Effects of prostaglandin E2 on proliferation and apoptosis of epithelial ovarian cancer cells

Journal of the Society for Gynecologic Investigation

Volumn 9, Issue 3, 2002, Pages 168-173

  Munkarah, A R ^a   Morris, R ^a   Baumann, P ^a   Deppe, G ^a   Malone, J ^a   Diamond, M P ^a   Saed, G M ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Ovarian cancer; Prostaglandins

Indexed keywords

CYCLOOXYGENASE 2; PROSTAGLANDIN E2; PROTEIN BAX; PROTEIN BCL 2; RNA;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CELL CYCLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; EPITHELIUM; GENE AMPLIFICATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; OVARY CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REDUCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

APOPTOSIS; BASE SEQUENCE; BCL-2-ASSOCIATED X PROTEIN; CELL DIVISION; CYCLOOXYGENASE 2; DINOPROSTONE; DNA PRIMERS; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IN SITU NICK-END LABELING; ISOENZYMES; KINETICS; MEMBRANE PROTEINS; OVARIAN NEOPLASMS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0036247943     PISSN: 10715576     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1071-5576(02)00141-7     Document Type: Article

References (34)

1. Cyclooxygenase-2 overexpression enhances lymphatic invasion and metastasis in human gastric carcinoma
2. Expression of COX-2 in human lung carcinoma
3. COX-2 is expressed in human pulmonary, colonic, and mammary tumors
4. Cytoplasmic induction and over-expression of COX-2 in human prostate cancer: Implication for prevention and treatment
5. Enhanced expression of COX-2 in human skin epidermal cancer cells: Evidence for growth suppression by inhibiting COX-2 expression
6. 2 synthesis are upregulated in carcinomas of the cervix: A possible autocrine/paracrine regulation of neoplastic cell function via EP2/EP4 receptors
7. Expression of COX-2 in human transitional cell carcinoma of the urinary bladder
8. COX-2 is overexpressed in human cervical cancer
9. Increased expression of COX-2 in human pancreatic neoplasms and potential for chemoprevention by COX inhibitors
10. Eicosanoids and the gastrointestinal tract
11. Towards a better aspirin
12. Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors
13. TS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue
14. The role of cytokines in the production of prostacyclin and thromboxane in human mononuclear cells
15. Prostaglandin E production and metabolism in human breast cancer cells and breast fibroblasts. Regulation by inflammatory mediators
16. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
17. Cyclooxygenase-1 and cyclooxygenase-2 gene expression in human colorectal adenocarcinomas and in azoxymethane induced colonic tumours in rats
18. Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer
19. Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: Growth inhibition by nonsteroidal anti-inflammatory drugs
20. Expression of cyclooxygenase-2 in human gastric carcinoma
21. Expression of cyclooxgenase-1 and -2 in human colorectal cancer
22. Effect of aspirin and non-steroidal anti-inflammatory drugs reduce the incidence of large-bowel cancer
23. Aspirin and the potential role of prostaglandins in colon cancer
24. Aspirin use and risk of fatal cancer
25. Reduced risk of large-bowel adenomas among aspirin users
26. Aspirin and the risk of colorectal cancer in women
27. Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2
28. Prostaglandin endoperoxide synthase in rat ovarian follicles: Content, cellular distribution, and evidence for hormonal induction preceding ovulation
29. 2 by human granulosa cells from polycystic ovaries
30. Alteration of type I and III collagen expression in human peritoneal mesothelial cells in response to hypoxia and transforming growth β1
31. Mycosis fungoides exhibits as Th1-type cell-mediated cytokine profile whereas Sezary syndrome expresses a Th2-type profile
32. 2 in human prostatic carcinoma cells
33. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
34. Sulindac sulfide, an aspirin-like compound, inhibits proliferation, causes cell cycle quiescence, and induces apoptosis in HT-29 colon adenocarcinoma cells