Regulation of cellular glutathione modulates nuclear accumulation of daunorubicin in human MCF7 cells overexpressing multidrug resistance associated protein

European Journal of Cancer

Volumn 36, Issue 3, 2000, Pages 428-434

  Benderra, Z ^a   Trussardi, A ^b   Morjani, H ^a   Villa, A M ^c   Doglia, S M ^c   Manfait, M ^a  

^a UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

^b INSTITUT JEAN GODINOT   (France)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

Anthracyclines; Buthionine sulphoximine; Confocal microscopy; Flow cytometry; Glutathione; Microspectrofluorometry; MRP1; P glycoprotein; RT PCR

Indexed keywords

BUTHIONINE SULFOXIMINE; DAUNORUBICIN; DOXORUBICIN; ETOPOSIDE; GLUTATHIONE; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN;

ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACCUMULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SPECTROFLUOROMETRY; TECHNIQUE; TUMOR CELL LINE;

ANTIBIOTICS, ANTINEOPLASTIC; ATP-BINDING CASSETTE TRANSPORTERS; BREAST NEOPLASMS; BUTHIONINE SULFOXIMINE; CELL NUCLEUS; DAUNORUBICIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; ENZYME INHIBITORS; ETOPOSIDE; FEMALE; FLOW CYTOMETRY; GLUTATHIONE; GLUTATHIONE SYNTHASE; HUMANS; MICROSCOPY, CONFOCAL; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECTROMETRY, FLUORESCENCE; TUMOR CELLS, CULTURED;

EID: 0034002720     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(99)00288-9     Document Type: Article

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