-
1
-
-
0014190760
-
Self-replication and scrapie
-
Griffith JS. Self-replication and scrapie. Nature 1967;215:1043-4.
-
(1967)
Nature
, vol.215
, pp. 1043-1044
-
-
Griffith, J.S.1
-
2
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
Prusiner SB. Novel proteinaceous infectious particles cause scrapie. Science 1982; 216:136-44.
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
3
-
-
0035957345
-
Ex vivo propagation of infectious sheep scrapie agent in heterologous epithelial cells expressing ovine prion protein
-
Vilette D, Andreoletti O, Archer F, et al. Ex vivo propagation of infectious sheep scrapie agent in heterologous epithelial cells expressing ovine prion protein. Proc Natl Acad Sci USA 2001;98:4055-9.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4055-4059
-
-
Vilette, D.1
Andreoletti, O.2
Archer, F.3
-
4
-
-
0027956109
-
Cell-free formation of protease-resistant prion protein
-
Kocisko DA, Come JH, Priola SA, et al. Cell-free formation of protease-resistant prion protein. Nature 1994;370:471-4.
-
(1994)
Nature
, vol.370
, pp. 471-474
-
-
Kocisko, D.A.1
Come, J.H.2
Priola, S.A.3
-
5
-
-
0035859102
-
Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding
-
Saborio GP, Permanne B, Soto C. Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. Nature 2001;411:810-3.
-
(2001)
Nature
, vol.411
, pp. 810-813
-
-
Saborio, G.P.1
Permanne, B.2
Soto, C.3
-
6
-
-
0033542142
-
Cell-lysate conversion of prion protein into its protease-resistant isoform suggests the participation of a cellular chaperone
-
Saborio GP, Soto C, Kascsak RJ, et al. Cell-lysate conversion of prion protein into its protease-resistant isoform suggests the participation of a cellular chaperone. Biochem Biophys Res Commun 1999;258:470-5.
-
(1999)
Biochem Biophys Res Commun
, vol.258
, pp. 470-475
-
-
Saborio, G.P.1
Soto, C.2
Kascsak, R.J.3
-
7
-
-
0028997297
-
Non-genetic propagation of strain-specific properties of scrapie prion protein
-
Bessen RA, Kocisko DA, Raymond GJ, et al. Non-genetic propagation of strain-specific properties of scrapie prion protein. Nature 1995;375:698-700.
-
(1995)
Nature
, vol.375
, pp. 698-700
-
-
Bessen, R.A.1
Kocisko, D.A.2
Raymond, G.J.3
-
8
-
-
0031000201
-
Scrapie susceptibility-linked polymorphisms modulate the in vitro conversion of sheep prion protein to protease-resistant forms
-
Bossers A, Belt PBGM, Raymond GJ, et al. Scrapie susceptibility-linked polymorphisms modulate the in vitro conversion of sheep prion protein to protease-resistant forms. Proc Natl Acad Sci USA 1997;94:4931-6.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4931-4936
-
-
Bossers, A.1
Belt, P.B.G.M.2
Raymond, G.J.3
-
9
-
-
0033982338
-
Susceptibility of sheep for scrapie as assessed by in vitro conversion of nine naturally occurring variants of PrP
-
Bossers A, de Vries R, Smits MA. Susceptibility of sheep for scrapie as assessed by in vitro conversion of nine naturally occurring variants of PrP. J Virol 2000;74: 1407-14.
-
(2000)
J Virol
, vol.74
, pp. 1407-1414
-
-
Bossers, A.1
De Vries, R.2
Smits, M.A.3
-
10
-
-
0029066886
-
Species specificity in the cell-free conversion of prion protein to protease-resistant forms: A model for the scrapie species barrier
-
Kocisko DA, Priola SA, Raymond GJ, et al. Species specificity in the cell-free conversion of prion protein to protease-resistant forms: a model for the scrapie species barrier. Proc Natl Acad Sci USA 1995;92:3923-7.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3923-3927
-
-
Kocisko, D.A.1
Priola, S.A.2
Raymond, G.J.3
-
11
-
-
0030802361
-
Molecular assessment of the potential transmissibilities of BSE and scrapie to humans
-
Raymond GJ, Hope J, Kocisko DA, et al. Molecular assessment of the potential transmissibilities of BSE and scrapie to humans. Nature 1997;388:285-8.
-
(1997)
Nature
, vol.388
, pp. 285-288
-
-
Raymond, G.J.1
Hope, J.2
Kocisko, D.A.3
-
12
-
-
0034282971
-
Evidence of a molecular barrier limiting susceptibility of humans, cattle and sheep to chronic wasting disease
-
Raymond GJ, Bossers A, Raymond LD, et al. Evidence of a molecular barrier limiting susceptibility of humans, cattle and sheep to chronic wasting disease. EMBO J 2000; 19:4425-30.
-
(2000)
EMBO J
, vol.19
, pp. 4425-4430
-
-
Raymond, G.J.1
Bossers, A.2
Raymond, L.D.3
-
13
-
-
0016863344
-
Letter: Interspecies transmission of scrapie-like diseases
-
Kimberlin RH, Walker CA, Millson GC. Letter: interspecies transmission of scrapie-like diseases. Lancet 1975;2:1309-10.
