br J Pharmacol , vol.134 , pp. 1180-1189
    • Franke, H.1    Krugel, U.2    Illes, P.3
  • 21
    • 0032489435 scopus 로고    scopus 로고
    • Modulation of cell signalling by ceramides
    • Gomez-Muñoz A. 1998. Modulation of cell signalling by ceramides. Biochim Biophys Acta 1391:92-109.
    • (1998) Biochim Biophys Acta , vol.1391 , pp. 92-109
    • Gomez-Muñoz, A.1
  • 22
    • 0032861127 scopus 로고    scopus 로고
    • Extracellular-signal-regulated kinase signalling in neurons
    • Grewal SS, York RD, Stork PJS. 1999. Extracellular-signal-regulated kinase signalling in neurons. Curr Opin Neurobiol 9:544-553.
    • (1999) Curr Opin Neurobiol , vol.9 , pp. 544-553
    • Grewal, S.S.1    York, R.D.2    Stork, P.J.S.3
  • 24
    • 0021751197 scopus 로고
    • Isoquinoline- sulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C
    • Hidaka H, Inagaki M, Kawamoto S, Sasaki L. 1984. Isoquinoline- sulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C. Biochemistry 23:5036-5041.
    • (1984) Biochemistry , vol.23 , pp. 5036-5041
    • Hidaka, H.1    Inagaki, M.2    Kawamoto, S.3    Sasaki, L.4
  • 25
    • 0033178889 scopus 로고    scopus 로고
    • Regional distribution of cyclooxygenase-2 in the hippocampal formation in Alzheimer's disease
    • Ho L, Pieroni C, Winger D, Purohit DP, Aisen PS, Pasinetti GM. 1999. Regional distribution of cyclooxygenase-2 in the hippocampal formation in Alzheimer's disease. J Neurosci Res 57:295-303.
    • (1999) J Neurosci Res , vol.57 , pp. 295-303
    • Ho, L.1    Pieroni, C.2    Winger, D.3    Purohit, D.P.4    Aisen, P.S.5    Pasinetti, G.M.6
  • 26
    • 0037163089 scopus 로고    scopus 로고
    • Activation of monocyte cyclooxygenase-2 gene expression by human herpesvirus 6. Role for cyclic AMP-responsive element-binding protein and activator protein-1
    • Janelle ME, Gravel A, Gosselin J, Tremblay MJ, Flamand L. 2002. Activation of monocyte cyclooxygenase-2 gene expression by human herpesvirus 6. Role for cyclic AMP-responsive element-binding protein and activator protein-1. J Biol Chem 277:30665-30674.
    • (2002) J Biol Chem , vol.277 , pp. 30665-30674
    • Janelle, M.E.1    Gravel, A.2    Gosselin, J.3    Tremblay, M.J.4    Flamand, L.5
  • 27
    • 0032077167 scopus 로고    scopus 로고
    • Phosphatidylcholine-specific phospholipase inhibitor D609 differentially affects MAP kinases and immediate-early genes in PC12 cells
    • Kahle PJ, Shooter EM, Johnson RM, Verity AN. 1998. Phosphatidylcholine-specific phospholipase inhibitor D609 differentially affects MAP kinases and immediate-early genes in PC12 cells. Cell Signal 10:321-330.
    • (1998) Cell Signal , vol.10 , pp. 321-330
    • Kahle, P.J.1    Shooter, E.M.2    Johnson, R.M.3    Verity, A.N.4
  • 28
    • 0029032249 scopus 로고
    • The regulation of AP-1 activity by mitogen-activated protein kinases
    • Karin M. 1995. The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 270:16483-16486.
    • (1995) J Biol Chem , vol.270 , pp. 16483-16486
    • Karin, M.1
  • 29
    • 0030694387 scopus 로고    scopus 로고
    • BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C
    • Kato Y, Kravchenko VV, Tapping RI, Han J, Ulevitch RJ, Lee JD. 1997. BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C. EMBO J 16:7054-7066.
    • (1997) EMBO J , vol.16 , pp. 7054-7066
    • Kato, Y.1    Kravchenko, V.V.2    Tapping, R.I.3    Han, J.4    Ulevitch, R.J.5    Lee, J.D.6
  • 31
    • 0029744885 scopus 로고    scopus 로고
    • Sounding the alarm: Protein kinase cascades activated by stress and inflammation
    • Kyriakis JM, Avruch J. 1996. Sounding the alarm: protein kinase cascades activated by stress and inflammation. J Biol Chem 271:24313-24316.
    • (1996) J Biol Chem , vol.271 , pp. 24313-24316
    • Kyriakis, J.M.1    Avruch, J.2
  • 32
    • 0028973293 scopus 로고
    • Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes
    • Lerner EC, Qian Y, Blaskovich MA, Fossum RD, Vogt A, Sun J, Cox AD, Der CJ, Hamilton AD, Sebti SM. 1995. Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes. J Biol Chem 270:26802-26806.
    • (1995) J Biol Chem , vol.270 , pp. 26802-26806
    • Lerner, E.C.1    Qian, Y.2    Blaskovich, M.A.3    Fossum, R.D.4    Vogt, A.5    Sun, J.6    Cox, A.D.7    Der, C.J.8    Hamilton, A.D.9    Sebti, S.M.10
  • 33
    • 1842333233 scopus 로고    scopus 로고
    • Regulation of astrocyte nitric oxide synthase type II expression by ATP and glutamate involves loss of transcription factor binding to DNA
    • Lin HL, Murphy S. 1997. Regulation of astrocyte nitric oxide synthase type II expression by ATP and glutamate involves loss of transcription factor binding to DNA. J Neurochem 69:612-616.
