MAPK (ERK2) kinase - A key target for NSAIDs-induced inhibition of gastric cancer cell proliferation and growth

Life Sciences

Volumn 69, Issue 25-26, 2001, Pages 3045-3054

  Husain, S S ^a,b   Szabo, I L ^b   Pai, R ^b   Soreghan, B ^b   Jones, M K ^b   Tarnawski, A S ^a,b  

^a VA LONG BEACH HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apoptosis; Cell proliferation; ERK2; Gastric cancer; MAPK

Indexed keywords

INDOMETACIN; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MYELIN BASIC PROTEIN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PHOSPHATE; PHOSPHOTRANSFERASE; PROSTAGLANDIN SYNTHASE INHIBITOR; THYMIDINE; TRITIUM;

ADENOCARCINOMA; APOPTOSIS; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CELL CULTURE; CELL LINE; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; ISOTOPE LABELING; NICK END LABELING; PHOSPHORYLATION; SIGNAL TRANSDUCTION; STOMACH CANCER; STOMACH EPITHELIUM;

ADENOCARCINOMA; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; CELL DIVISION; CYCLOOXYGENASE INHIBITORS; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; IN SITU NICK-END LABELING; INDOMETHACIN; MITOGEN-ACTIVATED PROTEIN KINASE 1; NITROBENZENES; RAS PROTEINS; STOMACH NEOPLASMS; SULFONAMIDES; THYMIDINE; TUMOR CELLS, CULTURED;

EID: 0035834306     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(01)01411-4     Document Type: Conference Paper

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