-
(1975)
Lancet
, vol.2
, pp. 1309-1310
-
-
Kimberlin, R.H.1
Walker, C.A.2
Millson, G.C.3
-
14
-
-
0032488777
-
A transmembrane form of the prion protein in neurodegenerative disease
-
Hegde RS, Mastrianni JA, Scott MR, et al. A transmembrane form of the prion protein in neurodegenerative disease. Science 1998;279:827-34.
-
(1998)
Science
, vol.279
, pp. 827-834
-
-
Hegde, R.S.1
Mastrianni, J.A.2
Scott, M.R.3
-
15
-
-
0035910518
-
Most pathogenic mutations do not alter the membrane topology of the prion protein
-
Stewart RS, Harris DA. Most pathogenic mutations do not alter the membrane topology of the prion protein. J Biol Chem 2001;276:2212-20.
-
(2001)
J Biol Chem
, vol.276
, pp. 2212-2220
-
-
Stewart, R.S.1
Harris, D.A.2
-
16
-
-
0030050733
-
Mutant and infectious prion proteins display common biochemical properties in cultured cells
-
Lehmann S, Harris DA. Mutant and infectious prion proteins display common biochemical properties in cultured cells. J Biol Chem 1996;271:1633-7.
-
(1996)
J Biol Chem
, vol.271
, pp. 1633-1637
-
-
Lehmann, S.1
Harris, D.A.2
-
17
-
-
0025910229
-
Molecular biology of prion diseases
-
Prusiner SB. Molecular biology of prion diseases. Science 1991;252:1515-22.
-
(1991)
Science
, vol.252
, pp. 1515-1522
-
-
Prusiner, S.B.1
-
18
-
-
0027270578
-
A kinetic model for amyloid formation in the prion diseases: Importance of seeding
-
Come JH, Fraser PE, Lansbury PT. A kinetic model for amyloid formation in the prion diseases: importance of seeding. Proc Natl Acad Sci USA 1993;90:5959-63.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 5959-5963
-
-
Come, J.H.1
Fraser, P.E.2
Lansbury, P.T.3
-
19
-
-
0027195933
-
Seeding "one-dimensional crystallization" of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?
-
Jarrett JT, Lansbury PT Jr. Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie? Cell 1993;73:1055-8.
-
(1993)
Cell
, vol.73
, pp. 1055-1058
-
-
Jarrett, J.T.1
Lansbury P.T., Jr.2
-
20
-
-
0029583794
-
Aggregates of scrapie-associated prion protein induce the cell-free conversion of protease-sensitive prion protein to the protease-resistant state
-
Caughey B, Kocisko DA, Raymond GJ, et al. Aggregates of scrapie-associated prion protein induce the cell-free conversion of protease-sensitive prion protein to the protease-resistant state. Chem Biol 1995;2:807-17.
-
(1995)
Chem Biol
, vol.2
, pp. 807-817
-
-
Caughey, B.1
Kocisko, D.A.2
Raymond, G.J.3
-
21
-
-
0030944992
-
Scrapie infectivity correlates with converting activity, protease resistance, and aggregation of scrapie-associated prion protein in guanidine denaturation studies
-
Caughey B, Raymond GJ, Kocisko DA, et al. Scrapie infectivity correlates with converting activity, protease resistance, and aggregation of scrapie-associated prion protein in guanidine denaturation studies. J Virol 1997;71:4107-10.
-
(1997)
J Virol
, vol.71
, pp. 4107-4110
-
-
Caughey, B.1
Raymond, G.J.2
Kocisko, D.A.3
-
22
-
-
0024211952
-
Transmissible and non-transmissible amyloidoses: Autocatalytic post-translational conversion of host precursor proteins to beta-pleated sheet configurations
-
Gajdusek DC. Transmissible and non-transmissible amyloidoses: autocatalytic post-translational conversion of host precursor proteins to beta-pleated sheet configurations. J Neuroimmunol 1988;20:95-110.
-
(1988)
J Neuroimmunol
, vol.20
, pp. 95-110
-
-
Gajdusek, D.C.1
-
23
-
-
0029819057
-
Partial unfolding and refolding of scrapie-associated prion protein: Evidence for a critical 16-kDa C-terminal domain
-
Kocisko DA, Lansbury PT Jr, Caughey B. Partial unfolding and refolding of scrapie-associated prion protein: evidence for a critical 16-kDa C-terminal domain. Biochem 1996;35:13434-42.
-
(1996)
Biochem
, vol.35
, pp. 13434-13442
-
-
Kocisko, D.A.1
Lansbury P.T., Jr.2
Caughey, B.3
-
24
-
-
0029110883
-
The chemistry of scrapie infection: Implications of the "ice 9" metaphor
-
Lansbury PT Jr, Caughey B. The chemistry of scrapie infection: implications of the "ice 9" metaphor. Chem Biol 1995;2:1-5.
-
(1995)
Chem Biol
, vol.2
, pp. 1-5
-
-
Lansbury P.T., Jr.1
Caughey, B.2
-
25
-
-
0028867086
-
Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform
-
Kaneko K, Peretz D, Pan KM, et al. Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform. Proc Natl Acad Sci USA 1995;92: 11160-11164.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 11160-11164
-
-
Kaneko, K.1
Peretz, D.2
Pan, K.M.3
-
26
-
-
0026062496
-
Scrapie prion rod formation in vitro requires both detergent extraction and limited proteolysis
-
McKinley MP, Meyer RK, Kenaga L, et al. Scrapie prion rod formation in vitro requires both detergent extraction and limited proteolysis. J Virol 1991;65:1340-51.
