Activation of nuclear factor-κB in the rabbit spinal cord following ischemia and reperfusion

Molecular Brain Research

Volumn 63, Issue 1, 1998, Pages 121-132

  Zhang, Shengjia ^a   Tobaru, Takaaki ^a   Zivin, Justin A ^a   Shackelford, Deborah A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Electrophoretic mobility shift assay; Ischemia; NF B; Stroke; Transcription factor

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; GENE EXPRESSION REGULATION; GENE INDUCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; SPINAL CORD ISCHEMIA;

ANIMALS; CEREBROVASCULAR DISORDERS; DISEASE MODELS, ANIMAL; DNA; DNA FRAGMENTATION; DNA PROBES; DNA-BINDING PROTEINS; GENE EXPRESSION; IN SITU HYBRIDIZATION; NF-KAPPA B; PARAPLEGIA; RABBITS; REPERFUSION INJURY; SPINAL CORD;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0032506690     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(98)00267-8     Document Type: Article

References (52)

1. Anderson C.W., Carter T.H. The DNA-activated protein kinase-DNA-PK. Current Topics Microbiol. Immunol. 217:1996;91-111.
2. Auphan N., DiDonato J.A., Rosette C., Helmberg A., Karin M. Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis. Science. 270:1995;286-290.
3. Baeuerle P.A., Baltimore D. Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor. Cell. 53:1988;211-217.
4. Baeuerle P.A., Baltimore D. NF-κB: Ten years after. Cell. 87:1996;13-20.
5. Baeuerle P.A., Henkel T. Function and activation of NF-κB in the immune system. Ann. Rev. Immunol. 12:1994;141-179.
6. 2+ accumulation. Proc. Natl. Acad. Sci. USA. 92:1995;9328-9332.
7. Barger S.W., Mattson M.P. Induction of neuroprotective κB-dependent transcription by secreted forms of the Alzheimer's β-amyloid precursor. Mol. Brain Res. 40:1996;116-126.
8. Beg A.A., Baltimore D. An essential role for NF-κB in preventing TNF-α-induced cell death. Science. 274:1996;782-784.
9. Bethea J.R., Castro M., Keane R.W., Lee T.T., Dietrich W.D., Yezierski R.P. Traumatic spinal cord injury induces nuclear factor-κB activation. J. Neurosci. 18:1998;3251-3260.
10. Bruce A.J., Boling W., Kindy M.S., Peschon J., Kraemer P.J., Carpenter M.K., Holtsberg F.W., Mattson M.P. Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors. Nature Med. 2:1996;788-794.
11. Cai Z., Körner M., Tarantino N., Chouaib S. IκBα overexpression in human breast carcinoma MCF7 cells inhibits nuclear factor-κB activation but not tumor necrosis factor-α-induced apoptosis. J. Biol. Chem. 272:1997;96-101.
12. Clark W.M., Madden K.P., Rothlein R., Zivin J.A. Reduction of central nervous system ischemic injury by monoclonal antibody to intercellular adhesion molecule. J. Neurosurg. 75:1991;623-627.
13. Clemens J.A., Stephenson D.T., Dixon E.P., Smalstig E.B., Mincy R.E., Rash K.S., Little S.P. Global cerebral ischemia activates nuclear factor-κB prior to evidence of DNA fragmentation. Mol. Brain Res. 48:1997;187-196.
14. Clemens J.A., Stephenson D.T., Smalstig E.B., Dixon E.P., Little S.P. Global ischemia activates nuclear factor-κB in forebrain neurons of rats. Stroke. 28:1997;1073-1081.
15. DeGirolami U., Zivin J.A. Neuropathology of experimental spinal cord ischemia in the rabbit. J. Neuropath. Expt. Neurol. 41:1982;129-149.
16. Dignam J.D., Lebovitz R.M., Roeder R.G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1983;1475-1489.
17. Du W., Thanos D., Maniatis T. Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements. Cell. 74:1993;887-898.
18. Feuerstein G.Z., Wang X., Barone F.C. Inflammatory gene expression in cerebral ischemia and trauma. Ann. NY Acad. Sci. 825:1997;179-193.
19. Grilli M., Pizzi M., Memo M., Spano P. Neuroprotection by aspirin and sodium salicylate through blockade of NF-kappa B activation. Science. 274:1996;1383-1385.
20. Héron A., Pollard H., Dessi F., Moreau J., Lasbennes F., Ben-Ari Y., Charriaut-Marlangue C. Regional variability in DNA fragmentation after global ischemia evidenced by combined histological and gel electrophoresis observations in the rat brain. J. Neurochem. 61:1993;1973-1976.
21. Hossmann K. Disturbances of cerebral protein synthesis and ischemic cell death. Progress in Brain Res. 96:1993;161-177.
22. Hsu H., Shu H.-B., Pan M.-G., Goeddel D.V. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell. 84:1996;299-308.
23. Jones P.L., Ping D., Boss J.M. Tumor necrosis factor alpha and interleukin-1β regulate the murine manganese superoxide dismutase gene through a complex intronic enhancer involving C/EBP-β and NF-kB. Mol. Cell. Biol. 17:1997;6970-6981.
