메뉴 건너뛰기




Volumn 20, Issue 6, 2003, Pages 465-476

Memantine

Author keywords

[No Author keywords available]

Indexed keywords

DONEPEZIL; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

EID: 0037565267     PISSN: 1170229X     EISSN: None     Source Type: Journal    
DOI: 10.2165/00002512-200320060-00005     Document Type: Review
Times cited : (72)

References (56)
  • 1
    • 0033604631 scopus 로고    scopus 로고
    • Treatment of Alzheimer's disease
    • Nov 25
    • Mayeux R, Sano M. Treatment of Alzheimer's disease. N Engl J Med 1999 Nov 25; 341: 1670-9
    • (1999) N Engl J Med , vol.341 , pp. 1670-1679
    • Mayeux, R.1    Sano, M.2
  • 2
    • 0030050262 scopus 로고    scopus 로고
    • Vascular dementia
    • Jan 27
    • Amar K, Wilcock G. Vascular dementia. Br Med J 1996 Jan 27; 312: 227-31
    • (1996) Br Med J , vol.312 , pp. 227-231
    • Amar, K.1    Wilcock, G.2
  • 3
    • 0032814109 scopus 로고    scopus 로고
    • Cerebrovascular dementia: Pathophysiology, diagnosis and treatment
    • Jul
    • Erkinjuntti T. Cerebrovascular dementia: pathophysiology, diagnosis and treatment. CNS Drugs 1999 Jul; 12: 35-48
    • (1999) CNS Drugs , vol.12 , pp. 35-48
    • Erkinjuntti, T.1
  • 4
    • 0032950029 scopus 로고    scopus 로고
    • The glutamatergic system and neurodegeneration in dementia: Preventive strategies in Alzheimer's disease
    • Cacabelos R, Takeda M, Winblad B. The glutamatergic system and neurodegeneration in dementia: preventive strategies in Alzheimer's disease. Int J Geriatr Psychiatry 1999; 14 (1): 3-47
    • (1999) Int J Geriatr Psychiatry , vol.14 , Issue.1 , pp. 3-47
    • Cacabelos, R.1    Takeda, M.2    Winblad, B.3
  • 5
    • 0017511803 scopus 로고
    • Effects of intravenous administration of memantine in Parkinsonian patients
    • Fischer P-A, Jacobi P, Schneider E, et al. Effects of intravenous administration of memantine in Parkinsonian patients (in German]. Arzneimittelforschung 1977; 27 (II) (7): 1487-9
    • (1977) Arzneimittelforschung , vol.27 , Issue.2-7 , pp. 1487-1489
    • Fischer, P.-A.1    Jacobi, P.2    Schneider, E.3
  • 6
    • 0025871272 scopus 로고
    • Efficacy and tolerability of memantine in patients with dementia syndrome: A double-blind, placebo controlled trial
    • Aug
    • Ditzler K. Efficacy and tolerability of memantine in patients with dementia syndrome: a double-blind, placebo controlled trial. Arzneimittelforschung 1991 Aug; 41 (8): 773-80
    • (1991) Arzneimittelforschung , vol.41 , Issue.8 , pp. 773-780
    • Ditzler, K.1
  • 7
    • 0026770756 scopus 로고
    • Memantine in the treatment of mild to moderate dementia syndrome: A double-blind placebo-controlled study
    • Jul
    • Görtelmeyer R, Erbler H. Memantine in the treatment of mild to moderate dementia syndrome: a double-blind placebo-controlled study. Arzneimittelforschung 1992 Jul; 42 (7): 904-13
    • (1992) Arzneimittelforschung , vol.42 , Issue.7 , pp. 904-913
    • Görtelmeyer, R.1    Erbler, H.2
  • 8
    • 0001465499 scopus 로고
    • Clinical and behavioural evaluation in long-term care patients with mild to moderate dementia under memantine treatment
