Properties of the human muscle nicotinic receptor, and of the slow-channel myasthenic syndrome mutant εL221F, inferred from maximum likelihood fits

Journal of Physiology

Volumn 547, Issue 3, 2003, Pages 729-760

  Hatton, C J ^a   Shelley, C ^a   Brydson, M ^b   Beeson, D ^b   Colquhoun, D ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; LIGAND; NICOTINIC RECEPTOR; RECOMBINANT RECEPTOR;

BINDING AFFINITY; BINDING SITE; CELL FUNCTION; CHANNEL GATING; COMPUTER PROGRAM; COMPUTER SIMULATION; CONCENTRATION (PARAMETERS); CONSTANTS AND COEFFICIENTS; CONTROLLED STUDY; DISSOCIATION; EATON LAMBERT SYNDROME; GENE MUTATION; HUMAN; HUMAN CELL; MATHEMATICAL COMPUTING; MAXIMUM LIKELIHOOD METHOD; MINIATURE ENDPLATE POTENTIAL; MUSCLE CELL; PRIORITY JOURNAL; REVIEW; TIME; WILD TYPE;

ACETYLCHOLINE; AMINO ACID SEQUENCE; BINDING SITES; CELL LINE; HUMANS; ION CHANNEL GATING; KIDNEY; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUSCLE, SKELETAL; MYASTHENIC SYNDROMES, CONGENITAL; PATCH-CLAMP TECHNIQUES; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, NICOTINIC; RECOMBINANT PROTEINS; SYNAPTIC TRANSMISSION;

EID: 0037444682     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2002.034173     Document Type: Review

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