-
(1991)
J Virol
, vol.65
, pp. 1340-1351
-
-
McKinley, M.P.1
Meyer, R.K.2
Kenaga, L.3
-
27
-
-
0032802332
-
Cellular biology of prion diseases
-
Harris DA. Cellular biology of prion diseases. Clin Microbiol Rev 1999;12:429-44.
-
(1999)
Clin Microbiol Rev
, vol.12
, pp. 429-444
-
-
Harris, D.A.1
-
28
-
-
0033597931
-
Sphingolipid depletion increases formation of the scrapie prion protein in neuroblastoma cells infected with prions
-
Naslavsky N, Shmeeda H, Friedlander G, et al. Sphingolipid depletion increases formation of the scrapie prion protein in neuroblastoma cells infected with prions. J Biol Chem 1999;274:20763-71.
-
(1999)
J Biol Chem
, vol.274
, pp. 20763-20771
-
-
Naslavsky, N.1
Shmeeda, H.2
Friedlander, G.3
-
29
-
-
0036500554
-
Conversion of raft associated prion protein to the protease-resistant state requires insertion of PrP-res (PrP(Sc)) into contiguous membranes
-
Baron GS, Wehrly K, Dorward DW, et al. Conversion of raft associated prion protein to the protease-resistant state requires insertion of PrP-res (PrP(Sc)) into contiguous membranes. EMBO J 2002;21:1031-40.
-
(2002)
EMBO J
, vol.21
, pp. 1031-1040
-
-
Baron, G.S.1
Wehrly, K.2
Dorward, D.W.3
-
30
-
-
0033567955
-
Characterization and polyanion-binding properties of purified recombinant prion protein
-
Brimacombe DB, Bennett AD, Wusteman FS, et al. Characterization and polyanion-binding properties of purified recombinant prion protein. Biochem J 1999;342(Pt 3):605-13.
-
(1999)
Biochem J
, vol.342
, Issue.PART 3
, pp. 605-613
-
-
Brimacombe, D.B.1
Bennett, A.D.2
Wusteman, F.S.3
-
31
-
-
0027280172
-
Congo red inhibition of scrapie agent replication
-
Caughey B, Ernst D, Race RE. Congo red inhibition of scrapie agent replication. J Virol 1993;67:6270-2.
-
(1993)
J Virol
, vol.67
, pp. 6270-6272
-
-
Caughey, B.1
Ernst, D.2
Race, R.E.3
-
32
-
-
0030894380
-
Characterization of detergent-insoluble complexes containing the cellular prion protein and its scrapie isoform
-
Naslavsky N, Stein R, Yanai A, et al. Characterization of detergent-insoluble complexes containing the cellular prion protein and its scrapie isoform. J Biol Chem 1997;272:6324-31.
-
(1997)
J Biol Chem
, vol.272
, pp. 6324-6331
-
-
Naslavsky, N.1
Stein, R.2
Yanai, A.3
-
34
-
-
0028882424
-
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
-
Telling GC, Scott M, Mastrianni J, et al. Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein. Cell 1995;83:79-90.
-
(1995)
Cell
, vol.83
, pp. 79-90
-
-
Telling, G.C.1
Scott, M.2
Mastrianni, J.3
-
35
-
-
0031443433
-
Chaperone-supervised conversion of prion protein to its protease-resistant form
-
DebBurman SK, Raymond GJ, Caughey B, et al. Chaperone-supervised conversion of prion protein to its protease-resistant form. Proc Natl Acad Sci USA 1997;94:13938-43.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 13938-13943
-
-
DebBurman, S.K.1
Raymond, G.J.2
Caughey, B.3
-
36
-
-
0034916581
-
Prion diseases of humans and animals: Their causes and molecular basis
-
Collinge J. Prion diseases of humans and animals: their causes and molecular basis. Annu Rev Neurosci 2001;24:519-50.
-
(2001)
Annu Rev Neurosci
, vol.24
, pp. 519-550
-
-
Collinge, J.1
-
37
-
-
0033130083
-
Strain-specific prion-protein conformation determined by metal ions
-
Wadsworth JD, Hill AF, Joiner S, et al. Strain-specific prion-protein conformation determined by metal ions. Nat Cell Biol 1999;1:55-9.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 55-59
-
-
Wadsworth, J.D.1
Hill, A.F.2
Joiner, S.3
-
38
-
-
0023928927
-
Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins
-
Butler DA, Scott MR, Bockman JM, et al. Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins. J Virol 1988;62:1558-64.
-
(1988)
J Virol
, vol.62
, pp. 1558-1564
-
-
Butler, D.A.1
Scott, M.R.2
Bockman, J.M.3
-
39
-
-
0023785139
-
Analyses of frequency of infection, specific infectivity, and prion protein biosynthesis in scrapie-infected neuroblastoma cell clones
-
Race RE, Caughey B, Graham K, et al. Analyses of frequency of infection, specific infectivity, and prion protein biosynthesis in scrapie-infected neuroblastoma cell clones. J Virol 1988;62:2845-9.
