Induction of DAP12 phosphorylation, calcium mobilization, and cytokine secretion by Ly49H

Journal of Leukocyte Biology

Volumn 66, Issue 1, 1999, Pages 165-171

  Gosselin, Pierre ^b   Mason, Llewellyn H ^b   Willette Brown, Jami ^b   Ortaldo, John R ^b   McVicar, Daniel W ^b   Anderson, Stephen K ^a  

^a SAIC FREDERICK INC   (United States)

^b NONE

Author keywords

Natural killer cells; Signal transduction; Tumor necrosis factor

Indexed keywords

CALCIUM; TUMOR NECROSIS FACTOR ALPHA; TYROSINE;

ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; CELL ACTIVITY; CELL FUNCTION; COMPLEX FORMATION; CYTOKINE RELEASE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 1442268109     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.66.1.165     Document Type: Article

References (43)

1. Lanier, L. L. (1998) NK cell receptors. Annu. Rev. Immunol. 16, 359-393.
2. Yokoyama, W. M., Jacobs, L. B., Kanagawa, O., Shevach, E. M., Cohen, D. I., (1989) A murine T lymphocyte antigen belongs to a supergene family of type II integral membrane proteins. J. Immunol. 143, 1379-1386.
3. Wong, S., Freeman, J. D., Kelleher, C., Mager, D., Takei, F. (1991) Ly-49 multigene family. New members of a superfamily of type II membrane proteins with lectin-like domains. J. Immunol. 147, 1417-1423.
4. + IL-2-activated natural killer cells. Nature 358, 66-70.
5. Smith, H. R., Karlhofer, F. M., Yokoyama, W. M. (1994) Ly-49 multigene family expressed by IL-2-activated NK cells. J. Immunol. 153, 1068-1079.
6. Stoneman, E. R., Bennett, M., An, J., Chesnut, K. A., Wakeland, E. K., Scheerer, J. B., Siciliano, M. J., Kumar, V., Mathew, P. A. (1995) Cloning and characterization of 5E6(Ly-49C), a receptor molecule expressed on a subset of murine natural killer cells. J. Exp. Med. 182, 305-313.
7. Mason, L. H., Anderson, S. K., Yokoyama, W. M., Smith, H. R., Winkler-Pickett, R., Ortaldo, J. R. (1996) The Ly-49D receptor activates murine natural killer cells. J. Exp. Med. 184, 2119-2128.
8. McQueen, K. L., Freeman, J. D., Takei, F., Mager, D. L. (1998) Localization of five new Ly49 genes, including three closely related to Ly49c. Immunogenet. 48, 174-183.
9. Yu, Y. Y., George, T., Dorfman, J. R., Roland, J., Kumar, V., Bennett, M. (1996) The role of Ly49A and 5E6(Ly49C) molecules in hybrid resistance mediated by murine natural killer cells against normal T cell blasts. Immunity 4, 67-76.
10. Nakamura, M. C., Niemi, E. C., Fisher, M. J., Shultz, L. D., Seaman, W. E., Ryan, J. C. (1997) Mouse Ly-49A interrupts early signaling events in natural killer cell cytotoxicity and functionally associates with the SHP-I tyrosine phosphatase. J. Exp. Med. 185, 673-684.
11. Mason, L. H., Gosselin, P., Anderson, S. K., Fogler, W. E., Ortaldo, J. R., McVicar, D. W. (1997) Differential tyrosine phosphorylation of inhibitory versus activating Ly-49 receptor proteins and their recruitment of SHP-1 phosphatase. J. Immunol. 159, 4187-4196.
12. Mason, L. H., Willette-Brown, J., Anderson, S. K., Gosselin, P., Shores, E. W., Love, P. E., Ortaldo, J. R., McVicar, D. W. (1998) Characterization of an associated 16-kDa tyrosine phosphoprotein required for Ly-49D signal transduction. J. Immunol. 160, 4148-4152.
