Somatic instability of the APC I1307K allele in colorectal neoplasia

Cancer Research

Volumn 58, Issue 18, 1998, Pages 4040-4043

  Gryfe, Robert ^a,b   Di Nicola, Nando ^a   Gallinger, Steven ^a,b   Redston, Mark ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; CANCER GENETICS; COLORECTAL CANCER; GENE MUTATION; GENETIC VARIABILITY; HETEROZYGOSITY LOSS; HUMAN; JEW; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SOMATIC CELL GENETICS;

ADENOMATOUS POLYPOSIS COLI; ALLELES; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; GENE DELETION; GENES, APC; GERM-LINE MUTATION; HUMANS; JEWS; MICROSATELLITE REPEATS; POINT MUTATION;

EID: 0032530139     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Laken, S. J., Petersen, G. M., Gruber, S. B., Oddoux, C., Ostrer, H., Giardiello, F. M., Hamilton, S. R., Hampel, H., Markowitz, A., Klimstra, D., Jhanwar, S., Winawer, S., Offit, K., Luce, M. C., Kinzler, K. W., and Vogelstein, B. Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC. Nat. Genet., 17: 79-83, 1997.
2. Parsons, R., Myeroff, L. L., Liu, B., Willson, J. K. V., Markowitz, S. D., Kinzler, K. W., and Vogelstein, B. Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer. Cancer Res., 55: 5548-5550, 1995.
3. Aaltonen, L. A., Peltomaki, P., Leach, F. S., Sistonen, P., Pylkkanen, L., Mecklin, J-P., Jarvinen, H., Powell, S. M., Jen, J., Hamilton, S. R., Petersen, G. M., Kinzler, K. W., Vogelstein, B., and de la Chapelle, A. Clues to the pathogenesis of familial colorectal cancer. Science (Washington DC), 260: 812-816, 1993.
4. Thibodeau, S. N., Bren, G., and Schaid, D. Microsatellite instability in cancer of the proximal colon. Science (Washington DC), 260: 816-819, 1993.
5. Ionov, Y., Peinado, M. A., Malkhosyan, S., Shibata, D., and Perucho, M. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature (Lond.), 363: 558-561, 1993.
6. Clayton, E. W., Steinberg, K. K., Khoury, M. J., Thomson, E., Andrews, L., Kahn, M. J., Kopelman, L. M., and Weiss, J. O. Informed consent for genetic research on stored tissue samples. J. Am. Med. Assoc., 274: 1786-1792, 1995.
7. Jen, J., Kim, H., Piantadosi, S., Liu, Z. F., Levitt, R. C., Sistonen, P., Kinzler, K. W., Vogelstein, B., and Hamilton, S. R. Allelic loss of chromosome 18q and prognosis in colorectal cancer. N. Engl. J. Med., 331: 213-221, 1994.
8. Redston, M. S., Caldas, C., Seymour, A. B., Hruban, R. H., da Costa, L., Yeo, C. J., and Kern, S. E. p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions. Cancer Res., 54: 3025-3033, 1994.
9. Dietmaier, W., Wallinger, S., Bocker, T., Kullman, F., Fishel, R., and Ruschoff, J. Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression. Cancer Res., 57: 4749-4756, 1997.
10. Hoang, J-M., Cottu, P. H., Thuille, B., Salmon, R. J., Thomas, G., and Hamelin, R. BAT-26 an indicator of the replication error phenotype in colorectal cancers and cell lines. Cancer Res., 57: 300-303, 1997.
11. Miyaki, M., Konishi, M., Kikuchi-Yanoshita, R., Enomoto, M., Igari, T., Tanaka, K., Muraoka, M., Takahashi, H., Amada, Y., Fukayama, M., Maeda, Y., Iwama, T., Mishima, Y., Mori, T., and Koike, M. Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors. Cancer Res., 54: 3011-3020, 1994.
12. Jen, J., Powell, S. M., Papadopoulos, N., Smith, K. J., Hamilton, S. R., Vogelstein, B., and Kinzler, K. W. Molecular determinants of dysplasia in colorectal lesions. Cancer Res., 54: 5523-5526, 1994.
13. Olschwang, S., Hamelin, R., Laurent-Puig, P., Thuille, B., De Rycke, Y., Li, Y. J., Muzeau, F., Girodet, J., Salmon, R. J., and Thomas, G. Alternative genetic pathways in colorectal carcinogenesis. Proc. Natl. Acad. Sci. USA, 94: 12122-12127, 1997.
14. Sia, E. A., Kokoska, R. J., Dominska, M., Greenwell, P., and Petes, T. D. Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genes. Mol. Cell. Biol., 17: 2851-2858, 1997.
15. Strand, M., Prolla, T. A., Liskay, R. M., and Petes. T. D. Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. Nature (Lond.), 365: 274-276, 1993.
16. Tran, H. T., Keen, D., Kricker, M., Resnick, M. A., and Gordenin, D. A. Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants. Mol. Cell. Biol., 17: 2859-2865, 1997.
17. Sparks, A. B., Morin, P. J., Vogelstein, B., and Kinzler, K. W. Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer. Cancer Res., 58: 1130-1134, 1998.
18. Cannon-Albright, L. A., Skolnick, M. H., Bishop, D. T., Lee, R. G., and Burt, R. W. Common inheritance of susceptibility to colonie adenomatous polyps and associated colorectal cancers. N. Engl. J. Med., 319: 533-537, 1988.
19. Kinzler, K. W., and Vogelstein, B. Lessons from hereditary colorectal cancer. Cell, 87: 159-170, 1996.
20. Parsons, R., Li, G-M., Longley, M. J., Fang, W-h., Papadopoulos, N., Jen, J., de la Chapelle, A., Kinzler, K. W., Vogelstein, B., and Modrich, P. Hypermutability and mismatch repair deficiency in RER+ tumor cells. Cell, 75: 1227-1236, 1993.