-
2
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0033953433
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Single-target molecule detection with nonbleaching multicolor optical immunolabels
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This paper introduces the use of protein-conjugated PRPs for single-target molecule detection in several different biological assays; for example, an ultrasensitive three-component assay where the signal results from the rapid identification and counting of individual PRPs
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Schultz S., Smith D.R., Mock J.J., Schultz D.A. Single-target molecule detection with nonbleaching multicolor optical immunolabels. Proc. Natl. Acad. Sci. U.S.A. 97:2000;996-1001 This paper introduces the use of protein-conjugated PRPs for single-target molecule detection in several different biological assays; for example, an ultrasensitive three-component assay where the signal results from the rapid identification and counting of individual PRPs.
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Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 996-1001
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Schultz, S.1
Smith, D.R.2
Mock, J.J.3
Schultz, D.A.4
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4
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0030768397
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Selective colorimetric detection of polynucleotides based on the distance-dependent optical properties of gold nanoparticles
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Elghanian R., Storhoff J.J., Mucic R.C., Letsinger R.L., Mirkin C.A. Selective colorimetric detection of polynucleotides based on the distance-dependent optical properties of gold nanoparticles. Science. 277:1997;1078-1081.
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Science
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Elghanian, R.1
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Mucic, R.C.3
Letsinger, R.L.4
Mirkin, C.A.5
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6
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0030109049
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A scanning near-field optical microscope for the imaging of magnetic domains in reflection
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Silva T.J., Schultz S. A scanning near-field optical microscope for the imaging of magnetic domains in reflection. Rev. Sci. Instrum. 67:1996;715-725.
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Rev. Sci. Instrum.
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Silva, T.J.1
Schultz, S.2
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7
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85031268007
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Development of a scanned near-field optical microscope for magneto-optic Kerr imaging of magnetic domains with 10 nm resolution
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Arc-et-Senans, France, Edited by Pohl D, Courjon D. Kluwer Academic
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Silva TJ, Schultz S: Development of a scanned near-field optical microscope for magneto-optic Kerr imaging of magnetic domains with 10 nm resolution. In Proceedings of the NATO Advanced Research Workshop in Near Field Optics 1993; Arc-et-Senans, France, Edited by Pohl D, Courjon D. Kluwer Academic: 1992.
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(1992)
Proceedings of the NATO Advanced Research Workshop in Near Field Optics 1993
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Silva, T.J.1
Schultz, S.2
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8
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0026461578
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Development toward magneto-optic Kerr scanned near-field optical microscope with 10-nm resolution
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Edited by Manne S. Bellingham, WA: SPIE Society
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Schultz S, Silva TJ: Development toward magneto-optic Kerr scanned near-field optical microscope with 10-nm resolution. In Scanning Probe Microscopies. Edited by Manne S. Bellingham, WA: SPIE Society; 1992:31-35.
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Scanning Probe Microscopies
, pp. 31-35
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Schultz, S.1
Silva, T.J.2
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9
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0034023478
-
Use of a steroid cyclic disulfide anchor in constructing gold nanoparticle-oligonucleotide conjugates
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Describes a di-thiol group used to anchor oligonucleotides to gold PRPs. The resultant conjugates have improved stability relative to conjugates prepared with mono-thiol oligonucleotides
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Letsinger R.L., Elghanian R., Viswanadham G., Mirkin C.A. Use of a steroid cyclic disulfide anchor in constructing gold nanoparticle-oligonucleotide conjugates. Bioconjug. Chem. 11:2000;289-291 Describes a di-thiol group used to anchor oligonucleotides to gold PRPs. The resultant conjugates have improved stability relative to conjugates prepared with mono-thiol oligonucleotides.
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Bioconjug. Chem.
, vol.11
, pp. 289-291
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Letsinger, R.L.1
Elghanian, R.2
Viswanadham, G.3
Mirkin, C.A.4
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10
-
-
0036529538
-
Multiple thiol-anchor capped DNA-gold nanoparticle conjugates
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Describes a tri-thiol-capped oligonucleotide gold PRP conjugate that has greater stability than either the mono- or di-thiol oligonucleotide gold PRP conjugates. Importantly, this anchoring molecule can stabilize the larger diameter (>50 nm) gold PRPs which can be viewed individually
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Li Z., Jin R.C., Mirkin C.A., Letsinger R.L. Multiple thiol-anchor capped DNA-gold nanoparticle conjugates. Nucleic Acids Res. 30:2002;1558-1562 Describes a tri-thiol-capped oligonucleotide gold PRP conjugate that has greater stability than either the mono- or di-thiol oligonucleotide gold PRP conjugates. Importantly, this anchoring molecule can stabilize the larger diameter (>50 nm) gold PRPs which can be viewed individually.