13. Olcese, L., Cambiaggi, A., Semenzato, G., Bottino, C., Moretta, A., Vivier, E. (1997) Human killer cell activatory receptors for MHC class I molecules are included in a multimeric complex expressed by natural killer cells. J. Immunol. 158, 5083-5086.
14. Campbell, K. S., Cella, M., Carretero, M., Lopez-Botet, M., Colonna, M. (1998) Signaling through human killer cell activating receptors triggers tyrosine phosphorylation of an associated protein complex. Eur. J. Immunol. 28, 599-609.
15. Lanier, L. L., Corliss, B. C., Wu, J., Leong, C., Phillips, J. H. (1998) Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells. Nature 391, 703-707.
16. Mason, L., Giardina, S. L., Hecht, T., Ortaldo, J., Mathieson, B. J. (1988) LGL-1: a non-polymorphic antigen expressed on a major population of mouse natural killer cells. J. Immunol. 140, 4403-4412.
17. Chan, P.-Y., Takei, F. (1986) Expression of a T cell receptor-like molecule on normal and malignant murine T cells detected by rat monoclonal antibodies to nonclonotypic determinants. J. Immunol. 136, 1346-1353.
18. Brennan, J., Mager, D., Jefferies, W., Takei, F. (1994) Expression of different members of the Ly-49 gene family defines distinct natural killer cell subsets and cell adhesion properties. J. Exp. Med. 180, 2287-2295.
19. McVicar, D. W., Taylor, L. S., Gosselin, P., Willette-Brown, J., Mikhael, A. I., Geahlen, R. L., Nakamura, M. C., Linnemeyer, P., Seaman, W. E., Anderson, S. K., Ortaldo, J. R., Mason, L. H. (1998) Dap-12 mediated signal transduction in NK cells: dominant role of the Syk protein lyrosine kinase. J. Biol. Chem. 273, 32934-32942.
20. Anegon, I., Cuturi, M. C., Trinchieri, G., Perussia, B. (1988) Interaction of Fc receptor (CD16) ligands induces transcription of interleukin 2 receptor (CD25) and lymphokine genes and expression of their products in human natural killer cells. J. Exp. Med. 167, 452-472.
21. Burshtyn, D. N., Scharenberg, A. M., Wagtmann, N., Rajagopalan, S., Berrada, K., Yi, T., Kinet, J. P., Long, E. O. (1996) Recruitment of tyrosine phosphatase HCP by the killer cell inhibitor receptor. Immunity 4, 77-85.
22. Fry, A. M., Lanier, L. L., Weiss, A. (1996) Phosphotyrosines in the killer cell inhibitory receptor motif of NKB1 are required for negative signaling and for association with protein tyrosine phosphatase 1C. J. Exp. Med. 184, 295-300.
23. Olcese, L., Lang, P., Vely, F., Cambiaggi, A., Marguet, D., Blery, M., Hippen, K. L., Biassoni, R., Moretta A., Moretta, L., Cambier, J. C., Vivier, E. (1996) Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases. J. Immunol. 156, 4531-4534.
24. Campbell, K. S., Dessing, M., Lopez-Botet, M., Cella, M., Colonna, M. (1996) Tyrosine phosphorylation of a human killer inhibitory receptor recruits protein tyrosine phosphatase 1C. J. Exp. Med. 184, 93-100.
25. Mason, L. H., Ortaldo, J. R., Young, H. A., Kumar, V., Bennett, M., Anderson, S. K., (1995) Cloning and functional characteristics of murine large granular lymphocyte-1: a member of the Ly-49 gene family (Ly-49G2). J. Exp. Med. 182, 293-303.
26. Smith, K. M., Wu, J., Bakker, A. B., Phillips, J. H., Lanier, L. L. (1998) Ly-49D and Ly-49H associate with mouse DAP12 and form activating receptors. J. Immunol. 161, 7-10.