-
(1988)
J Virol
, vol.62
, pp. 2845-2849
-
-
Race, R.E.1
Caughey, B.2
Graham, K.3
-
40
-
-
0023091197
-
Characterization of scrapie infection in mouse neuroblastoma cells
-
Race RE, Fadness LH, Chesebro B. Characterization of scrapie infection in mouse neuroblastoma cells. J Gen Virol 1987;68(Pt 5):1391-9.
-
(1987)
J Gen Virol
, vol.68
, Issue.PART 5
, pp. 1391-1399
-
-
Race, R.E.1
Fadness, L.H.2
Chesebro, B.3
-
41
-
-
0033988236
-
Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein
-
Nishida N, Harris DA, Vilette D, et al. Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein. J Virol 2000;74:320-5.
-
(2000)
J Virol
, vol.74
, pp. 320-325
-
-
Nishida, N.1
Harris, D.A.2
Vilette, D.3
-
42
-
-
0028364192
-
Heterologous PrP molecules interfere with accumulation of protease-resistant PrP in scrapie-infected murine neuroblastoma cells
-
Priola SA, Caughey B, Race RE, et al. Heterologous PrP molecules interfere with accumulation of protease-resistant PrP in scrapie-infected murine neuroblastoma cells. J Virol 1994;68:4873-8.
-
(1994)
J Virol
, vol.68
, pp. 4873-4878
-
-
Priola, S.A.1
Caughey, B.2
Race, R.E.3
-
43
-
-
0025304678
-
Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells
-
Borchelt DR, Scott M, Taraboulos A, et al. Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells. J Cell Biol 1990;110:743-52.
-
(1990)
J Cell Biol
, vol.110
, pp. 743-752
-
-
Borchelt, D.R.1
Scott, M.2
Taraboulos, A.3
-
44
-
-
0023803281
-
In vitro expression in eukaryotic cells of a prion protein gene cloned from scrapie-infected mouse brain
-
Caughey B, Race RE, Vogel M, et al. In vitro expression in eukaryotic cells of a prion protein gene cloned from scrapie-infected mouse brain. Proc Natl Acad Sci USA 1988;85: 4657-4661.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 4657-4661
-
-
Caughey, B.1
Race, R.E.2
Vogel, M.3
-
45
-
-
0025991466
-
The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive
-
Caughey B, Raymond GJ. The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive. J Biol Chem 1991; 266:18217-23.
-
(1991)
J Biol Chem
, vol.266
, pp. 18217-18223
-
-
Caughey, B.1
Raymond, G.J.2
-
46
-
-
0001568413
-
Cellular metabolism of normal and scrapie-associated forms of PrP
-
Caughey B. Cellular metabolism of normal and scrapie-associated forms of PrP. Semin Virol 1991;2:189-96.
-
(1991)
Semin Virol
, vol.2
, pp. 189-196
-
-
Caughey, B.1
-
47
-
-
0025876226
-
N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease(s): Implications regarding the site of conversion of PrP to the protease-resistant state
-
Caughey B, Raymond GJ, Ernst D, et al. N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease(s): implications regarding the site of conversion of PrP to the protease-resistant state. J Virol 1991;65:6597-603.
-
(1991)
J Virol
, vol.65
, pp. 6597-6603
-
-
Caughey, B.1
Raymond, G.J.2
Ernst, D.3
-
48
-
-
0033978718
-
Inhibition of prion-protein conversion: A therapeutic tool?
-
Head MW, Ironside JW. Inhibition of prion-protein conversion: a therapeutic tool? Trends Microbiol 2000;8:6-8.
-
(2000)
Trends Microbiol
, vol.8
, pp. 6-8
-
-
Head, M.W.1
Ironside, J.W.2
-
49
-
-
0033081356
-
Prion protein and species barriers in the transmissible spongiform encephalopathies
-
Priola SA. Prion protein and species barriers in the transmissible spongiform encephalopathies. Biomed Pharmacother 1999;53:27-33.
-
(1999)
Biomed Pharmacother
, vol.53
, pp. 27-33
-
-
Priola, S.A.1
-
50
-
-
0031594587
-
Overexpression of nonconvertible PrPc delta 114-121 in scrapie-infected mouse neuroblastoma cells leads to trans-dominant inhibition of wild- type PrP(Sc) accumulation
-
Holscher C, Delius H, Burkle A. Overexpression of nonconvertible PrPc delta 114-121 in scrapie-infected mouse neuroblastoma cells leads to trans-dominant inhibition of wild- type PrP(Sc) accumulation. J Virol 1998;72:1153-9.
-
(1998)
J Virol
, vol.72
, pp. 1153-1159
-
-
Holscher, C.1
Delius, H.2
Burkle, A.3
-
51
-
-
0025373111
-
Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells
-
Taraboulos A, Serban D, Prusiner SB. Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells. J Cell Biol 1990;110:2117-32.
-
(1990)
J Cell Biol
, vol.110
, pp. 2117-2132
-
-
Taraboulos, A.1
Serban, D.2
Prusiner, S.B.3
-
52
-
-
0021745705
-
In vitro replication of scrapie agent in a neuronal model: Infection of PC12 cells
-
Rubenstein R, Carp RI, Callahan SM. In vitro replication of scrapie agent in a neuronal model: infection of PC12 cells. J Gen Virol 1984;65(Pt 12):2191-8.
