N-end Rule Specificity within the Ubiquitin/Proteasome Pathway Is Not an Affinity Effect

Journal of Biological Chemistry

Volumn 276, Issue 42, 2001, Pages 39428-39437

  Baboshina, Olga V ^a   Crinelli, Rita ^b   Siepmann, Thomas J ^c   Haas, Arthur L ^d  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF URBINO   (Italy)

^c UNIVERSITY OF UTAH   (United States)

^d MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEGRADATION; HYDROPHOBICITY; PROTEINS; REACTION KINETICS; SUBSTRATES;

PROTEASOME PATHWAYS;

BIOCHEMISTRY;

CARRIER PROTEIN; CELL PROTEIN; DIPEPTIDE; LIGASE; LYSINE; LYSYLALANINE; PHENYLALANYLALANINE; POLYUBIQUITIN; PROTEASOME; UBIQUITIN; UBIQUITIN CONJUGATING ENZYME; UNCLASSIFIED DRUG; ALANINE; CYSTEINE PROTEINASE; LIGAND; MULTIENZYME COMPLEX; PEPTIDE; PHENYLALANINE;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; EQUILIBRIUM CONSTANT; HYDROPHOBICITY; KINETICS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN PURIFICATION; RABBIT; ANIMAL; BINDING COMPETITION; CATTLE; CHEMICAL MODEL; CHEMISTRY; DOSE RESPONSE; ENZYME SPECIFICITY; ENZYMOLOGY; GEL CHROMATOGRAPHY; LIVER; METABOLISM; PROTEIN TERTIARY STRUCTURE;

ANIMALIA; EUKARYOTA; MAMMALIA; ORYCTOLAGUS CUNICULUS;

ALANINE; ANIMALS; BINDING, COMPETITIVE; CATTLE; CHROMATOGRAPHY, GEL; CYSTEINE ENDOPEPTIDASES; DOSE-RESPONSE RELATIONSHIP, DRUG; KINETICS; LIGANDS; LIVER; MODELS, CHEMICAL; MULTIENZYME COMPLEXES; PEPTIDES; PHENYLALANINE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RABBITS; SUBSTRATE SPECIFICITY; UBIQUITIN;

EID: 0035914425     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M106967200     Document Type: Article

References (61)