    • Pantev M, Ritter R, Görtelmeyer R. Clinical and behavioural evaluation in long-term care patients with mild to moderate dementia under memantine treatment. Zeitschrift Fur Gerontopsychologie Und -Psychiatrie 1993; 6: 103-17
    • (1993) Zeitschrift Fur Gerontopsychologie Und -Psychiatrie , vol.6 , pp. 103-117
    • Pantev, M.1    Ritter, R.2    Görtelmeyer, R.3
  • 9
    • 0019981668 scopus 로고
    • Memantine and neurogenic bladder dysfunction in spastic conditions
    • Grossmann W, Schütz W. Memantine and neurogenic bladder dysfunction in spastic conditions (in German). Arzneimittelforschung 1982; 32 (II) (10): 1273-6
    • (1982) Arzneimittelforschung , vol.32 , Issue.2-10 , pp. 1273-1276
    • Grossmann, W.1    Schütz, W.2
  • 10
    • 0019990879 scopus 로고
    • Use of symptomatic therapy with memantine in cerebral coma. I. Correlation of coma stages and EEG spectral patterns
    • Miltner FO. Use of symptomatic therapy with memantine in cerebral coma. I. Correlation of coma stages and EEG spectral patterns (in German). Arzneimittelforschung 1982; 32 (10): 1268-70
    • (1982) Arzneimittelforschung , vol.32 , Issue.10 , pp. 1268-1270
    • Miltner, F.O.1
  • 11
    • 0036045137 scopus 로고    scopus 로고
    • Glutamate receptors as a target for Alzheimer's disease - Are clinical results supporting the hope?
    • Winblad B, Möbius HJ, Stöffler A. Glutamate receptors as a target for Alzheimer's disease - are clinical results supporting the hope? J Neural Transm 2002; 62 Suppl.: 217-25
    • (2002) J Neural Transm , Issue.62 SUPPL. , pp. 217-225
    • Winblad, B.1    Möbius, H.J.2    Stöffler, A.3
  • 12
    • 0036451888 scopus 로고    scopus 로고
    • Non-cholinergic strategies for treating and preventing Alzheimer's disease
    • Doraiswamy PM. Non-cholinergic strategies for treating and preventing Alzheimer's disease. CNS Drugs 2002; 16 (12): 811-24
    • (2002) CNS Drugs , vol.16 , Issue.12 , pp. 811-824
    • Doraiswamy, P.M.1
  • 13
    • 0023897040 scopus 로고
    • Treatment of impaired cerebral function in psychogeriatric patients with memantine - Results of a phase II double-blind study
    • May
    • Ambrozi L, Danielczyk W. Treatment of impaired cerebral function in psychogeriatric patients with memantine - results of a phase II double-blind study. Pharmacopsychiatry 1988 May; 21 (3): 144-6
    • (1988) Pharmacopsychiatry , vol.21 , Issue.3 , pp. 144-146
    • Ambrozi, L.1    Danielczyk, W.2
  • 14
    • 0026564448 scopus 로고
    • Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: Therapeutic advantage against NMDA receptor-mediated neurotoxicity
    • Nov
    • Chen H-S, Pellegrini JW, Aggarwal SK, et al. Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity. J Neurosci 1992 Nov; 12 (11): 4427-36
    • (1992) J Neurosci , vol.12 , Issue.11 , pp. 4427-4436
    • Chen, H.-S.1    Pellegrini, J.W.2    Aggarwal, S.K.3
  • 15
    • 0031034905 scopus 로고    scopus 로고
    • Mechanism of memantine block of NMDA-activated channels in rat retinal ganglion cells: Uncompetitive antagonism
    • Feb 15
    • Chen H-S, Lipton SA. Mechanism of memantine block of NMDA-activated channels in rat retinal ganglion cells: uncompetitive antagonism. J Physiol 1997 Feb 15; 499 (Pt 1): 27-46
    • (1997) J Physiol , vol.499 , Issue.PART 1 , pp. 27-46
    • Chen, H.-S.1    Lipton, S.A.2
