메뉴 건너뛰기




Volumn 14, Issue 2, 2002, Pages 163-169

Congenital thrombophilia associated to obstetric complications

Author keywords

Activated protein C resistance; Factor V Leiden; Fetal loss; Hyperhomocysteinemia; MTHFR; Preeclampsia; Prothrombin G20210A; Thrombophilia

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ACTIVATED PROTEIN C; BLOOD CLOTTING FACTOR 5 LEIDEN; HOMOCYSTEINE; PROTHROMBIN;

EID: 0037541091     PISSN: 09295305     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1023293114529     Document Type: Review
Times cited : (16)

References (73)
  • 1
    • 0002116036 scopus 로고    scopus 로고
    • Hypercoagulable states
    • In: Hoffman R, Benz EJ Jr, Shattil SJ, Furie B, Cohen HJ, Silberstein LE, McGlave P (Eds.); Churchill Livingstone, Philadelphia
    • Bauer KM. Hypercoagulable states. In: Hoffman R, Benz EJ Jr, Shattil SJ, Furie B, Cohen HJ, Silberstein LE, McGlave P (Eds.). Hematology: Basic Principles and Practice. Churchill Livingstone, Philadelphia, 2000:2009-2039.
    • (2000) Hematology: Basic Principles and Practice , pp. 2009-2039
    • Bauer, K.M.1
  • 2
    • 0037532190 scopus 로고    scopus 로고
    • Current concepts of thrombosis: Prevalent trends for diagnosis and management
    • Bick R, Kaplan H. Current concepts of thrombosis: Prevalent trends for diagnosis and management. Med Clin North Am 1998;82:410-458.
    • (1998) Med Clin North Am , vol.82 , pp. 410-458
    • Bick, R.1    Kaplan, H.2
  • 3
    • 0033399349 scopus 로고    scopus 로고
    • Pathophysiological and clinical aspects of venous and arterial thrombosis
    • Hemker HC, Lévy-Toledano S. Pathophysiological and clinical aspects of venous and arterial thrombosis. Haemostasis 1999;29:76-99.
    • (1999) Haemostasis , vol.29 , pp. 76-99
    • Hemker, H.C.1    Lévy-Toledano, S.2
  • 4
    • 0016865511 scopus 로고
    • Proceedings: Inherited antithrombin III deficiency and thromboembolism
    • Egeberg O. Proceedings: Inherited antithrombin III deficiency and thromboembolism. Thromb Diath Haemorrh 1975;34:366.
    • (1975) Thromb Diath Haemorrh , vol.34 , pp. 366
    • Egeberg, O.1
  • 5
    • 0001820053 scopus 로고    scopus 로고
    • Approach to the thrombophilic patient
    • In: Colman RW, Hirsh J, Marder VJ, Clowes AW, George JN (Eds.); Philadelphia, Lippincott Williams & Wilkins
    • Middeldorp S, Büller HR, Prins MH, Hirsh J. Approach to the thrombophilic patient. In: Colman RW, Hirsh J, Marder VJ, Clowes AW, George JN (Eds.). Hemostasis and Thrombosis. Basic Principles and Clinical Practice. Philadelphia, Lippincott Williams & Wilkins, 2001:1085-1100.
    • (2001) Hemostasis and Thrombosis. Basic Principles and Clinical Practice , pp. 1085-1100
    • Middeldorp, S.1    Büller, H.R.2    Prins, M.H.3    Hirsh, J.4
  • 6
    • 0026298247 scopus 로고
    • Hipercoagulabilidad y estados trombofilicos
    • Páramo JA, Rocha E. Hipercoagulabilidad y estados trombofilicos. Sangre 1991;36:477-486.
    • (1991) Sangre , vol.36 , pp. 477-486
    • Páramo, J.A.1    Rocha, E.2
  • 7
    • 0027446268 scopus 로고
    • Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: Prediction of a cofactor to activated protein C
    • Dahlback B, Carlsson M, Svensson PJ. Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: Prediction of a cofactor to activated protein C. Proc Natl Acad Sci USA 1993;90:1004-1008.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1004-1008
    • Dahlback, B.1    Carlsson, M.2    Svensson, P.J.3
  • 8
    • 1842290346 scopus 로고    scopus 로고
    • Resistance to activated protein C caused by the factor V R506Q mutation is a common risk factor for venous thrombosis
    • Dahlback B. Resistance to activated protein C caused by the factor V R506Q mutation is a common risk factor for venous thrombosis. Thromb Haemostas 1997;78:483-489.
