Modulation of AMPA receptors by cAMP-dependent protein kinase in preBötzinger complex inspiratory neurons regulates respiratory rhythm in the rat

Journal of Physiology

Volumn 547, Issue 2, 2003, Pages 543-553

  Shao, Xuesi M ^a   Ge, Qing ^a,b   Feldman, Jack L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF TENNESSEE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; ADENOSINE 3',5' PHOSPHOROTHIOATE; ADENYLATE CYCLASE ACTIVATOR; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; AMPA RECEPTOR ANTAGONIST; CYCLIC AMP DEPENDENT PROTEIN KINASE; DIZOCILPINE; EXCITATORY AMINO ACID; FORSKOLIN; FORSKOLIN DERIVATIVE; ISOBUTYLMETHYLXANTHINE; KAINIC ACID RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PHOSPHODIESTERASE INHIBITOR; PROTEIN KINASE INHIBITOR; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; TETRODOTOXIN;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; BRAIN SLICE; BREATHING RATE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; EXCITATORY POSTSYNAPTIC POTENTIAL; EXPIRATORY FLOW; FREQUENCY ANALYSIS; FREQUENCY MODULATION; HYPOGLOSSAL NERVE; HYPOTHESIS; INHIBITORY POSTSYNAPTIC POTENTIAL; INTRACELLULAR MEMBRANE; LUNG VENTILATION; MEDULLA OBLONGATA; MICROINJECTION; NERVE CELL EXCITABILITY; NERVE CELL MEMBRANE POTENTIAL; NERVE CELL MEMBRANE STEADY POTENTIAL; NEUROMODULATION; NEWBORN; NONHUMAN; POSTSYNAPTIC INHIBITION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; RESPIRATION CONTROL; RESPIRATORY FUNCTION; RESPIRATORY NERVE CELL; REVIEW; SLOW INWARD CURRENT; SYNAPTIC TRANSMISSION; VOLTAGE CLAMP; AMPLITUDE MODULATION; ARTICLE; BREATHING; ELECTROPHYSIOLOGY; NERVE CELL; PREBOTZINGER COMPLEX INSPIRATORY NEURON; RESPIRATORY RHYTHM; VOLTAGE CLAMP TECHNIQUE;

ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ELECTRIC CONDUCTIVITY; EXCITATORY POSTSYNAPTIC POTENTIALS; INHALATION; MEDULLA OBLONGATA; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; RESPIRATORY MECHANICS;

EID: 0037335751     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2002.031005     Document Type: Review

References (42)

