Engineering cell adhesive surfaces that direct integrin α5β1 binding using a recombinant fragment of fibronectin

Biomaterials

Volumn 24, Issue 10, 2003, Pages 1759-1770

  Cutler, Sarah M ^a   García, Andrés J ^b  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Biomimetic; Cell adhesion; Fibronectin; Integrins; RGD

Indexed keywords

ADHESIVES; BIOMIMETIC MATERIALS; CONCENTRATION (PROCESS); PROTEINS;

RECOMBINANT FRAGMENTS;

CELLS;

ALBUMIN; ALPHA5 INTEGRIN; ANTIBODY; BETA1 INTEGRIN; CYSTEINE; FIBRONECTIN; LYSINE; RECOMBINANT PROTEIN; TALIN; VINCULIN;

ANIMAL CELL; ARTICLE; BINDING SITE; BIOMIMETICS; CELL ADHESION; CELL ASSAY; CELL SPREADING; CELL SURFACE; CONTROLLED STUDY; EMBRYO; ENZYME LINKED IMMUNOSORBENT ASSAY; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN IMMOBILIZATION;

EID: 0037404371     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(02)00570-7     Document Type: Article

References (65)

1. Hynes R.O. Integrins. versatility, modulation, and signaling in cell adhesion Cell. 69:1992;11-25.
2. Damsky C.H. Extracellular matrix-integrin interactions in osteoblast function and tissue remodeling. Bone. 25:1999;95-96.
3. De Arcangelis A., Georges-Labouesse E. Integrin and ECM functions. roles in vertebrate development Trends Genet. 16:2000;389-395.
4. George E.L., Georges-Labouesse E.N., Patel-King R.S., Rayburn H., Hynes R.O. Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. Development. 119:1993;1079-1091.
5. Stephens L.E., Sutherland A.E., Klimanskaya I.V., Andrieux A., Meneses J., Pedersen R.A., Damsky C.H. Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality. Genes Dev. 9:1995;1883-1895.
6. Furuta Y., Ilic D., Kanazawa S., Takeda N., Yamamoto T., Aizawa S. Mesodermal defect in late phase of gastrulation by a targeted mutation of focal adhesion kinase, FAK. Oncogene. 11:1995;1989-1995.
7. Xu W., Baribault H., Adamson E.D. Vinculin knockout results in heart and brain defects during embryonic development. Development. 125:1998;327-337.
8. Ziats N.P., Miller K.M., Anderson J.M. In vitro and in vivo interactions of cells with biomaterials. Biomaterials. 9:1988;5-13.
9. Koller M.R., Papoutsakis E.T. Cell adhesion in animal cell culture. physiological and fluid-mechanical implications Bioprocess Technol. 20:1995;61-110.
10. Langer R., Vacanti J.P. Tissue engineering. Science. 260:1993;920-926.
11. Menko A.S., Boettiger D. Occupation of the extracellular matrix receptor integrin is a control point for myogenic differentiation. Cell. 51:1987;51-57.
12. Werb Z., Tremble P.M., Behrendtsen O., Crowley E., Damsky C.H. Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression. J Cell Biol. 109:1989;877-889.
13. Streuli C.H., Schmidhauser C., Bailey N., Yurchenco P., Skubitz A.P., Roskelley C., Bissell M.J. Laminin mediates tissue-specific gene expression in mammary epithelia. J Cell Biol. 129:1995;591-603.
14. Zhu X., Ohtsubo M., Bohmer R.M., Roberts J.M., Assoian R.K. Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein. J Cell Biol. 133:1996;391-403.
15. García A.J., Vega M.D., Boettiger D. Modulation of cell proliferation and differentiation through substrate-dependent changes in fibronectin conformation. Mol Biol Cell. 10:1999;785-798.
16. Jockusch B.M., Bubeck P., Giehl K., Kroemker M., Moschner J., Rothkegel M., Rudiger M., Schluter K., Stanke G., Winkler J. The molecular architecture of focal adhesions. Annu Rev Cell Dev Biol. 11:1995;379-416.
17. Burridge K., Chrzanowska-Wodnicka M. Focal adhesions, contractility, and signaling. Annu Rev Cell Dev Biol. 12:1996;463-518.
18. Almeida E.A., Ilic D., Han Q., Hauck C.R., Jin F., Kawakatsu H., Schlaepfer D.D., Damsky C.H. Matrix survival signaling. from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase J Cell Biol. 149:2000;741-754.
19. Sieg D.J., Hauck C.R., Ilic D., Klingbeil C.K., Schaefer E., Damsky C.H., Schlaepfer D.D. FAK integrates growth-factor and integrin signals to promote cell migration. Nat Cell Biol. 2:2000;249-256.
20. Sastry S.K., Lakonishok M., Wu S., Truong T.Q., Huttenlocher A., Turner C.E., Horwitz A.F. Quantitative changes in integrin and focal adhesion signaling regulate myoblast cell cycle withdrawal. J Cell Biol. 144:1999;1295-1309.
