-
2
-
-
0033816198
-
Targeting of epidermal growth factor receptor and protein kinase A: Molecular basis and therapeutic applications
-
(2000)
Ann. Oncol.
, vol.11
, pp. 777-783
-
-
Tortora, G.1
Ciardiello, F.2
-
3
-
-
0030614954
-
The RIα subunit of protein kinase A (PKA) binds to Grb2 and allows PKA interaction with the activated EGF-receptor
-
(1997)
Oncogene
, vol.14
, pp. 923-928
-
-
Tortora, G.1
Damiano, V.2
Bianco, C.3
Baldassarre, G.4
Bianco, A.R.5
Lanfrancone, L.6
Pelicci, P.G.7
Ciardiello, F.8
-
4
-
-
0027499522
-
Downregulation of RIα subunit of the cAMP-dependent protein kinase induces growth inhibition of human mammary epithelial cells transformed by c-Ha-ras and c-erbB2 protooncogenes
-
(1997)
Int. J. Cancer
, vol.53
, pp. 438-443
-
-
Ciardiello, F.1
Pepe, S.2
Bianco, C.3
Baldassarre, G.4
Ruggiero, A.5
Bianco, C.6
Selvam, M.P.7
Bianco, A.R.8
Tortora, G.9
-
7
-
-
0030729721
-
Synergistic inhibition of human cancer cell growth by cytotoxic drugs and mixed backbone antisense oligonucleotide targeting protein kinase A
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 12586-12591
-
-
Tortora, G.1
Caputo, R.2
Damiano, V.3
Bianco, R.4
Pepe, S.5
Bianco, A.R.6
Jiang, Z.7
Agrawal, S.8
Ciardiello, F.9
-
8
-
-
20244380289
-
A safety and pharmacokinetic study of a mixed-backbone oligonucleotide (GEM 231) targeting the type I protein kinase A by 2-hour infusions in patients with refractory solid tumors
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 1259-1266
-
-
Chen, H.X.1
Marshall, J.L.2
Ness, E.3
Martin, R.4
Dvorchik, B.5
Rizvi, N.6
Marquis, J.7
McKinlay, M.8
Dahut, W.9
Hawkins, M.J.10
-
10
-
-
0034130453
-
Oral antisense targeting protein kinase A cooperates with Taxol and inhibits tumor growth, angiogenesis, and growth factors production
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 2506-2512
-
-
Tortora, G.1
Bianco, R.2
Damiano, V.3
Fontanini, G.4
De Placido, S.5
Bianco, A.R.6
Ciardiello, F.7
-
13
-
-
0034068319
-
Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD1839 (Iressa), an EGFR-selective tyrosine kinase inhibitor
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 2053-2063
-
-
Ciardiello, F.1
Caputo, R.2
Bianco, R.3
Damiano, V.4
Pomatico, G.5
De Placido, S.6
Bianco, A.R.7
Tortora, G.8
-
14
-
-
16144362509
-
Antitumor activity of combined blockade of epidermal growth factor receptor and protein kinase A
-
(1996)
J. Natl. Cancer Inst. (Bethesda)
, vol.88
, pp. 1770-1776
-
-
Ciardiello, F.1
Damiano, V.2
Bianco, R.3
Bianco, C.4
Fontanini, G.5
De Laurentiis, M.6
De Placido, S.7
Mendelsohn, J.8
Bianco, A.R.9
Tortora, G.10
-
15
-
-
0032951396
-
Cooperative inhibitory effect of novel mixed backbone oligonucleotide targeting protein kinase A in combination with docetaxel and anti-epidermal growth factor receptor antibody on human breast cancer cell growth
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 875-881
-
-
Tortora, G.1
Caputo, R.2
Pomatico, G.3
Pepe, S.4
Bianco, A.R.5
Agrawal, S.6
Mendelsohn, J.7
Ciardiello, F.8
-
17
-
-
15444349941
-
Anti-proliferative activity of a new class of taxanes (14βhydroxy-10-deacetylbaccatin III derivatives) on multidrug-resistance-positive human cancer cells
-
(1997)
Int. J. Cancer
, vol.5
, pp. 844-850
-
-
Distefano, M.1
Scambia, G.2
Ferlini, C.3
Gaggini, C.4
De Vincenzo, R.5
Riva, A.6
Bombardelli, E.7
Ojima, I.8
Fattorossi, A.9
Panici, P.B.10
Mancuso, S.11
-
18
-
-
18844462763
-
Oral efficacy and bioavailability of a novel taxane
-
(2000)
Clin. Cancer Res.