    • (1997) Thromb Haemostas , vol.78 , pp. 483-489
    • Dahlback, B.1
  • 9
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
    • Frosst P, Blom HJ, Milos R, et al. A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase. Nat Genet 1995;10:111-113.
    • (1995) Nat Genet , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3
  • 10
    • 0029850530 scopus 로고    scopus 로고
    • A common genetic variation in the 3-untraslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis
    • Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3-untraslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 1996;88:3698-3703.
    • (1996) Blood , vol.88 , pp. 3698-3703
    • Poort, S.R.1    Rosendaal, F.R.2    Reitsma, P.H.3    Bertina, R.M.4
  • 11
    • 0034161456 scopus 로고    scopus 로고
    • Role of hemostatic gene polymorphisms in venous and arterial thrombotic disease
    • Lane DA, Grant PJ. Role of hemostatic gene polymorphisms in venous and arterial thrombotic disease. Blood 2000;95:1517-1532.
    • (2000) Blood , vol.95 , pp. 1517-1532
    • Lane, D.A.1    Grant, P.J.2
  • 12
    • 0028029477 scopus 로고
    • Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation
    • Vandenbroucke J, Koster T, Briet E, Reitsma PH, Bertina RM, Rosendaal FR. Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation. Lancet 1994;344:1453-1457.
    • (1994) Lancet , vol.344 , pp. 1453-1457
    • Vandenbroucke, J.1    Koster, T.2    Briet, E.3    Reitsma, P.H.4    Bertina, R.M.5    Rosendaal, F.R.6
  • 13
    • 0030893834 scopus 로고    scopus 로고
    • Hypercoagulability in venous and arterial thrombosis
    • Thomas DP, Roberts HR. Hypercoagulability in venous and arterial thrombosis. Ann Intern Med 1997;126:638-644.
    • (1997) Ann Intern Med , vol.126 , pp. 638-644
    • Thomas, D.P.1    Roberts, H.R.2
  • 14
    • 0033519051 scopus 로고    scopus 로고
    • Venous thrombosis: A multicausal disease
    • Rosendaal FR. Venous thrombosis: A multicausal disease. Lancet 1999;353:1167-1173.
    • (1999) Lancet , vol.353 , pp. 1167-1173
    • Rosendaal, F.R.1
  • 16
    • 0033901546 scopus 로고    scopus 로고
    • Thrombophilia in pregnancy
    • Walker ID. Thrombophilia in pregnancy. J Clin Pathol 2000;53:573-580.
    • (2000) J Clin Pathol , vol.53 , pp. 573-580
    • Walker, I.D.1
  • 17
    • 0031765181 scopus 로고    scopus 로고
    • Inherited thrombophilia and pregnancy: The obstetric perspective
    • Bonnar J, Green R, Norris L. Inherited thrombophilia and pregnancy: The obstetric perspective. Seminars Thromb Hemostas 1998;24:49-53.
    • (1998) Seminars Thromb Hemostas , vol.24 , pp. 49-53
    • Bonnar, J.1    Green, R.2    Norris, L.3
  • 18
    • 0031733401 scopus 로고    scopus 로고
    • Acquired thrombophilia in pregnancy
    • Ballem P. Acquired thrombophilia in pregnancy. Seminars Thromb Hemostas 1998;24:41-47.
    • (1998) Seminars Thromb Hemostas , vol.24 , pp. 41-47
    • Ballem, P.1
  • 19
    • 0031594157 scopus 로고    scopus 로고
    • Factor V Q506 mutation (activated protein C resistance) associated with reduced intrapartum blood loss - A possible evolutionary selection mechanism
    • Lindqvisst PG, Svensson PJ, Dahlbäck B, Marsal K. Factor V Q506 mutation (activated protein C resistance) associated with reduced intrapartum blood loss - A possible evolutionary selection mechanism. Thromb Haemost 1998;79:69-73.
