Transduction of envelope stress in Escherichia coli by the Cpx two- component system

Journal of Bacteriology

Volumn 179, Issue 24, 1997, Pages 7724-7733

  Raivio, Tracy L ^a   Silhavy, Thomas J ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTIDINE; HYBRID PROTEIN; MALTOSE BINDING PROTEIN; MEMBRANE PROTEIN; PHOSPHATASE; PHOSPHOTRANSFERASE;

ARTICLE; BACTERIAL MEMBRANE; CONTROLLED STUDY; CYTOPLASM; ESCHERICHIA COLI; GENE EXPRESSION; GENE LOCUS; GENE MUTATION; MEMBRANE TRANSPORT; NONHUMAN; PHOSPHATE TRANSPORT; PRIORITY JOURNAL; PROTEIN TRANSPORT; REGULATOR GENE; SIGNAL TRANSDUCTION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0030834844     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.179.24.7724-7733.1997     Document Type: Article

References (76)

1. Aiba, H., F. Nakasai, S. Mizushima, and T. Mizuno. 1989. Phosphorylation of a bacterial activator protein, OmpR, by a protein kinase, EnvZ, results in stimulation of its DNA-binding ability. J. Biochem. 106:5-8.
2. Aiba, H., F. Nakasai, S. Mizushima, and T. Mizuno. 1989. Evidence for the physiological importance of the phosphotransfer between the two regulatory components, EnvZ and OmpR, in osmoregulation in Escherichia coli. J. Biol. Chem. 264:14090-14094.
3. Akiyama, Y., S. Kamitani, N. Kusukawa, and K. Ito. 1992. In vitro catalysis of oxidative folding of disulfide-bonded proteins by the Escherichia coli dsbA (ppfA) gene product. J. Biol. Chem. 267:22440-22445.
4. Bardwell, J. C., J. O. Lee, G. Jander, N. Martin, D. Belin, and J. Beckwith. 1993. A pathway for disulfide bond formation in vivo. Proc. Natl. Acad. Sci. USA 90:1038-1042.
5. Bardwell, J. C., K. McGovern, and J. Beckwith. 1991. Identification of a protein required for disulfide bond formation in vivo. Cell 67:581-589.
6. Casadaban, M. J. 1976. Transposition and fusion of lac genes to selected promoters in Escherichia coli using bacteriophages lambda and Mu. J. Mol. Biol. 104:541-555.
7. Cavicchioli, R., R. C. Chiang, L. V. Kalman, and R. P. Gunsalus. 1996. Role of the periplasmic domain of the Escherichia coli NarX sensor-transmitter protein in nitrate-dependent signal transduction and gene regulation. Mol. Microbiol. 21:901-911.
8. Chervitz, S. A., and J. J. Falke. 1996. Molecular mechanism of transmembrane signaling by the aspartate receptor: a model. Proc. Natl. Acad. Sci. USA 93:2245-2250.
9. Chervitz, S. A., and J. J. Falke. 1995. Lock on/off disulfides identify the transmembrane signaling helix of the aspartate receptor. J. Biol. Chem. 270:24043-24053.
10. Collins, L. A., S. M. Egan, and V. Stewart. 1992. Mutational analysis reveals functional similarity between NARX, a nitrate sensor in Escherichia coli K-12, and the methyl-accepting chemotaxis proteins. J. Bacteriol. 174:3667-3675.
11. Connelly, L., A. De Las Penas, B. M. Alba, and C. A. Gross. The response to extracytoplasmic stress in Escherichia coli is controlled by partially overlapping pathways. Genes Dev., in press.
12. Cosma, C. L., P. N. Danese, J. H. Carlson, T. J. Silhavy, and W. B. Snyder. 1995. Activation of the Cpx two-component signal transduction pathway in Escherichia coli suppresses envelope associated stresses. Mol. Microbiol. 18:491-505.
13. Cox, J. S., C. E. Shamu, and P. Walter. 1993. Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase. Cell 73:1197-1206.
14. Danese, P. N. 1996. Ph.D. thesis. Princeton University, Princeton, N.J.
15. E and the Cpx signal transduction systems control the synthesis of periplasmic protein-folding enzymes in Escherichia coli. Genes Dev. 11:1183-1193.
