Bidirectional transcytosis of IgG by the rat neonatal Fc receptor expressed in a rat kidney cell line: A system to study protein transport across epithelia

Journal of Cell Science

Volumn 113, Issue 7, 2000, Pages 1277-1285

  McCarthy, Kevin M ^a   Yoong, Yinlee ^a,b   Simister, Neil E ^a  

^a BRANDEIS UNIVERSITY   (United States)

^b MAYO CLINIC   (United States)

Author keywords

Cell polarity; FcRn; Transcytosis

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; FC RECEPTOR; IMMUNOGLOBULIN G; PHOSPHATIDYLINOSITOL 3 KINASE; RECEPTOR SUBUNIT; WORTMANNIN;

ANIMAL CELL; ANIMAL EXPERIMENT; APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; EPITHELIUM; KIDNEY CELL CULTURE; KIDNEY COLLECTING TUBULE; KIDNEY MEDULLA; LIGAND BINDING; MICROTUBULE; MONOLAYER CULTURE; NEWBORN; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; TRANSCYTOSIS;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, NEWBORN; BIOLOGICAL TRANSPORT; CELL LINE; CELL POLARITY; DOGS; EPITHELIAL CELLS; HISTOCOMPATIBILITY ANTIGENS CLASS I; IMMUNOGLOBULIN G; KIDNEY; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RATS; RECEPTORS, FC; TRANSFECTION;

ANIMALIA;

EID: 0034058526     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Ahouse, J. J., Hagerman, C. L., Mittal, P., Gilbert, D. J., Copeland, N. G., Jenkins, N. A. and Simister, N. E. (1993). A mouse MHC class-I-like Fc receptor encoded outside the MHC. J. Immunol. 151, 6076-6088.
2. +-ATPase in cultured inner medullary collecting duct cells. Am. J. Physiol. 276, C758-763.
3. Apodaca, G., Cardone, M. H., Whiteheart, S. W., DasGupta, B. R. and Mostov, K. E. (1996). Reconstitution of transcytosis in SLO-permeabilized MDCK cells: existence of an NSF-dependent fusion mechanism with the apical surface of MDCK cells. EMBO J. 15, 1471-1481.
4. Arcaro, A. and Wymann, M. P. (1993). Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses. Biochem. J. 296, 297-301.
5. Benlounes, N., Chedid, R., Thuillier, F., Desjeux, J. F., Rousselet, F. and Heyman, M. (1995). Intestinal transport and processing of immunoglobulin G in the neonatal and adult rat. Biol. Neonate 67, 254-263.
6. Berryman, M. and Rodewald, R. (1995). Beta 2-microglobulin co-distributes with the heavy chain of the intestinal IgG-Fc receptor throughout the transepithelial transport pathway of the neonatal rat. J. Cell Sci. 108, 2347-2360.
7. Borvak, J., Richardson, J., Medesan, C., Antobe, F., Radu, C., Simionescu, M., Ghetie, V. and Ward, E. S. (1998). Functional expression of the MHC class I-related receptor, FcRn, in endothelial cells of mice. Int. Immunol. 10, 1289-1298.
8. + cytolytic T cells. Nature 344, 742-746.