Mapping the agonist binding site of the nicotinic acetylcholine receptor by cysteine scanning mutagenesis: Antagonist footprint and secondary structure prediction

Molecular Pharmacology

Volumn 61, Issue 2, 2002, Pages 463-472

  Sullivan, Deirdre ^a   Chiara, David C ^a   Cohen, Jonathan B ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; NICOTINIC AGENT; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; TUBOCURARINE CHLORIDE;

ALKYLATION; AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; DRUG RECEPTOR BINDING; NONHUMAN; PRIORITY JOURNAL; TORPEDO CALIFORNICA; XENOPUS LAEVIS;

AMINO ACID SUBSTITUTION; ANIMALS; BINDING, COMPETITIVE; CYSTEINE; ETHYL METHANESULFONATE; MESYLATES; MUTAGENESIS; NICOTINIC AGONISTS; OOCYTES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, NICOTINIC; TORPEDO; XENOPUS LAEVIS;

EID: 0036151496     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.61.2.463     Document Type: Article

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