16. 15a.Danese, P. N., and T. J. Silhavy. Unpublished data.
17. Danese, P. N., W. B. Snyder, C. L. Cosma, L. J. Davis, and T. J. Silhavy. 1995. The Cpx two-component signal transduction pathway of Escherichia coli regulates transcription of the gene specifying the stress-inducible periplasmic protease, DegP. Genes Dev. 9:387-398.
18. E. Mol. Microbiol. 24:373-385.
19. Dong, J. S., S. Iuchi, H. S. Kwan, Z. Lu, and E. C. C. Lin. 1993. The deduced amino-acid sequence of the cloned cpxR gene suggests the protein is the cognate regulator for the membrane sensor, CpxA, in a two-component signal transduction system of Escherichia coli. Gene 136:227-230.
20. E subunit of Escherichia coli RNA polymerase: a second alternate σ factor involved in high-temperature gene expression. Genes Dev. 3:1462-1471.
21. Hoch, J. A., and T. J. Silhavy (ed.). 1995. Two-component signal transduction. ASM Press, Washington, D.C.
22. Horne, S. M., and K. D. Young. 1995. Escherichia coli and other species of the Enterobacteriaceae encode a protein similar to the family of Mip-like FK506-binding proteins. Arch. Microbiol. 163:357-365.
23. Huang, K. J., C. Y. Lan, and M. M. Igo. 1997. Phosphorylation stimulates the cooperative DNA-binding properties of the transcription factor OmpR. Proc. Natl. Acad. Sci. USA 94:2828-2832.
24. Igo, M. M., A. J. Ninfa, and T. J. Silhavy. 1989. A bacterial environmental sensor that functions as a protein kinase and stimulates transcriptional activation. Genes Dev. 3:598-605.
25. Igo, M. M., A. J. Ninfa, J. B. Stock, and T. J. Silhavy. 1989. Phosphorylation and dephosphorylation of a bacterial transcriptional activator by a transmembrane receptor. Genes Dev. 3:1725-1734.
26. Igo, M. M., and T. J. Silhavy. 1988. EnvZ, a transmembrane environmental sensor of Escherichia coli K-12, is phosphorylated in vitro. J. Bacteriol. 170:5971-5973.
27. Jo, Y., F. Nara, S. Ichihara, T. Mizuno, and S. Mizushima. 1986. Purification and characterization of the OmpR protein, a positive regulator involved in osmoregulatory expression of the ompF and ompC genes in Escherichia coli. J. Biol. Chem. 261:15252-15256.
28. Jones, C. H., P. N. Danese, J. S. Pinkner, T. J. Silhavy, and S. J. Hultgren. Role of periplasmic chaperone, PapD, in periplasmic partitioning and folding of pilus subunit proteins. EMBO J., in press.
29. Jourlin, C., A. Bengrine, M. Chippaux, and V. Mejean. 1996. An unorthodox sensor protein (TorS) mediates the induction of the tor structural genes in response to trimethylamine N-oxide in Escherichia coli. Mol. Microbiol. 20:1297-1306.
30. Kamitani, S., Y. Akiyama, and K. Ito. 1992. Identification and characterization of an Escherichia coli gene required for the formation of correctly folded alkaline phosphatase, a periplasmic enzyme. EMBO J. 11:57-62.
31. Kenney, L. J., M. D. Bauer, and T. J. Silhavy. 1995. Phosphorylation-dependent conformational changes in OmpR, an osmoregulatory DNA-binding protein of Escherichia coli. Proc. Natl. Acad. Sci. USA 92:8866-8870.
32. Kolmar, H., P. R. Waller, and R. T. Sauer. 1996. The DegP and DegQ periplasmic endoproteases of Escherichia coli: specificity for cleavage sites and substrate conformation. J. Bacteriol. 178:5925-5929.
33. Lazar, S. W., and R. Kolter. 1996. SurA assists the folding of Escherichia coli outer membrane proteins. J. Bacteriol. 178:1770-1773.
34. 32 transcription factor. Proc. Natl. Acad. Sci. USA 89:3516-3520.