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Nucleic Acids Res.
, vol.30
, pp. 1558-1562
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Li, Z.1
Jin, R.C.2
Mirkin, C.A.3
Letsinger, R.L.4
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11
-
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0034802588
-
DNA-modified core-shell Ag/Au nanoparticles
-
A method for preparing gold-coated silver PRPs is described. This is important because it allows PRPs that retain the spectral characteristics of silver to be functionalized using the more robust procedures that have been developed for gold
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Cao Y.W., Jin R., Mirkin C.A. DNA-modified core-shell Ag/Au nanoparticles. J. Am. Chem. Soc. 123:2001;7961-7962 A method for preparing gold-coated silver PRPs is described. This is important because it allows PRPs that retain the spectral characteristics of silver to be functionalized using the more robust procedures that have been developed for gold.
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(2001)
J. Am. Chem. Soc.
, vol.123
, pp. 7961-7962
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Cao, Y.W.1
Jin, R.2
Mirkin, C.A.3
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12
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0034820154
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DNA-block copolymer conjugates
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Watson K.J., Park S.J., Im J.H., Nguyen S.T., Mirkin C.A. DNA-block copolymer conjugates. J. Am. Chem. Soc. 123:2001;5592-5593.
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J. Am. Chem. Soc.
, vol.123
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Watson, K.J.1
Park, S.J.2
Im, J.H.3
Nguyen, S.T.4
Mirkin, C.A.5
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13
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0000870882
-
Composite plasmon resonant nanowires
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Individual multisegment plasmon-resonant nanorods were optically characterized. They have possible use as unique identifiers in biological applications
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Mock J.J., Oldenburg S.J., Smith D.R., Schultz D.A., Schultz S. Composite plasmon resonant nanowires. Nano Letters. 2:2002;465-469 Individual multisegment plasmon-resonant nanorods were optically characterized. They have possible use as unique identifiers in biological applications.
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Nano Letters
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, pp. 465-469
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Mock, J.J.1
Oldenburg, S.J.2
Smith, D.R.3
Schultz, D.A.4
Schultz, S.5
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14
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0037200020
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Nanoparticles with Raman spectroscopic fingerprints for DNA and RNA detection
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Cao Y.W., Jin R., Mirkin C.A. Nanoparticles with Raman spectroscopic fingerprints for DNA and RNA detection. Science. 297:2002;1537-1540.
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Science
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Cao, Y.W.1
Jin, R.2
Mirkin, C.A.3
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15
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0033230274
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Immunoassay readout method using extrinsic Raman labels adsorbed on immunogold colloids
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Ni J., Lipert R.J., Dawson G.B., Porter M.D. Immunoassay readout method using extrinsic Raman labels adsorbed on immunogold colloids. Anal. Chem. 71:1999;4903-4908.
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Ni, J.1
Lipert, R.J.2
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0031037501
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Probing single molecules and single nanoparticles by surface-enhanced Raman scattering
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Nie S., Emory S.R. Probing single molecules and single nanoparticles by surface-enhanced Raman scattering. Science. 275:1997;1102-1106.
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Science
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Nie, S.1
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Single molecule detection using surface-enhanced Raman scattering (SERS)
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Kneipp K., Wang Y., Kneipp H., Perelman L.T., Itzkan I., Dasari R., Feld M.S. Single molecule detection using surface-enhanced Raman scattering (SERS). Phys. Rev. Lett. 78:1997;1667-1670.
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Dasari, R.6
Feld, M.S.7
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18
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0037091278
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Shape effects in plasmon resonance of individual colloidal silver nanoparticles
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A systematic study of the effect of size and shape on the plasmon-resonant peak of individual silver PRPs. Illustrates that specific geometrical shapes give rise to a distinct spectral response
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Mock J.J., Barbic M., Smith D.R., Schultz D.A., Schultz S. Shape effects in plasmon resonance of individual colloidal silver nanoparticles. J. Chem. Phys. 116:2002;6755-6759 A systematic study of the effect of size and shape on the plasmon-resonant peak of individual silver PRPs. Illustrates that specific geometrical shapes give rise to a distinct spectral response.