    • (1997) J Neurochem , vol.69 , pp. 612-616
    • Lin, H.L.1    Murphy, S.2
  • 34
    • 0034660691 scopus 로고    scopus 로고
    • Modulation of interleukin-1beta and tumor necrosis factor alpha signaling by P2 purinergic receptors in human fetal astrocytes
    • Liu JS, John GR, Sikora A, Lee SC, Brosnan CF. 2000. Modulation of interleukin-1beta and tumor necrosis factor alpha signaling by P2 purinergic receptors in human fetal astrocytes. J Neurosci 20:5292-5299.
    • (2000) J Neurosci , vol.20 , pp. 5292-5299
    • Liu, J.S.1    John, G.R.2    Sikora, A.3    Lee, S.C.4    Brosnan, C.F.5
  • 35
    • 0031906550 scopus 로고    scopus 로고
    • Signal transduction through NF-kappa B
    • May MJ, Ghosh S. 1998. Signal transduction through NF-kappa B. Immunol Today 19:80-88.
    • (1998) Immunol Today , vol.19 , pp. 80-88
    • May, M.J.1    Ghosh, S.2
  • 36
    • 0033624495 scopus 로고    scopus 로고
    • Activation of NFkappaB is necessary for IL-1beta-induced cyclooxygenase-2 (COX-2) expression in human gingival fibroblasts
    • Nakao S, Ogata Y, Shimizu-Sasaki E, Yamazaki M, Furuyama S, Sugiya H. 2000. Activation of NFkappaB is necessary for IL-1beta-induced cyclooxygenase-2 (COX-2) expression in human gingival fibroblasts. Mol Cell Biochem 209:113-118.
    • (2000) Mol Cell Biochem , vol.209 , pp. 113-118
    • Nakao, S.1    Ogata, Y.2    Shimizu-Sasaki, E.3    Yamazaki, M.4    Furuyama, S.5    Sugiya, H.6
  • 37
    • 0036715333 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha (TNF-α)-induced prostaglandin E2 release is mediated by the activation of cyclooxygenase-2 (COX-2) transcription via NFkappaB in human gingival fibroblasts
    • Nakao S, Ogata Y, Shimizu E, Yamazaki M, Furuyama S, Sugiya H. 2002. Tumor necrosis factor alpha (TNF-α)-induced prostaglandin E2 release is mediated by the activation of cyclooxygenase-2 (COX-2) transcription via NFkappaB in human gingival fibroblasts. Mol Cell Biochem 238:11-18.
    • (2002) Mol Cell Biochem , vol.238 , pp. 11-18
    • Nakao, S.1    Ogata, Y.2    Shimizu, E.3    Yamazaki, M.4    Furuyama, S.5    Sugiya, H.6
  • 39
    • 0033153149 scopus 로고    scopus 로고
    • Mitogenic signaling by ATP/P2Y purinergic receptors in astrocytes: Involvement of a calcium-independent protein kinase C, extracellular signal-regulated protein kinase pathway distinct from the phosphatidylinositol-specific phospholipase C/calcium pathway
    • Neary JT, Kang Y, Bu Y, Yu E, Akong K, Peters CM. 1999. Mitogenic signaling by ATP/P2Y purinergic receptors in astrocytes: involvement of a calcium-independent protein kinase C, extracellular signal-regulated protein kinase pathway distinct from the phosphatidylinositol-specific phospholipase C/calcium pathway. J Neurosci 19:4211-4220.
    • (1999) J Neurosci , vol.19 , pp. 4211-4220
    • Neary, J.T.1    Kang, Y.2    Bu, Y.3    Yu, E.4    Akong, K.5    Peters, C.M.6
  • 41
    • 0033965158 scopus 로고    scopus 로고
    • The p38 signal transduction pathway: Activation and function
    • Ono K, Han J. 2000. The p38 signal transduction pathway: activation and function. Cell Signal 12:1-13.
    • (2000) Cell Signal , vol.12 , pp. 1-13
    • Ono, K.1    Han, J.2
  • 43
    • 0035853840 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands suppress the transcriptional activation of cyclooxygenase-2. Evidence for involvement of activator protein-1 and CREB-binding protein/ p300
    • Subbaramaiah K, Lin DT, Hart JC, Dannenberg AJ. 2001. Peroxisome proliferator-activated receptor gamma ligands suppress the transcriptional activation of cyclooxygenase-2. Evidence for involvement of activator protein-1 and CREB-binding protein/ p300. J Biol Chem 276:12440-12448.
    • (2001) J Biol Chem , vol.276 , pp. 12440-12448
    • Subbaramaiah, K.1    Lin, D.T.2    Hart, J.C.3    Dannenberg, A.J.4
  • 44
    • 0037166271 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: Evidence for involvement of AP-1 and PEA3
    • Subbaramaiah K, Norton L, Gerald W, Dannenberg AJ. 2002. Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: evidence for involvement of AP-1 and PEA3. J Biol Chem 277:18649-18657.
    • (2002) J Biol Chem , vol.277 , pp. 18649-18657
    • Subbaramaiah, K.1    Norton, L.2    Gerald, W.3    Dannenberg, A.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.