  • 16
    • 0027997668 scopus 로고
    • Suppression by memantine and amantadine of synaptic excitation intrastriatally evoked in rat neostriatal slices
    • Nov 21
    • Rohrbacher J, Bijak M, Misgeld U. Suppression by memantine and amantadine of synaptic excitation intrastriatally evoked in rat neostriatal slices. Neurosci Lett 1994 Nov 21; 182 (1): 95-8
    • (1994) Neurosci Lett , vol.182 , Issue.1 , pp. 95-98
    • Rohrbacher, J.1    Bijak, M.2    Misgeld, U.3
  • 17
    • 0029971255 scopus 로고    scopus 로고
    • Comparative patch-clamp studies with freshly dissociated rat hippocampal and striatal neurons on the NMDA receptor antagonistic effects of amantadine and memantine
    • Mar
    • Parsons CG, Panchenko VA, Pinchenko VO, et al. Comparative patch-clamp studies with freshly dissociated rat hippocampal and striatal neurons on the NMDA receptor antagonistic effects of amantadine and memantine. Eur J Neurosci 1996 Mar; 8 (3): 446-54
    • (1996) Eur J Neurosci , vol.8 , Issue.3 , pp. 446-454
    • Parsons, C.G.1    Panchenko, V.A.2    Pinchenko, V.O.3
  • 18
    • 0030029425 scopus 로고    scopus 로고
    • Effects of memantine and MK-801 on NMDA-induced currents in cultured neurones and on synaptic transmission and LTP in area CA1 of rat hippocampal slices
    • Feb
    • Frankiewicz T, Potier B, Bashir ZI, et al. Effects of memantine and MK-801 on NMDA-induced currents in cultured neurones and on synaptic transmission and LTP in area CA1 of rat hippocampal slices. Br J Pharmacol 1996 Feb; 117 (4): 689-97
    • (1996) Br J Pharmacol , vol.117 , Issue.4 , pp. 689-697
    • Frankiewicz, T.1    Potier, B.2    Bashir, Z.I.3
  • 19
    • 0032190611 scopus 로고    scopus 로고
    • Interaction of memantine and amantadine with agonist-unbound NMDA-receptor channels in acutely isolated rat hippocampal neurons
    • Oct 1
    • Sobolevsky AI, Koshelev SG, Khodorov BI. Interaction of memantine and amantadine with agonist-unbound NMDA-receptor channels in acutely isolated rat hippocampal neurons. J Physiol 1998 Oct 1; 512 (Pt 1): 47-60
    • (1998) J Physiol , vol.512 , Issue.PART 1 , pp. 47-60
    • Sobolevsky, A.I.1    Koshelev, S.G.2    Khodorov, B.I.3
  • 20
    • 0032810628 scopus 로고    scopus 로고
    • Memantine restores long term potentiation impaired by tonic N-methyl-D-aspartate (NMDA) receptor activation following reduction of Mg2+ in hippocampal slices
    • Sep
    • Frankiewicz T, Parsons CG. Memantine restores long term potentiation impaired by tonic N-methyl-D-aspartate (NMDA) receptor activation following reduction of Mg2+ in hippocampal slices. Neuropharmacology 1999 Sep; 38 (9): 1253-9
    • (1999) Neuropharmacology , vol.38 , Issue.9 , pp. 1253-1259
    • Frankiewicz, T.1    Parsons, C.G.2
  • 21
    • 0031020529 scopus 로고    scopus 로고
    • Trapping channel block of NMDA-activated responses by amantadine and memantine
    • Jan
    • Blanpied TA, Boeckman FA, Aizenman E, et al. Trapping channel block of NMDA-activated responses by amantadine and memantine. J Neurophysiol 1997 Jan; 77 (1): 309-23
    • (1997) J Neurophysiol , vol.77 , Issue.1 , pp. 309-323
    • Blanpied, T.A.1    Boeckman, F.A.2    Aizenman, E.3
  • 22
    • 0024344256 scopus 로고
