Regulation of astrocyte nitric oxide synthase type II expression by ATP and glutamate involves loss of transcription factor binding to DNA

Journal of Neurochemistry

Volumn 69, Issue 2, 1997, Pages 612-616

  Lin, Hsin Lee ^a   Murphy, Sean ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Astrocyte; ATP; Gene regulation; Glutamate; Nitric oxide synthase; Nuclear factor B

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUTAMIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN INJURY; DNA BINDING; ENZYME REGULATION; GENE EXPRESSION REGULATION; NERVE CELL CULTURE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; STROKE; TRANSCRIPTION REGULATION;

ANIMALIA;

EID: 1842333233     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.69020612.x     Document Type: Article

References (29)

1. Arenander A. T. and de Vellis J. (1993) Early response gene expression signifying functional coupling of neuroligand receptor systems in astrocytes, in Astrocytes (Murphy S., ed). pp. 109-136. Academic Press, San Diego.
2. Bruner G., Simmons M. L., and Murphy S. (1993) Astrocytes: targets and sources for purines, eicosanoids, and nitrosyl compounds, in Astrocytes (Murphy S., ed), pp. 89-108. Academic Press, San Diego.
3. Chandler L. J., Kopnisky K., Richards E., Crews F. T., and Sumners C. (1995) Angiotensin II decreases inducible nitric oxide synthase expression in rat astroglial cultures. Am. J. Physiol. 268, C700-C707.
4. Endoh M., Maiese K., and Wagner J. A. (1994) Expression of the inducible form of nitric oxide synthase by reactive astrocytes after transient global ischemia. Brain Res. 651, 92-100.
5. Feinstein D. L., Galea E., and Reis D. J. (1993) Norepinephrine suppresses inducible nitric oxide synthase activity in rat astroglial cultures. J. Neurochem. 60, 1945-1948.
6. Feinstein D. L., Galea E., Roberts S., Berquist H., Wang H., and Reis D. J. (1994) Induction of nitric oxide synthase in rat C6 glioma cells. J. Neurochem. 62, 315-321.
7. Finkbeiner S. M. (1995) Modulation and control of intracellular calcium, in Neuroglia (Kettenmann H. and Ransom B. R., eds), pp. 273-288. Oxford University Press, New York.
8. Grzybicki D., Loihl A., Kardos S., Shelper R., Moore S. A., Glabinski A. R., Ransohoff R. M., and Murphy S. (1996) Expression of chemokines and nitric oxide synthase-2 following cerebral trauma. Soc. Neurosci. Abstr. 22, 1181.
9. Hardingham G. E., Chawla S., Johnson C. M., and Bading H. (1997) Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression. Nature 385, 260-265.
10. Hermann K., Raizada M. K., Sumners C., and Phillips M. I. (1988) Immunocytochemical and biochemical characterization of angiotensin I and II in cultured neuronal and glial cells from rat brains. Neuroendocrinology 47, 125-132.
11. Jordan M. L., Rominski B., Jaquins-Gerstl A., Geller D., and Hoffman R. A. (1995) Regulation of inducible nitric oxide production by intracellular calcium. Surgery 118, 138-146.
12. Kimelberg H. K., Cai Z., Rastogi P., Charniga C. J., Goderie S., Dave V., and Jalonen T. O. (1997) Transmitter-induced calcium responses differ in astrocytes acutely isolated from rat brain and in culture. J. Neurochem. 68, 1088-1098.
13. Kirischuk S., Möller T., Voitenko N., Kettenmann H., and Verkhratsky A. (1995) ATP-induced cytoplasmic calcium mobilization in Bergmann glial cells. J. Neurosci. 15, 7861-7871.
14. Koka P., He K., Zack J. A., Kitchen S., Peacock W., Fried I., Tran T., Yashar S., and Merrill J. E. (1995) HIV-1 envelope proteins induce IL1, TNFα and nitric oxide in glial cultures derived from fetal, neonatal and adult human brain. J. Exp. Med. 182, 941-952.
15. Kopnisky K. L., Sumners C., and Chadler L. J. (1997) Cytokine- and endotoxin-induced nitric oxide synthase in rat astroglial cultures: differential modulation by angiotensin II. J. Neurochem. 68, 935-944.
16. Lyandvert L., Galea E., Xie Q.-W., Reis D. J., and Feinstein D. L. (1996) Norepinephrine suppressess astroglial NOS-2 expression at the level of promoter activation. Soc. Neurosci. Abstr. 22, 1733.
17. Murphy S. and Grzybicki D. (1996) Glial NO: normal and pathological roles. Neuroscientist 2, 91-100.
18. Murphy S., Simmons M. L., Agullo L., Garcia A., Feinstein D. L., Galea E., Reis D. J., Minc-Golomb D., and Schwartz J. P. (1993) Synthesis of nitric oxide in glial cells. Trends Neurosci. 16, 323-328.
19. Murphy S., Lin H. L., and Park S. K. (1995) Cytokine-induced expression of type II nitric oxide synthase expression in astrocytes is downregulated by ATP and glutamate. Glia 15, 77-82.
20. Ollivier V., Parry G. C. N., Cobb R. R., deProst D., and Mackman N. (1996) Elevated cAMP inhibits NF-κB-mediated transcription in human monocytic cells and endothelial cells. J. Biol. Chem. 271, 20828-20835.
21. Otero G. C. and Merrill J. E. (1994) Cytokine receptors on glial cells. Glia 11, 117-128.
22. Park S. K. and Murphy S. (1996) Nitric oxide synthase type II mRNA stability is translation- and transcription-dependent. J. Neurochem. 67, 1766-1769.
23. Park S. K., Lin H. L., and Murphy S. (1994) Nitric oxide limits transcriptional induction of nitric oxide synthase in CNS glial cells. Biochem. Biophys. Res. Commun. 201, 762-768.
24. Park S. K., Lin H. L., and Murphy S. (1997) Nitric oxide regulates nitric oxide synthase-2 gene expression by inhibiting NF-κB binding to DNA. Biochem. J. 322, 609-613.
25. Perella M. A., Patterson C., Tan L., Yet S.-F., Hsieh C.-M., Yoshozumi M., and Lee M.-E. (1996) Suppression of IL-1β-induced nitric oxide synthase promoter/enchacer activity by TGF-β1 in vascular smooth muscle cells. J. Biol. Chem. 271, 13776-13780.
26. Siesjö B. K. (1992) Pathophysiology and treatment of local cerebral ischemia. J. Neurosurg. 77, 169-184.
27. Simmons M. L. and Murphy S. (1993) Cytokines regulate L-arginine-dependent cyclic GMP production in rat glial cells. Eur. J. Neurosci. 5, 825-831.
28. Vodovotz Y., Bogdan C., Paik J., Xie Q.-W., and Nathan C. (1993) Mechanisms of suppression of macrophage nitric oxide release by TGFβ. J. Exp. Med. 178, 605-613.
29. Wallace M. N. and Bislund S. K. (1994) NADPH-diaphorase activity in activated astrocytes represents inducible nitric oxide synthase. Neuroscience 59, 905-919.