-
(1984)
J Gen Virol
, vol.65
, Issue.PART 12
, pp. 2191-2198
-
-
Rubenstein, R.1
Carp, R.I.2
Callahan, S.M.3
-
53
-
-
0037611374
-
A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis
-
Schatzl HM, Laszlo L, Holtzman DM, et al. A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis. J Virol 1997;71:8821-31.
-
(1997)
J Virol
, vol.71
, pp. 8821-8831
-
-
Schatzl, H.M.1
Laszlo, L.2
Holtzman, D.M.3
-
54
-
-
0033564204
-
Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state
-
Horiuchi M, Caughey B. Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state. EMBO J 1999; 8:3193-203.
-
(1999)
EMBO J
, vol.8
, pp. 3193-3203
-
-
Horiuchi, M.1
Caughey, B.2
-
55
-
-
0034705020
-
Interactions between heterologous forms of prion protein: Binding, inhibition of conversion, and species barriers
-
Horiuchi M, Priola SA, Chabry J, et al. Interactions between heterologous forms of prion protein: binding, inhibition of conversion, and species barriers. Proc Natl Acad Sci USA 2000;97:5836-41.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5836-5841
-
-
Horiuchi, M.1
Priola, S.A.2
Chabry, J.3
-
56
-
-
0032514682
-
Inhibition of protease-resistant prion protein formation by porphyrins and phthalocyanines
-
Caughey WS, Raymond LD, Horiuchi M, et al. Inhibition of protease-resistant prion protein formation by porphyrins and phthalocyanines. Proc Natl Acad Sci USA 1998; 95:12117-22.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 12117-12122
-
-
Caughey, W.S.1
Raymond, L.D.2
Horiuchi, M.3
-
57
-
-
0032557457
-
Specific inhibition of in vitro formation of protease-resistant prion protein by synthetic peptides
-
Chabry J, Caughey B, Chesebro B. Specific inhibition of in vitro formation of protease-resistant prion protein by synthetic peptides. J Biol Chem 1998;273:13203-7.
-
(1998)
J Biol Chem
, vol.273
, pp. 13203-13207
-
-
Chabry, J.1
Caughey, B.2
Chesebro, B.3
-
58
-
-
0032775473
-
Species-independent inhibition of abnormal prion protein (PrP) formation by a peptide containing a conserved PrP sequence
-
Chabry J, Priola SA, Wehrly K, et al. Species-independent inhibition of abnormal prion protein (PrP) formation by a peptide containing a conserved PrP sequence. J Virol 1999; 73:6245-50.
-
(1999)
J Virol
, vol.73
, pp. 6245-6250
-
-
Chabry, J.1
Priola, S.A.2
Wehrly, K.3
-
59
-
-
28444498432
-
Inhibition of formation of protease-resistant prion protein by trypan blue, sirius red and other Congo red analogs
-
Demaimay R, Chesebro B, Caughey B. Inhibition of formation of protease-resistant prion protein by trypan blue, sirius red and other Congo red analogs. Arch Virol 2000; (Suppl 16):277-83.
-
(2000)
Arch Virol
, Issue.SUPPL. 16
, pp. 277-283
-
-
Demaimay, R.1
Chesebro, B.2
Caughey, B.3
-
60
-
-
0032892306
-
Protease-resistant prion protein produced in vitro lacks detectable infectivity
-
Hill AF, Antoniou M, Collinge J. Protease-resistant prion protein produced in vitro lacks detectable infectivity. J Gen Virol 1999;80(Pt 1):11-4.
-
(1999)
J Gen Virol
, vol.80
, Issue.PART 1
, pp. 11-14
-
-
Hill, A.F.1
Antoniou, M.2
Collinge, J.3
-
61
-
-
28444457804
-
Quantitative traits of prion strains are enciphered in the conformation of the prion protein
-
Safar J, Cohen FE, Prusiner SB. Quantitative traits of prion strains are enciphered in the conformation of the prion protein. Arch Virol 2000;(Suppl):227-35.
-
(2000)
Arch Virol
, Issue.SUPPL.
, pp. 227-235
-
-
Safar, J.1
Cohen, F.E.2
Prusiner, S.B.3
-
62
-
-
0031720905
-
Eight prion strains have PrP(Sc) molecules with different conformations
-
Safar J, Wille H, Itri V, et al. Eight prion strains have PrP(Sc) molecules with different conformations. Nat Med 1998;4:1157-65.
-
(1998)
Nat Med
, vol.4
, pp. 1157-1165
-
-
Safar, J.1
Wille, H.2
Itri, V.3
-
63
-
-
0035086136
-
Strain-specified relative conformational stability of the scrapie prion protein
-
Peretz D, Scott MR, Groth D, et al. Strain-specified relative conformational stability of the scrapie prion protein. Protein Sci 2001;10:854-63.
-
(2001)
Protein Sci
, vol.10
, pp. 854-863
-
-
Peretz, D.1
Scott, M.R.2
Groth, D.3
-
64
-
-
0033610870
-
Strain-dependent differences in beta-sheet conformations of abnormal prion protein
-
Caughey B, Raymond GJ, Bessen RA. Strain-dependent differences in beta-sheet conformations of abnormal prion protein. J Biol Chem 1998;273:32230-5.