    • Memantine is a potent blocker of N-methyl-D-aspartate (NMDA) receptor channels
    • Aug 3
    • Bormann J. Memantine is a potent blocker of N-methyl-D-aspartate (NMDA) receptor channels. Eur J Pharmacol 1989 Aug 3; 166 (3): 591-2
    • (1989) Eur J Pharmacol , vol.166 , Issue.3 , pp. 591-592
    • Bormann, J.1
  • 23
    • 0027731677 scopus 로고
    • Patch clamp studies on the kinetics and selectivity of N-methyl-D-aspartate receptor antagonism by memantine (1-amino-3,5- dimethyladamantan)
    • Dec
    • Parsons CG, Gruner R, Rozental J, et al. Patch clamp studies on the kinetics and selectivity of N-methyl-D-aspartate receptor antagonism by memantine (1-amino-3,5- dimethyladamantan). Neuropharmacology 1993 Dec; 32 (12): 1337-50
    • (1993) Neuropharmacology , vol.32 , Issue.12 , pp. 1337-1350
    • Parsons, C.G.1    Gruner, R.2    Rozental, J.3
  • 24
    • 0030497661 scopus 로고    scopus 로고
    • Apparent independent action of nimodipine and glutamate antagonists to protect cultured neurons against glutamate-induced damage
    • Krieglstein J, Lippert K, Pöch G. Apparent independent action of nimodipine and glutamate antagonists to protect cultured neurons against glutamate-induced damage. Neuropharmacology 1996; 35 (No. 12): 1737-42
    • (1996) Neuropharmacology , vol.35 , Issue.12 , pp. 1737-1742
    • Krieglstein, J.1    Lippert, K.2    Pöch, G.3
  • 25
    • 0025801643 scopus 로고
    • Memantine is highly potent in protecting cortical cultures against excitotoxic cell death evoked by glutamate and N-methyl-D-aspartate
    • Jun 6
    • Erdö SL, Schafer M. Memantine is highly potent in protecting cortical cultures against excitotoxic cell death evoked by glutamate and N-methyl-D-aspartate. Eur J Pharmacol 1991 Jun 6; 198 (2-3): 215-7
    • (1991) Eur J Pharmacol , vol.198 , Issue.2-3 , pp. 215-217
    • Erdö, S.L.1    Schafer, M.2
  • 26
    • 0027246262 scopus 로고
    • NMDA receptor-mediated glutamate toxicity of cultured cerebellar, cortical and mesencephalic neurons: Neuroprotective properties of amantadine and memantine
    • Weller M, Finiels-Marlier F, Paul SM. NMDA receptor-mediated glutamate toxicity of cultured cerebellar, cortical and mesencephalic neurons: neuroprotective properties of amantadine and memantine. Brain Res 1993; 613: 143-8
    • (1993) Brain Res , vol.613 , pp. 143-148
    • Weller, M.1    Finiels-Marlier, F.2    Paul, S.M.3
  • 27
    • 0027474163 scopus 로고
    • Delayed administration of memantine prevents N-methyl-D-aspartate receptor-mediated neurotoxicity
    • Apr
    • Pellegrini JW, Lipton SA. Delayed administration of memantine prevents N-methyl-D-aspartate receptor-mediated neurotoxicity. Ann Neurol 1993 Apr; 33 (4): 403-7
    • (1993) Ann Neurol , vol.33 , Issue.4 , pp. 403-407
    • Pellegrini, J.W.1    Lipton, S.A.2
  • 28
    • 0035933672 scopus 로고    scopus 로고
    • The N-methyl-D-aspartate receptor channel blockers memantine, MRZ 2/579 and other amino-alkyl-cyclohexanes antagonise 5-HT(3) receptor currents in cultured HEK-293 and N1E-115 cell systems in a non-competitive manner
    • Jun 22
    • Rammes G, Rupprecht R, Ferrari U, et al. The N-methyl-D-aspartate receptor channel blockers memantine, MRZ 2/579 and other amino-alkyl-cyclohexanes antagonise 5-HT(3) receptor currents in cultured HEK-293 and N1E-115 cell systems in a non-competitive manner. Neurosci Lett 2001 Jun 22; 306 (1-2): 81-4
