Endothelial cell mitogenesis induced by LPA: Inhibition by thrombospondin-1 and thrombospondin-2

Journal of Laboratory and Clinical Medicine

Volumn 129, Issue 2, 1997, Pages 208-216

  Panetti, Tracee Scalise ^a,b   Chen, Hui ^a   Misenheimer, Tina M ^a   Getzler, Sarah B ^a   Mosher, Deane F ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0031080174     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2143(97)90141-4     Document Type: Article

References (55)

1. Bishop WR, Bell RM. Assembly of phospholipids into cellular membranes: biosynthesis, transmembrane movement and intracellular translocation. Annu Rev Cell Biol 1988;4:579-610.
2. Eichholtz T, Jalink K, Fahrenfort I, Moolenaar WH. The bioactive phospholipid lysophosphatidic acid is released from activated platelets. Biochem J 1993;291:677-80.
3. Fukami K, Takenawa T. Phosphatidic acid that accumulates in platelet-derived growth factor-stimulated Balb/c 3T3 cells is a potential mitogenic signal. J Biol Chem 1992;267:10988-93.
4. Gerrard JM, Robinson P. Identification of the molecular species of lysophosphatidic acid produced when platelets are stimulated by thrombin. Biochem Biophys Res Commun 1989;1001:282-5.
5. Ridley AJ, Hall A. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 1992;70:389-99.
6. Zhang Q, Checovich WJ, Peters DM, Albrecht RM, Mosher DF. Modulation of cell surface fibronectin assembly sites by lysophosphatidic acid. J Cell Biol 1994;127:1447-59.
7. Tokumura A, Fukuzawa K, Yamada S, Tsukatani H. Stimulatory effect of lysophosphatidic acids on uterine smooth muscles of non-pregnant rats. Arch Int Pharmacodyn Ther 1994;245:74-83.
8. Benton AM, Gerrard JM, Michiel T, Kindom SE. Are lysophosphatidic acids or phosphatidic acids involved in stimulus activation coupling in platelets? Blood 1982;60:642-9.
9. van Corven EJ, Groenink A, Jalink K, Eichholtz T, Moolenaar WH. Lysophosphatidate-induced cell proliferation: identification and dissection of signaling pathways mediated by G proteins. Cell 1989;59:45-54.
10. Tigyi G, Dyer DL, Miledi R. Lysophosphatidic acid possesses dual action in cell proliferation. Proc Natl Acad Sci USA 1994;91:1908-12.
11. van Corven EJ, van Rijswijk A, Jalink K, van der Bend RL, van Blitterswijk WJ, Moolenaar WH. Mitogenic action of lysophosphatidic acid and phosphatidic acid on fibroblasts. Dependence on acyl-chain length and inhibition by suramin. Biochem J 1992;281:163-9.
12. Rifkin DB, Moscatelli D. Recent developments in the cell biology of basic fibroblast growth factor. J Cell Biol 1989; 109:1-6.
13. Fantl WJ, Johnson DE, Williams LT. Signalling by receptor tyrosine kinases. Annu Rev Biochem 1993;62:453-81.
14. van Blesen T, Hawes BE, Luttrell DK, et al. Receptor tyrosine kinase- and Gβδ-mediated MAP kinase activation by a common signalling pathway. Nature 1995;376:781-4.
15. raf-1. J Biol Chem 1993;268:20717-20.
16. Hordijk PL, Verlaan I, van Corven EJ, Moolenaar WH. Protein tyrosine phosphorylation induced by lysophosphatidic acid in Rat-1 fibroblasts. Evidence that phosphorylation of MAP kinase is mediated by the Gi-p21ras pathway. J Biol Chem 1994;269:645-51.
17. Cobb MH, Boulton TG, Robbins DJ. Extracellular signal-regulated kinases: ERKs in progress. Cell Regul 1991;2:965-78.
18. Bouck N. Understanding tumor angiogenesis. Contemp Oncol 1994;4:14-23.
19. Folkman J, Shing Y. Angiogenesis. J Biol Chem 1992;267: 10931-4.
20. Auerbach R, Auerbach W, Polakaowski I. Assays for angiogenesis: a review. Pharmacol Ther 1991;51:1-11.
21. Muthukkaruppan V, Auerbach R. Angiogenesis in the mouse cornea. Science 1979;205:1416-8.
22. Good DJ, Polverini PJ, Rastinejad F, et al. A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. Proc Natl Acad Sci USA 1990;87: 6624-8.
23. Vogel T, Guo N-H, Krutzsch HC, et al. Modulation of endothelial cell proliferation, adhesion, and motility by recombinant heparin-binding domain and synthetic peptides from the type 1 repeats of thrombospondin. J Cell Biochem 1993; 53:74-84.
24. Taraboletti G, Roberts D, Liotta LA, Giavazzi R. Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: a potential angiogenesis regulatory factor. J Cell Biol 1990;111:765-72.
25. Iruela-Arispe ML, Bornstein P, Sage H. Thrombospondin exerts an antiangiogenic effect on cord formation by endothelial cells in vitro. Proc Natl Acad Sci USA 1991;88:5026-30.
26. Tolsma SS, Volpert OV, Good DJ, Frazier WA, Polverini PJ, Bouck N. Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity. J Cell Biol 1993;122:497-511.