    • (1998) Thromb Haemost , vol.79 , pp. 69-73
    • Lindqvisst, P.G.1    Svensson, P.J.2    Dahlbäck, B.3    Marsal, K.4
  • 22
    • 0030743692 scopus 로고    scopus 로고
    • Factor V Leiden, C-T MTHFR polymorphism and genetic susceptibility to preeclampsia
    • Grandone E, Margaglione M, Calaizzo D, et al. Factor V Leiden, C-T MTHFR polymorphism and genetic susceptibility to preeclampsia. Thromb Haemost 1997;77:1052-1054.
    • (1997) Thromb Haemost , vol.77 , pp. 1052-1054
    • Grandone, E.1    Margaglione, M.2    Calaizzo, D.3
  • 23
    • 0033868908 scopus 로고    scopus 로고
    • Do placental lesions reflect thrombophilia state in women with adverse pregnancy outcome?
    • Mousa HA, Alfiveric Z. Do placental lesions reflect thrombophilia state in women with adverse pregnancy outcome? Hum Reprod 2000;15:1830-1833.
    • (2000) Hum Reprod , vol.15 , pp. 1830-1833
    • Mousa, H.A.1    Alfiveric, Z.2
  • 25
    • 0038546248 scopus 로고    scopus 로고
    • Thrombophilia-associated pregnancy wastage
    • Blumenfeld Z, Brenner B. Thrombophilia-associated pregnancy wastage. Fertil Steril 1999;353:1258-1265.
    • (1999) Fertil Steril , vol.353 , pp. 1258-1265
    • Blumenfeld, Z.1    Brenner, B.2
  • 26
    • 0034049238 scopus 로고    scopus 로고
    • High prevalence of hemostatic abnormalities in women with a history of severe preeclampsia
    • Huisjes AJ, Franx A, Bruinse HW. High prevalence of hemostatic abnormalities in women with a history of severe preeclampsia. Am J Obstet Gynecol 2000;182:989-990.
    • (2000) Am J Obstet Gynecol , vol.182 , pp. 989-990
    • Huisjes, A.J.1    Franx, A.2    Bruinse, H.W.3
  • 27
    • 0033531184 scopus 로고    scopus 로고
    • Increased frequency of genetic thrombophilia in women with complications of pregnancy
    • Kupferminc MJ, Eldor A, Steinman N, et al. Increased frequency of genetic thrombophilia in women with complications of pregnancy. N Eng J Med 1999;340:9-13.
    • (1999) N Eng J Med , vol.340 , pp. 9-13
    • Kupferminc, M.J.1    Eldor, A.2    Steinman, N.3
  • 29
    • 0034668897 scopus 로고    scopus 로고
    • Incidence of the factor V Leiden-mutation, coagulation inhibitor deficiency, and elevated antiphospholipid-antibodies in patients with preeclampsia or HELLP-syndrome
    • Von Tempelhoff GF, Heilmann L, Spanuth E, Kunzmann E, Hommel G. Incidence of the factor V Leiden-mutation, coagulation inhibitor deficiency, and elevated antiphospholipid-antibodies in patients with preeclampsia or HELLP-syndrome. Thromb Res 2000;100:363-365.
    • (2000) Thromb Res , vol.100 , pp. 363-365
    • Von Tempelhoff, G.F.1    Heilmann, L.2    Spanuth, E.3    Kunzmann, E.4    Hommel, G.5
  • 30
    • 0033932801 scopus 로고    scopus 로고
    • Maternal and neonatal outcome of preeclampsia pregnancies: The potential roles of factor V Leiden mutation and 5,10 methylenetetrahydrofolate reductase
    • Rigo J Jr, Nagy B, Fintor L, et al. Maternal and neonatal outcome of preeclampsia pregnancies: The potential roles of factor V Leiden mutation and 5,10 methylenetetrahydrofolate reductase. Hypertens Pregnancy 2000;19:163-172.