-
(1998)
J Biol Chem
, vol.273
, pp. 32230-32235
-
-
Caughey, B.1
Raymond, G.J.2
Bessen, R.A.3
-
65
-
-
0026583834
-
Biochemical and physical properties of the prion protein from two strains of the transmissible mink encephalopathy agent
-
Bessen RA, Marsh RF. Biochemical and physical properties of the prion protein from two strains of the transmissible mink encephalopathy agent. J Virol 1992;66: 2096-101.
-
(1992)
J Virol
, vol.66
, pp. 2096-2101
-
-
Bessen, R.A.1
Marsh, R.F.2
-
66
-
-
0028043661
-
Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy
-
Bessen RA, Marsh RF. Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy. J Virol 1994;68:7859-68.
-
(1994)
J Virol
, vol.68
, pp. 7859-7868
-
-
Bessen, R.A.1
Marsh, R.F.2
-
67
-
-
0024276258
-
The unusual properties of CH1641, a sheep-passaged isolate of scrapie
-
Foster JD, Dickinson AG. The unusual properties of CH1641, a sheep-passaged isolate of scrapie. Vet Rec 1988;123:5-8.
-
(1988)
Vet Rec
, vol.123
, pp. 5-8
-
-
Foster, J.D.1
Dickinson, A.G.2
-
68
-
-
0013894656
-
The relative susceptibility of sheep, goats and mice to two types of the goat scrapie agent
-
Pattison IH. The relative susceptibility of sheep, goats and mice to two types of the goat scrapie agent. Res Vet Sci 1966;7:207-12.
-
(1966)
Res Vet Sci
, vol.7
, pp. 207-212
-
-
Pattison, I.H.1
-
69
-
-
0024330055
-
Primary structure of prion protein may modify scrapie isolate properties
-
Carlson GA, Westaway D, DeArmond SJ, et al. Primary structure of prion protein may modify scrapie isolate properties. Proc Natl Acad Sci USA 1989;86:7475-9.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 7475-7479
-
-
Carlson, G.A.1
Westaway, D.2
DeArmond, S.J.3
-
70
-
-
0028349264
-
PrP genotype and agent effects in scrapie: Change in allelic interaction with different isolates of agent in sheep, a natural host of scrapie
-
Goldmann W, Hunter N, Smith G, et al. PrP genotype and agent effects in scrapie: change in allelic interaction with different isolates of agent in sheep, a natural host of scrapie. J Gen Virol 1994;75:989-95.
-
(1994)
J Gen Virol
, vol.75
, pp. 989-995
-
-
Goldmann, W.1
Hunter, N.2
Smith, G.3
-
71
-
-
0035041973
-
Efficient conversion of normal prion protein (PrP) by abnormal hamster PrP is determined by homology at amino acid residue 155
-
Priola SA, Chabry J, Chan K. Efficient conversion of normal prion protein (PrP) by abnormal hamster PrP is determined by homology at amino acid residue 155. J Virol 2001;75:4673-80.
-
(2001)
J Virol
, vol.75
, pp. 4673-4680
-
-
Priola, S.A.1
Chabry, J.2
Chan, K.3
-
72
-
-
0028103792
-
Prion protein and the scrapie agent: In vitro studies in infected neuroblastoma cells
-
Priola SA, Caughey B, Raymond GJ, et al. Prion protein and the scrapie agent: in vitro studies in infected neuroblastoma cells. Infect Agents Dis 1994;3:54-8.
-
(1994)
Infect Agents Dis
, vol.3
, pp. 54-58
-
-
Priola, S.A.1
Caughey, B.2
Raymond, G.J.3
-
73
-
-
0028874320
-
A 60-kDa prion protein (PrP) with properties of both the normal and scrapie-associated forms of PrP
-
Priola SA, Caughey B, Wehrly K, et al. A 60-kDa prion protein (PrP) with properties of both the normal and scrapie-associated forms of PrP. J Biol Chem 1995;270: 3299-3305.
-
(1995)
J Biol Chem
, vol.270
, pp. 3299-3305
-
-
Priola, S.A.1
Caughey, B.2
Wehrly, K.3
-
74
-
-
0027086835
-
Chimeric prion protein expression in cultured cells and transgenic mice
-
Scott MR, Köhler R, Foster D, et al. Chimeric prion protein expression in cultured cells and transgenic mice. Protein Sci 1992;1:986-97.
-
(1992)
Protein Sci
, vol.1
, pp. 986-997
-
-
Scott, M.R.1
Köhler, R.2
Foster, D.3
-
75
-
-
0028102794
-
Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein
-
Telling GC, Scott M, Hsiao KK, et al. Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein. Proc Natl Acad Sci USA 1994;91:9936-40.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9936-9940
-
-
Telling, G.C.1
Scott, M.2
Hsiao, K.K.3
-
76
-
-
0028822204
-
A single hamster PrP amino acid blocks conversion to protease-resistant PrP in scrapie-infected mouse neuroblastoma cells
-
Priola SA, Chesebro B. A single hamster PrP amino acid blocks conversion to protease-resistant PrP in scrapie-infected mouse neuroblastoma cells. J Virol 1995;69:7754-8.
-
(1995)
J Virol
, vol.69
, pp. 7754-7758
-
-
Priola, S.A.1
Chesebro, B.2
-
77
-
-
0032877492
-
Predicting conformational switches in proteins
-
Young M, Kirshenbaum K, Dill KA, et al. Predicting conformational switches in proteins. Protein Sci 1999;8:1752-64.