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Mock, J.J.1
Barbic, M.2
Smith, D.R.3
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Schultz, S.5
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20
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0035928129
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Nanosphere lithography: A versatile nanofabrication tool for studies of size-dependent nanoparticle optics
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Reviews the use of nanosphere lithography for the production of PRPs of different shape. This method allows for the inexpensive fabrication and study of PRP shapes that otherwise could not be easily made
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Haynes C.L., Van Duyne R.P. Nanosphere lithography: a versatile nanofabrication tool for studies of size-dependent nanoparticle optics. J. Phys. Chem. B. 105:2001;5599-5611 Reviews the use of nanosphere lithography for the production of PRPs of different shape. This method allows for the inexpensive fabrication and study of PRP shapes that otherwise could not be easily made.
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J. Phys. Chem. B
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Haynes, C.L.1
Van Duyne, R.P.2
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21
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0035748692
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Resonance light scattering particles as ultrasensitive labels for detection of analytes in a wide range of applications
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Reports on the use of PRPs in various biological assays including commercially available DNA microarrays
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Yguerabide J., Yguerabide E. Resonance light scattering particles as ultrasensitive labels for detection of analytes in a wide range of applications. J. Cell Biochem. Supp. 37:2001;71-81 Reports on the use of PRPs in various biological assays including commercially available DNA microarrays.
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Yguerabide, J.1
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23
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Light-scattering submicroscopic particles as highly fluorescent analogs and their use as tracer labels in clinical and biological applications - II. Experimental characterization
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Yguerabide J., Yguerabide E.E. Light-scattering submicroscopic particles as highly fluorescent analogs and their use as tracer labels in clinical and biological applications - II. Experimental characterization. Anal. Biochem. 262:1998;157-176.
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Yguerabide J., Yguerabide E.E. Light-scattering submicroscopic particles as highly fluorescent analogs and their use as tracer labels in clinical and biological applications - I. Theory. Anal. Biochem. 262:1998;137-156.
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25
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0035976235
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Seeding growth for size control of 5-40 nm diameter gold nanoparticles
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Jana N.R., Gearheart L., Murphy C.J. Seeding growth for size control of 5-40 nm diameter gold nanoparticles. Langmuir. 17:2001;6782-6786.
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Langmuir
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Jana, N.R.1
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Murphy, C.J.3
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26
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0033798732
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Seeding of colloidal Au nanoparticle solutions. 2. Improved control of particle size and shape
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Brown K.R., Walter D.G., Natan M.J. Seeding of colloidal Au nanoparticle solutions. 2. Improved control of particle size and shape. Chem. Mater. 12:2000;306-313.
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Brown, K.R.1
Walter, D.G.2
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27
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0034850897
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Evidence for seed-mediated nucleation in the chemical reduction of gold salts to gold nanoparticles
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Jana N.R., Gearheart L., Murphy C.J. Evidence for seed-mediated nucleation in the chemical reduction of gold salts to gold nanoparticles. Chem. Mater. 13:2001;2313-2322.
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Jana, N.R.1
Gearheart, L.2
Murphy, C.J.3
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28
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0035976558
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Photoinduced conversion of silver nanospheres to nanoprisms
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Describes a method of producing a population of triangular silver PRPs that have their plasmon-resonant peak in the red. The fabrication of a population of red PRPs, in conjunction with blue spherical silver PRPs, will allow PRPs to be used in assays that require multiplexing such as in microarray-based RNA differential expression applications
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Jin R.C., Cao Y.W., Mirkin C.A., Kelly K.L., Schatz G.C., Zheng J.G. Photoinduced conversion of silver nanospheres to nanoprisms. Science. 294:2001;1901-1903 Describes a method of producing a population of triangular silver PRPs that have their plasmon-resonant peak in the red. The fabrication of a population of red PRPs, in conjunction with blue spherical silver PRPs, will allow PRPs to be used in assays that require multiplexing such as in microarray-based RNA differential expression applications.
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Science
, vol.294
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Jin, R.C.1
Cao, Y.W.2
Mirkin, C.A.3
Kelly, K.L.4
Schatz, G.C.5
Zheng, J.G.6
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29
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0035820411
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Wet chemical synthesis of silver nanorods and nanowires of controllable aspect ratio
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Jana NR, Gearheart L, Murphy CJ: Wet chemical synthesis of silver nanorods and nanowires of controllable aspect ratio. Chemical Commun 2001:617-618.