27. Nicosia RF, Tuszynski GP. Matrix-bound thrombospondin promotes angiogenesis in vitro. J Cell Biol 1994;124:183-93.
28. Schultz-Cherry S, Murphy-Ullrich JE. Thrombospondin causes activation of latent transforming growth factor-β secreted by endothelial cells by a novel mechanism. J Cell Biol 1993;122:923-2.
29. Massague J. The transforming growth factor-beta family [review]. Annu Rev Cell Biol 1990;6:597-641.
30. Schultz-Cherry S, Chen H, Mosher DF, et al. Regulation of transforming growth factor β activation by discrete sequences of thrombospondin 1. J Biol Chem 1995;270:7304-10.
31. Bornstein P, O'Rourke K, Wikstrom K, et al. A second, expressed thrombospondin gene (Thbs2) exists in the mouse genome. J Biol Chem 1991;266:12821-4.
32. Laherty CD, O'Rourke K, Wolf FW, Katz R, Seldin MF, Dixit VM. Characterization of mouse thrombospondin 2 sequence and expression during cell growth and development. J Biol Chem 1992;267:3274-81.
33. Murphy-Ullrich JE, Mosher DF. Interactions of thrombospondin with endothelial cells: receptor-mediated binding and degradation. J Cell Biol 1987;105:1603-11.
34. Frazier WA. Thrombospondin: a modular adhesive glycoprotein of platelets and nucleated cells. J Cell Biol 1987;105:625-32.
35. Chen H, Sottile J, O'Rourke KM, Dixit VM, Mosher DF. Properties of recombinant mouse thrombospondin 2 expressed in Spodoptera cells. J Biol Chem 1994;269:32226-32.
36. Murphy-Ullrich JE, Mosher DF. Localization of thrombospondin in clots formed in situ. Blood 1985;66:1098-104.
37. McKeown-Longo PJ, Mosher DF. Binding of plasma fibronectin to cell layers of human skin fibroblasts. J Cell Biol 1983;97:466-72.
38. Ingber DE, Prusty D, Frangioni JV, Cragoe EJ, Lechene C, Schwartz MA. Control of intracellular pH and growth by fibronectin in capillary endothelial cells. J Cell Biol 1990; 110: 1803-11.
39. Schwartz MA, Ingber DE. Integrating with integrins. Mol Biol Cell 1994;5:389-93.
40. Gospodarowicz D, Savion N, Giguere L. The control of proliferation and differentiation of endothelial cells. In: Nossel HL, Vogel HJ, eds. Pathobiology of the endothelial cell. New York: Academic Press, 1982:19-59.
41. Bagavandoss P, Wilks JW. Specific inhibition of endothelial cell proliferation by thrombospondin. Biochem Biophys Res Commun 1990;170:867-72.
42. Murphy-Ullrich JE, Schultz-Cherry S, Höök M. Transforming growth factor-β complexes with thrombospondin. Mol Biol Cell 1992;3:181-8.
43. Volpert OV, Tolsma SS, Pellerin S, et al. Inhibition of angiogenesis by thrombospondin-2. Biochem Biophys Res Commun 1995;217:326-32.
44. McLees A, Graham A, Malarkey K, Gould GW, Plevin R. Regulation of lysophosphatidic acid-stimulated tyrosine phosphorylation of mitogen-activated protein kinase by protein kinase C- and pertussis toxin-dependent pathways in the endothelial cell line EAhy 926. Biochem J 1995;307: 743-8.
45. Sheibani N, Frazier WA. Thrombospondin 1 expression in transformed endothelial cells restores a normal phenotype and suppresses their tumorigenesis. J Cell Biol 1995;92:6788-92.
46. Sato Y, Rifkin DB. Autocrine activities of basic fibroblast growth factor: regulation of endothelial cell movement, plasminogen activator synthesis, and DNA synthesis. J Cell Biol 1988;107:1199-205.
47. 165 using several concurrent mechanisms. J Biol Chem 1995;270:15059-65.
48. Watson JB, Getzler SB, Mosher DF. Platelet factor 4 modulates the mitogenic activity of basic fibroblast growth factor. J Clin Invest 1994;94:261-8.
49. Folkman J. Tumor angiogenesis factor. Cancer Res 1974;34: 2109-13.
50. Mosher DF. Physiology of thrombospondin. Annu Rev Med 1990;41:85-97.
51. Murphy-Ullrich JE, Mosher DF. Interactions of thrombospondin with cells in culture: rapid degradation of both soluble and matrix thrombospondin. Semin Thromb Hemost 1987;13:343-51.
52. Chen H, Strickland DK, Mosher DF. Metabolism of thrombospondin 2. Binding and degradation by 3T3 cells and glycosaminoglycan-variant Chinese hamster ovary cells. J Biol Chem 1996;271:15993-9.
53. Exton JH. Signaling through phosphatidylcholine breakdown. J Biol Chem 1990;265:1-4.
54. Tigyi G, Hong L, Yakuba M, Parfenova H, Shibata M, Leffler CW. Lysophosphatidic acid alters cerebrovascular reactivity in piglets. Am J Physiol 1995;268:H2048-55.
55. Mumby SM, Abbott-Brown D, Raugi GJ, Bornstein P. Regulation of thrombospondin secretion by cells in culture. J Cell Physiol 1984; 120:280-288.