1. Badie-Mahdavi H, Worsley MA, Ackley MA, Asghar AU, Slack JR & King AE (2001). A role for protein kinase intracellular messengers in substance P- and nociceptor afferent-mediated excitation and expression of the transcription factor Fos in rat dorsal horn neurons in vitro. Eur J Neurosci 14, 426-434.
2. Banke TG, Bowie D, Lee H, Huganir RL, Schousboe A & Traynelis SF (2000). Control of GluR1 AMPA receptor function by cAMP-dependent protein kinase. J Neurosci 20, 89-102.
3. Blackstone C, Murphy TH, Moss SJ, Baraban JM & Huganir RL (1994). Cyclic AMP and synaptic activity-dependent phosphorylation of AMPA-preferring glutamate receptors. J Neurosci 14, 7585-7593.
4. Browning KN & Travagli RA (2001). The peptide TRH uncovers the presence of presynaptic 5-HT1A receptors via activation of a second messenger pathway in the rat dorsal vagal complex. J Physiol 531, 425-435.
5. Butera R, Rinzel J & Smith J (1999). Models of respiratory rhythm generation in the pre-Bötzinger complex. II. Populations of coupled pacemaker neurons. J Neurophysiol 82, 398-451.
6. Cai X, Flores-Hernandez J, Feng J & Yan Z (2002). Activity-dependent bidirectional regulation of GABA(A) receptor channels by the 5-HT(4) receptor-mediated signalling in rat prefrontal cortical pyramidal neurons. J Physiol 540, 743-759.
7. Chavez-Noriega LE & Stevens CF (1994). Increased transmitter release at excitatory synapses produced by direct activation of adenylate cyclase in rat hippocampal slices. J Neurosci 14, 310-317.
8. Colwell CS & Levine MS (1995). Excitatory synaptic transmission in neostriatal neurons: regulation by cyclic AMP-dependent mechanisms. J Neurosci 15, 1704-1713.
9. B receptors. In The GABA Receptors, ed. Enna SJ & Bowery NG, pp. 157-207. Humana, Totowa, New Jersey.
10. Evans DI, Jones RS & Woodhall G (2001). Differential actions of PKA and PKC in the regulation of glutamate release by group III mGluRs in the entorhinal cortex. J Neurophysiol 85, 571-579.
11. Felder CC (1995). Muscarinic acetylcholine receptors: signal transduction through multiple effectors. FASEB J 9, 619-625.
12. Funk GD, Johnson SM, Smith JC, Dong XW, Lai J & Feldman JL (1997). Functional respiratory rhythm generating networks in neonatal mice lacking NMDAR1 gene. J Neurophysiol 78, 1414-1420.
13. Funk GD, Smith JC & Feldman JL (1993). Generation and transmission of respiratory oscillations in medullary slices: role of excitatory amino acids. J Neurophysiol 70, 1497-1515.
14. Ge Q & Feldman JL (1998). AMPA receptor activation and phosphatase inhibition affect neonatal rat respiratory rhythm generation. J Physiol 509, 255-266.
15. Glass DB, Cheng HC, Mende-Mueller L, Reed J & Walsh DA (1989). Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein. J Biol Chem 264, 8802-8810.
16. Gray PA, Relding JC, Bocchiaro CM & Feldman JL (1999). Modulation of respiratory frequency by peptidergic input to rhythmogenic neurons in the preBötzinger complex. Science 286, 1566-1568.
17. Greengard P, Jen J, Nairn AC & Stevens CF (1991). Enhancement of the glutamate response by cAMP-dependent protein kinase in hippocampal neurons. Science 253, 1135-1138.
18. Johnson SM, Smith JC & Feldman JL (1996). Modulation of respiratory rhythm in vitro: role of Gi/o protein-mediated mechanisms. J Appl Physiol 80, 2120-2133.
19. Kameyama K, Lee HK, Bear MF & Huganir RL (1998). Involvement of a postsynaptic protein kinase A substrate in the expression of homosynaptic long-term depression. Neuron 21, 1163-1175.
20. Khawaja AM & Rogers DF (1996). Tachykinins: receptor to effector. Int J Biochem Cell Biol 28, 721-738.
21. Koshiya N & Smith JC (1999). Neuronal pacemaker for breathing visualized in vitro. Nature 400, 360-363.
22. Lee HK, Barbarosie M, Kameyama K, Bear MF & Huganir RL (2000). Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity. Nature 405, 955-959.
23. Lukyanetz EA & Kostyuk PG (1996). Two distinct receptors operate the cAMP cascade to up-regulate L-type Ca channels. Pflugers Arch 432, 174-181.
24. Murakoshi T, Suzue T & Tamai S (1985). A pharmacological study on respiratory rhythm in the isolated brainstem-spinal cord preparation of the newborn rat. Br J Pharmacol 86, 95-104.
25. Nestler EJ (1997). Molecular mechanisms of opiate and cocaine addiction. Curr Opin Neurobiol 7, 713-719.
26. Neter J, Wasserman W & Kutner MH (ed.) (1990). Repeated measures and related designs. In Applied Linear Statistical Models, pp. 1035-1073. Irwin, Homewood, IL.
27. Nijholt I, Blank T, Liu A, Kügler H & Spiess J (2000). Modulation of hypothalamic NMDA receptor function by cyclic AMP-dependent protein kinase and phosphatases. J Neurochem 75, 749-754.
28. Oka M, Itoh Y, Ukai Y, Yoshikuni Y & Kimura K (1996). Protein kinases are involved in prolonged acetylcholine release from rat hippocampus induced by thyrotropin-releasing hormone analogue NS-3. J Neurochem 66, 1889-1893.
29. Rekling JC, Champagnat J & Denavit-Saubié M (1996). Thyrotropin-releasing hormone (TRH) depolarizes a subset of inspiratory neurons in the newborn mouse brain stem in vitro. J Neurophysiol 75, 811-819.
30. Rekling JC & Feldman JL (1998). PreBötzinger complex and pacemaker neurons: hypothesized site and kernel for respiratory rhythm generation. Annu Rev Physiol 60, 385-405.
31. Rekling JC, Shao XM & Feldman JL (2000). Electrical coupling and excitatory synaptic transmission between rhythmogenic respiratory neurons in the preBötzinger complex. J Neurosci 20, RC113.
32. Roche KW, O'Brien RJ, Mammen AL, Bernhardt J & Huganir RL (1996). Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit. Neuron 16, 1179-1188.
33. Shao XM & Feldman JL (2000). Acetylcholine modulates respiratory pattern: effects mediated by M3-like receptors in preBötzinger complex inspiratory neurons. J Neurophysiol 83, 1243-1252.
34. Shao XM & Feldman JL (2001). Mechanisms underlying regulation of respiratory pattern by nicotine in preBötzinger Complex. J Neurophysiol 85, 2461-2467.
35. Smith JC, Ellenberger HH, Ballanyi K, Richter DW & Feldman JL (1991). Pre-Bötzinger complex: a brainstem region that may generate respiratory rhythm in mammals. Science 254, 726-729.
36. Smith JC, Greer JJ, Liu GS & Feldman JL (1990). Neural mechanisms generating respiratory pattern in mammalian brain stem-spinal cord in vitro. I. Spatiotemporal patterns of motor and medullary neuron activity. J Neurophysiol 64, 1149-1169.
37. Snyder GL, Fienberg AA, Huganir RL & Greengard P (1998). A dopamine/D1 receptor/protein kinase A/dopamine- and cAMP-regulated phosphoprotein (Mr 32 kDa)/protein phosphatase-1 pathway regulates dephosphorylation of the NMDA receptor. J Neurosci 18, 10297-10303.
38. Soderling TR & Derkach VA (2000). Postsynaptic protein phosphorylation and LTP. Trends Neurosci 23, 75-80.
39. Traynelis SF & Wahl P (1997). Control of rat GluR6 glutamate receptor open probability by protein kinase A and calcineurin. J Physiol 503, 513-531.
40. Wang LY, Salter MW & MacDonald JF (1991). Regulation of kainate receptors by cAMP-dependent protein kinase and phosphatases. Science 253, 1132-1135.
41. Wang LY, Taverna FA, Huang XP, MacDonald JF & Hampson DR (1993). Phosphorylation and modulation of a kainate receptor (GluR6) by cAMP-dependent protein kinase. Science 259, 1173-1175.
42. Wojcik WJ & Neff NH (1984). gamma-aminobutyric acid B receptors are negatively coupled to adenylate cyclase in brain, and in the cerebellum these receptors may be associated with granule cells. Mol Pharmacol 25, 24-28.