Hypoxia actively represses transcription by inducing negative cofactor 2 (Dr1/DrAP1) and blocking preinitiation complex assembly

Journal of Biological Chemistry

Volumn 278, Issue 8, 2003, Pages 5744-5749

  Denko, Nicholas ^a   Wernke Dollries, Kara ^b   Johnson, Amber Buescher ^c   Hammond, Ester ^a   Chiang, Cheng Ming ^d   Barton, Michelle Craig ^b,c  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENERGY CONSERVATION; GENES;

HYPOXIC STRESS;

BIOCHEMISTRY;

CELL EXTRACT; NEGATIVE COFACTOR 2; PREINITIATION COMPLEX; PROTEIN; PROTEIN DR1; PROTEIN DRAP1; RNA POLYMERASE II; UNCLASSIFIED DRUG; DRAP1 PROTEIN, HUMAN; REPRESSOR PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; GENE ACTIVATION; GENE REPRESSION; HUMAN; HUMAN CELL; HYPOXIA; HYPOXIC CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; STRESS; TRANSCRIPTION REGULATION; CELL CULTURE; CELL HYPOXIA; FIBROBLAST; GENETIC TRANSCRIPTION; GENETICS; LIVER CELL CARCINOMA; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; RNA TRANSLATION;

CARCINOMA, HEPATOCELLULAR; CELL HYPOXIA; CELLS, CULTURED; FIBROBLASTS; HUMANS; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); REPRESSOR PROTEINS; RNA POLYMERASE II; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0037458545     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212534200     Document Type: Article

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