Reduction of immunoreactivity of bovine β-lactoglobulin upon combined physical and proteolytic treatment

Journal of Dairy Research

Volumn 70, Issue 1, 2003, Pages 51-59

  Bonomi, Francesco ^a   Fiocchi, Alessandro ^a   Frøkiær, Hanne ^b   Gaiaschi, Antonella ^a   Iametti, Stefania ^a   Poiesi, Claudio ^c   Rasmussen, Patrizia ^a,b   Restani, Patrizia ^a   Rovere, Pierpaolo ^d  

^a UNIVERSITY OF MILAN   (Italy)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^c UNIVERSITY OF BRESCIA   (Italy)

^d Flow Pressure Systems   (Sweden)

Author keywords

lactoglobulin; High pressure; Protein immunoreactivity; Proteolytic enzymes

Indexed keywords

ATMOSPHERIC PRESSURE; BLOTTING, WESTERN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHYMOTRYPSIN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; LACTOGLOBULINS; TEMPERATURE; TRYPSIN;

BOVINAE;

EID: 0037326966     PISSN: 00220299     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0022029902005678     Document Type: Article

References (38)

1. Bonde M, Frøkiær H & Pepper DS 1991 Selection of monoclonal antibodies for immuno affinity chromatography: model studies with antibodies against soy bean trypsin inhibitor. Journal of Biochemical and Biophysical Methods 23 73-82
2. Bonomi F, Iametti S, Castagna C, Dall'Aglio GF & Rovere PP 1999 Proteolysis of bovine β-lactoglobulin and chicken egg albumin during treatment at high pressure. In Advances in high pressure bioscience and biotechnology, pp. 289-292 (Ed. H Ludwig). Heidelberg: Springer-Verlag
3. Bonomi F, lametti S, Rasmussen P, Restani P & Rovere PP 2000 Advances in the combined application of enzymatic and physical treatments for reducing food allergenicity. High Pressure Research 19 175-181
4. Brownlow S, Morais Cabral JH, Cooper R, Flower DR, Yewdall SJ, Polikarpov I, North ACT & Sawyer L 1997 Bovine β-lactoglobulin at 1.8 Å resolution - still an enigmatic lipocalin. Structure 5 481-495
5. Businco L, Cantani A, Longhi A & Gianpietro PG 1989 Anaphylactic reactions to a cow's milk whey protein hydrolysate (Alfa-Rè, Nestlé) in infants with cow's milk allergy. Annals of Allergy 62 333-335
6. Cairoli S, Iametti S & Bonomi F 1994 Reversible and irreversible modifications of β-lactoglobulin upon heating. Journal of Protein Chemistry 13 347-354
7. Davis PJ & Williams SC 1998 Protein modification by thermal processing. Allergy 53 102-105
8. Dufour E, Herve G & Haertle T 1995 Hydrolysis of beta-lactoglobulin by thermolysin and pepsin under high hydrostatic pressure. Biopolymers 35 475-483
9. Fessas D, Iametti S, Schiraldi A & Bonomi F 2001 Thermal unfolding of monomeric and dimeric betalactoglobulins. European Journal of Biochemistry 268 5439-5448
10. Funtenberger S, Dumay E & Cheftel JC 1997 High pressure promotes beta-lactoglobulin aggregation through SH/S-S interchange reactions. Journal of Agricultural and Food Chemistry 45 912-921
11. Heremans L & Heremans K 1989 Raman spectroscopic study of the changes in secondary structure of chymotrypsin: effect of pH and pressure on the salt bridge. Biochimica Biophysica Acta 999 192-197
12. Iametti S, Cairoli S, De Gregori B & Bonomi F 1995 Modifications of high-order structures upon heating of β-lactoglobulin: dependence on the protein concentration. Journal of Agricultural and Food Chemistry 43 53-58
13. Iametti S, De Gregori B, Vecchio G & Bonomi F 1996 Modifications occur at different structural levels during the heat denaturation of β-lactoglobulin. European Journal of Biochemistry 237 106-112
14. Iametti S, Donnizzelli E, Pittia P, Rovere P, Squarcina N & Bonomi F 1999 Properties of a soluble form of high-pressure treated egg albumen. Journal of Agricultural and Food Chemistry 47 3611-3616
15. Iametti S, Donnizzelli E, Vecchio G, Rovere P, Gola S & Bonomi F 1998a Macroscopic and structural consequences of high-pressure treatment of ovalbumin solutions. Journal of Agricultural and Food Chemistry 46 3521-3527
16. Iametti S, Scaglioni L, Mazzini S, Vecchio G & Bonomi F 1998b Structural features and reversible association of different quaternary structures of β-lactoglobulin. Journal of Agricultural and Food Chemistry 46 2159-2166