24. Kaltschmidt C., Kaltschmidt B., Neumann H., Wekerle H., Baeuerle P.A. Constitutive NF-κB activity in neurons. Mol. Cell. Biol. 14:1994;3981-3992.
25. Kato H., Kanellopoulos G.K., Matsuo S., Wu Y.J., Jacquin M.F., Hsu C.Y., Kouchoukos N.T., Choi D.W. Neuronal apoptosis and necrosis following spinal cord ischemia in the rat. Exp. Neurol. 148:1997;464-474.
26. Klug J. Ku autoantigen is a potential major cause of nonspecific bands in electrophoretic mobility shift assays. Biotechniques. 22:1997;212-216.
27. Koide T., Wieloch T.W., Siesjö B.K. Chronic dexamethasone pretreatment aggravates ischemic neuronal necrosis. J. Cereb. Blood Flow Metab. 6:1986;395-404.
28. Kopp E., Ghosh S. Inhibition of NF-κB by sodium salicylate and aspirin. Science. 265:1994;956-959.
29. Laemmli U.K. Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
30. Lezoualc'h F., Sagara Y., Holsboer F., Behl C. High constitutive NF-κB activity mediates resistance to oxidative stress in neuronal cells. J. Neurosci. 18:1998;3224-3232.
31. Li Y., Chopp M., Jiang N., Yao F., Zaloga C. Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat. J. Cereb. Blood Flow Metab. 15:1995;389-397.
32. Linnik M.D., Zobrist R.H., Hatfield M.D. Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats. Stroke. 24:1993;2002-2009.
33. Liu Z.-G., Hsu H., Goeddel D.V., Karin M. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death. Cell. 87:1996;565-576.
34. Mackey M.E., Wu Y., Hu R., DeMaro J.A., Jacquin M.F., Kanellopoulos G.K., Hsu S.Y., Kouchoukos N.T. Cell death suggestive of apoptosis after spinal cord ischemia in rabbits. Stroke. 28:1997;2012-2017.
35. MacManus J.P., Buchan A.M., Hill I.E., Rasquinha I., Preston E. Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain. Neurosci. Lett. 164:1993;89-92.
36. Nawashiro H., Tasaki K., Ruetzler C.A., Hallenbeck J.M. TNF-α pretreatment induces protective effects against focal cerebral ischemia in mice. J. Cereb. Blood Flow Metab. 17:1997;483-490.
37. O'Neill L.A.J., Kaltschmidt C. NF-κB: a crucial transcription factor for glial and neuronal cell function. Trends Neurosci. 20:1997;252-258.
38. Petito C.K., Torres-Munoz J., Roberts B., Olarte J.-P., Nowak T.S. Jr., Pulsinelli W.A. DNA fragmentation follows delayed neuronal death in CA1 neurons exposed to transient global ischemia in the rat. J. Cereb. Blood Flow Metab. 17:1997;967-976.
39. Ponton A., Clément M.-V., Stamenkovic I. The CD95 (APO-1/Fas) receptor activates NF-kB independently of cytotoxic function. J. Biol. Chem. 271:1996;8991-8995.
40. Salminen A., Liu P.K., Hsu C.Y. Alteration of transcription factor binding activities in the ischemic rat brain. Biochem. Biophys. Res. Commun. 212:1995;939-944.
41. Sapolsky R.M., Pulsinelli W.A. Glucocorticoids potentiate ischemic injury to neurons: Therapeutic implications. Science. 229:1985;1397-1400.
42. Scheinman R.I., Cogswell P.C., Lofquist A.K., Baldwin A.S. Jr. Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids. Science. 270:1995;283-286.
43. Stein B., Baldwin A.S. Jr., Ballard D.W., Greene W.C., Angel P., Herrlich P. Cross-coupling of the NF-κB p65 and Fos/Jun transcription factors produces potentiated biological function. EMBO J. 12:1993;3879-3891.
44. Taglialatela G., Robinson R., Perez-Polo J.R. Inhibition of nuclear factor kappa B (NF-κB) activity induces nerve growth factor-resistant apoptosis in PC12 cells. J. Neurosci. Res. 47:1997;155-162.
45. Tominaga T., Kure S., Narisawa K., Yoshimoto T. Endonuclease activation following focal ischemic injury in the rat brain. Brain Res. 608:1993;21-26.
46. Van Antwerp D., Martin S.J., Kafri T., Green D.R., Verma I.M. Suppression of TNF-α-induced apoptosis by NF-κB. Science. 274:1996;787-789.
47. Wang C.-Y., Mayo M.W., Baldwin A.S. Jr. TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB. Science. 274:1996;784-787.
48. Wong G.H.W., Elwell J.H., Oberley L.W., Goeddel D.V. Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor. Cell. 58:1989;923-931.
49. Wu M., Lee H., Bellas R.E., Schauer S.L., Arsura M., Katz D., FitzGerald M.J., Rothstein T.L., Sherr D.H., Sonenshein G.E. Inhibition of NF-κB/Rel induces apoptosis of murine B cells. EMBO J. 15:1996;4682-4690.
50. Yang K., Mu X.S., Hayes R.L. Increased cortical nuclear factor-κB (NF-κB) DNA binding activity after traumatic brain injury in rats. Neurosci. Lett. 197:1995;101-104.
51. Zivin J.A., DeGirolami U. Studies of the influence of biogenic amines on central nervous system ischemia. Stroke. 17:1986;509-516.
52. Zivin J.A., DeGirolami U., Hurwitz E.L. A quantitative study of the spectrum of neurological deficits in experimental nervous system ischemia. Arch. Neurol. 39:1982;408-412.