Contributions of Torpedo Nicotinic Acetylcholine Receptor γTrp-55 and δTrp-57 to Agonist and Competitive Antagonist Function

Journal of Biological Chemistry

Volumn 276, Issue 4, 2001, Pages 2417-2426

  Xie, Yu ^a   Cohen, Jonathan B ^b  

^a MILLENNIUM PHARMACEUTICALS INC   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOASSAY; CHEMICAL ACTIVATION; ELECTROPHYSIOLOGY; MUTAGENESIS;

MUTATIONAL ANALYSIS;

BIOCHEMISTRY;

ACETYLCHOLINE; LEUCINE; NICOTINIC AGENT; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; TRITIUM; TRYPTOPHAN; TUBOCURARINE CHLORIDE; PROTEIN SUBUNIT; RECOMBINANT PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING ASSAY; BINDING SITE; CHANNEL GATING; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; DRUG RECEPTOR BINDING; ELECTROPHYSIOLOGY; MUTATIONAL ANALYSIS; NONHUMAN; OOCYTE; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; TORPEDO; XENOPUS; ANIMAL; DOSE RESPONSE; DRUG EFFECT; GENETICS; METABOLISM; MUTATION;

ANIMALIA; TORPEDO;

ACETYLCHOLINE; ANIMALS; BINDING SITES; DOSE-RESPONSE RELATIONSHIP, DRUG; ION CHANNEL GATING; MUTATION; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; PHOTOAFFINITY LABELS; PROTEIN SUBUNITS; RECEPTORS, NICOTINIC; RECOMBINANT PROTEINS; TORPEDO; TRYPTOPHAN; TUBOCURARINE;

EID: 0035951772     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009085200     Document Type: Article

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