Regulation of leukotriene-dependent induction of cyclooxygenase-2 and Bcl-2

Biochemical and Biophysical Research Communications

Volumn 302, Issue 2, 2003, Pages 330-335

  Wikström, Katarina ^a   Öhd, John F ^a   Sjölander, Anita ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Bcl 2; Cyclooxygenase 2; Intestinal epithelial cell survival; Leukotriene; MAPK; Prostaglandin

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 6 ISOPROPOXY 9 OXO 2 XANTHENECARBOXYLIC ACID; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; GUANINE NUCLEOTIDE BINDING PROTEIN; LEUKOTRIENE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PERTUSSIS TOXIN; PROTEIN BCL 2;

ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NEGATIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; UPREGULATION;

EID: 0037428284     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)00187-6     Document Type: Article

References (28)

1. Shao J., Sheng H., Inoue H., Morrow J.D., DuBois R.N. Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells. J. Biol. Chem. 275:2000;33951-33956.
2. Eberhart C.E., Coffey R.J., Radhika A., Giardiello F.M., Ferrenbach S., DuBois R.N. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology. 107:1994;1183-1188.
3. Wolff H., Saukkonen K., Anttila S., Karjalainen A., Vainio H., Ristimaki A. Expression of cyclooxygenase-2 in human lung carcinoma. Cancer Res. 58:1998;4997-5001.
4. 2 on proliferation and apoptosis of epithelial ovarian cancer cells J. Soc. Gynecol. Investig. 2002;168-173.
5. 2 increases growth and motility of colorectal carcinoma cells J. Biol. Chem. 276:2001;18075-18081.
6. Samuelsson B., Dahlen S.E., Lindgren J.A., Rouzer C.A., Serhan C.N. Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. Science. 237:1987;1171-1176.
7. 1 receptor Nature. 399:1999;789-793.
8. Heise C.E., O'Dowd B.F., Figueroa D.J., Sawyer N., Nguyen T., Im D.S., Stocco R., Bellefeuille J.N., Abramovitz M., Cheng R., Williams D.L., Zeng Z., Liu Q., Ma L., Clements M.K., Coulombe N., Liu Y., Austin C.P., George S.R., O'Neill G.P., Metters K.M., Lynch K.R., Evans J.F. Characterization of the human cysteinyl leukotriene 2 receptor. J. Biol. Chem. 275:2000;30531-30536.
9. i3 -subunit in human epithelial cells Biochem. Biophys. Res. Commun. 226:1996;413-419.
10. Öhd J.F., Wikström K., Sjölander A. Leukotrienes induce cell-survival signaling in intestinal epithelial cells. Gastroenterology. 119:2000;1007-1018.
11. 1, COX-2 and other cell survival factors in colorectal adenocarcinomas Gastroenterology. 124:2003;57-70.
12. Stenson W.F. Role of eicosanoids as mediators of inflammation in inflammatory bowel disease. Scand. J. Gastroenterol. Suppl. 172:1990;13-18.
13. Ekbom A., Helmick C., Zack M., Adami H.O. Ulcerative colitis and colorectal cancer. A population-based study. N. Engl. J. Med. 323:1990;1228-1233.
14. Garrington T.P., Johnson G.L. Organization and regulation of mitogen-activated protein kinase signaling pathways. Curr. Opin. Cell Biol. 11:1999;211-218.
15. Sheng H., Williams C.S., Shao J., Liang P., DuBois R.N., Beauchamp R.D. Induction of cyclooxygenase-2 by activated Ha-ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway. J. Biol. Chem. 273:1998;22120-22127.
16. Guan Z., Buckman S.Y., Pentland A.P., Templeton D.J., Morrison A.R. Induction of cyclooxygenase-2 by the activated MEKK1. → SEK1/MKK4 → p38 mitogen-activated protein kinase pathway J. Biol. Chem. 273:1998;12901-12908.
17. Rikitake Y., Hirata K., Kawashima S., Takeuchi S., Shimokawa Y., Kojima Y., Inoue N., Yokoyama M. Signaling mechanism underlying COX-2 induction by lysophosphatidylcholine. Biochem. Biophys. Res. Commun. 281:2001;1291-1297.
18. 4 activates MAPK through a Ras-independent but PKCε-dependent pathway in intestinal epithelial cells J. Cell Sci. 115:2002;1883-1893.
19. Jones M.K., Sasaki E., Halter F., Pai R., Nakamura T., Arakawa T., Kuroki T., Tarnawski A.S. HGF triggers activation of the COX-2 gene in rat gastric epithelial cells: action mediated through the ERK2 signaling pathway. FASEB J. 13:1999;2186-2194.
20. Adams J.M., Cory S. Life-or-death decisions by the Bcl-2 protein family. Trends Biochem. Sci. 26:2001;61-66.
21. 2 in human colon cancer cells Cancer Res. 58:1998;362-366.
22. Futaki N., Takahashi S., Yokoyama M., Arai I., Higuchi S., Otomo S. NS-398, a new anti-inflammatory agent selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro. Prostaglandins. 47:1994;55-59.
23. Parker J., Kaplon M.K., Alvarez C.J., Krishnaswamy G. Prostaglandin H synthase expression is variable in human colorectal adenocarcinoma cell lines. Exp. Cell Res. 236:1997;321-329.
24. 4 affects localisation of vinculin in intestinal epithelial cells via distinct tyrosine kinase and protein kinase C controlled events J. Cell Sci. 114:2001;1925-1934.
25. L, and Mcl-1 and promotes survival of human pancreatic cancer cells J. Cell. Biochem. 79:2000;355-369.
26. Kutchera W., Jones D.A., Matsunami N., Groden J., McIntyre T.M., Zimmerman G., White R.L., Prescott S.M. Prostaglandin H synthase 2 is expressed abnormally in human colon cancer: evidence for a transcriptional effect. Proc. Natl. Acad. Sci. USA. 93:1996;4816-4820.
27. Elder D.J., Halton D.E., Playle L.C., Paraskeva C. The MEK/ERK pathway mediates COX-2-selective NSAID-induced apoptosis and induced COX-2 protein expression in colorectal carcinoma cells. Int. J. Cancer. 99:2002;323-327.
28. Husain S.S., Szabo I.L., Pai R., Soreghan B., Jones M.K., Tarnawski A.S. MAPK (ERK2) kinase - a key target for NSAIDs-induced inhibition of gastric cancer cell proliferation and growth. Life Sci. 69:2001;3045-3054.