RGS4 inhibits signaling by group I metabotropic glutamate receptors

Journal of Neuroscience

Volumn 18, Issue 3, 1998, Pages 905-913

  Saugstad, Julie A ^a   Marino, Michael J ^a   Folk, Julie A ^a   Hepler, John R ^a   Conn, P Jeffrey ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Rollins Research Building ^*  (United States)

Author keywords

G( ) proteins; Hippocampus; Metabotropic glutamate receptor; RGS proteins; RGS4; Synaptic regulation; Xenopus

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL TRISPHOSPHATE; METABOTROPIC RECEPTOR; PHOSPHOLIPASE C;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ENZYME ACTIVATION; ENZYME INHIBITION; NONHUMAN; OOCYTE; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; XENOPUS;

EID: 0031892347     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-03-00905.1998     Document Type: Article

References (6)

1. 2+ signal transduction. J Biol Chem 267:13361-13368.
2. AHP suppression by a metabotropic glutamate receptor agonist in rat dentate granule neurones. J Physiol (Lond) 496:139-144.
3. Akbar MT, Rattray M, Powell JF, Meldrum BS (1996) Altered expression of group I metabotropic glutamate receptors in the hippocampus of amygdala-kindled rats. Brain Res 43:105-116.
4. Akiyama K, Yamada,N Sato M (1987) Increase in ibotenate-stimulated phosphatidylinositol hydrolysis in slices of the amygdala/pyriform cortex and hippocampus of rat by amygdala kindling. Exp Neurol 98:499-508.
5. Aronica E, Frey U, Wagner M, Schroeder H, Krug M, Ruthrich H, Catania MV, Nicoletti F, Reymann KG (1991) Enhanced sensitivity of metabotropic glutamate receptors after induction of long-term potentiation in rat hippocampus. J Neurochem 57:376-383.
6. Balazs R, Miller S, Romano C, de Vries A, Chun Y, Cotman CW (1997) Metabotropic glutamate receptor mGIuRS in astrocytes: pharmacological properties and agonist regulation. J Neurochem 69:151-163.