Interaction of the sensor module of Mycobacterium tuberculosis H37Rv KdpD with members of the Lpr family

Molecular Microbiology

Volumn 47, Issue 4, 2003, Pages 1075-1089

  Steyn, Adrie J C ^a   Joseph, Joan ^a   Bloom, Barry R ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; BACTERIAL PROTEIN; LIPOPROTEIN; MEMBRANE PROTEIN; POTASSIUM ION; PROTEIN HISTIDINE KINASE; PROTEIN KDPD; PROTEIN LPRF; PROTEIN LPRJ; UNCLASSIFIED DRUG;

ALLELISM; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL GENE; BACTERIAL MEMBRANE; BACTERIAL VIRULENCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; LIGAND BINDING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OSMOTIC STRESS; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SENSOR; SIGNAL TRANSDUCTION;

ALLELES; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BASE SEQUENCE; GENE EXPRESSION; GENES, BACTERIAL; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; PLASMIDS; POTASSIUM; PROTEIN KINASES; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); MYCOBACTERIUM; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; UNCULTURED ACTINOMYCETE;

EID: 0037329291     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2003.03356.x     Document Type: Article

References (59)

1. Alberts, B., Bray, D., Lewis, J., Raff, M., Roberts, K., and Watson, J. (1989) Molecular Biology of the Cell. New York: Garland Publishing.
2. Alland, D., Steyn, A.J., Weisbrod, T., Aldrich, K., and Jacobs, W.R., Jr (2000) Characterization of the Mycobacterium tuberculosis iniBAC promoter, a promoter that responds to cell wall biosynthesis inhibition. J Bacteriol 182: 1802-1811.
3. Altendorf, K., Voelkner, P., and Puppe, W. (1994) The sensor kinase KdpD and the response regulator KdpE control expression of the kdpFABC operon in Escherichia coli. Res Microbiol 145: 374-381.
4. Ashbridge, K.R., Booth, R.J., Watson, J.D., and Lathigra, R.B. (1989) Nucleotide sequence of the 19 kDa antigen gene from Mycobacterium tuberculosis. Nucleic Acids Res 17: 1249.
5. Behr, M.A., Wilson, M.A., Gill, W.P., Salamon, H., Schoolnik, G.K., Rane, S., and Small, P.M. (1999) Comparative genomics of BCG vaccines by whole-genome DNA microarray. Science 284: 1520-1523.
6. Betts, J.C., Lukey, P.T., Robb, L.C., McAdam, R.A., and Duncan, K. (2002) Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling. Mol Microbiol 43: 717-731.
7. Booth, I.R., and Higgins, C.F. (1990) Enteric bacteria and osmotic stress: intracellular potassium glutamate as a secondary signal of osmotic stress? FEMS Microbiol Rev 6: 239-246.
8. Brandon, L., Dorus, S., Epstein, W., Altendorf, K., and Jung, K. (2000) Modulation of KdpD phosphatase implicated in the physiological expression of the kdp ATPase of Escherichia coli. Mol Microbiol 38: 1086-1092.
9. Braunstein, M., Griffin, T.I., Kriakov, J.I., Friedman, S.T., Grindley, N.D., and Jacobs, W.R., Jr (2000) Identification of genes encoding exported Mycobacterium tuberculosis proteins using a Tn552'phoA in vitro transposition system. J Bacteriol 182: 2732-2740.
10. Brosch, R., Gordon, S.V., Eiglmeier, K., Garnier, T., Tekaia, F., Yeramian, E., and Cole, S.T. (2000) Genomics, biology, and evolution of the Mycobacterium tuberculosis complex. In: Molecular Genetics of Mycobacteria. Hatfull, G.F., and Jacobs, W.R. (eds). Washington, DC: American Society for Microbiology Press, pp. 19-36.
11. Cole, S.T. (1999) Learning from the genome sequence of Mycobacterium tuberculosis H37Rv. FEBS Lett 452: 7-10.
12. Cole, S.T., Brosch, R., Parkhill, J., Garnier, T., Churcher, C., Harris, D., Gordon, S.V., et al. (1998) Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393: 537-544.
13. Cotter, P.A., and DiRita, V.J. (2000) Bacterial virulence gene regulation: an evolutionary perspective. Annu Rev Microbiol 54: 519-565.
14. Cox, J.S., Chen, B., McNeil, M., and Jacobs, W.R., Jr (1999) Complex lipid determines tissue-specific replication of Mycobacterium tuberculosis in mice. Nature 402: 79-83.
15. Dartois, V., Djavakhishvili, T., and Hoch, J.A. (1997) KapB is a lipoprotein required for KinB signal transduction and activation of the phosphorelay to sporulation in Bacillus subtilis. Mol Microbiol 26: 1097-1108.
16. Dasgupta, N., Kapur, V., Singh, K.K., Das, T.K., Sachdeva, S., Jyothisri, K., and Tyagi, J.S. (2000) Characterization of a two-component system, devR-devS, of Mycobacterium tuberculosis. Tuber Lung Dis 80: 141-159.
