The characterization of somatic APC mutations in colonic adenomas and carcinomas in Ashkenazi Jews with the APC I1307K variant using linkage disequilibrium

Journal of Pathology

Volumn 199, Issue 2, 2003, Pages 146-151

  Zauber, N Peter ^a   Sabbath Solitare, Marlene ^a   Marotta, Stephen P ^a   Bishop, D Timothy ^b  

^a SAINT BARNABAS MEDICAL CENTER   (United States)

^b ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

APC gene; Ashkenazi Jews; I1307K mutation; Linkage disequilibrium; Loss of heterozygosity; Microsatellite repeat locus

Indexed keywords

APC PROTEIN; DNA; PLASMID VECTOR;

AGED; ALLELE; ARTICLE; CANCER CLASSIFICATION; CODON; COLON ADENOMA; COLON CARCINOGENESIS; COLON CARCINOMA; COLON POLYPOSIS; CONTROLLED STUDY; GENE ISOLATION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE MUTATION; GENETIC SCREENING; GENETIC VARIABILITY; GEOGRAPHIC DISTRIBUTION; HEMICOLECTOMY; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; JEW; MALE; MICROSATELLITE INSTABILITY; MOLECULAR CLONING; POLYMERASE CHAIN REACTION; POPULATION DISTRIBUTION; POPULATION RESEARCH; PRIORITY JOURNAL; SOMATIC MUTATION;

ADENOMA; AGED; ALLELES; CARCINOMA; COLORECTAL NEOPLASMS; DNA, NEOPLASM; GENES, APC; GENETIC MARKERS; GENOTYPE; HUMANS; JEWS; LINKAGE DISEQUILIBRIUM; LOSS OF HETEROZYGOSITY; MALE; MICROSATELLITE REPEATS; MUTATION; POLYMERASE CHAIN REACTION;

EID: 0037314547     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.1226     Document Type: Article

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