, vol.5
, pp. 2070-2074
-
-
Polizzi, D.1
Pratesi, G.2
Monestiroli, S.3
Tortoreto, M.4
Zunino, F.5
Bombardelli, E.6
Riva, A.7
Morazzoni, P.8
Colombo, T.9
D’Incalci, M.10
Zucchetti, M.11
-
19
-
-
17344393983
-
IDN5109, a taxane with oral bioavailability and potent antitumor activity
-
(2000)
Cancer Res.
, vol.60
, pp. 842-846
-
-
Nicoletti, M.I.1
Colombo, T.2
Rossi, C.3
Monardo, C.4
Stura, S.5
Zucchetti, M.6
Riva, A.7
Morazzoni, P.8
Donati, M.B.9
Bombardelli, E.10
D’Incalci, M.11
Giavazzi, R.12
-
21
-
-
0029127219
-
Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors
-
(1995)
Breast Cancer Res. Treat.
, vol.36
, pp. 169-180
-
-
Weidner, N.1
-
22
-
-
0031907022
-
Evaluation of epidermal growth factor-related growth factors and receptors and of neoangiogenesis in completely resected stage I-IIIA non-small-cell lung cancer: Amphiregulin and microvessel count are independent prognostic indicators of survival
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 241-249
-
-
Fontanini, G.1
De Laurentiis, M.2
Vignati, S.3
Chinè, S.4
Lucchi, M.5
Silvestri, V.6
Mussi, A.7
De Placido, S.8
Tortora, G.9
Bianco, A.R.10
Gullick, W.11
Angeletti, C.A.12
Bevilacqua, G.13
Ciardiello, F.14
-
25
-
-
0032972944
-
Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 257-264
-
-
Perrotte, P.1
Matsumoto, T.2
Inoue, K.3
Kuniyasu, H.4
Eve, B.Y.5
Hicklin, D.J.6
Radinsky, R.7
Dinney, C.P.N.8
-
28
-
-
0031039923
-
Transforming growth factor α-induced transcriptional activation of the vascular permeability factor (VPF/VEGF) gene requires AP2-dependent DNA binding and transactivation
-
(1997)
EMBO J.
, vol.16
, pp. 750-759
-
-
Gille, J.1
Swerlick, R.A.2
Caughman, S.W.3
-
29
-
-
0033818695
-
Antiangiogenic and antitumor activity of anti-EGFR C225 monoclonal antibody in combination with vascular endothelial growth factor antisense oligonucleotide in human GEO colon cancer cells
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 3739-3747
-
-
Ciardiello, F.1
Bianco, R.2
Damiano, V.3
Fontanini, G.4
Caputo, R.5
Pomatico, G.6
De Placido, S.7
Bianco, A.R.8
Mendelsohn, J.9
Tortora, G.10
-
30
-
-
0034896362
-
Inhibition of growth factors production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 1459-1465
-
-
Ciardiello, F.1
Caputo, R.2
Bianco, R.3
Damiano, V.4
Fontanini, G.5
Cuccato, S.6
De Placido, S.7
Bianco, A.R.8
Tortora, G.9
-
31
-
-
0030888688
-
8-Chloro-cAMP inhibits autocrine and angiogenic growth factors production in human colorectal and breast cancer
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 439-448
-
-
Bianco, C.1
Tortora, G.2
Baldassarre, G.3
Caputo, R.4
Fontanini, G.5
Chinè, S.6
Bianco, A.R.7
Ciardiello, F.8
-
32
-
-
0029802685
-
The microtubule-affecting drug paclitaxel has antiangiogenic activity
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 1843-1849
-
-
Belotti, D.1
Vergani, V.2
Drudis, T.3
Borsotti, P.4
Pitelli, M.R.5
Viale, G.6
Giavazzi, R.7
Taraboletti, G.8
-
35
-
-
0034087691
-
Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity
-
(2000)
J. Clin. Investig.
, vol.105
, pp. 1115-1124
-
-
Klement, G.1
Baruchel, S.2
Rak, J.3
Man, S.4
Clark, K.5
Hicklin, D.J.6
Bohlen, P.7
Kerbel, R.S.8
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