1. Hershko, A., and Ciechanover, A. (1998) Annu. Rev. Biochem. 67, 425-479
2. Laney, J. D., and Hochstrasser, M. (1999) Cell 97, 427-430
3. Glickman, M. H., Rubin, D. M., Coux, O., Wefes, I., Pfeifer, G., Cjeka, Z., Baumeister, W., Fried, V. A., and Finley, D. (1998) Cell 94, 615-623
4. Chau, V., Tobias, J. W., Bachmair, A., Marriott, D., Ecker, D. J., Gonda, D. K., and Varshavsky, A. (1989) Science 243, 1576-1583
5. Baboshina, O. V., and Haas, A. L. (1996) J. Biol. Chem. 271, 2823-2831
6. Haas, A., Reback, P. M., Pratt, G., and Rechsteiner, M. (1990) J. Biol. Chem. 265, 21664-21669
7. Pickart, C. M. (2001) Annu. Rev. Biochem. 70, 503-533
8. Haas, A. L., Warms, J. V., Hershko, A., and Rose, I. A. (1982) J. Biol. Chem. 257, 2543-2548
9. Haas, A. L., and Rose, I. A. (1982) J. Biol. Chem. 257, 10329-10337
10. Haas, A. L., and Siepmann, T. J. (1997) FASEB J. 11, 1257-1268
11. Gray, W. M., del Pozo, J. C., Walker, L., Hobbie, L., Risseeuw, E., Banks, T., Crosby, W. L., Yang, M., Ma, H., and Estelle, M. (1999) Genes Dev. 13, 1678-1691
12. Bai, C., Sen, P., Hofmann, K., Ma, L., Goebl, M., Harper, J. W., and Elledge, S. J. (1996) Cell 86, 263-274
13. Lyapina, S. A., Correll, C. C., Kipreos, E. T., and Deshaies, R. J. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 7451-7456
14. Deshaies, R. J. (1999) Annu. Rev. Cell Dev. Biol. 15, 435-467
15. Banerjee, A., Deshaies, R. J., and Chau, V. (1995) J. Biol. Chem. 270, 26209-26215
16. Kaiser, P., Sia, R. A., Bardes, E. G., Lew, D. J., and Reed, S. I. (1998) Genes Dev. 12, 2587-2597
17. Kaiser, P., Flick, K., Wittenberg, C., and Reed, S. I. (2000) Cell 102, 303-314
18. Patton, E. E., Peyraud, C., Rouillon, A., Surdin-Kerjan, Y., Tyers, M., and Thomas, D. (2000) EMBO J. 19, 1613-1624
19. Jackson, P. K., Eldridge, A. G., Freed, E., Furstenthal, L., Hsu, J. Y., Kaiser, B. K., and Reimann, J. D. (10-0) Trends Cell Biol. 10, 429-439
20. Huibregtse, J. M., Scheffner, M., Beaudenon, S., and Howley, P. M. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 2563-2567
21. Kumar, S., Kao, W. H., and Howley, P. M. (1997) J. Biol. Chem. 272, 13548-13554
22. Lorick, K. L., Jensen, J. P., Fang, S., Ong, A. M., Hatakeyama, S., and Weissman, A. M. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 11364-11369
23. Aravind, L., and Koonin, E. V. (2000) Curr. Biol. 10, R132-R134
24. Bachmair, A., Finley, D., and Varshavsky, A. (1986) Science 234, 179-186
25. Hershko, A., Heller, H., Elias, S., and Ciechanover, A. (1983) J. Biol. Chem. 258, 8206-8214
26. Reiss, Y., and Hershko, A. (1990) J. Biol. Chem. 265, 3685-3690
27. Haas, A. L., Baboshina, O., Williams, B., and Schwartz, L. M. (1995) J. Biol. Chem. 270, 9407-9412
28. Kettelhut, I. C., Pepato, M. T., Migliorini, R. H., Medina, R., and Goldberg, A. L. (1994) Braz. J. Med. Biol. Res. 27, 981-993
29. Medina, R., Wing, S. S., Haas, A., and Goldberg, A. L. (1991) Biomed. Biochim. Acta 50, 347-356
30. Wing, S. S., Haas, A. L., and Goldberg, A. L. (1995) Biochem. J. 307, 639-645
31. Bachmair, A., and Varshavsky, A. (1989) Cell 56, 1019-1032
32. Hershko, A., Heller, H., Eytan, E., and Reiss, Y. (1986) J. Biol. Chem. 261, 11992-11999
33. Gonda, D. K., Bachmair, A., Wunning, I., Tobias, J. W., Lane, W. S., and Varshavsky, A. (1989) J. Biol. Chem. 264, 16700-16712
34. Bartel, B., W. unning, I., and Varshavsky, A. (1990) EMBO J. 9, 3179-3189
35. Kwon, Y. T., Reiss, Y., Fried, V. A., Hershko, A., Yoon, J. K., Gonda, D. K., Sangan, P., Copeland, N. G., Jenkins, N. A., and Varshavsky, A. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 7898-7903
36. Baker, R. T., and Varshavsky, A. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 1090-1094
37. Arfin, S. M., and Bradshaw, R. A. (1988) Biochemistry 27, 7979-7984
38. Haas, A. L., and Rose, I. A. (1981) Proc. Natl. Acad. Sci. U. S. A. 78, 6845-6848
39. Haas, A. L., Reback, P. B., and Chau, V. (1991) J. Biol. Chem. 266, 5104-5112
40. Haas, A. L., and Bright, P. M. (1988) J. Biol. Chem. 263, 13258-13267
41. Wing, S. S., Dumas, F., and Banville, D. (1992) J. Biol. Chem. 267, 6495-6501
42. Ho, S. N., Hunt, H. D., Horton, R. M., Pullen, J. K., and Pease, L. R. (1989) Genes (Amst.) 77, 51-59
43. Haas, A. L., Murphy, K. E., and Bright, P. M. (1985) J. Biol. Chem. 260, 4694-4703
44. Piez, K. A., Davie, E. W., Folk, J. E., and Gladner, J. A. (2000) J. Biol. Chem. 236, 2912-2916
45. Richards, F. M., and Vithayanthil, P. J. (2000) J. Biol. Chem. 234, 1459-1465
46. Wray, W., Boulikas, T., Wray, V. P., and Hancock, R. (1981) Anal. Biochem. 118, 197-203
47. Cook, R. J., and Wagner, C. (1995) Arch. Biochem. Biophys. 321, 336-344
48. Min, H., Shane, B., and Stokstad, E. L. (1988) Biochim. Biophys. Acta 967, 348-353
49. Cook, R. J., Lloyd, R. S., and Wagner, C. (1991) J. Biol. Chem. 266, 4965-4973
50. Reiss, Y., Kaim, D., and Hershko, A. (1988) J. Biol. Chem. 263, 2693-2698
51. Varshavsky, A. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 12142-12149
52. Heller, H., and Hershko, A. (1990) J. Biol. Chem. 265, 6532-6535
53. Byrd, C., Turner, G. C., and Varshavsky, A. (1998) EMBO J. 17, 269-277
54. Turner, G. C., Du, F., and Varshavsky, A. (2000) Nature 405, 579-583
55. Solomon, V., Baracos, V., Sarraf, P., and Goldberg, A. L. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 12602-12607
56. Solomon, V., Lecker, S. H., and Goldberg, A. L. (1998) J. Biol. Chem. 273, 25216-25222
57. Hondermarck, H., Sy, J., Bradshaw, R. A., and Arfin, S. M. (1992) Biochem. Biophys. Res. Commun. 189, 280-288
58. Obin, M., Mesco, E., Gong, X., Haas, A. L., Joseph, J., and Taylor, A. (1999) J. Biol. Chem. 274, 11789-11795
59. Gladding, R. L., Haas, A. L., Gronros, D. L., and Lawson, T. G. (1997) Biochem. Biophys. Res. Commun. 238, 119-125
60. Lawson, T. G., Gronros, D. L., Evans, P. E., Bastien, M. C., Michalewich, K. M., Clark, J. K., Edmonds, J. H., Graber, K. H., Werner, J. A., Lurvey, B. A., and Cate, J. M. (1999) J. Biol. Chem. 274, 9871-9880
61. Botbol, V., and Scornik, O. A. (1983) J. Biol. Chem. 258, 1942-1949