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Chemical Commun
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Jana, N.R.1
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30
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0000370720
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Synthesis and characterization of truncated triangular silver nanoplates
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Chen S., Carroll D.L. Synthesis and characterization of truncated triangular silver nanoplates. Nano Letters. 2:2002;1003-1007.
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Nano Letters
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Formation and adsorption of clusters of gold nanoparticles onto functionalized silica nanoparticle substrates
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Westcott S.L., Oldenburg S.J., Lee T.R., Halas N.J. Formation and adsorption of clusters of gold nanoparticles onto functionalized silica nanoparticle substrates. Langmuir. 14:1998;5396.
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Lee, T.R.3
Halas, N.J.4
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36
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0037066862
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Silver nanoshells: Variations in morphologies and optical properties
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Describes a method of producing a population of silver nanoshell PRPs with silica cores that have their plasmon resonant peak in the red. The fabrication of a population of red PRPs, in conjunction with blue spherical silver PRPs, will allow PRPs to be used in assays that require multiplexing such as in microarray-based RNA differential expression applications. It is the first demonstration of a silver nanoshell that produces a well-defined plasmon resonant spectrum
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Jackson J.B., Halas N.J. Silver nanoshells: variations in morphologies and optical properties. J. Phys. Chem. B. 105:2001;2743-2746 Describes a method of producing a population of silver nanoshell PRPs with silica cores that have their plasmon resonant peak in the red. The fabrication of a population of red PRPs, in conjunction with blue spherical silver PRPs, will allow PRPs to be used in assays that require multiplexing such as in microarray-based RNA differential expression applications. It is the first demonstration of a silver nanoshell that produces a well-defined plasmon resonant spectrum.
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J. Phys. Chem. B
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Jackson, J.B.1
Halas, N.J.2
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37
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84974687151
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[Title translation: On optical characteristics of turbid media, with special reference to colloid metallic solutions.]
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Mie G. Beitrage zur Optik truber Medien, Speziell Kolloidaler Metallosungun. Ann. Phys. 25:1908;377-445. [Title translation: On optical characteristics of turbid media, with special reference to colloid metallic solutions.].
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0029342161
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Discrete dipole approximation for calculating extinction and Raman intensities for small particles with arbitrary shapes
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Optical properties of metal nanoparticles and nanoparticle aggregates important in biosensors
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Lazarides A.A., Kelly K.L., Jensen T.R., Schatz G.C. Optical properties of metal nanoparticles and nanoparticle aggregates important in biosensors. J. Mol. Struct.-Theochem. 529:2000;59-63.
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46
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0034809059
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Quantitative and reversible lectin-induced association of gold nanoparticles modified with α-lactosyl-ω-mercapto-poly(ethylene glycol)
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The authors report on the development of a heterobifunctional PEG derivative for stabilizing PRP particles and for anchoring biomolecules to the surface of the PRP. The development of surface chemistry that can be used to firmly attach biomolecules to the surface of metal particles while simultaneously stabilizing the colloidal solution is very important
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Otsuka H., Akiyama Y., Nagasaki Y., Kataoka K. Quantitative and reversible lectin-induced association of gold nanoparticles modified with α-lactosyl-ω-mercapto-poly(ethylene glycol). J. Am. Chem. Soc. 123:2001;8226-8230 The authors report on the development of a heterobifunctional PEG derivative for stabilizing PRP particles and for anchoring biomolecules to the surface of the PRP. The development of surface chemistry that can be used to firmly attach biomolecules to the surface of metal particles while simultaneously stabilizing the colloidal solution is very important.
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J. Am. Chem. Soc.
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Otsuka, H.1
Akiyama, Y.2
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47
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0037092989
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Particles for multiplexed analysis in solution: Detection and identification of striped metallic particles using optical microscopy
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Walton I.D., Norton S.M., Balasingham A., He L., Oviso D.F., Gupta D., Raju P.A., Natan M.J., Freeman R.G. Particles for multiplexed analysis in solution: detection and identification of striped metallic particles using optical microscopy. Anal. Chem. 74:2002;2240-2247.
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Walton, I.D.1
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0001918683
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Preparation of polymer coated gold nanoparticles by surface-confined living radical polymerization at ambient temperature
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Mandal T.K., Fleming M.S., Walt D.R. Preparation of polymer coated gold nanoparticles by surface-confined living radical polymerization at ambient temperature. Nano Letters. 2:2002;3-7.
