Properties of ethylmethane sulfonate-induced mutations affecting life-history traits in Caenorhabditis elegans and inferences about bivariate distributions of mutation effects

Genetics

Volumn 156, Issue 1, 2000, Pages 143-154

  Keightley, P D ^a   Davies, E K ^a   Peters, A D ^a   Shaw, R G ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MESYLIC ACID ETHYL ESTER;

ARTICLE; CAENORHABDITIS ELEGANS; GENE MUTATION; GENETIC LINKAGE; LIFE CYCLE; LONGEVITY; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; REPRODUCTION;

ANIMALS; CAENORHABDITIS ELEGANS; ETHYL METHANESULFONATE; GENES, HELMINTH; LONGEVITY; MUTAGENS; MUTATION; REPRODUCTION;

CAENORHABDITIS ELEGANS; INVERTEBRATA;

EID: 0033832535     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Mutagenesis
2. Pleiotropic models of quantitative variation
3. The viability of near-normal irradiated chromosomes
4. Evolutionary mechanisms of senescence
5. Some evolutionary consequences of deleterious mutations
6. Ageing: Levelling of the grim reaper
7. High frequency of cryptic deleterious mutations in Caenorhabditis elegans
8. Evolution of senescence and specific longevity
9. Spontaneous mutational variances and covariances for fitness-related traits in Drosophila melanogaster
10. Properties of spontaneous mutations affecting quantitative traits
11. Average information REML, an efficient algorithm for variance parameter estimation in linear mixed models
12. The molding of senescence by natural selection
13. Inference of moments of effects of individual inserts
14. The effects of spontaneous mutation on quantitative traits. I. Variances and covariances of life history traits
15. A genetic analysis of senescence in Drosophila
16. Absence of strong heterosis for life span and other life history traits in Caenorhabditis elegans
17. Inference of genome wide mutation rates and distributions of mutation effects for fitness traits: A simulation study
18. Multi-generation maximum likelihood analysis applied to mutation accumulation experiments in Caenorhabditis elegans
19. Genomic mutation rates for lifetime reproductive output and lifespan in Caenorhabditis elegans
20. Terumi Mukai and the riddle of deleterious mutation rates
21. Variation maintained in quantitative traits with mutation-selection balance: Pleiotropic side-effects on fitness traits
22. EMS induced polygenic mutation rates for nine quantitative characters in Drosophila melanogaster
23. Environmental factors and gene activities that influence lifespan
24. Perspective: Spontaneous deleterious mutation
25. Effects of P element insertions on quantitative traits in Drosophila melanogaster
26. Old age and natural death
27. The genetic structure of natural populations of Drosophila melanogaster. I. Spontaneous mutation rate of polygenes controlling viability
28. Mutation rate and dominance of genes affecting viability in Drosophila melanogaster
29. A simplex method for function minimization
30. Sex-specific quantitative trait loci affecting longevity in Drosophila melanogaster
31. Spontaneous and ethyl methanesulfonate induced mutations controlling viability in Drosophila melanogaster. II. Homozygous effect of polygenic mutations
32. Optimality, mutation and the evolution of ageing
33. The evolution of age-specific mortality rates in Drosophila melanogaster: Genetic divergence among unselected lines
34. Age-specific patterns of genetic variance in Drosophila melanogaster. I. Mortality
35. The nature of quantitative genetic variation
36. Antagonistic pleiotropy, dominance, and genetic variation
37. Bivariate gamma random vectors
38. Pattern of selective constraint in C. elegans and C. briggsae genomes
39. Mapping quantitative trait loci affecting life history traits in the nematode Caenorhabditis elegans
40. Codon usage in Caenorhabditis elegans - Delineation of translational selection and mutational biases
41. The rate of spontaneous mutation for life-history traits in Caenorhabditis elegans
42. The impact of heterogeneity in individual frailty on the dynamics of mortality
43. Pleitropy, natural selection and the evolution of senescence
44. Natural selection, the costs of reproduction, and a refinement of Lack's principle
45. The evolution genetics of ageing and longevity