21. Gallant N.D., Capadona J.R., Frazier A.B., Collard D.M., García A.J. Micropatterned surfaces for analyzing cell adhesion strengthening. Langmuir. 18:2002;5579-5584.
22. Ruoslahti E., Pierschbacher M.D. Arg-Gly-Asp. a versatile cell recognition signal Cell. 44:1986;517-517.
23. van der Flier A., Sonnenberg A. Function and interactions of integrins. Cell Tissue Res. 305:2001;285-298.
24. Obara M., Kang M.S., Yamada K.M. Site-directed mutagenesis of the cell-binding domain of human fibronectin. separable, synergistic sites mediate adhesive function Cell. 53(4):1988;649-657.
25. Bowditch R.D., Hariharan M., Tominna E.F., Smith J.W., Yamada K.M., Getzoff E.D., Ginsberg M.H. Identification of a novel integrin binding site in fibronectin. Differential utilization by beta 3 integrins. J Biol Chem. 269:1994;10856-10863.
26. Moursi A.M., Globus R.K., Damsky C.H. Interactions between integrin receptors and fibronectin are required for calvarial osteoblast differentiation in vitro. J Cell Sci. 110:1997;2187-2196.
27. Roovers K., Davey G., Zhu X., Bottazzi M.E., Assoian R.K. Alpha5beta1 integrin controls cyclin D1 expression by sustaining mitogen-activated protein kinase activity in growth factor-treated cells. Mol Biol Cell. 10:1999;3197-3204.
28. Wu C., Bauer J.S., Juliano R.L., McDonald J.A. The alpha 5 beta 1 integrin fibronectin receptor, but not the alpha 5 cytoplasmic domain, functions in an early and essential step in fibronectin matrix assembly. J Biol Chem. 268:1993;21883-21888.
29. Aota S., Nomizu M., Yamada K.M. The short amino acid sequence Pro-His-Ser-Arg-Asn in human fibronectin enhances cell-adhesive function. J Biol Chem. 269:1994;24756-24761.
30. Redick S.D., Settles D.L., Briscoe G., Erickson H.P. Defining fibronectin's cell adhesion synergy site by site-directed mutagenesis. J Cell Biol. 149:2000;521-527.
31. García A.J., Schwarzbauer J.E., Boettiger D. Distinct activation states of alpha5beta1 integrin show differential binding to RGD and synergy domains of fibronectin. Biochemistry. 41:2002;9063-9069.
32. Grant R.P., Spitzfaden C., Altroff H., Campbell I.D., Mardon H.J. Structural requirements for biological activity of the ninth and tenth FIII domains of human fibronectin. J Biol Chem. 272:1997;6159-6166.
33. Hubbell J.A. Bioactive biomaterials. Curr Opin Biotechnol. 10:1999;123-129.
34. Shakesheff K., Cannizzaro S., Langer R. Creating biomimetic micro-environments with synthetic polymer-peptide hybrid molecules. J Biomater Sci Polym Ed. 9:1998;507-518.
35. Matsuda T., Kondo A., Makino K., Akutsu T. Development of a novel artificial matrix with cell adhesion peptides for cell culture and artificial and hybrid organs. ASAIO Trans. 35:1989;677-679.
36. Massia S.P., Hubbell J.A. Covalent surface immobilization of Arg-Gly-Asp- and Tyr-Ile-Gly-Ser-Arg- containing peptides to obtain well-defined cell-adhesive substrates. Anal Biochem. 187:1990;292-301.
37. Drumheller P.D., Hubbell J.A. Polymer networks with grafted cell adhesion peptides for highly biospecific cell adhesive substrates. Anal Biochem. 222:1994;380-388.
38. Dee K.C., Rueger D.C., Andersen T.T., Bizios R. Conditions which promote mineralization at the bone-implant interface. a model in vitro study Biomaterials. 17:1996;209-215.
39. Bearinger J.P., Castner D.G., Healy K.E. Biomolecular modification of p(AAm-co-EG/AA) IPNs supports osteoblast adhesion and phenotypic expression. J Biomater Sci Polym Ed. 9:1998;629-652.
40. Hern D.L., Hubbell J.A. Incorporation of adhesion peptides into nonadhesive hydrogels useful for tissue resurfacing. J Biomed Mater Res. 39:1998;266-276.
41. Neff J.A., Caldwell K.D., Tresco P.A. A novel method for surface modification to promote cell attachment to hydrophobic substrates. J Biomed Mater Res. 40:1998;511-519.
42. Rezania A., Healy K.E. Biomimetic peptide surfaces that regulate adhesion, spreading, cytoskeletal organization, and mineralization of the matrix deposited by osteoblast-like cells. Biotechnol Prog. 15:1999;19-32.