    • (2001) Neurosci Lett , vol.306 , Issue.1-2 , pp. 81-84
    • Rammes, G.1    Rupprecht, R.2    Ferrari, U.3
  • 29
    • 0031081014 scopus 로고    scopus 로고
    • Neuroprotection of acetylcholinergic basal forebrain neurons by memantine and neurokinin B
    • Feb
    • Wenk GL, Zajaczkowski W, Danysz W. Neuroprotection of acetylcholinergic basal forebrain neurons by memantine and neurokinin B. Behav Brain Res 1997 Feb; 83 (1-2): 129-33
    • (1997) Behav Brain Res , vol.83 , Issue.1-2 , pp. 129-133
    • Wenk, G.L.1    Zajaczkowski, W.2    Danysz, W.3
  • 30
    • 0035903064 scopus 로고    scopus 로고
    • Neuroprotection by memantine, a non-competitive NMDA receptor antagonist after traumatic brain injury in rats
    • Aug 17
    • Rao VLR, Dogan A, Todd KG, et al. Neuroprotection by memantine, a non-competitive NMDA receptor antagonist after traumatic brain injury in rats. Brain Res 2001 Aug 17; 911 (1): 96-100
    • (2001) Brain Res , vol.911 , Issue.1 , pp. 96-100
    • Rao, V.L.R.1    Dogan, A.2    Todd, K.G.3
  • 31
    • 0034538373 scopus 로고    scopus 로고
    • Reduction of edema and infarction by memantine and MK-801 after focal cerebral ischaemia and reperfusion in rat
    • Görgülü A, Kins T, Çobanoglu S, et al. Reduction of edema and infarction by memantine and MK-801 after focal cerebral ischaemia and reperfusion in rat. Acta Neurochir (Wien) 2000; 142 (11): 1287-92
    • (2000) Acta Neurochir (Wien) , vol.142 , Issue.11 , pp. 1287-1292
    • Görgülü, A.1    Kins, T.2    Çobanoglu, S.3
  • 32
    • 0032696663 scopus 로고    scopus 로고
    • Protective effects of memantine against ischemia-reperfusion injury in spontaneously hypertensive rats
    • Dogan A, Eras MA, Rao VLR, et al. Protective effects of memantine against ischemia-reperfusion injury in spontaneously hypertensive rats. Acta Neurochir (Wien) 1999; 141 (10): 1107-13
    • (1999) Acta Neurochir (Wien) , vol.141 , Issue.10 , pp. 1107-1113
    • Dogan, A.1    Eras, M.A.2    Rao, V.L.R.3
  • 33
    • 0024988908 scopus 로고
    • Neuroprotective effect of memantine demonstrated in vivo and in vitro
    • Aug 21
    • Seif el Nasr M, Peruche B, Rossberg C, et al. Neuroprotective effect of memantine demonstrated in vivo and in vitro. Eur J Pharmacol 1990 Aug 21; 185 (1): 19-24
    • (1990) Eur J Pharmacol , vol.185 , Issue.1 , pp. 19-24
    • Seif El Nasr, M.1    Peruche, B.2    Rossberg, C.3
  • 34
    • 0029414737 scopus 로고
    • Memantine prevents progressive functional neurodegeneration in rats
    • Heim C, Sontag KH. Memantine prevents progressive functional neurodegeneration in rats. J Neural Transm 1995; 46 Suppl.: 117-30
    • (1995) J Neural Transm , Issue.46 SUPPL. , pp. 117-130
    • Heim, C.1    Sontag, K.H.2
  • 35
    • 0033019327 scopus 로고    scopus 로고
    • Neuroprotection by the NMDA receptor-associated open-channel blocker memantine in a photothrombotic model of cerebral focal ischemia in neonatal rat
    • Jun 30
    • Stieg PE, Sathi S, Warach S, et al. Neuroprotection by the NMDA receptor-associated open-channel blocker memantine in a photothrombotic model of cerebral focal ischemia in neonatal rat. Eur J Pharmacol 1999 Jun 30; 375 (1-3): 115-20