    • (2000) Hypertens Pregnancy , vol.19 , pp. 163-172
    • Rigo J., Jr.1    Nagy, B.2    Fintor, L.3
  • 31
    • 0029999583 scopus 로고    scopus 로고
    • The factor V Leiden mutation may predispose women to severe preeclampsia
    • Dizon-Townson DS, Nelson LM, Easton K, Ward K. The factor V Leiden mutation may predispose women to severe preeclampsia. Am J Obstet Gynecol 1996;175:902-905.
    • (1996) Am J Obstet Gynecol , vol.175 , pp. 902-905
    • Dizon-Townson, D.S.1    Nelson, L.M.2    Easton, K.3    Ward, K.4
  • 32
    • 0033000764 scopus 로고    scopus 로고
    • High prevalence of hemostatic abnormalities in women with a history of severe preeclampsia
    • Van Pampus MG, Dekker GA, Wolf H, et al. High prevalence of hemostatic abnormalities in women with a history of severe preeclampsia. Am J Obstet Gynecol 1999;180:989-990.
    • (1999) Am J Obstet Gynecol , vol.180 , pp. 989-990
    • Van Pampus, M.G.1    Dekker, G.A.2    Wolf, H.3
  • 33
    • 0032978344 scopus 로고    scopus 로고
    • Factor V Leiden and thermolabile methylenetetrahydrofolate reductase gene variants in an east anglian preeclampsia cohort
    • O'Shaughnessy KM, Fu B, Ferraro F, Lewis I, Downing S, Morris NH. Factor V Leiden and thermolabile methylenetetrahydrofolate reductase gene variants in an east anglian preeclampsia cohort. Hypertension 1999;33:1338-1341.
    • (1999) Hypertension , vol.33 , pp. 1338-1341
    • O'Shaughnessy, K.M.1    Fu, B.2    Ferraro, F.3    Lewis, I.4    Downing, S.5    Morris, N.H.6
  • 34
    • 0034924655 scopus 로고    scopus 로고
    • Maternal and fetal inherited thrombophilias are not related to the development of severe preeclampsia
    • Livingston JC, Barton JR, Park V, Haddad B, Phillips O, Sibai BM. Maternal and fetal inherited thrombophilias are not related to the development of severe preeclampsia. Am J Obstet Gynecol 2001;185:153-157.
    • (2001) Am J Obstet Gynecol , vol.185 , pp. 153-157
    • Livingston, J.C.1    Barton, J.R.2    Park, V.3    Haddad, B.4    Phillips, O.5    Sibai, B.M.6
  • 35
    • 0033431657 scopus 로고    scopus 로고
    • The factor V Leiden mutation is not a common cause of pregnancy-induced hypertension in Japan
    • Kobashi G, Yamada H, Asano T, et al. The factor V Leiden mutation is not a common cause of pregnancy-induced hypertension in Japan. Sem Thromb Hemost 1999;25:487-489.
    • (1999) Sem Thromb Hemost , vol.25 , pp. 487-489
    • Kobashi, G.1    Yamada, H.2    Asano, T.3
  • 36
    • 0035159048 scopus 로고    scopus 로고
    • The Glasgow Outcome, APCR and Lipid (GOAL) pregnancy study: Significance of pregnancy associated activated protein C resistance
    • Clark P, Sattar N, Walker ID, Greer IA. The Glasgow Outcome, APCR and Lipid (GOAL) pregnancy study: Significance of pregnancy associated activated protein C resistance. Thromb Haemost 2001;85:30-35.
    • (2001) Thromb Haemost , vol.85 , pp. 30-35
    • Clark, P.1    Sattar, N.2    Walker, I.D.3    Greer, I.A.4
  • 37
    • 0036021465 scopus 로고    scopus 로고
    • Mutations in the factor V, prothrombin and MTHFR genes are nor risk factors for recurrent fetal loss
    • Dilley A, Benito C, Hooper WC, et al. Mutations in the factor V, prothrombin and MTHFR genes are nor risk factors for recurrent fetal loss. J Matern Fetal Neonatal Med 2002;11:176-182.