17. + transport in Escherichia coli. Biochem Soc Trans 21: 1006-1010.
18. Ewann, F., Jackson, M., Pethe, K., Cooper, A., Mielcarek, N., Ensergueix, D., et al. (2002) Transient requirement of the PrrA-PrrB two-component system for early intracellular multiplication of Mycobacterium tuberculosis. Infect Immun 70: 2256-2263.
19. Franke, C.M., Tiemersma, J., Venema, G., and Kok, J. (1999) Membrane topology of the lactococcal bacteriocin ATPbinding cassette transporter protein LcnC. Involvement of LcnC in lactococcin a maturation. J Biol Chem 274: 8484-8490.
20. Garnerone, A.M., Cabanes, D., Foussard, M., Boistard, P., and Batut, J. (1999) Inhibition of the FixL sensor kinase by the FixT protein in Sinorhizobium meliloti. J Biol Chem 274: 32500-32506.
21. Glickman, M.S., and Jacobs, W.R., Jr (2001) Microbial pathogenesis of Mycobacterium tuberculosis: dawn of a discipline. Cell 104: 477-485.
22. Gowrishankar, J. (1985) Identification of osmoresponsive genes in Escherichia coli: evidence for participation of potassium and proline transport systems in osmoregulation. J Bacteriol 164: 434-445.
23. Haydel, S.E., Benjamin, W.H., Jr, Dunlap, N.E., and Clark-Curtiss, J.E. (2002) Expression, autoregulation, and DNA binding properties of the Mycobacterium tuberculosis TrcR response regulator. J Bacteriol 184: 2192-2203.
24. Heermann, R., Altendorf, K., and Jung, K. (2000) The hydrophilic N-terminal domain complements the membrane-anchored C-terminal domain of the sensor kinase KdpD of Escherichia coli. J Biol Chem 275: 17080-17085.
25. Himpens, S., Locht, C., and Supply, P. (2000) Molecular characterization of the mycobacterial SenX3-RegX3 two-component system: evidence for autoregulation. Microbiology 146: 3091-3098.
26. Hou, J.Y., Graham, J.E., and Clark-Curtiss, J.E. (2002) Mycobactedum avium genes expressed during growth in human macrophages detected by selective capture of transcribed sequences (SCOTS). Infect Immun 70: 3714-3726.
27. James, P., Halladay, J., and Craig, E.A. (1996) Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics 144: 1425-1436.
28. Jung, K., and Altendorf, K. (1998) Truncation of amino acids 12-128 causes deregulation of the phosphatase activity of the sensor kinase KdpD of Escherichia coli. J Biol Chem 273: 17406-17410.
29. Jungblut, P.R., Schaible, U.E., Mollenkopf, H.J., Zimny-Arndt, U., Raupach, B., Mattow, J., et al. (1999) Comparative proteome analysis of Mycobacterium tuberculosis and Mycobacterium bovis BCG strains: towards functional genomics of microbial pathogens. Mol Microbiol 33: 1103-1117.
30. Malli, R., and Epstein, W. (1998) Expression of the Kdp ATPase is consistent with regulation by turgor pressure. J Bacteriol 180: 5102-5108.
31. Martinez-Argudo, I., Martin-Nieto, J., Salinas, P., Maldonado, R., Drummond, M., and Contreras, A. (2001) Two-hybrid analysis of domain interactions involving NtrB and NtrC two-component regulators. Mol Microbiol 40: 169-178.
32. Paweletz, C.P., Ornstein, D.K., Roth, M.J., Bichsel, V.E., Gillespie, J.W., Calvert, V.S., et al. (2000) Loss of annexin 1 correlates with early onset of tumorigenesis in esophageal and prostate carcinoma. Cancer Res 60: 6293-6297.
33. Perez, E., Samper, S., Bordas, Y., Guilhot, C., Gicquel, B., and Martin, C. (2001) An essential role for phoP in Mycobacterium tuberculosis virulence. Mol Microbiol 41: 179-187.
34. Pioszak, A.A., Jiang, P., and Ninfa, A.J. (2000) The Escherichia coli PII signal transduction protein regulates the activities of the two-component system transmitter protein NRII by direct interaction with the kinase domain of the transmitter module. Biochemistry 39: 13450-13461.
35. Polarek, J.W., Williams, G., and Epstein, W. (1992) The products of the kdpDE operon are required for expression of the Kdp ATPase of Escherichia coli. J Bacteriol 174: 2145-2151.
36. +-translocating Kdp system of Escherichia coli. J Biol Chem 271: 25027-25034.
37. Raivio, T.L., and Silhavy, T.J. (1997) Transduction of envelope stress in Escherichia coli by the Cpx two-component system. J Bacteriol 179: 7724-7733.
38. + flux. Nature 416: 291-297.
39. Sardesai, A.A., and Gowrishankar, J. (2001) trans-acting mutations in loci other than kdpDE that affect kdp operon regulation in Escherichia coli: effects of cytoplasmic thiol oxidation status and nucleoid protein H-NS on kdp expression. J Bacteriol 183: 86-93.
