Comparison of allelic ratios from paired blood and paraffin-embedded normal tissue for use in a polymerase chain reaction to assess loss of heterozygosity

Molecular Diagnosis

Volumn 4, Issue 1, 1999, Pages 29-35

  Peter Zauber, N ^a   Sabbath Solitare, Marlene ^a   Marotta, Stephen P ^a   McMahon, Laura ^a   Timothy Bishop, D ^b  

^a SAINT BARNABAS MEDICAL CENTER   (United States)

^b ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

Allelic ratios; LOH

Indexed keywords

ALLELE; ARTICLE; DNA DETERMINATION; GENE AMPLIFICATION; GENE LOSS; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; POLYMERASE CHAIN REACTION; TISSUE PREPARATION;

EID: 0032941934     PISSN: 10848592     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1084-8592(99)80047-2     Document Type: Article

References (2)

1. Solomon E, Voss R, Hall V, Bodmer WF, Jass JR, Jeffreys AJ, Lucibello FC, Patel I, Rider SH: Chro-mosome 5 allele loss in human colorectal carcinomas. Nature 1987;328:616-619
2. Ponder B: Gene losses in human tumors. Nature 1988;335:400-402