17. Iametti S, Transidico P, Bonomi F, Vecchio G, Pittia P, Rovere P & Dall'Aglio G 1997 Molecular modifications of β-lactoglobulin upon exposure to high pressures. Journal of Agricultural and Food Chemistry 45 23-29
18. Kuntz ID Jr & Kauzmann W 1974 Hydration of proteins and polypeptides. Advances in Protein Chemistry 28 239-345
19. Kunugi S, Kitayaki M, Yanagi Y, Tanaka N, Lange R & Balny C 1997 The effect of high-pressure on thermolysin. European Journal of Biochemistry 248 567-574
20. Maynard F, Weingand A, Hau J & Jost R 1998 Effects of high-pressure treatment on the tryptic hydrolysis of bovine β-lactoglobulin AB. International Dairy Journal 8 125-133
21. Meisel H & Bockelmann W 1999 Bioactive peptides encrypted in milk proteins: proteolytic activation and thropho-functional properties. Antonie van Leeuwenhoek 76 207-215
22. Moller RE, Stapelfeldt H & Skibsted LH 1998 Thiol reactivity in pressure-unfolded beta-lactoglobulin - antioxidative properties and thermal refolding. Journal of Agricultural and Food Chemistry 46 425-430
23. Needs EC, Stenning RA, Gill AL, Ferragut V & Rich GT 2000a High-pressure treatment of milk: effects on casein micelle structure and on enzymic coagulation. Journal of Dairy Research 67 31-42
24. Needs EC, Capellas M, Bland AP, Manoj P, MacDougal D & Paul G 2000b Comparison of heat and pressure treatments of skim milk, fortified with whey protein concentrate, for set yogurt preparation: effects on milk proteins and gel structure. Journal of Dairy Research 67 329-348
25. Neuhoff V, Arold N, Taube D & Ehrhardt W 1988 Improved staining of proteins in polyacrylamide gels including isoelectric focusing gels with clear background at nanogram sensitivity using Coomassie Brilliant Blue G-250 and R-250. Electrophoresis 9 550-552
26. Okamoto M, Hayashi R, Enomoto A, Kaminogawa S & Yamauchi K 1991 High-pressure proteolytic digestion of food proteins: selective elimination of β-lactoglobulin in bovine milk whey concentrate. Agricultural Biological Chemistry 55 1253-1257
27. Plebani A, Albertini A, Scotta S & Ugazio AG 1990 Antibodies to hydrolysates of cow's milk proteins in children with cow's milk allergy. Annals of Allergy 64 279-280
28. Ragno V, Giampietro PG, Bruno L & Businco L 1993 Allergenicity of milk protein hydrolysate formulae in children with cow's milk allergy. European Journal of Pediatrics 152 760-762
29. Restani P, Velonà T, Plebani A, Ugazio AG, Poiesi C, Muraro A & Galli CL 1995 Evaluation by SDS-PAGE and immunoblotting of residual antigenicity in hydrolysed protein formulas. Clinical and Experimental Allergy 25 651-658
30. Restani P, Plebani A, Velonà T, Cavagni G, Ugazio AG, Poiesi C, Muraro A & Galli CL 1996 Use of immunoblotting and monoclonar antibodies to evaluate the residual antigenic activity of milk protein hydrolysed formulae. Clinical and Experimental Allergy 26 1182-1187
31. Roefs SPFM & De Kruif KG 1994 A model for the denaturation and aggregation of beta-lactoglobulin. European Journal of Biochemistry 226 883-889
32. Rondanini A, Bonomi F, Iametti S, Lucisano M, Pagani MA & Rovere PP 2000 On the nature and the practical relevance of the molecular modifications induced in wheat proteins by high pressure treatment. High Pressure Research 19 167-173
33. Rosendal A & Barkholt V 2000 Detection of potentially allergenic material in 12 hydrolyzed milk formulas. Journal of Dairy Science 83 2200-2210
34. Ruan K, Lange R, Bec N & Balny C 1997 A stable partly denatured state of trypsin induced by high hydrostatic pressure. Biochemical and Biophysical Research Communications 239 150-154
35. Sampson HA, James JM & Bernishel-Broadbent J 1992 Safety of an amino acid-derived infant formula in children allergic to cow milk. Pediatrics 90 463-465
36. Saylor JD & Bahna SL 1991 Anaphylaxis to casein hydrolysate formula. Journal of Pediatrics 118 71-74
37. Stapelfeldt H, Petersen PH, Kristiansen KR, Qvist KB & Skibsted LH 1996 Effect of high hydrostatic pressure on the enzymic hydrolysis of beta-lactoglobulin B by trypsin, thermolysin and pepsin. Journal of Dairy Research 63 111-118
38. Van Willige RWG & Fitzgerald RJ 1995 Tryptic and chymotryptic hydrolysis of β-lactoglobulin A, B and AB at ambient and high pressure. Milchwissenschaft 50 183-188