    • (2002) J Matern Fetal Neonatal Med , vol.11 , pp. 176-182
    • Dilley, A.1    Benito, C.2    Hooper, W.C.3
  • 38
    • 0030064905 scopus 로고    scopus 로고
    • Second-trimester pregnancy loss is associated with activated protein C resistance
    • Rai R, Regan L, Hadely E, Dave M, Cohen H. Second-trimester pregnancy loss is associated with activated protein C resistance. Br J Haematol 1996;92:489-490.
    • (1996) Br J Haematol , vol.92 , pp. 489-490
    • Rai, R.1    Regan, L.2    Hadely, E.3    Dave, M.4    Cohen, H.5
  • 39
    • 0037532193 scopus 로고    scopus 로고
    • Increased fetal loss in women with heritable thrombophilia
    • Preston FE, Rosendaal FR, Walker ID, et al. Increased fetal loss in women with heritable thrombophilia. Lancet 1996;75:387-390.
    • (1996) Lancet , vol.75 , pp. 387-390
    • Preston, F.E.1    Rosendaal, F.R.2    Walker, I.D.3
  • 40
    • 0033973640 scopus 로고    scopus 로고
    • Activated protein C resistance and factor V Leiden mutation can be associated with first-as well as second trimester recurrent pregnancy loss
    • Younis JS, Brenner B, Ohel G, Tal J, Lanir N, Ben-Ami M. Activated protein C resistance and factor V Leiden mutation can be associated with first-as well as second trimester recurrent pregnancy loss. Am J Reprod Immunol 2000;43:31-35.
    • (2000) Am J Reprod Immunol , vol.43 , pp. 31-35
    • Younis, J.S.1    Brenner, B.2    Ohel, G.3    Tal, J.4    Lanir, N.5    Ben-Ami, M.6
  • 41
    • 0030928377 scopus 로고    scopus 로고
    • Factor V Leiden is associated with repeated and recurrent unexplained fetal losses
    • Grandone E, Margagliane M, Calazzio D, et al. Factor V Leiden is associated with repeated and recurrent unexplained fetal losses. Thromb Haemost 1997;77:822-824.
    • (1997) Thromb Haemost , vol.77 , pp. 822-824
    • Grandone, E.1    Margagliane, M.2    Calazzio, D.3
  • 42
    • 0032525869 scopus 로고    scopus 로고
    • Factor V Leiden mutation as a risk factor for recurrent pregnancy loss
    • Ridker PM, Miletich JP, Buring JE, et al. Factor V Leiden mutation as a risk factor for recurrent pregnancy loss. Ann Intern Med 1998;128:1000-1003.
    • (1998) Ann Intern Med , vol.128 , pp. 1000-1003
    • Ridker, P.M.1    Miletich, J.P.2    Buring, J.E.3
  • 43
    • 0017284939 scopus 로고
    • The pathogenesis of coronary artery disease. A possible role for methionine metabolism
    • Wilcken DEL, Wilcken B. The pathogenesis of coronary artery disease. A possible role for methionine metabolism. J Clin Invest 1976;57:1079-1082.
    • (1976) J Clin Invest , vol.57 , pp. 1079-1082
    • Wilcken, D.E.L.1    Wilcken, B.2
  • 45
    • 0030971062 scopus 로고    scopus 로고
    • Homocysteine and thrombotic disease
    • D'Angelo A, Selhub J. Homocysteine and thrombotic disease. Blood 1997;90:1-11.
    • (1997) Blood , vol.90 , pp. 1-11
    • D'Angelo, A.1    Selhub, J.2
  • 46
    • 0023696435 scopus 로고
    • Intermediate homocysteinemia: A thermolabile variant of methylenetetrahydrofolate reductase
    • Kang SS, Zhou J, Wong PWK, Kowalisyn J, Strokosch G. Intermediate homocysteinemia: A thermolabile variant of methylenetetrahydrofolate reductase. Am J Hum Genet 1988;43:414-421.
    • (1988) Am J Hum Genet , vol.43 , pp. 414-421
    • Kang, S.S.1    Zhou, J.2    Wong, P.W.K.3    Kowalisyn, J.4    Strokosch, G.5
  • 47
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
    • Frosst P, Blom HJ, Milos R, et al. A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase. Nat Genet 1995;10:111-113.
