Transgenic expression of the activating natural killer receptor Ly49H confers resistance to cytomegalovirus in genetically susceptible mice

Journal of Experimental Medicine

Volumn 197, Issue 4, 2003, Pages 515-526

  Lee, Seung Hwan ^a   Zafer, Ahmed ^b   De Repentigny, Yves ^b   Kothary, Rashmi ^b   Tremblay, Michel L ^c   Gros, Philippe ^c   Duplay, Pascale ^d   Webb, John R ^a   Vidal, Silvia M ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

^b OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d UNIVERSITÉ LAVAL   (Canada)

Author keywords

Animal model; Genetic complementation test; Immunogenetics; Natural immunity; Natural killer cells

Indexed keywords

CELL RECEPTOR; LYSINE;

ALLELISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CHROMOSOME 6; CONTROLLED STUDY; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; GENE CLUSTER; GENE LOCATION; GENE LOCUS; GENETIC ANALYSIS; GENETIC COMPLEMENTATION; GENETIC SUSCEPTIBILITY; IMMUNITY; IMMUNOGENETICS; INFECTION RESISTANCE; MOUSE; NATURAL KILLER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, LY; CHROMOSOMES, ARTIFICIAL, BACTERIAL; GENETIC COMPLEMENTATION TEST; GENETIC PREDISPOSITION TO DISEASE; HERPESVIRIDAE INFECTIONS; IMMUNITY, NATURAL; KILLER CELLS, NATURAL; LECTINS, C-TYPE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUROMEGALOVIRUS; TRANSGENES;

EID: 0037450814     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20021713     Document Type: Article

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