-
(1999)
Protein Sci
, vol.8
, pp. 1752-1764
-
-
Young, M.1
Kirshenbaum, K.2
Dill, K.A.3
-
78
-
-
0026496257
-
Fatal familial insomnia and familial Creutzfeldt-Jakob disease: Disease phenotype determined by a DNA polymorphism
-
Goldfarb LG, Petersen RB, Tabaton M, et al. Fatal familial insomnia and familial Creutzfeldt-Jakob disease: disease phenotype determined by a DNA polymorphism. Science 1992;258:806-8.
-
(1992)
Science
, vol.258
, pp. 806-808
-
-
Goldfarb, L.G.1
Petersen, R.B.2
Tabaton, M.3
-
79
-
-
0025859996
-
Genetic predisposition to iatrogenic Creutzfeldt-Jakob disease
-
Collinge J, Palmer MS, Dryden AJ. Genetic predisposition to iatrogenic Creutzfeldt-Jakob disease. Lancet 1991;337:1441-2.
-
(1991)
Lancet
, vol.337
, pp. 1441-1442
-
-
Collinge, J.1
Palmer, M.S.2
Dryden, A.J.3
-
80
-
-
0025820942
-
Homozygous prion protein genotype predisposes to sporadic Creutzfeldt-Jakob disease
-
Palmer MS, Dryden AJ, Hughes JT, et al. Homozygous prion protein genotype predisposes to sporadic Creutzfeldt-Jakob disease. Nature 1991;352:340-2.
-
(1991)
Nature
, vol.352
, pp. 340-342
-
-
Palmer, M.S.1
Dryden, A.J.2
Hughes, J.T.3
-
81
-
-
0029920141
-
Prion protein gene analysis in new variant cases of Creutzfeldt-Jakob disease
-
Collinge J, Beck J, Campbell T, et al. Prion protein gene analysis in new variant cases of Creutzfeldt-Jakob disease. Lancet 1996;348:56.
-
(1996)
Lancet
, vol.348
, pp. 56
-
-
Collinge, J.1
Beck, J.2
Campbell, T.3
-
82
-
-
0028928171
-
Identification of five allelic variants of the sheep PrP gene and their association with natural scrapie
-
Belt PB, Muileman IH, Schreuder BE, et al. Identification of five allelic variants of the sheep PrP gene and their association with natural scrapie. J Gen Virol 1995;76: 509-17.
-
(1995)
J Gen Virol
, vol.76
, pp. 509-517
-
-
Belt, P.B.1
Muileman, I.H.2
Schreuder, B.E.3
-
84
-
-
0029860882
-
PrP genotype contributes to determining survival times of sheep with natural scrapie
-
Bossers A, Schreuder BE, Muileman IH, et al. PrP genotype contributes to determining survival times of sheep with natural scrapie. J Gen Virol 1996;77:2669-73.
-
(1996)
J Gen Virol
, vol.77
, pp. 2669-2673
-
-
Bossers, A.1
Schreuder, B.E.2
Muileman, I.H.3
-
85
-
-
0026001588
-
Different scrapie-associated fibril proteins (PrP) are encoded by lines of sheep selected for different alleles of the Sip gene
-
Goldmann W, Hunter N, Benson G, et al. Different scrapie-associated fibril proteins (PrP) are encoded by lines of sheep selected for different alleles of the Sip gene. J Gen Virol 1991;72:2411-7.
-
(1991)
J Gen Virol
, vol.72
, pp. 2411-2417
-
-
Goldmann, W.1
Hunter, N.2
Benson, G.3
-
86
-
-
0025273876
-
Two alleles of a neural protein gene linked to scrapie in sheep
-
Goldmann W, Hunter N, Foster JD, et al. Two alleles of a neural protein gene linked to scrapie in sheep. Proc Natl Acad Sci USA 1990;87:2476-80.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 2476-2480
-
-
Goldmann, W.1
Hunter, N.2
Foster, J.D.3
-
87
-
-
0029692399
-
Natural scrapie in a closed flock of Cheviot sheep occurs only in specific PrP genotypes
-
Hunter N, Foster JD, Goldmann W, et al. Natural scrapie in a closed flock of Cheviot sheep occurs only in specific PrP genotypes. Arch Virol 1996;141:809-24.
-
(1996)
Arch Virol
, vol.141
, pp. 809-824
-
-
Hunter, N.1
Foster, J.D.2
Goldmann, W.3
-
88
-
-
0027478355
-
PrP polymorphisms associated with natural scrapie discovered by denaturing gradient gel electrophoresis
-
Laplanche JL, Chatelain J, Westaway D, et al. PrP polymorphisms associated with natural scrapie discovered by denaturing gradient gel electrophoresis. Genomics 1993;15:30-7.
-
(1993)
Genomics
, vol.15
, pp. 30-37
-
-
Laplanche, J.L.1
Chatelain, J.2
Westaway, D.3
-
89
-
-
0029161777
-
Different allelic effects of the codons 136 and 171 of the prion protein gene in sheep with natural scrapie
-
Clouscard C, Beaudry P, Elsen JM, et al. Different allelic effects of the codons 136 and 171 of the prion protein gene in sheep with natural scrapie. J Gen Virol 1995;76: 2097-2101.