    • (1995) Nat Genet , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3
  • 49
    • 0031939674 scopus 로고    scopus 로고
    • The relationship between maternal and neonatal umbilical cord plasma homocysteine suggests a potential role for maternal homocysteine in fetal metabolism
    • Malinow MR, Rajkovic A, Druell PB, Hess DL, Upson BM. The relationship between maternal and neonatal umbilical cord plasma homocysteine suggests a potential role for maternal homocysteine in fetal metabolism. Obstet Gynecol 1998;178:228-233.
    • (1998) Obstet Gynecol , vol.178 , pp. 228-233
    • Malinow, M.R.1    Rajkovic, A.2    Druell, P.B.3    Hess, D.L.4    Upson, B.M.5
  • 51
    • 0033764843 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and pregnancy-review of our present understanding and therapeutic implications
    • Aubard Y, Darodes N, Cantaloube M. Hyperhomocysteinemia and pregnancy-review of our present understanding and therapeutic implications. Eur J Obstet Gynecol Repr Biol 2000;93:157-165.
    • (2000) Eur J Obstet Gynecol Repr Biol , vol.93 , pp. 157-165
    • Aubard, Y.1    Darodes, N.2    Cantaloube, M.3
  • 52
    • 0031828743 scopus 로고    scopus 로고
    • Effects of folic acid and vitamin B6 supplementation on women with hyperhomocysteinemia and a history of preeclampsia or fetal growth restriction
    • Leeda M, Riyazi N, De Vries JIP, Jacobs C, Van Geijn HP, Dekker GA. Effects of folic acid and vitamin B6 supplementation on women with hyperhomocysteinemia and a history of preeclampsia or fetal growth restriction. Am J Obstet Gynecol 1998;179:135-139.
    • (1998) Am J Obstet Gynecol , vol.179 , pp. 135-139
    • Leeda, M.1    Riyazi, N.2    De Vries, J.I.P.3    Jacobs, C.4    Van Geijn, H.P.5    Dekker, G.A.6
  • 54
    • 0032428626 scopus 로고    scopus 로고
    • Plasma homocysteine concentration is increased in preeclampsia and is associated with severe early onset preeclampsia
    • Powers RW, Evans RW, Majors AK, et al. Plasma homocysteine concentration is increased in preeclampsia and is associated with severe early onset preeclampsia. Am J Obstet Gynecol 1998;179:1605-1611.
    • (1998) Am J Obstet Gynecol , vol.179 , pp. 1605-1611
    • Powers, R.W.1    Evans, R.W.2    Majors, A.K.3
  • 55
    • 0027330937 scopus 로고
    • Hyperhomocysteinemia: A risk factor in women with unexpected recurrent early pregnancy loss
    • Wouters MG, Boers GH, Blom HJ, et al. Hyperhomocysteinemia: A risk factor in women with unexpected recurrent early pregnancy loss. Fertil Steril 1993;60:820-825.
    • (1993) Fertil Steril , vol.60 , pp. 820-825
    • Wouters, M.G.1    Boers, G.H.2    Blom, H.J.3
  • 56
    • 0032767244 scopus 로고    scopus 로고
    • Thrombophilic polymorphisms are common in women with fetal loss without apparent cause
    • Brenner B, Sarig G, Weiner Z, Younis J, Blumenfeld Z, Lanir N. Thrombophilic polymorphisms are common in women with fetal loss without apparent cause. Thromb Haemost 1999;82:6-9.
    • (1999) Thromb Haemost , vol.82 , pp. 6-9
    • Brenner, B.1    Sarig, G.2    Weiner, Z.3    Younis, J.4    Blumenfeld, Z.5    Lanir, N.6
  • 57
    • 0031883045 scopus 로고    scopus 로고
    • A woman with five consecutive fetal deaths: Case report and retrospective analysis of hyperhomocysteinemia prevalence in 100 consecutive women with recurrent miscarriages
    • Quere I, Bellet H, Hoffet M, Janbon C, Mares P, Gris JC. A woman with five consecutive fetal deaths: Case report and retrospective analysis of hyperhomocysteinemia prevalence in 100 consecutive women with recurrent miscarriages. Fertil Steril 1998;69:152-154.
