Synthesis and nicotinic binding studies on enantiopure pinnamine variants with an 8-azabicyclo[3.2.1]octane moiety

Pharmazie

Volumn 58, Issue 5, 2003, Pages 295-299

  Schwarz, S ^a   Kampchen T ^a   Tilotta, M C ^b   Gundisch D ^b   Seitz, Gunther ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 ETHYL 12 METHYL 6 OXA 12 AZATRICYCLO[7.2.1.0]DODEC 4 EN 3 ONE; 8 AZABICYCLO[3.2.1]OCTANE; 9 AZABICYCLO[4.2.1]NONANE; ALKALOID DERIVATIVE; ECGONINE METHYL ESTER; FERRUGININE; HETEROCYCLIC COMPOUND; IMINE; LIGAND; LITHIUM ION; MARINE TOXIN; N TERT BUTYLBUTYRALDIMIN; NICOTINIC RECEPTOR; PINNAMINE; PINNAMINE DERIVATIVE; PYRANOTROPANE DERIVATIVE; RECEPTOR SUBTYPE; TROPANE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING KINETICS; CHIRALITY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYCLIZATION; DIASTEREOISOMER; DRUG CONFORMATION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; ENANTIOMER; IN VITRO STUDY; NONHUMAN; PHARMACOPHORE; POLYMERIZATION; RAT; RECEPTOR AFFINITY; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

ANIMALS; AZA COMPOUNDS; BRAIN; CYCLOOCTANES; DRUG DESIGN; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC; SPECTROPHOTOMETRY, INFRARED; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037568179     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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