Thrombospondin-1 and -2 messenger RNA expression in normal, benign, and neoplastic human breast tissues: Correlation with prognostic factors, tumor angiogenesis, and fibroblastic desmoplasia

Cancer Research

Volumn 57, Issue 3, 1997, Pages 396-399

  Bertin, Nicolas ^a   Clezardin, Philippe ^b   Kubiak, Robert ^c,d   Frappart, Lucien ^a  

^a CNRS UMR 5641   (Poland)

^b INSERM Research Unit 403   (Poland)

^c EDOUARD HERRIOT HOSPITAL   (France)

^d MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; THROMBOSPONDIN; THROMBOSPONDIN 1; THROMBOSPONDIN 2; UNCLASSIFIED DRUG;

ANGIOGENESIS; ARTICLE; BREAST CARCINOGENESIS; FEMALE; FIBROMA; GROWTH REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROGNOSIS; QUANTITATIVE DIAGNOSIS; RNA ANALYSIS;

ADULT; AGED; BREAST; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; FEMALE; HUMANS; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; PROGNOSIS; RNA, MESSENGER; THROMBOSPONDINS;

EID: 0031057680     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Wong, S. Y., Purdie, A. T., and Han, P. Thrombospondin and other possible related matrix proteins in malignant and benign breast disease: an immunohistochemical study. Am. J. Pathol, 140: 1473-1482, 1992.
2. Clezardin, P., Frappart, L., Clerget, M., Pechoux, C., and Delmas, P. D. Expression of thrombospondin (TSP1) and its receptors (CD36 and CD51) in normal, hyperplastic, and neoplastic human breast. Cancer Res., 53: 1421-1430, 1993.
3. Tuszynski, G. P., and Nicosia, R. F. Localization of thrombospondin and its CSVTCG-specific receptor in human breast carcinoma. Lab. Invest., 70: 228-233, 1994.
4. Grégoire, M., and Lieubeau, B. The role of fibroblasts in tumor behavior. Cancer Metastasis Rev., 14: 339-350, 1995.
5. Roberts, D. D. Regulation of tumor growth and metastasis by thrombospondin-1. FASBB J., 10: 1183-1191, 1996.
6. Tuszynski, G. P., and Nicosia, R. F. The role of thrombospondin-1 in tumor progression and angiogenesis. BioEssays, 18: 71-76, 1996.
7. Dameron, K. M., Volpert, O. V., Tainsky, M. A., and Bouck, N. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science (Washington DC), 265: 1582-1584, 1994.
8. Nicosia, R. F., and Tuszynski, G. P. Matrix-bound thrombospondin promotes angiogenesis in vitro. J. Cell Biol., 124: 183-193, 1994.
9. Bornstein, P., and Sage, E. H. Thrombospondins. Methods Enzymol., 245: 62-85, 1994.
10. Volpert, O. V., Tolsma, S. S., Pellerin, S., Feige, J. J., Chen, H., Mosher, D. F., and Bouck, N. Inhibition of angiogenesis by thrombospondin-2. Biochem. Biophys. Res. Commun., 217: 326-332, 1995.
11. Gasparini, G., and Harris, A. L. Clinical importance of the determination of tumor angiogenesis in breast carcinoma: much more than a new prognostic tool. J. Clin. Oncol., 13: 765-782, 1995.
12. Pratt, D. A., Miller, W. R., and Dawes, J. Thrombospondin in malignant and non-malignant breast tissue. Eur. J. Cancer Clin. Oncol., 25: 343-350, 1989.
13. Weinstat-Saslow, D. L., Zabrenetzky, V. S., VanHoutte, K., Frazier, W. A., Roberts, D. D., and Steeg, P. S. Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis. Cancer Res., 54: 6504-6511, 1994.
14. Axelsson, K., Ljung, B. M., Moore, D. H., II, Thor, A. D., Chew, K. L., Edgerton, S. M., Smith, S. H., and Mayall, B. H. Tumor angiogenesis as a prognostic assay for invasive ductal breast carcinoma. J. Natl. Cancer Inst., 87: 997-1008, 1995.