    • (1999) Eur J Pharmacol , vol.375 , Issue.1-3 , pp. 115-120
    • Stieg, P.E.1    Sathi, S.2    Warach, S.3
  • 36
    • 0026706896 scopus 로고
    • Memantine prevents quinolinic acid-induced hippocampal damage
    • Sep 4
    • Keilhoff G, Wolf G. Memantine prevents quinolinic acid-induced hippocampal damage. Eur J Pharmacol 1992 Sep 4; 219 (3): 451-4
    • (1992) Eur J Pharmacol , vol.219 , Issue.3 , pp. 451-454
    • Keilhoff, G.1    Wolf, G.2
  • 37
    • 0034764208 scopus 로고    scopus 로고
    • The neuroprotective agent memantine induces brain-derived neurotrophic factor and trkB receptor expression in rat brain
    • Sep
    • Marvanová M, Lakso M, Pirhonen J, et al. The neuroprotective agent memantine induces brain-derived neurotrophic factor and trkB receptor expression in rat brain. Mol Cell Neurosci 2001 Sep; 18 (3): 247-58
    • (2001) Mol Cell Neurosci , vol.18 , Issue.3 , pp. 247-258
    • Marvanová, M.1    Lakso, M.2    Pirhonen, J.3
  • 38
    • 0033529785 scopus 로고    scopus 로고
    • Influence of the N-methyl-D-aspartate antagonist memantine on human motor cortex excitability
    • Aug 6
    • Schwenkreis P, Witscher K, Janssen F, et al. Influence of the N-methyl-D-aspartate antagonist memantine on human motor cortex excitability. Neurosci Lett 1999 Aug 6; 270 (3): 137-40
    • (1999) Neurosci Lett , vol.270 , Issue.3 , pp. 137-140
    • Schwenkreis, P.1    Witscher, K.2    Janssen, F.3
  • 39
    • 0031054229 scopus 로고    scopus 로고
    • The NMDA antagonist memantine impairs classical eyeblink conditioning in humans
    • Mar 7
    • Schugens MM, Egerter R, Daum I, et al. The NMDA antagonist memantine impairs classical eyeblink conditioning in humans. Neurosci Lett 1997 Mar 7; 224 (1): 57-60
    • (1997) Neurosci Lett , vol.224 , Issue.1 , pp. 57-60
    • Schugens, M.M.1    Egerter, R.2    Daum, I.3
  • 40
    • 0030026553 scopus 로고    scopus 로고
    • The use of diurnal vigilance changes in the EEG to verify vigilance-enhancing effects of memantine in a clinical pharmacological study
    • Schulz H, Jobert M, Coppola R, et al. The use of diurnal vigilance changes in the EEG to verify vigilance-enhancing effects of memantine in a clinical pharmacological study. Neuropsychobiology 1996; 33 (1): 32-40
    • (1996) Neuropsychobiology , vol.33 , Issue.1 , pp. 32-40
    • Schulz, H.1    Jobert, M.2    Coppola, R.3
  • 41
    • 0035113635 scopus 로고    scopus 로고
    • Effects of pharmacologically induced changes in NMDA-receptor activity on long-term memory in humans
    • Rammsayer TH. Effects of pharmacologically induced changes in NMDA-receptor activity on long-term memory in humans. Learn Mem 2001; 8 (1): 20-5
    • (2001) Learn Mem , vol.8 , Issue.1 , pp. 20-25
    • Rammsayer, T.H.1
  • 43
    • 0034635589 scopus 로고    scopus 로고
    • No interaction of memantine with acetylcholinesterase inhibitors approved for clinical use
    • Feb 11
    • Wenk GL, Quack G, Moebius HJ, et al. No interaction of memantine with acetylcholinesterase inhibitors approved for clinical use. Life Sci 2000 Feb 11; 66 (12): 1079-83
    • (2000) Life Sci , vol.66 , Issue.12 , pp. 1079-1083