    • (1998) Fertil Steril , vol.69 , pp. 152-154
    • Quere, I.1    Bellet, H.2    Hoffet, M.3    Janbon, C.4    Mares, P.5    Gris, J.C.6
  • 58
    • 0343471524 scopus 로고    scopus 로고
    • Genetic risk factor for unexplained recurrent early pregnancy loss
    • Nelen W, Steegers E, Eskes T, Blom H. Genetic risk factor for unexplained recurrent early pregnancy loss. Lancet 1997;350:861.
    • (1997) Lancet , vol.350 , pp. 861
    • Nelen, W.1    Steegers, E.2    Eskes, T.3    Blom, H.4
  • 60
    • 0033638057 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and recurrent early pregnancy loss: A meta-analysis
    • Nelen WL, Blom H, Steegers E, Den Heijer M, Eskes T. Hyperhomocysteinemia and recurrent early pregnancy loss: A meta-analysis. Fertil Steril 2000;74:1196-1199.
    • (2000) Fertil Steril , vol.74 , pp. 1196-1199
    • Nelen, W.L.1    Blom, H.2    Steegers, E.3    Den Heijer, M.4    Eskes, T.5
  • 61
    • 0032891393 scopus 로고    scopus 로고
    • The C677T MTHFR gene mutation is not predictive of risk for recurrent fetal loss
    • Holmes ZR, Regan L, Chilcott I, Cohen H. The C677T MTHFR gene mutation is not predictive of risk for recurrent fetal loss. Br J Haematol 1999;105:98-101.
    • (1999) Br J Haematol , vol.105 , pp. 98-101
    • Holmes, Z.R.1    Regan, L.2    Chilcott, I.3    Cohen, H.4
  • 62
    • 0029935556 scopus 로고    scopus 로고
    • Hyperhomocysteinemia: A risk factor for placental abruption or infarction
    • Goddijn-Wessel T, Wouters M, Molen E, et al. Hyperhomocysteinemia: A risk factor for placental abruption or infarction. Eur J Obstet Gynecol Repr Biol 1996;66:23-29.
    • (1996) Eur J Obstet Gynecol Repr Biol , vol.66 , pp. 23-29
    • Goddijn-Wessel, T.1    Wouters, M.2    Molen, E.3
  • 63
    • 0032543748 scopus 로고    scopus 로고
    • High risk of cerebral-vein thrombosis in carriers of a prothrombin-gene mutation and in users of oral contraceptives
    • Martinelli I, Sacchi E, Landi G, Taioli E, Duca F, Mannucci PM. High risk of cerebral-vein thrombosis in carriers of a prothrombin-gene mutation and in users of oral contraceptives. N Engl J Med 1998;338:1793-1797.
    • (1998) N Engl J Med , vol.338 , pp. 1793-1797
    • Martinelli, I.1    Sacchi, E.2    Landi, G.3    Taioli, E.4    Duca, F.5    Mannucci, P.M.6
  • 64
    • 0033515068 scopus 로고    scopus 로고
    • G20210A mutation in prothrombin gene and risk of myocardial infarction, stroke, and venous thrombosis in a large cohort of US men
    • Ridker PM, Hennekens CH, Miletich JP. G20210A mutation in prothrombin gene and risk of myocardial infarction, stroke, and venous thrombosis in a large cohort of US men. Circulation 1999;99:999-1004.
    • (1999) Circulation , vol.99 , pp. 999-1004
    • Ridker, P.M.1    Hennekens, C.H.2    Miletich, J.P.3
  • 65
    • 0031727435 scopus 로고    scopus 로고
    • The prothrombin G20210A allele is the most prevalent genetic risk factor for venous thromboembolism in the Spanish population
    • Souto JC, Coll I, Llobert D, et al. The prothrombin G20210A allele is the most prevalent genetic risk factor for venous thromboembolism in the Spanish population. Thromb Haemostas 1998;80:366-369.
