Using nondenaturing mass spectrometry to detect fortuitous ligands in orphan nuclear receptors

Protein Science

Volumn 12, Issue 4, 2003, Pages 725-733

  Potier, Noelle ^a   Billas, Isabelle M L ^b   Steinmetz, Anke ^b   Schaeffer, Christine ^a   Van Dorsselaer, Alain ^a   Moras, Dino ^b   Renaud, Jean Paul ^b  

^a Lab Spectrom Masse Bio Organique   (France)

^b INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Electrospray mass spectrometry; Fortuitous ligand; Noncovalent interactions; Nuclear receptor; Orphan receptor; ROR; USP

Indexed keywords

CELL NUCLEUS RECEPTOR; LIGAND; PROTEIN; RETINOIC ACID RELATED ORPHAN RECEPTOR BETA; ULTRASPIRACLE PROTEIN; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; EXTRACTION; HOST CELL; LIGAND BINDING; MASS SPECTROMETRY; MOLECULE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; STOICHIOMETRY;

ANIMALS; LIGANDS; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 0037379181     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.0232503     Document Type: Article

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