43. Mann B.K., Gobin A.S., Tsai A.T., Schmedlen R.H., West J.L. Smooth muscle cell growth in photopolymerized hydrogels with cell adhesive and proteolytically degradable domains. synthetic ECM analogs for tissue engineering Biomaterials. 22:2001;3045-3051.
44. Alsberg E., Anderson K.W., Albeiruti A., Franceschi R.T., Mooney D.J. Cell-interactive alginate hydrogels for bone tissue engineering. J Dent Res. 80:2001;2025-2029.
45. Sofia S., McCarthy M.B., Gronowicz G., Kaplan D.L. Functionalized silk-based biomaterials for bone formation. J Biomed Mater Res. 54:2001;139-148.
46. Massia S.P., Stark J. Immobilized RGD peptides on surface-grafted dextran promote biospecific cell attachment. J Biomed Mater Res. 56:2001;390-399.
47. Yang X.B., Roach H.I., Clarke N.M., Howdle S.M., Quirk R., Shakesheff K.M., Oreffo R.O. Human osteoprogenitor growth and differentiation on synthetic biodegradable structures after surface modification. Bone. 29:2001;523-531.
48. Pierschbacher M.D., Hayman E.G., Ruoslahti E. Synthetic peptide with cell attachment activity of fibronectin. Proc Natl Acad Sci USA. 80:1983;1224-1227.
49. Akiyama S.K., Aota S., Yamada K.M. Function and receptor specificity of a minimal 20 kilodalton cell adhesive fragment of fibronectin. Cell Adhes Commun. 3:1995;13-25.
50. Aukhil I., Joshi P., Yan Y., Erickson H.P. Cell- and heparin-binding domains of the hexabrachion arm identified by tenascin expression proteins. J Biol Chem. 268:1993;2542-2553.
51. Stephansson S.N., Byers B.A., García A.J. Enhanced expression of the osteoblastic phenotype on substrates that modulate fibronectin conformation and integrin receptor binding. Biomaterials. 23:2002;2527-2534.
52. Schoen R.C., Bentley K.L., Klebe R.J. Monoclonal antibody against human fibronectin inhibits cell attachment. Hybridoma. 1:1982;99-108.
53. Keselowsky BG, Collard DM, García AJ. Surface chemistry modulates fibronectin conformation and directs integrin binding and specificity to control cell adhesion. J Biomed Mater Res, in press.
54. Minchiotti L., Galliano M., Kragh-Hansen U., Watkins S., Madison J., Putnam F.W. A genetic variant of albumin (albumin Asola; Tyr140→Cys) with no free -SH group but with an additional disulfide bridge. Eur J Biochem. 228:1995;155-159.
55. Hermanson G.T. Bioconjugate techniques. 1996;Academic Press, San Diego, CA.
56. Biran R., Webb K., Noble M.D., Tresco P.A. Surfactant-immobilized fibronectin enhances bioactivity and regulates sensory neurite outgrowth. J Biomed Mater Res. 55:2001;1-12.
57. Reyes CD, García AJ. Engineering integrin-specific surfaces with a triple-helical collagen-mimetic peptide. J Biomed Mater Res, in press.
58. Roberts C., Chen C.S., Mrksich M., Martichonok V., Ingber D.E., Whitesides G.M. Using mixed self-assembled monolayers presenting RGD and (EG)3OH groups to characterize long-term attachment of bovine capillary endothelial cells to surfaces. J Am Chem Soc. 120:1998;6548-6555.
59. Kao W.J., Lee D., Schense J.C., Hubbell J.A. Fibronectin modulates macrophage adhesion and FBGC formation. the role of RGD, PHSRN, and PRRARV domains J Biomed Mater Res. 55:2001;79-88.
60. Dee K.C., Andersen T.T., Bizios R. Design and function of novel osteoblast-adhesive peptides for chemical modification of biomaterials. J Biomed Mater Res. 40:1998;371-377.
61. Giancotti F.G., Ruoslahti E. Integrin signaling. Science. 285:1999;1028-1032.
62. Grinnell F., Feld M., Minter D. Fibroblast adhesion to fibrinogen and fibrin substrata. requirement for cold-insoluble globulin (plasma fibronectin) Cell. 19:1980;517-525.
63. Lahav J., Hynes R.O. Involvement of fibronectin, Von Willebrand factor, and fibrinogen in platelet interaction with solid substrata. J Supramol Struct Cell Biochem. 17:1981;299-311.
64. Stanton H., Ung L., Fosang A.J. The 45. kDa collagen-binding fragment of fibronectin induces matrix metalloproteinase-13 synthesis by chondrocytes and aggrecan degradation by aggrecanases Biochem J. 364:2002;181-190.
65. Yasuda T., Poole A.R. A fibronectin fragment induces type II collagen degradation by collagenase through an interleukin-1-mediated pathway. Arthritis Rheum. 46:2002;138-148.