    • (1998) Thromb Haemostas , vol.80 , pp. 366-369
    • Souto, J.C.1    Coll, I.2    Llobert, D.3
  • 66
    • 0032976317 scopus 로고    scopus 로고
    • Interaction between the G20210A mutation of the prothrombin gene and oral contraceptive use in deep vein thrombosis
    • Martinelli I, Taioli E, Bucciarelli P, Akhavan S, Mannucci M. Interaction between the G20210A mutation of the prothrombin gene and oral contraceptive use in deep vein thrombosis. Arterioscler Thromb Vasc Biol 1999;19:700-703.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 700-703
    • Martinelli, I.1    Taioli, E.2    Bucciarelli, P.3    Akhavan, S.4    Mannucci, M.5
  • 67
    • 0031726593 scopus 로고    scopus 로고
    • Genetic susceptibility to pregnancy-related venous thromboembolism: Roles of factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations
    • Grandone E, Margaglione M, Colaizzo D, et al. Genetic susceptibility to pregnancy-related venous thromboembolism: Roles of factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations. Am J Obstet Gynecol 1998;179:1324-1328.
    • (1998) Am J Obstet Gynecol , vol.179 , pp. 1324-1328
    • Grandone, E.1    Margaglione, M.2    Colaizzo, D.3
  • 68
    • 0033768987 scopus 로고    scopus 로고
    • High prevalence of the prothrombin gene mutation in women with intrauterine growth retardation, abruption placentae and second trimester loss
    • Kupferminc MJ, Peri H, Zwang E, Yaron Y, Wolman I, Eldor A. High prevalence of the prothrombin gene mutation in women with intrauterine growth retardation, abruption placentae and second trimester loss. Acta Obstet Gynecol Scand 2000;79:963-967.
    • (2000) Acta Obstet Gynecol Scand , vol.79 , pp. 963-967
    • Kupferminc, M.J.1    Peri, H.2    Zwang, E.3    Yaron, Y.4    Wolman, I.5    Eldor, A.6
  • 69
    • 0032972632 scopus 로고    scopus 로고
    • Prothrombotic genetic risk factors and the occurrence of gestational hypertension with or without proteinuria
    • Grandone E, Margaglione M, Colaizzo D, et al. Prothrombotic genetic risk factors and the occurrence of gestational hypertension with or without proteinuria. Thromb Haemost 1999;81:349-352.
    • (1999) Thromb Haemost , vol.81 , pp. 349-352
    • Grandone, E.1    Margaglione, M.2    Colaizzo, D.3
  • 70
    • 0032740843 scopus 로고    scopus 로고
    • Preeclampsia and genetic risk factors for thrombosis: A case-control study
    • De Groot CJM, Bloemenkamp KWM, Duvekot EJ, et al. Preeclampsia and genetic risk factors for thrombosis: A case-control study. Am J Obstet Gynaecol 1999;181:975-980.
    • (1999) Am J Obstet Gynaecol , vol.181 , pp. 975-980
    • De Groot, C.J.M.1    Bloemenkamp, K.W.M.2    Duvekot, E.J.3
  • 72
    • 0034919759 scopus 로고    scopus 로고
    • Thrombophilic gene mutations and recurrent spontaneous abortion: Prothrombin mutation increases the risk in the first trimester
    • Pihusch R, Buchholz T, Lohse P, et al. Thrombophilic gene mutations and recurrent spontaneous abortion: Prothrombin mutation increases the risk in the first trimester. Am J Reprod Immunol 2001;46:124-131.
    • (2001) Am J Reprod Immunol , vol.46 , pp. 124-131
    • Pihusch, R.1    Buchholz, T.2    Lohse, P.3
  • 73
    • 0035144589 scopus 로고    scopus 로고
    • G20210A prothrombin gene mutation: Prevalence in a recurrent miscarriage population
    • Pickering W, Marriott K, Regan L. G20210A prothrombin gene mutation: Prevalence in a recurrent miscarriage population. Clin Appl Thromb Hemost 2001;7:25-28.
    • (2001) Clin Appl Thromb Hemost , vol.7 , pp. 25-28
    • Pickering, W.1    Marriott, K.2    Regan, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.