27. Cantoni, C., Biassoni, R., Pende, D., Sivori, S., Accame, L., Pareti, L., Semenzato, G., Moretta, L., Moretta, A., Bottino, C. (1998) The activating form of CD94 receptor complex: CD94 covalently associates with the Kp39 protein that represents the product of the NKG2-C gene. Eur. J. Immunol. 28, 327-338.
28. Houchins, J. P., Yabe, T., McSherry, C., Bach, F. H. (1991) DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells. J. Exp. Med. 173, 1017-1020.
29. Brumbaugh, K. M., Perez-Villar, J. J., Dick, C. J., Schoon, R. A., Lopez-Botet, M., Leibson, P. J. (1996) Clonotypic differences in signaling from CD94 (kp43) on NK cells lead to divergent cellular responses. J. Immunol. 157, 2804-2812.
30. Leibson, P. J. (1997) Signal transduction during natural killer cell activation: inside the mind of a killer. Immunity 6, 655-661.
31. Lanier, L. L., Corliss, B., Wu, J., Phillips, J. H. (1998) Association of DAP12 with activating CD94/NKG2C NK cell receptors. Immunity 8, 693-701.
32. Perez-Villar, J. J., Melero, I., Rodriguez, A., Carretero, M., Aramburu, J., Sivori, S., Orengo, A. M., Moretta, A., Lopez-Botet, M. (1995) Functional ambivalence of the Kp43 (CD94) NK cell-associated surface antigen. J. Immunol. 154, 5779-5788.
33. Brumbaugh, K. M., Binstadt, B. A., Billadeau, D. D., Schoon, R. A., Dick, C. J., Ten, R. M., Leibson, P. J. (1997) Functional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicity. J. Exp. Med. 186, 1965-1974.
34. Kimura, T., Sakamoto, H., Appella, E., Siraganian, R. P. (1996) Conformational changes induced in the protein tyrosine kinase p72syk by tyrosine phosphorylation or by binding of phosphorylated immunoreceptor tyrosine-based activation motif peptides. Mol. Cell Biol. 16, 1471-1478.
35. Anderson, P., Caligiuri, M., Ritz, J., Schlossman, S. F. (1989) CD3-negative natural killer cells express zeta TCR as part of a novel molecular complex. Nature 341, 159-162.
36. Lanier, L. L., Yu, G., Phillips, J. H. (1989) Co-association of CD3 zeta with a receptor (CD16) for IgG Fc on human natural killer cells. Nature 342, 803-805.
37. Orloff, D. G., Ra, C. S., Frank, S. J., Klausner, R. D., Kinet, J. P. (1990) Family of disulphide-linked dimers containing the zeta and eta chains of the T-cell receptor and the gamma chain of Fc receptors. Nature 347, 189-191.
38. Kurosaki, T., Gander, I., Ravetch, J. V. (1991) A subunit common to an IgG Fc receptor and the T-cell receptor mediates assembly through different interactions. Proc. Natl. Acad. Sci. USA 88, 3837-3841.
39. -/- mutant mice and identification of a novel T cell population in the intestine. EMBO J. 12, 4863-4875.
40. Takai, T., Li, M., Sylvestre, D., Clynes, R., Ravetch, J. V. (1994) FcR gamma chain deletion results in pleiotrophic effector cell defects. Cell 76, 519-529.
41. Bonnema, J. D., Karnitz, L. M., Schoon, R. A., Abraham, R. T., Leibson, P. J. (1994) Fc receptor stimulation of phosphatidylinositol 3-kinase in natural killer cells is associated with protein kinase C-independent granule release and cell-mediated cytotoxicity. J. Exp. Med. 180, 1427-1435.
42. Lanier, L. L., Ruitenberg, J., Phillips, J. H. (1989) Functional and biochemical analysis of CD16 antigen on natural killer cells and granulocytes. J. Immunol. 141, 3478-3485.
43. Ortaldo, J. R., Mason, A. T., O'Shea, J. J. (1995) Receptor-induced death in human natural killer cells: involvement of CD16. J. Exp. Med. 181, 339-334.