-
(1995)
J Gen Virol
, vol.76
, pp. 2097-2101
-
-
Clouscard, C.1
Beaudry, P.2
Elsen, J.M.3
-
90
-
-
0028010396
-
The association of a codon 136 PrP gene variant with the occurrence of natural scrapie
-
Hunter N, Goldmann W, Smith G, et al. The association of a codon 136 PrP gene variant with the occurrence of natural scrapie. Arch Virol 1994;137:171-7.
-
(1994)
Arch Virol
, vol.137
, pp. 171-177
-
-
Hunter, N.1
Goldmann, W.2
Smith, G.3
-
91
-
-
0028267507
-
Homozygosity for prion protein alleles encoding glutamine-171 renders sheep susceptible to natural scrapie
-
Westaway D, Zuliani V, Cooper CM, et al. Homozygosity for prion protein alleles encoding glutamine-171 renders sheep susceptible to natural scrapie. Genes Dev 1994; 8:959-69.
-
(1994)
Genes Dev
, vol.8
, pp. 959-969
-
-
Westaway, D.1
Zuliani, V.2
Cooper, C.M.3
-
92
-
-
0036387276
-
Amyloidogenic unfolding intermediates differentiate sheep prion protein variants
-
Rezaei H, Choiset Y, Eghiaian F, et al. Amyloidogenic unfolding intermediates differentiate sheep prion protein variants. J Mol Biol 2002;322:799.
-
(2002)
J Mol Biol
, vol.322
, pp. 799
-
-
Rezaei, H.1
Choiset, Y.2
Eghiaian, F.3
-
93
-
-
0034650634
-
Reversion of prion protein conformational changes by synthetic beta-sheet breaker peptides
-
Soto C, Kascsak RJ, Saborio GP, et al. Reversion of prion protein conformational changes by synthetic beta-sheet breaker peptides. Lancet 2000;355:192-7.
-
(2000)
Lancet
, vol.355
, pp. 192-197
-
-
Soto, C.1
Kascsak, R.J.2
Saborio, G.P.3
-
94
-
-
0035805643
-
Inhibition of interactions and interconversions of prion protein isoforms by peptide fragments from the C-terminal folded domain
-
Horiuchi M, Baron GS, Xiong LW, et al. Inhibition of interactions and interconversions of prion protein isoforms by peptide fragments from the C-terminal folded domain. J Biol Chem 2001;276:15489-97.
-
(2001)
J Biol Chem
, vol.276
, pp. 15489-15497
-
-
Horiuchi, M.1
Baron, G.S.2
Xiong, L.W.3
-
95
-
-
0026510098
-
Sulphate polyanions prolong the incubation period of scrapie-infected hamsters
-
Ladogana A, Casaccia P, Ingrosso L, et al. Sulphate polyanions prolong the incubation period of scrapie-infected hamsters. J Gen Virol 1992;73(Pt 3):661-5.
-
(1992)
J Gen Virol
, vol.73
, Issue.PART 3
, pp. 661-665
-
-
Ladogana, A.1
Casaccia, P.2
Ingrosso, L.3
-
96
-
-
0035108195
-
Branched polyamines cure prion-infected neuroblastoma cells
-
Supattapone S, Wille H, Uyechi L, et al. Branched polyamines cure prion-infected neuroblastoma cells. J Virol 2001;75:3453-61.
-
(2001)
J Virol
, vol.75
, pp. 3453-3461
-
-
Supattapone, S.1
Wille, H.2
Uyechi, L.3
-
97
-
-
0034711993
-
Porphyrin and phthalocyanine antiscrapie compounds
-
Priola SA, Raines A, Caughey WS. Porphyrin and phthalocyanine antiscrapie compounds. Science 2000;287:1503-6.
-
(2000)
Science
, vol.287
, pp. 1503-1506
-
-
Priola, S.A.1
Raines, A.2
Caughey, W.S.3
-
98
-
-
0034001444
-
Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation
-
Doh-Ura K, Iwaki T, Caughey B. Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation. J Virol 2000;74: 4894-7.
-
(2000)
J Virol
, vol.74
, pp. 4894-4897
-
-
Doh-Ura, K.1
Iwaki, T.2
Caughey, B.3
-
99
-
-
0035932993
-
Identification of multiple quantitative trait loci linked to prion disease incubation period in mice
-
Lloyd SE, Onwuazor ON, Beck JA, et al. Identification of multiple quantitative trait loci linked to prion disease incubation period in mice. Proc Natl Acad Sci USA 2001; 98:6279-83.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6279-6283
-
-
Lloyd, S.E.1
Onwuazor, O.N.2
Beck, J.A.3
-
100
-
-
85031192686
-
Post exposure prophylaxis against prion disease in mice using a stimulator of innate immunity
-
Edinburgh, September
-
Kretzschmar HA, Sethi S, Lipford G, Wagner H. Post exposure prophylaxis against prion disease in mice using a stimulator of innate immunity. Plenary presentation at the International Conference of Transmissible Spongiform Encephalopathies, Edinburgh, September 2002.
-
(2002)
International Conference of Transmissible Spongiform Encephalopathies
-
-
Kretzschmar, H.A.1
Sethi, S.2
Lipford, G.3
Wagner, H.4
|