40. Smith, I., Dubnau, J., Manganelli, R., Rodriguez, G., Gold, B., Walters, S., et al. (1999) Identification and Characterization of Potential Virulence Genes of Mycobacterium Tuberculosis. US-Japan Cooperative Medical Science Program, Thirty-Fourth Tuberculosis-Leprosy Research Conference. San Francisco: National Institute of Health, pp. 108-112.
41. Snyder, W.B., Davis, L.J., Danese, P.N., Cosma, C.L., and Silhavy, T.J. (1995) Overproduction of NIpE, a new outer membrane lipoprotein, suppresses the toxicity of periplasmic LacZ by activation of the Cpx signal transduction pathway. J Bacteriol 177: 4216-4223.
42. Stanton, T. (2000) Ecological aspects of host colonization: coaggregation, osmoadaptation, and acid tolerance or resistance. In Virulence Mechanisms of Bacterial Pathogens. Brogden, K.A. (ed.). Washington, DC: American Society for Microbiology Press, pp. 61-75.
43. Steyn, A.J.C., Chan, J., and Mehra, V. (1999) Recent developments in mycobacterial research. Curr Opin Infect Dis 12: 415-424.
44. Steyn, A.J., Collins, D.M., Hondalus, M.K., Jacobs, W.R., Jr, Kawakami, R.P., and Bloom, B.R. (2002) Mycobacterium tuberculosis WhiB3 interacts with RpoV to affect host survival but is dispensable for in vivo growth. Proc Natl Acad Sci USA 99: 3147-3152.
45. Stock, A.M., Robinson, V.L., and Goudreau, P.N. (2000) Two-component signal transduction. Annu Rev Biochem 69: 183-215.
46. Svetlov, V., and Cooper, T.G. (1998) Efficient PCR-based random mutagenesis of sub-genic (100 bp) DNA fragments. Yeast 14: 89-91.
47. Takatsu, H., Futatsumori, M., Yoshino, K., Yoshida, Y., Shin, H.W., and Nakayama, K. (2001) Similar subunit interactions contribute to assembly of clathrin adaptor complexes and COPI complex: analysis using yeast three-hybrid system. Biochem Biophys Res Commun 284: 1083-1089.
48. Tam, R., and Saier, M.H., Jr (1993) Structural, functional, and evolutionary relationships among extracellular solute-binding receptors of bacteria. Microbiol Rev 57: 320-346.
49. Thoma-Uszynski, S., Stenger, S., Takeuchi, O., Ochoa, M.T., Engele, M., Sieling, P.A., et al. (2001) Induction of direct antimicrobial activity through mammalian toll-like receptors. Science 291: 1544-1547.
50. Tirode, F., Malaguti, C., Romero, F., Attar, R., Camonis, J., and Egly, J.M. (1997) A conditionally expressed third partner stabilizes or prevents the formation of a transcriptional activator in a three-hybrid system. J Biol Chem 272: 22995-22999.
51. Triccas, J.A., Berthet, F.X., Pelicic, V., and Gicquel, B. (1999) Use of fluorescence induction and sucrose counterselection to identify Mycobacterium tuberculosis genes expressed within host cells. Microbiology 145: 2923-2930.
52. Vuillard, L., Rabilloud, T., and Goldberg, M.E. (1998) Interactions of non-detergent sulfobetaines with early folding intermediates facilitate in vitro protein renaturation. Eur J Biochem 256: 128-135.
53. Walderhaug, M.O., Polarek, J.W., Voelkner, P., Daniel, J.M., Hesse, J.E., Altendorf, K., and Epstein, W. (1992) KdpD and KdpE, proteins that control expression of the kdpABC operon, are members of the two-component sensor-effector class of regulators. J Bacteriol 174: 2152-2159.
54. Wheeler, P., and Ratledge, C. (1994) Metabolism of Mycobacterium tuberculosis. In Tuberculosis, Pathogenesis, Protection and Control. Bloom, B.R. (ed.). Washington, DC: American Society for Microbiology Press, pp. 353-385.
55. Wiker, H.G., Wilson, M.A., and Schoolnik, G.K. (2000) Extracytoplasmic proteins of Mycobacterium tuberculosis - mature secreted proteins often start with aspartic acid and proline. Microbiology 146: 1525-1533.
56. Wright, J.S., Olekhnovich, I.N., Touchie, G., and Kadner, R.J. (2000) The histidine kinase domain of UhpB inhibits UhpA action at the Escherichia coli uhpT promoter. J Bacteriol 182: 6279-6286.
57. Zahrt, T.C., and Deretic, V. (2000) An essential two-component signal transduction system in Mycobacterium tuberculosis. J Bacteriol 182: 3832-3838.
58. Zahrt, T.C., and Deretic, V. (2001) Mycobacterium tuberculosis signal transduction system required for persistent infections. Proc Natl Acad Sci USA 98: 12706-12711.
59. Zimmann, P., Puppe, W., and Altendorf, K. (1995) Membrane topology analysis of the sensor kinase KdpD of Escherichia coli. J Biol Chem 270: 28282-28288.