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Mandal, T.K.1
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49
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0001193601
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Preparation of polystyrene- and silica-coated gold nanorods and their use as templates for the synthesis of hollow nanotubes
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Obare S.O., Jana N.R., Murphy C.J. Preparation of polystyrene- and silica-coated gold nanorods and their use as templates for the synthesis of hollow nanotubes. Nano Letters. 1:2001;601-603.
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Nano Letters
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Obare, S.O.1
Jana, N.R.2
Murphy, C.J.3
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50
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0040029015
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Enhanced thermal stability of silica-encapsulated metal nanoshells
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Describes a method of adding a silica shell to the outside gold surface of a 60-70 nm PRP. The addition of a silica shell to the surface of the PRP allows the use of a broader variety of biomolecule attachment methods, many of which have already been developed for the chemical modification of solid silica particles
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Radloff C., Halas N.J. Enhanced thermal stability of silica-encapsulated metal nanoshells. Appl. Phys. Lett. 79:2001;674-676 Describes a method of adding a silica shell to the outside gold surface of a 60-70 nm PRP. The addition of a silica shell to the surface of the PRP allows the use of a broader variety of biomolecule attachment methods, many of which have already been developed for the chemical modification of solid silica particles.
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Appl. Phys. Lett.
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Radloff, C.1
Halas, N.J.2
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Quaroni L., Chumanov G. Preparation of polymer-coated functionalized silver nanoparticles. J. Am. Chem. Soc. 121:1999;10642-10643.
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Caruso F. Nanoengineering of particle surfaces. Adv. Mater. 13:2001;11-22.
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Caruso, F.1
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53
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0032507285
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One-pot colorimetric differentiation of polynucleotides with single base imperfections using gold nanoparticle probes
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Storhoff J.J., Elghanian R., Mucic R.C., Mirkin C.A., Letsinger R.L. One-pot colorimetric differentiation of polynucleotides with single base imperfections using gold nanoparticle probes. J. Am. Chem. Soc. 120:1998;1959-1964.
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Reynolds R.A., Mirkin C.A., Letsinger R.L. Homogeneous, nanoparticle-based quantitative colorimetric detection of oligonucleotides. J. Am. Chem. Soc. 122:2000;3795-3796.
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Development of an aggregation-based immunoassay for anti-protein A using gold nanoparticles
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Thanh N.T.K., Rosenzweig Z. Development of an aggregation-based immunoassay for anti-protein A using gold nanoparticles. Anal. Chem. 74:2002;1624-1628.
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High-sensitivity detection of DNA hybridization on microarrays using resonance light scattering
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These four papers report on the optical detection of PRPs as reporters for use with DNA microarrays. The reported improvement in nucleic acid detection sensitivity achieved by replacing the more traditional fluorescent label with PRPs suggests that these labels may have broad application in microarray-based experiments
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Bao P., Frutos A.G., Greef C., Lahiri J., Muller U., Peterson T.C., Warden L., Xie X.Y. High-sensitivity detection of DNA hybridization on microarrays using resonance light scattering. Anal. Chem. 74:2002;1792-1797 These four papers report on the optical detection of PRPs as reporters for use with DNA microarrays. The reported improvement in nucleic acid detection sensitivity achieved by replacing the more traditional fluorescent label with PRPs suggests that these labels may have broad application in microarray-based experiments.
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Bao, P.1
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A gold nanoparticle/latex microsphere-based colorimetric oligonucleotide detection method
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Reynolds R.A., Mirkin C.A., Letsinger R.L. A gold nanoparticle/latex microsphere-based colorimetric oligonucleotide detection method. Pure Appl. Chem. 72:2000;229-235.
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Two-color labeling of oligonucleotide arrays via size-selective scattering of nanoparticle probes
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Reports on the use of two different oligonucleotide-functionalized colored PRPs to identify two target sequences in one solution. The ability to identify two different target molecules in one solution is important for applications that require multiplexing capabilities, for example differential RNA expression analysis
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Taton T.A., Mirkin C.A., Letsinger R.L. Two-color labeling of oligonucleotide arrays via size-selective scattering of nanoparticle probes. J. Am. Chem. Soc. 123:2001;5164-5165 Reports on the use of two different oligonucleotide-functionalized colored PRPs to identify two target sequences in one solution. The ability to identify two different target molecules in one solution is important for applications that require multiplexing capabilities, for example differential RNA expression analysis.
