Dipyrimidine-based inhibitors of HIV-1 integrase

Expert Opinion on Investigational Drugs

Volumn 12, Issue 2, 2003, Pages 289-292

  Neamati, Nouri ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

AntiHIV; Antiviral; Drug discovery; Integrase; Small molecule inhibitor

Indexed keywords

1 [5 (4 FLUOROBENZYL) 2 FURYL] 3 (1,2,4 TRIAZOL 3 YL) 1,3 PROPANEDIONE; ANTIRETROVIRUS AGENT; BENZENE DERIVATIVE; COUMARIN DERIVATIVE; CYSTEINE; HYDRAZIDE DERIVATIVE; INTEGRASE; INTEGRASE INHIBITOR; KETONE DERIVATIVE; L 708 906; MAGNESIUM; NELFINAVIR; NEVIRAPINE; POL PROTEIN; PROTEINASE; PROTEINASE INHIBITOR; PYRIMIDINE DERIVATIVE; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; THIAZEPINE DERIVATIVE; UNCLASSIFIED DRUG; V 165; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; CLINICAL TRIAL; CONCENTRATION RESPONSE; CYTOTOXICITY; DRUG APPROVAL; DRUG BINDING; DRUG MECHANISM; DRUG POTENCY; DRUG POTENTIATION; DRUG SELECTIVITY; DRUG STABILITY; DRUG STRUCTURE; DRUG TARGETING; ENZYME INHIBITION; GENETIC CODE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IC 50; IN VITRO STUDY; NONHUMAN; STRUCTURAL GENE; VIRUS RESISTANCE;

ACETOACETATES; ANIMALS; ANTI-HIV AGENTS; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HUMANS; PYRIMIDINES;

EID: 0037315284     PISSN: 13543784     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543784.12.2.289     Document Type: Article

References (16)

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