35. Liberek, K., and C. Georgopoulos. 1993. Autoregulation of the Escherichia coli heat shock response by the DnaK and DnaJ heat shock proteins. Proc. Natl. Acad. Sci. USA 90:11019-11023.
36. Lipinska, B., O. Fayet, L. Baird, and C. Georgopoulos. 1989. Identification, characterization, and mapping of the Escherichia coli htrA gene, whose product is essential for bacterial growth only at elevated temperatures. J. Bacteriol. 171:1574-1584.
37. 32-independent mechanism of heat-inducible transcription. Nucleic Acids Res. 16:10053-10067.
38. Lipinska, B., M. Zylicz, and C. Georgopoulos. 1990. The HtrA (DegP) protein, essential for Escherichia coli survival at high temperatures, is an endopeptidase. J. Bacteriol. 172:1791-1797.
39. Liu, J., and C. T. Walsh. 1990. Peptidyl-prolyl cis-trans-isomerase from Escherichia coli: a periplasmic homolog of cyclophilin that is not inhibited by cyclosporin A. Proc. Natl. Acad. Sci. USA 87:4028-4032.
40. Lukat, G. S., W. R. McCleary, A. M. Stock, and J. B. Stock. 1992. Phosphorylation of bacterial response regulator proteins by low molecular weight phospho-donors. Proc. Natl. Acad. Sci. USA 89:718-722.
41. McCleary, W. R., and J. B. Stock. 1994. Acetyl phosphate and the activation of two-component response regulators. J. Biol. Chem. 269:31567-31572.
42. McEwen, J., and P. Silverman. 1980. Chromosomal mutations of Escherichia coli that alter expression of conjugative plasmid functions. Proc. Natl. Acad. Sci. USA 77:513-517.
43. E, an Escherichia coli heat-inducible σ-factor, is modulated by expression of outer membrane proteins. Genes Dev. 7:2618-2628.
44. Mileykovskaya, E., and W. Dowhan. 1997. The Cpx two-component signal transduction pathway is activated in Escherichia coli mutant strains lacking phosphatidylethanolamine. J. Bacteriol. 179:1029-1034.
45. Missiakas, D., J.-M. Betton, and S. Raina. 1996. New components of protein folding in extracytoplasmic compartments of Escherichia coli SurA, FkpA and Skp/OmpH. Mol. Microbiol. 21:871-884.
46. Missiakas, D., C. Georgopoulos, and S. Raina. 1994. The Escherichia coli dsbC (xprA) gene encodes a periplasmic protein involved in disulfide bond formation. EMBO J. 13:2013-2020.
47. E (RpoE) heat-shock transcription-factor activity by the RseA, RseB and RseC proteins. Mol. Microbiol. 24:355-371.
48. Missiakas, D., and S. Raina. 1997. Signal transduction pathways in response to protein misfolding in the extracytoplasmic compartment of E. coli: role of two new phosphoprotein phosphatases PrpA and PrpB. EMBO J. 16:1670-1685.
49. Missiakas, D., F. Schwager, and S. Raina. 1995. Identification and characterization of a new disulfide isomerase-like protein (DsbD) in Escherichia coli. EMBO J. 14:3414-3424.
50. Mori, K., W. Ma, M. J. Gething, and J. Sambrook. 1993. A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus. Cell 74:743-746.
51. Nakayama, S.-I., and H. Watanabe. 1995. Involvement of cpxA, a sensor of a two-component regulatory system, in the pH-dependent regulation of expression of Shigella sonnei virF gene. J. Bacteriol. 177:5062-5069.
52. Perego, M., P. Glaser, and J. Hoch. 1996. Aspartyl-phosphate phosphatases deactivate the response regulator components of the sporulation signal transduction system in Bacillus subtilis. Mol. Microbiol. 19:1151-1157.
53. Pogliano, J., A. S. Lynch, D. Belin, E. C. C. Lin, and J. Beckwith. 1997. Regulation of Escherichia coli cell envelope proteins involved in protein folding and degradation by the Cpx two-component system. Genes Dev. 11:1169-1182.
54. E, in Escherichia coli. EMBO J. 14:1032-1042.
55. Rouviere, P. E., and C. A. Gross. 1996. SurA, a periplasmic protein with peptidyl-prolyl isomerase activity, participates in the assembly of outer membrane porins. Genes Dev. 10:3170-3182.