    • Wenk, G.L.1    Quack, G.2    Moebius, H.J.3
  • 45
    • 0037417238 scopus 로고    scopus 로고
    • A randomized, placebo-controlled study of memantine, an uncompetitive NMDA antagonist, in patients with moderate to severe Alzheimer's disease
    • Reisberg B, Doody R, Stöffler A, et al. A randomized, placebo-controlled study of memantine, an uncompetitive NMDA antagonist, in patients with moderate to severe Alzheimer's disease. N Engl J Med 2003; 348: 1333-41
    • (2003) N Engl J Med , vol.348 , pp. 1333-1341
    • Reisberg, B.1    Doody, R.2    Stöffler, A.3
  • 46
    • 0038529086 scopus 로고    scopus 로고
    • Long-term treatment with the NMDA antagonist memantine: Results of a 24-week, open-label extension study in moderately severe to severe Alzheimer's disease
    • Stockholm July 20-25
    • Reisberg B, Möbius HJ, Stöffler A, et al. Long-term treatment with the NMDA antagonist memantine: results of a 24-week, open-label extension study in moderately severe to severe Alzheimer's disease [abstract]. 8th International Conference on Alzheimer's Disease and Related Disorders, Stockholm July 20-25 2000
    • (2000) 8th International Conference on Alzheimer's Disease and Related Disorders
    • Reisberg, B.1    Möbius, H.J.2    Stöffler, A.3
  • 47
    • 0037852643 scopus 로고    scopus 로고
    • Long-term treatment with the NMDA antagonist, memantine: Results of a 24-week, open-label extension study in advanced Alzheimer's Disease [poster], Waikoloa Village, Hawaii Dec 9-13
    • Ferris SH, Schmidt F, Doody R, et al. Long-term treatment with the NMDA antagonist, memantine: results of a 24-week, open-label extension study in advanced Alzheimer's Disease [poster]. Annual Meeting of the American College of Neuropsychopharmacology, Waikoloa Village, Hawaii Dec 9-13 2001
    • (2001) Annual Meeting of the American College of Neuropsychopharmacology
    • Ferris, S.H.1    Schmidt, F.2    Doody, R.3
  • 48
    • 0032983786 scopus 로고    scopus 로고
    • Memantine in severe dementia: Results of the 9M-Best Study (benefit and efficacy in severely demented patients during treatment with memantine)
    • Feb
    • Winblad B, Poritis N. Memantine in severe dementia: results of the 9M-Best Study (benefit and efficacy in severely demented patients during treatment with memantine). Int J Geriatr Psychiatry 1999 Feb; 14 (2): 135-46
    • (1999) Int J Geriatr Psychiatry , vol.14 , Issue.2 , pp. 135-146
    • Winblad, B.1    Poritis, N.2
  • 49
    • 0036314492 scopus 로고    scopus 로고
    • Efficacy and safety of memantine in patients with mild to moderate vascular dementia: A randomized, placebo-controlled trial (MMM 300)
    • Jul
    • Orgogozo J-M, Rigaud A-S, Stöffler A, et al. Efficacy and safety of memantine in patients with mild to moderate vascular dementia: a randomized, placebo-controlled trial (MMM 300). Stroke 2002 Jul; 33 (7): 1834-9
    • (2002) Stroke , vol.33 , Issue.7 , pp. 1834-1839
    • Orgogozo, J.-M.1    Rigaud, A.-S.2    Stöffler, A.3
  • 50
    • 0036840767 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled multicentre study of memantine in mild to moderate vascular dementia (MMM500)
    • Nov