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63
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Base pair mismatch recognition using plasmon resonant particle labels
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Identification of nucleotide polymorphisms using a DNA microarray format. The signal is a count of the number of bound PRPs. The limit of detection achieved by counting the number of individual PRPs can surpass that obtained by the measurement of the intensity of light scattered from all bound PRPs
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Oldenburg S.J., Genick C., Clark K., Schultz D.A. Base pair mismatch recognition using plasmon resonant particle labels. Anal. Biochem. 309:2002;109 Identification of nucleotide polymorphisms using a DNA microarray format. The signal is a count of the number of bound PRPs. The limit of detection achieved by counting the number of individual PRPs can surpass that obtained by the measurement of the intensity of light scattered from all bound PRPs.
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Oldenburg, S.J.1
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64
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Submicrometer metallic barcodes
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Reports on the use of multi-segmented metal barcodes as identification tags for use in biological assays
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Nicewarner-Pena S.R., Freeman R.G., Reiss B.D., He L., Pena D.J., Walton I.D., Cromer R., Keating C.D., Natan M.J. Submicrometer metallic barcodes. Science. 294:2001;137-141 Reports on the use of multi-segmented metal barcodes as identification tags for use in biological assays.
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Use of colloidal gold surface plasmon resonance peak shift to infer affinity constants from the interactions between protein antigens and antibodies specific for single or multiple epitopes
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Englebienne P. Use of colloidal gold surface plasmon resonance peak shift to infer affinity constants from the interactions between protein antigens and antibodies specific for single or multiple epitopes. Analyst. 123:1998;1599-1603.
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Synthetic materials capable of reporting biomolecular recognition events by chromic transition
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Englebienne P. Synthetic materials capable of reporting biomolecular recognition events by chromic transition. J. Mater. Chem. 9:1999;1043-1054.
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Using microparticle labeling and counting for attomole-level detection in heterogeneous immunoassay
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Okana K., Takahashi S., Yasuda K., Tokinaga D., Imai K., Koga M. Using microparticle labeling and counting for attomole-level detection in heterogeneous immunoassay. Anal. Biochem. 202:1992;120-125.
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Real-time detection of DNA hybridization and melting on oligonucleotide arrays by using wave guides
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Stimpson D.I., Hoijer J.V., Hsieh W., Jou C., Gordon J., Theriault T., Gamble R., Baldeschwieler J.D. Real-time detection of DNA hybridization and melting on oligonucleotide arrays by using wave guides. Proc. Natl. Acad. Sci. U.S.A. 92:1995;6379-6383.
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Europium nanoparticles and time-resolved fluorescence for ultrasensitive detection of prostate-specific antigen
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Harma H., Soukka T., Lovgren T. Europium nanoparticles and time-resolved fluorescence for ultrasensitive detection of prostate-specific antigen. Clin. Chem. 47:2001;561-568.
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Luminescent quantum dots for multiplexed biological detection and imaging
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Chan W.C.W., Maxwell D.J., Gao X.H., Bailey R.E., Han M.Y., Nie S.M. Luminescent quantum dots for multiplexed biological detection and imaging. Curr. Opin. Biotechnol. 13:2002;40-46.
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Up-converting phosphor reporters for nucleic acid microarrays
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Van de Rijke F., Zijlmans H., Li S., Vail T., Raap A.K., Niedbala R.S., Tanke H.J. Up-converting phosphor reporters for nucleic acid microarrays. Nat. Biotechnol. 19:2001;273-276.
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72
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Temperature-sensitive polymer-nanoshell composites for photothermally modulated drug delivery
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Sershen S.R., Westcott S.L., Halas N.J., West J.L. Temperature-sensitive polymer-nanoshell composites for photothermally modulated drug delivery. J. Biomed. Mater. Res. 51:2000;293-298.
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A nanoscale optical biosensor: Sensitivity and selectivity of an approach based on the localized surface plasmon resonance spectroscopy of triangular silver nanoparticles
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Haes A.J., Van Duyne R.P. A nanoscale optical biosensor: sensitivity and selectivity of an approach based on the localized surface plasmon resonance spectroscopy of triangular silver nanoparticles. J. Am. Chem. Soc. 124:2002;10596-10604.
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Haes, A.J.1
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