56. Russo, F., J. M. Slauch, and T. J. Silhavy. 1993. Mutations that affect separate functions of OmpR the phosphorylated regulator of porin transcription in Escherichia coli. J. Mol. Biol. 231:261-273.
57. Russo, F. D., and T. J. Silhavy. 1991. EnvZ controls the concentration of phosphorylated OmpR to mediate osmoregulation of the porin genes. J. Mol. Biol. 222:567-580.
58. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
59. Shevchik, V. E., G. Condemine, and J. Robert-Baudouy. 1994. Characterization of DsbC, a periplasmic protein of Erwinia chrysanthemi and Escherichia coli with disulfide isomerase activity. EMBO J. 13:2007-2012.
60. Shimoda, N., A. Toyoda-Yamamoto, S. Aoki, and Y. Machida. 1993. Genetic evidence for an interaction between the VirA sensor protein and the ChvE sugar-binding protein of Agrobacterium. J. Biol. Chem. 268:26552-26558.
61. Silhavy, T. J., M. L. Berman, and L. W. Enquist. 1984. Experiments with gene fusions. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
62. Slauch, J. M., and T. J. Silhavy. 1989. Genetic analysis of the switch that controls porin gene expression in Escherichia coli. J. Mol. Biol. 210:281-292.
63. Slauch, J. M., and T. J. Silhavy. 1991. cis-acting ompF mutations that result in OmpR-dependent constitutive expression. J. Bacteriol. 173:4039-4048.
64. Snyder, W. B., L. J. B. Davis, P. N. Danese, C. L. Cosma, and T. J. Silhavy. 1995. Overproduction of NIpE, a new outer membrane lipoprotein, suppresses the toxicity of periplasmic LacZ by activation of the Cpx signal transduction pathway. J. Bacteriol. 177:4216-4223.
65. Strauch, K. L., and J. Beckwith. 1988. An Escherichia coli mutation preventing degradation of abnormal periplasmic proteins. Proc. Natl. Acad. Sci. USA 85:1576-1580.
66. Strauch, K. L., K. Johnson, and J. Beckwith. 1989. Characterization of degP, a gene required for proteolysis in the cell envelope and essential for growth of Escherichia coli at high temperature. J. Bacteriol. 171:2689-2696.
67. 32. Genes Dev. 4:2202-2209.
68. 32 is reduced under conditions of excess heat shock protein production in Escherichia coli. Genes Dev. 3:2003-2010.
69. Tokishita, S., A. Kojima, H. Aiba, and T. Mizuno. 1991. Transmembrane signal transduction and osmoregulation in Escherichia coli. J. Biol. Chem. 266:6780-6785.
70. Tokishita, S., A. Kojima, and T. Mizuno. 1992. Transmembrane signal transduction and osmoregulation in Escherichia coli: functional importance of the transmembrane regions of membrane-located protein kinase, EnvZ. J. Biochem. 111:707-713.
71. Utsumi, R., R. E. Brisette, A. Rampersaud, S. A. Forst, K. Oosawa, and M. Inouye. 1989. Activation of bacterial porin gene expression by a chimeric signal transducer in response to aspartate. Science 245:1246-1249.
72. Wang, Q. P., and J. M. Kaguni. 1989. A novel sigma-factor is involved in expression of the rpoH gene of Escherichia coli. J. Bacteriol. 171:4248-4253.
73. Waukau, J., and S. Forst. 1992. Molecular analysis of the signaling pathway between EnvZ and OmpR in Escherichia coli. J. Bacteriol. 174:1522-1527.
74. Weber, R. F., and P. J. Silverman. 1988. The Cpx proteins of Escherichia coli K-12: structure of the CpxA polypeptide as an inner membrane component. J. Mol. Biol. 203:467-476.
75. Yang, Y., and M. Inouye. 1991. Intermolecular complementation between two defective mutant signal-transduction receptors of Escherichia coli. Proc. Natl. Acad. Sci. USA 88:11057-11061.
76. Yanisch-Perron, C., J. Vieira, and J. Messing. 1985. Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene 33:103-119.