    • Wilcock G, Möbius HJ, Stöffler A. A double-blind, placebo-controlled multicentre study of memantine in mild to moderate vascular dementia (MMM500). Int Clin Psychopharmacol 2002 Nov; 17 (6): 297-305
    • (2002) Int Clin Psychopharmacol , vol.17 , Issue.6 , pp. 297-305
    • Wilcock, G.1    Möbius, H.J.2    Stöffler, A.3
  • 51
    • 0038529085 scopus 로고    scopus 로고
    • Memantine/ donepezil dual therapy is superior to placebo/donepezil therapy for treatment of moderate to severe Alzheimer's disease
    • abstract no. 1035
    • Farlow MR, Tariot PN, Grossberg GT, et al. Memantine/ donepezil dual therapy is superior to placebo/donepezil therapy for treatment of moderate to severe Alzheimer's disease [abstract no. 1035]. Neurology 2003; 60 Suppl. 1: A412
    • (2003) Neurology , Issue.60 SUPPL. 1
    • Farlow, M.R.1    Tariot, P.N.2    Grossberg, G.T.3
  • 52
    • 0037247048 scopus 로고    scopus 로고
    • Resource utilisation and cost analysis of memantine in patients with moderate to severe Alzheimer's disease
    • Wimo A, Winblad B, Stöffler A, et al. Resource utilisation and cost analysis of memantine in patients with moderate to severe Alzheimer's disease. Pharmacoeconomics 2003; 21 (5): 327-40
    • (2003) Pharmacoeconomics , vol.21 , Issue.5 , pp. 327-340
    • Wimo, A.1    Winblad, B.2    Stöffler, A.3
  • 53
    • 0000636319 scopus 로고    scopus 로고
    • Neuro-radiological findings and the magnitude of cognitive benefit by memantine treatment: A subgroup analysis of two placebo-controlled clinical trials in vascular dementia
    • Sep
    • Wilcock G, Stoeffler A, Sahin K, et al. Neuro-radiological findings and the magnitude of cognitive benefit by memantine treatment: a subgroup analysis of two placebo-controlled clinical trials in vascular dementia [abstract]. Ear Neuropsychopharmacol 2000 Sep; 10 Suppl. 3: S360
    • (2000) Ear Neuropsychopharmacol , Issue.10 SUPPL. 3
    • Wilcock, G.1    Stoeffler, A.2    Sahin, K.3
  • 54
    • 0037345885 scopus 로고    scopus 로고
    • Tolerability of memantine in combination with cholinesterase inhibitors in dementia therapy
    • Mar
    • Hartmann S, Möbius HJ. Tolerability of memantine in combination with cholinesterase inhibitors in dementia therapy. Int Clin Psychopharmacol 2003 Mar; 18 (2): 81-5
    • (2003) Int Clin Psychopharmacol , vol.18 , Issue.2 , pp. 81-85
    • Hartmann, S.1    Möbius, H.J.2
  • 55
    • 0038529089 scopus 로고    scopus 로고
    • Forest Laboratories. New study shows improved cognition relative to baseline for Alzheimer's patients treated with investigational memantine and donepezil (Accessed 17 Dec 2002) [media release]. 2002
    • Forest Laboratories. New study shows improved cognition relative to baseline for Alzheimer's patients treated with investigational memantine and donepezil (Accessed 17 Dec 2002) [media release]. 2002
  • 56
    • 0037852646 scopus 로고    scopus 로고
    • Forest Laboratories. Forest Laboratories submits New Drug Application for investigational Alzheimer's treatment memantine (Accessed 16 Apr 2002) [media release]. 2002
    • Forest Laboratories. Forest Laboratories submits New Drug Application for investigational Alzheimer's treatment memantine (Accessed 16 Apr 2002) [media release]. 2002


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.