Combined treatment with specific ligands for PPARγ:RXR nuclear receptor system markedly inhibits the expression of cytochrome P450arom in human granulosa cancer cells

Molecular and Cellular Endocrinology

Volumn 181, Issue 1-2, 2001, Pages 239-248

  Mu, Yi Ming ^a   Yanase, Toshihiko ^a,b   Nishi, Yoshihiro ^a   Takayanagi, Ryoichi ^a,b   Goto, Kiminobu ^a,b   Nawata, Hajime ^a,b  

^a KYUSHU UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Aromatase; Granulosa cancer cell; Peroxisome proliferator activated receptor gamma; Retinoid X receptor; Troglitazone

Indexed keywords

6 [1 (5,6,7,8 TETRAHYDRO 3,5,5,8,8 PENTAMETHYL 2 NAPHTHYL)CYCLOPROPYL]NICOTINIC ACID; AROMATASE; CELL NUCLEUS RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; ENZYME; FORSKOLIN; LIGAND; LUCIFERASE; MESSENGER RNA; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROSTAGLANDIN E2; RETINOID X RECEPTOR; RIBONUCLEASE; TROGLITAZONE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; ASSAY; CANCER CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GRANULOSA CELL TUMOR; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RNA DEGRADATION; RNA STABILITY;

AROMATASE; CELL DIVISION; CHROMANS; DACTINOMYCIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME INDUCTION; ESTRONE; FEMALE; GRANULOSA CELL TUMOR; HUMANS; LIGANDS; NICOTINIC ACIDS; OVARY; PROMOTER REGIONS (GENETICS); RADIOIMMUNOASSAY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, FSH; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; RNA, MESSENGER; TETRAHYDRONAPHTHALENES; THIAZOLES; THIAZOLIDINEDIONES; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0035811516     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(00)00457-3     Document Type: Article

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