Aspartate-107 and leucine-109 facilitate efficient coupling of glutamine hydrolysis to CTP synthesis by Escherichia coli CTP synthase

Biochemical Journal

Volumn 369, Issue 3, 2003, Pages 497-507

  Iyengar, Akshai ^a   Bearne, Stephen L ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Amidotransferase; Glutaminase; Mutagensis; Tunnel

Indexed keywords

AMINO ACIDS; ENZYMES; ESCHERICHIA COLI; HYDROLYSIS; MUTAGENESIS; NITROGEN;

ALLOSTERIC EFFECTORS;

BIOCHEMISTRY;

AMIDE; AMMONIA; ASPARTIC ACID; CYTIDINE TRIPHOSPHATE; CYTIDINE TRIPHOSPHATE SYNTHASE; ENZYME; GLUTAMINASE; GLUTAMINE; LEUCINE; NITROGEN; UNCLASSIFIED DRUG; URIDINE TRIPHOSPHATE;

AMINO ACID SEQUENCE; ARTICLE; BACTERIUM MUTANT; CATALYSIS; ENZYME ACTIVITY; ENZYME KINETICS; ESCHERICHIA COLI; HYDROLYSIS; NONHUMAN; NUCLEOTIDE BINDING SITE; OLIGOMERIZATION; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; SYNTHESIS; WILD TYPE;

ALANINE; AMINO ACID SEQUENCE; ASPARTIC ACID; CARBON-NITROGEN LIGASES; CIRCULAR DICHROISM; CONSERVED SEQUENCE; CYTIDINE TRIPHOSPHATE; DIMERIZATION; ESCHERICHIA COLI PROTEINS; GLUTAMINE; GUANOSINE TRIPHOSPHATE; HYDROLYSIS; LEUCINE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0037330389     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20021110     Document Type: Article

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